Beam Size Research Articles

Radiation-quality-dependent bystander cellular effects induced by heavy-ion microbeams through different pathways.

We investigated the radiation-quality-dependent bystander cellular effects using heavy-ion microbeams with different ion species. The heavy-ion microbeams were produced in Takasaki Ion Accelerators for Advanced Radiation Application, National Institutes for Quantum Science and Technology. Carbon (12C5+, 220MeV), neon (20Ne7+, 260MeV) and argon (40Ar13+, 460MeV) ions were used as the microbeams, collimating the beam size with a diameter of 20μm. After 0.5and 3h of irradiation, the surviving fractions (SFs) are significantly lower in cells irradiated with carbon ions without a gap-junction inhibitor than those irradiated with the inhibitor. However, the same SFs with no cell killing were found with and without the inhibitor at 24h. Conversely, no cell-killing effect was observed in argon-ion-irradiated cells at 0.5 and 3h; however, significantly low SFs were found at 24h with and without the inhibitor, and the effect was suppressed using vitamin C and not dimethyl sulfoxide. The mutation frequency (MF) in cells irradiated with carbon ions was 8- to 6-fold higher than that in the unirradiated control at 0.5 and 3h; however, no mutation was observed in cells treated with the gap-junction inhibitor. At 24h, the MFs induced by each ion source were 3- to 5-fold higher and the same with and without the inhibitor. These findings suggest that the bystander cellular effects depend on the biological endpoints, ion species and time after microbeam irradiations with different pathways.

High-resolution 3D grain orientation mapping by inclined scanning 3D X-ray diffraction microscopy

The microstructure of a material plays a crucial role in determining its mechanical and chemical properties, as well as in predicting potential malfunctions. In polycrystalline materials, the orientation of each grain has a significant impact on the material's properties. It is thus imperative to conduct non-destructive 3D observations of the grain orientation with high resolution. This study presents a novel method to enhance the spatial resolution of 3D grain orientation maps in scanning 3D X-ray diffraction (S3DXRD) microscopy beyond the size of the probe beam. The new method, inclined scanning 3D X-ray diffraction (iS3DXRD) microscopy, combines an inclined geometry for the rotation axis of the object with the concept of `sub-voxel' analysis, where the voxel is subdivided into smaller pieces. The validity of the method was verified for a polycrystalline α-Fe wire using a 37 keV X-ray beam with a size of 10 × 20 µm (horizontal × vertical), and it successfully produced a high-resolution 3D grain orientation map with a spatial resolution of about 2.5 µm. The method can provide complex details on the microstructure of a polycrystalline material, which will pave the way for precise prediction of the material's properties.

Exploring beam size measurement based on the Talbot effect at BEPCII.

Vertical beam size measurements were carried out at Beijing Electron-Positron Collider II (BEPCII) using a phase grating and an absorption grating based on the Talbot effect. The transverse coherence of synchrotron radiation is closely related to beam size. Due to the partial coherence of the synchrotron radiation source, the coherence length can be calculated by measuring the visibility decay of interferograms recorded at different distances behind the gratings. A vertical beam size of 68.19 ± 2 µm was obtained based on the relationship between the coherence length and beam size at the 3W1 beamline of BEPCII. A comparison of the vertical emittance derived from the grating Talbot method and the synchrotron radiation visible light interferometer method was presented. The vertical emittances from the two methods are 1.41 nm rad and 1.40 nm rad, respectively. The 0.1% difference indicates that the grating Talbot method for beam size measurement is reliable. This technique has great potential for small beam size measurement of fourth-generation synchrotron radiation light sources, considering its small diffraction limitation and simple experimental setups.

Silicon-nitride-based entrance slit design for the high-power-density monochromator in TPS 45A.

Details of the design and operational status of the silicon-nitride-based entrance slit installed in the Taiwan Photon Source (TPS) 45A beamline are given. The slit is a diamond blade edge etched onto a copper slit part, which is in thermal contact with the silicon nitride base. A stable slit opening smaller than 4 µm is achieved in TPS 45A. The beam size at the slit has a full width at half-maximum of 3 µm in the vertical direction with a power of 20 W. Additionally, a hard stop made of invar is incorporated to control the thermal expansion displacement. The slit reduces the size and increases the stability of the source of the monochromator. Consequently, a higher energy resolution and excellent beamline stability are achieved.

Extreme transport of light in spheroids of tumor cells

Extreme waves are intense and unexpected wavepackets ubiquitous in complex systems. In optics, these rogue waves are promising as robust and noise-resistant beams for probing and manipulating the underlying material. Localizing large optical power is crucial especially in biomedical systems, where, however, extremely intense beams have not yet been observed. We here discover that tumor-cell spheroids manifest optical rogue waves when illuminated by randomly modulated laser beams. The intensity of light transmitted through bio-printed three-dimensional tumor models follows a signature Weibull statistical distribution, where extreme events correspond to spatially-localized optical modes propagating within the cell network. Experiments varying the input beam power and size indicate that the rogue waves have a nonlinear origin. We show that these nonlinear optical filaments form high-transmission channels with enhanced transmission. They deliver large optical power through the tumor spheroid, and can be exploited to achieve a local temperature increase controlled by the input wave shape. Our findings shed light on optical propagation in biological aggregates and demonstrate how nonlinear extreme event formation allows light concentration in deep tissues, paving the way to using rogue waves in biomedical applications, such as light-activated therapies.

The design and characterization of a novel dynamic collimator system for synchrotron radiotherapy applications.

Novel synchrotron radiotherapy techniques are currently limited to using prefabricated beam-limiting blocks for field definition. For large experiments, a single square tungsten block is often used for every treatment since conformal blocks are both patient and field specific, and require long lead times for fabrication. Future synchrotron radiotherapy treatments would benefit from a dynamic collimatorsystem. We developed and tested a novel collimator design for use on the Imaging and Medical Beamline (IMBL) at the ANSTO AustralianSynchrotron. The maximum usable beam size on IMBL is 50-mm wide by 3-mm tall. Given the beam shape, targets must be vertically scanned through the synchrotron beam to cover the target volume. To shape the beam, a novel collimator design was developed, consisting of two semi-circular leaves made from 4-mm thick tungsten sheets, with each leaf capable of both vertical and horizontal movement. A software model was created to optimize motor trajectories and generate deliverable treatment fields. A series of geometric field shapes and clinical target volumes were delivered using the collimator and imaged with a digital imaging detector. Four similarity metrics (volumetric similarity, DICE, and the average and maximum Hausdorff distances) were used to measure differences between the input and planned fields, and the planned and deliveredfields. Differences between input and planned fields increased with delivery speed, and were worse for rectangular and square fields compared to circular fields. However, the differences between planned and delivered fields were small, where the maximum average deviation between the fields was 0.25mm (one pixel). Field repeatability was consistent with no difference (σ = 0 for all metrics) observed in consecutively deliveredfields. We have successfully built and demonstrated a novel collimator for synchrotron radiotherapy applications on IMBL. Several design improvements have been highlighted and will be addressed in future revisions the collimator. However, in its current state, the collimator enables dynamically delivered conformal treatment fields to be utilized on IMBL, and is ready to support the forthcoming canine treatments on IMBL.

A Quick Look at the 3 GHz Radio Sky. II. Hunting for DRAGNs in the VLA Sky Survey

Active galactic nuclei (AGNs) can often be identified in radio images as two lobes, sometimes connected to a core by a radio jet. This multicomponent morphology unfortunately creates difficulties for source finders, leading to components that are (a) separate parts of a wider whole, and (b) offset from the multiwavelength cross identification of the host galaxy. In this work we define an algorithm, DRAGNhunter, for identifying double radio sources associated with AGNs (DRAGNs) from component catalog data in the first epoch Quick Look images of the high-resolution (≈3″ beam size) Very Large Array Sky Survey (VLASS). We use DRAGNhunter to construct a catalog of >17,000 DRAGNs in VLASS for which contamination from spurious sources is estimated at ≈11%. A “high-fidelity” sample consisting of 90% of our catalog is identified for which contamination is <3%. Host galaxies are found for ≈13,000 DRAGNs as well as for an additional 234,000 single-component radio sources. Using these data, we explore the properties of our DRAGNs, finding them to be typically consistent with Fanaroff–Riley class II sources and to allow us to report the discovery of 31 new giant radio galaxies identified using VLASS.

Design of structure and control system based on achromatic rotating biprism

The achromatic rotating dual-prism beam pointing system is mostly used in space laser communication, which needs to meet the characteristics of small size and light mass. To address the problems of the large size, heavy mass and low accuracy of the conventional beam, this paper uses SOLIDWORKS to build a dual-optical wedge prism model and the structural model of the optical machine and simulates and analyses its environmental performance. The design of the control system effectively improves the beam-pointing accuracy of the whole machine. A reference value is provided for the study of rotating biprism.

Flexural Behavior of Reinforced Rubberized Reactive Powder Concrete Beams under Repeated Loads

Non-biodegradability of rubber tires contributes to pollution and fire hazards in the natural environment. In this study, the flexural behavior of the Rubberized Reactive Powder Concrete (RRPC) beams that contained various proportions and sizes of scrap tire rubber was investigated and compared to the flexural behavior of the regular RPC. Fresh properties, hardened properties, load-deflection relation, first crack load, ultimate load, and crack width are studied and analyzed. Mixes were made using micro steel fiber of the straight type, and they had an aspect ratio of 65. Thirteen beams were tested under two loading points (Repeated loading) with small-scale beams (1100 mm, 150 mm, 100 mm) size. The fine aggregate is replaced by 5, 10, and 15%, respectively, with crumb rubber. While replacement of silica fume was 10, 20, 30, and 50%, respectively, with very fine rubber. Also, chip rubber was added to the mixture as coarse aggregate with 5, 10, and 15%. Five tested beams were chosen as case studies to analyze and compare the results of the ABAQUS software with the experimental results. The results showed that the flexural behavior of RRPC beams that contains rubber was acceptable when compared with the flexural behavior of the RPC beam (depending on load-carrying capacity). The crack width was decreased by including waste rubber and steel fibers. There is a satisfactory agreement between the results of the numerical analysis and the results of the experimental testing. Slight ultimate load differences are targeted between the effects of the monotonic loading and the repeated loading.

Subarcsecond-resolution Imaging of M51 with the International LOFAR Telescope

We present an International LOFAR Telescope (ILT) subarcsecond-resolution image of the nearby galaxy M51 with a beam size of 0.″436 × 0.″366 and rms of 46 μJy. We compare this image with a European VLBI Network study of M51 and discuss the supernovae in this galaxy, which have not yet been probed at these low radio frequencies. We find a flux density of 0.97 mJy for SN 2011dh in the ILT image, which is about five times smaller than the flux density reported by the LOFAR Two-metre Sky Survey (LoTSS) at 6″ resolution using the same data set without the international stations. This difference makes evident the need for LOFAR international baselines to reliably obtain flux density measurements of compact objects in nearby galaxies. Our LOFAR flux density measurement of SN 2011dh directly translates into fitting the radio light curves for the supernova and constraining the mass-loss rates of the progenitor star. We do not detect two other supernovae in the same galaxy, SN 1994I and SN 2005cs, and our observations place limits on the evolution of both supernovae at radio wavelengths. We also discuss the radio emission from the center of M51, in which we detect the active galactic nucleus and other parts of the nuclear emission in the galaxy, with a possible detection of Component N. We discuss a few other sources, including the detection of a high-mass X-ray binary not detected by LoTSS but with a flux density in the ILT image that matches well with higher-frequency catalogs.

Multi-resolution Correlative Ultrastructural and Chemical Analysis of Carious Enamel by Scanning Microscopy and Tomographic Imaging.

Caries, a major global disease associated with dental enamel demineralization, remains insufficiently understood to devise effective prevention or minimally invasive treatment. Understanding the ultrastructural changes in enamel is hampered by a lack of nanoscale characterization of the chemical spatial distributions within the dental tissue. This leads to the requirement to develop techniques based on various characterization methods. The purpose of the present study is to demonstrate the strength of analytic methods using a correlative technique on a single sample of human dental enamel as a specific case study to test the accuracy of techniques to compare regions in enamel. The science of the different techniques is integrated to genuinely study the enamel. The hierarchical structures within carious tissue were mapped using the combination of focused ion beam scanning electron microscopy with synchrotron X-ray tomography. The chemical changes were studied using scanning X-ray fluorescence (XRF) and X-ray wide-angle and small-angle scattering using a beam size below 80 nm for ångström and nanometer length scales. The analysis of XRF intensity gradients revealed subtle variations of Ca intensity in carious samples in comparison with those of normal mature enamel. In addition, the pathways for enamel rod demineralization were studied using X-ray ptychography. The results show the chemical and structural modification in carious enamel with differing locations. These results reinforce the need for multi-modal approaches to nanoscale analysis in complex hierarchically structured materials to interpret the changes of materials. The approach establishes a meticulous correlative characterization platform for the analysis of biomineralized tissues at the nanoscale, which adds confidence in the interpretation of the results and time-saving imaging techniques. The protocol demonstrated here using the dental tissue sample can be applied to other samples for statistical study and the investigation of nanoscale structural changes. The information gathered from the combination of methods could not be obtained with traditional individual techniques.

Fracture Energy Measurement in Different Concrete Grades

Fracture energy is regarded as an intrinsic (material) properties that dominates crack mechanisms and associated crack growth in concrete damage under applied stress. In recent times, significant advancements in computing technology have driven the adoption of finite element analysis (FEA) methodologies that necessitate the integration of constitutive models, includingthe traction-separation relationship derived from cutting-edge fracture mechanics. A physically-based model requires fracture energy values; therefore, a properly measured fracture energy value is essential to exhibit better structure response within FEA models. There are large arrays of parameters involved during the concrete mixture, such as beam size effect, aggregate size, and concrete grade, that affect the flexural resistance of the concrete. The fracture and failure in concrete ahead of the crack tip are represented by fracture energy values where micro-damage events such as interfacial failure, fiber-bridging, and matrix cracking occurred.This study aims to determinethe fracture energy of concrete specimens with combination of notch depth aoat mid-span, design concrete strength as specified in the testing series. Independent compression strength, fcand measured load-displacement profiles underathree-point bendingtest were used to determine fracture energy by incorporating three available fracture energy expressions such as Bazant, Hillerborg,and CEB-FIP models.

Three-dimensional micro-X-ray topography using focused sheet-shaped X-ray beam

X-ray topography is a powerful method for analyzing crystal defects and strain in crystalline materials non-destructively. However, conventional X-ray topography uses simple X-ray diffraction images, which means depth information on defects and dislocations cannot be obtained. We have therefor developed a novel three-dimensional micro-X-ray topography technique (3D μ-XRT) that combines Bragg-case section topography with focused sheet-shaped X-rays. The depth resolution of the 3D μ-XRT depends mainly on the focused X-ray beam size and enables non-destructive observation of internal defects and dislocations with an accuracy on the order of 1 μm. The demonstrative observation of SiC power device chips showed that stacking faults, threading screw, threading edge, and basal plane dislocations were clearly visualized three-dimensionally with a depth accuracy of 1.3 μm. 3D μ-XRT is a promising new approach for highly sensitive and non-destructive analysis of material crystallinity in a three-dimensional manner.

Effect of oxygen fugacity on the storage of water in wadsleyite and olivine in H and H–C fluids and implications for melting atop the transition zone

Abstract. This study aims to experimentally constrain the water storage capacities of olivine and wadsleyite at a depth near 410 km (12–14 GPa) under water-saturated conditions, as a function of temperature, oxygen fugacity, and the presence of carbon (molar H / C of 2). Experiments have been conducted in the multi-anvil press, with sealed double capsules to preserve fluids, at 1200 to 1400 ∘C and three different oxygen fugacities fixed at the rhenium–rhenium oxide buffer (RRO), nickel–nickel oxide buffer (NNO), and iron-wüstite (IW) for oxidizing, intermediate, and reducing conditions, respectively. The water contents of minerals were measured by Raman spectroscopy that allows a very small beam size to be used and were cross-checked on a few samples with NanoSIMS analyses. We observe an effect, although slight, of fO2 on the water storage capacity of both wadsleyite and olivine and also on their solidus temperatures. At 1200 ∘C, the storage capacity of the nominally anhydrous minerals (NAMS) increases with increasing oxygen fugacity (from the IW to the RRO buffer) from 1 wt % to 1.5 wt % H2O in wadsleyite and from 0.1 wt % to 0.2 wt % in olivine, owing to the increase in H2O / H2 speciation in the fluid, whereas at 1400 ∘C the storage capacity decreases from 1 wt % to 0.75 wt % H2O in wadsleyite and down to 0.03 wt % for olivine. At high temperature, the water storage capacity is lowered due to melting, and the more oxidized the conditions are the more the solidus is depressed. Still, at 1400 ∘C and IW, wadsleyite can store substantial amounts of water: 0.8 wt % to 1 wt % H2O. The effect of carbon is to decrease water storage capacity in both wadsleyite and olivine by an average factor 2 at 1300–1400 ∘C. The trends in water storage as a function of fO2 and C presence are confirmed by NanoSIMS measurements. The solidus at IW without C is located between 1300 and 1400 ∘C in the wadsleyite stability field and drops to temperatures below 1300 ∘C in the olivine stability field. With the addition of C, the solidus is found between 1200 and 1300 ∘C in both olivine and wadsleyite stability fields.

3D Modelling and Simulation Methods in RCC Building using Bim Software

The building can be designed by using Autodesk Revit Software. Autodesk Revit is Building Information Modelling (BIM) software for, landscape architects, structural engineers, MEP engineers and contractors. The software allows users to design a building and its components in 3D annotate the model with 2D drafting elements and access building information from the building model’s database. Our structure are G+14 Residential building and LIC Ludhiana projects. G+14 is the residential project in which there are 10 blocks with 2 basement, shops on ground and 1st floor, and typical floors from 3rd to 13th floor level which also consist of two refuges floor, the project has different AutoCAD plan of architectural and structural layout having sizes of Beam, column, slabs designed according to IS456:2000 and IS800:2007 LSM. In LIC Ludhiana project the work consist of Rebaring of slabs which includes the top and bottom rebar’s of slab having different diameter or sizes of rebar’s like 8mm, 10mm, 12mm etc. The schedule can be easily extract from this Revit models which will calculate the quantity of material required for the construction purposes. The extensions or plugins like Diroots, Dynamo run in Revit reduces the time of project and give more accuracy to provide id’s to the elements.

ANALISIS PERKUATAN STRUKTUR AKIBAT PERUBAHAN FUNGSI RUANG DAN PENAMBAHAN JUMLAH LANTAI PROYEK RUMAH IBADAH YAYASAN BEREA KARAWACI, TANGERANG

Aspects of building construction are impacted by population increase, technological advancements, and the growing needs of the community. Existing buildings may be converted to serve new purposes in an effort to meet space needs, particularly in key areas. The Barea Karawaci Foundation house of worship building, located in Tangerang City, has a structure that ranges in height from four to six stories, and its usage has changed from that of a shophouse to a place of worship. This is a choice since it is quicker to execute and more financially lucrative. After adding floors and modifying a room's purpose, the inspection of the existing structure is done using the ETABS program and manually computed against the fulfillment of the regulations' requirements. The same is done for reinforcement with concrete jacketing. By enlarging the beam's size from 200x400 to 400x500, adding 6D19 flexural reinforcement, and adding 10 shear reinforcement at intervals of 90 to 200 mm, the beam is strengthened. Column reinforcement is done by enlarging the column from 200x600 to 400x800, adding 18D13 and 14D13 reinforcement, and adding D10 shear reinforcement at distances ranging from 78 mm to 200 mm.

Optimized terahertz pulse generation with chirped pump pulses from an echelon-based tilted-pulse-front (TPF) scheme.

We successfully demonstrated the generation of single-cycle terahertz (THz) pulses through tilted-pulse-front (TPF) pumping using a reflective echelon in a lithium niobate crystal. By optimizing the pump pulse duration using a chirp, we achieved a maximum pump-to-THz conversion efficiency of 0.39%. However, we observed that the saturation behavior began at a relatively low pump energy (0.37 mJ), corresponding to a pump intensity of 22 GW/cm2. To elucidate this behavior, we measured the near- and far-field THz beam profiles and found variations in their beam characteristics, such as the beam size, location, and divergence angle in the plane of the tilted pulse direction, with the pump energy (intensity). This nonlinear behavior is attributed to the reduced effective interaction length, which ultimately leads to the saturation of THz generation. The results obtained from our study suggest that it is feasible to develop an effective THz source using echelon-based TPF pumping while also considering the impact of nonlinear saturation effects.

Impact of beam size and diffraction effects in the measurement of long-range electric fields in crystalline samples via 4DSTEM

Measuring long-range electric fields by 4-dimensional scanning transmission electron microscopy (4DSTEM) is on the verge to becoming an established method, though quantifying and understanding all underlying processes remains a challenge. To gain further insight into these processes, experimental studies employing the center-of-mass (COM) method of the model system of a GaAs p-n junction are carried out in which three ranges of the semi-convergence angle α are identified, with an intermediate one where measuring the built-in potential Vbi is not feasible. STEM multislice simulations including both atomic and nm-scale fields prove that this intermediate range begins once diffraction disks start overlapping with the undiffracted beam. The range ends when the diffraction disks’ intensities become so low that they do not affect the measurement significantly anymore and when high-intensity diffractions overlap the center disk completely. From simulations without influence of atoms it is concluded that measuring Vbi has advantages over measuring the electric-field strength, as the potential difference does neither show a significant dependence on the beam size, nor on the specimen thickness.

Measured and projected beam backgrounds in the Belle II experiment at the SuperKEKB collider

The Belle II experiment at the SuperKEKB electron–positron collider aims to collect an unprecedented data set of 50ab−1 to study CP-violation in the B-meson system and to search for Physics beyond the Standard Model. SuperKEKB is already the world’s highest-luminosity collider. In order to collect the planned data set within approximately one decade, the target is to reach a peak luminosity of 6 × 1035cm−2s−1 by further increasing the beam currents and reducing the beam size at the interaction point by squeezing the betatron function down to βy∗=0.3mm. To ensure detector longevity and maintain good reconstruction performance, beam backgrounds must remain well controlled. We report on current background rates in Belle II and compare these against simulation. We find that a number of recent refinements have significantly improved the background simulation accuracy. Finally, we estimate the safety margins going forward. We predict that backgrounds should remain high but acceptable until a luminosity of at least 2.8 × 1035cm−2s−1 is reached for βy∗=0.6mm. At this point, the most vulnerable Belle II detectors, the Time-of-Propagation (TOP) particle identification system and the Central Drift Chamber (CDC), have predicted background hit rates from single-beam and luminosity backgrounds that add up to approximately half of the maximum acceptable rates.

Anatomical changes in the male pelvis between the supine and upright positions-A feasibility study for prostate treatments in the upright position.

Treating and imaging patients in the upright orientation is gaining acceptance in radiation oncology and radiology and has distinct advantages over the recumbent position. An IRB approved study to investigate the positions and orientations of the male pelvic organs between the supine and upright positions was conducted. The study comprised of scanning 15 male volunteers (aged 55-75 years) on a 0.6 T Fonar MRI scanner in the supine and upright positions with a full bladder and in the upright position with an empty bladder. The Pelvic study revealed that in the upright position the 1. Position and shape of the prostate are not impacted significantly by bladder fill. 2. Distance between the sacrum and the anterior bladder wall is significantly smaller. 3. Anterior-Posterior length and the bladder width is significantly larger. 4. Seminal vesicles are pushed down by the bladder. 5. Top of the penile bulb is further away from the apex of the prostate. These observed differences could positively impact upright prostate treatments by 1. Reducing the risk of small bowel approximating the treatment volume. 2. Prostate treatments can be done with a reduced focus on bladder fill. 3. Radiation beams for treating intermediate risk prostrate can be made smaller or a larger portion of the seminal vesicles can be treated with the same beam size than typically used for supine treatments. 4. Reducing the average dose to the penile bulb.