The present study investigates the scour at vertical-wall abutments under a strong current-dominated combined wave-current and current-only environment using experiments and computational fluid dynamics (CFD) modeling. The CFD modelling is performed using an open-source three-phase numerical model (REEF3D), which solves Reynolds-Averaged Navier Stokes (RANS) equations with k-ω turbulence closure. The CFD model is first validated using the experiments and then used for further investigation. The Exner equation was used to compute alterations in bed elevation, while the Level-Set method recorded the free surface and bed topography in a realistic manner. The experimental findings demonstrate that the initial phase of scour development is more rapid under combined wave-current flow, but the equilibrium scour depth is higher in current-only conditions. The increase in Keulegan Carpenter (KC) number increases the scour depth at vertical-wall abutments for a specific relative flow velocity (Ucw). In contrast, a mild increase in vertical-wall abutment scour depth is observed with an increase in Ucw. To the best of the authors’ knowledge, the present work is the first of a kind of experimental and three-dimensional CFD study that estimates abutment scour under strong current-dominated combined wave-current flow.