Interacting with surrounding road users is a key feature of autonomous vehicles and is critical for their intelligence testing. Existing interaction modalities in autonomous vehicle simulation and testing are not sufficiently smart, and they barely reflect human‐like behaviors in real‐world driving scenarios. Therefore, a novel hierarchical game‐theoretical framework is presented to represent naturalistic multimodal interactions among road users during simulation and testing, which is subsequently validated by the Turing test. Given that human drivers have no access to the complete information of the surrounding road users, the Bayesian game theory is used to model the decision‐making process. Next, a probing behavior is generated by the proposed game‐theoretic model, and is further applied to control the vehicle via the Markov chain. The proposed method is tested through a series of experiments and compared with existing approaches. In addition, Turing tests are conducted to quantify the human‐likeness of the proposed algorithm. The experimental results show that the proposed Bayesian game‐theoretic framework can effectively generate representative scenes of human‐like decision‐making during autonomous vehicle interactions, demonstrating its feasibility and effectiveness. An interactive preprint version of the article can be found at: https://www.authorea.com/doi/full/10.22541/au.163482630.00283278.