Basic Perspective Research Articles

Growth hormone and bone: a basic perspective.

Growth hormone is fundamental for growth during childhood and for maintaining bone mass and homeostasis in the adults. GH deficiency causes decreased bone growth and osteopenia, whereas GH excess causes increased bone fragility and decreased bone quality. In the past, it was common knowledge that GH effects on the skeletal system were due to the production of IGF1 from the liver, which has a huge bone anabolic effect per se. However, with the progress of basic research techniques new light has been shed on the mechanisms underlying GH effect in bone, and it is now clear that GH has effects that go beyond the downstream activation of liver IGFs. Therefore, the purpose of this review is to summarize the milestones in basic research that led to the discovery of GH local activity on bone.

Biopreservation and the Safety of Fish and Fish Products, the Case of Lactic Acid Bacteria: A Basic Perspective

Biopreservation and the Safety of Fish and Fish Products, the Case of Lactic Acid Bacteria: A Basic Perspective

Algorithm for detecting abnormal electricity usage by customers based on electricity big data and deep learning

Abstract In order to optimize the effect of individuals’ aberrant power utilization detection and reinforce the recognition rate and accuracy of abnormal power consumption detection of electricity use, an aberrant power utilization identification algorithm based on electric power big data and deep learning is proposed. Taking the two-way dialogue between power users and the power company as the basic perspective, real-time monitoring and collection of power consumption dynamics of users is carried out, and the power big data collection framework is designed. The retrieval of aberrant power utilization detection indexes is completed. Based on the deep learning algorithm, the artificial neural network base operation medium is combined to quantitatively solve the aberrant power utilization indexes, completing the design of a user aberrant power utilization detection algorithm. Experimental results show that the accuracy of the designed algorithm is 0.963, the F1 value is 0.985, and the AUC value is 0.942, which can effectively identify the aberrant power utilization and has a better performance of abnormal power consumption identification and detection.

독일 헌법사에서 법률유보의 의의

This study examines the development of major theories related to legal reservationin Germany from a constitutional perspective and presents implications and challenges toKorean public law from the basic perspective seen in the discussion of German public law onlegal reservation. In order to achieve the above research objectives, a literature researchmethod is attempted to review the books, papers, and precedents of Korea, Japan, and Germany on this topic. In the early days, the realm of legal reservation was limited to limitedbasic rights such as individual freedom and property rights, and its main significance was tosecure the legislative realm of the representative body, the parliament, from the executivepower of the administration. However, since then, the center of the discussion on legalreservation in Germany has emphasized the substantive discipline of administrative activitiesby law, trying to control administrative power under the detailed discipline density necessaryto achieve the purpose of protecting the rights and interests of the people. And today, legalreservation is not just a control principle of administrative power, but also a constitutionalprinciple. As such a constitutional principle, the basic perspective seen in the discussion ofGerman public law on legal reservation has great implications for us, in particular, as aconstitutional principle, efforts to promote an organic interpretation of related provisions in theconstitution based on legal reservation are one of the important tasks of Korean public law inthe future.

Association Between Atopic Dermatitis and Aging: Clinical Observations and Underlying Mechanisms.

As one of the most prevalent chronic inflammatory skin diseases, atopic dermatitis (AD) increasingly affects the aging population. Amid the ongoing global aging trend, it's essential to recognize the intricate relationship between AD and aging. This paper reviews existing knowledge, summarizing clinical observations of associations between AD and aging-related diseases in various systems, including endocrine, cardiovascular, and neurological. Additionally, it discusses major theories explaining the correlation, encompassing skin-mucosal barriers, systemic inflammation and stress, genes, signal transduction, and environmental and behavioral factors. The association between AD and aging holds significant importance, both in population and basic perspectives. While further research is warranted, this paper aims to inspire deeper exploration of inflammation/allergy-aging dynamics and the timely management of elderly patients with AD.

Analysis of the Effect of Tax Planning, Deferred Tax Burden, and Company Size on Profit Management

Researchers want to re-evaluate data on different units and also the Covid-19 pandemic which has caused several sectors to experience a significant increase in the company's profits. To analyze the effect of tax planning, deferred tax expense, and company size on earnings management. In the basic perspective to understand the concept of earnings management, the organization has several agreements, for example an employment contract between the organization and its directors and an advance agreement between the organization and its bank. Where between the head and management need to expand the utility of each with the data they have. However, again Management has more data than heads, causing data to be unbalanced. In this study using purposive sampling technique, the number of sample data used in this study were 24 companies from the Indonesia Stock Exchange in the goods and consumption sub-sector. does not affect earnings management, Deferred tax burden has an effect on earnings management. With the conclusion that the greater the profit earned, the greater the tax to be imposed on the company, and vice versa. So the company should continue to do tax planning as an effort to minimize the company's taxable profit, because this is legal in the eyes of the State.

From allegory to figure and back again

The aim of the article is to clarify the basic perspective that Immagini cristiane e cultura antica adopted to read the relationship between early Christian iconographic production – the main subject of the book – and the development of the forms of later figurative art, as well as the path leading to modern aesthetics.For this purpose, the article compares the positions of Auerbach – that had an explicit influence on the book – with those of Benjamin, regarding the different ways in which the two Berliner authors interpreted the meaning and the function of allegory. In Auerbach, allegory is understood as the past of the figura whose logic, according to Immagini cristiane e cultura antica, underlies not only the Christian literary production of the first centuries, but also the figurative one. In Benjamin, conversely, allegory is understood as the future of the figura, followed to the definitive crisis of Christian messianism.

Taking empirical evidence seriously v.2.01

AbstractThis article discusses the status and challenges related to the basic perspective of knowledge and science in systemic practice. This article points out that some parts of the field (i.e. collaborative dialogical practice) have a preference for knowledge obtained through qualitative rather than quantitative studies. This is problematised, partly based on methodology and partly on the bias this entails in the provision of knowledge to students and systemic practitioners. The consequences of such a preference may be that systemic practitioners will lack significant knowledge, and that they are not encouraged to conduct or participate in quantitative studies. This issue highlights a stronger focus on the field's basic perspectives, as well as key political, ethical and professional policies. In response, the article presents the theories of interactive constructivism and critical realism and proposes that these become the guiding paradigm for systemic practice.

Responses to "A Review of the Book 'Minamata Disease and the Responsibility of Medical Authorities'"

Drs. Futatsuka, Eto, and Uchino expressed their opinions in the Journal of the Japanese Society for Hygiene in the form of a review of my book, "Minamata Disease and the Responsibility of Medicine." (The reviewers translated it as "Responsibility of Medical Authorities," but for my purposes in writing this book, I believe it should be translated as "Responsibility of Medicine.") The nine major comments of the three reviewers described in this book review were reviewed from the basic perspective of toxicology, epidemiology, and neuroscience. This book review is fraught with either medical, logical, or ethical problems in all the nine points as follows: (1) the inadequate way in which exposure and health hazards are considered from the toxicological perspective, (2) problems in interpreting epidemiological information, (3) the failure to consider recent achievements in methylmercury toxicosis studies, (4) presenting the reviewers' own theories without regard to the content of my book while calling it a "book review," (5) presenting and criticizing what Takaoka does not claim as if he does, and (6) making claims that are inconsistent with the three reviewers' own views. The problems with this book review will become even clearer when you read "Minamata Disease and the Responsibility of Medicine" itself.

Teaching with Conceptual Metaphors: A Cognitive linguistic approach to Japanese Idioms Teaching

In recent studies, the importance of developing metaphorical competence for L2 learners has been highlighted by many cognition linguists. Applying metaphor instruction in language education is increasingly considered as an effective way of improving language teaching. This paper discusses the underlying metaphorical structures and semantic construction of Japanese idiomatic expressions centered on idioms of human body. Based on that, this paper attempts to explore some strategies for Japanese idioms teaching to Chinese JFL learners from the basic perspectives of conceptual metaphors.

Necessitated Strategies and Skills in Learning Sight Translation

This paper studies Sight Translation (SiT) and how this type of translation is conducted to render a written text into a spoken message in the target language. It also highlights the most frequent strategies and skills that students need to perform SiT successfully. This paper focuses on the most significant stages of SiT, which are conducted sequentially. This paper reviews categories of SiT that can be seen in different contexts. This descriptive study presents details to illustrate the significant effectiveness of these strategies and how the students can employ their skills to overcome SiT problems. This paper explains this challenging task and the basic perspectives that are needed by the students to improve their performance in SiT.

LVPRESSURIZATION SYSTEMS OF PROPELLANT TANKS AND PROSPECTS OF THEIR DEVELOPMENT

The experience of domestic and world rocket manufacturing is considered with interesting from the point of view of the used engineering solutions. Positive and negative sides of the introduced solutions are shown.
 The basic perspective directions of their development are shown among variety of the considered PSs. To them concern: increase of specific function ability of a pressurant gas; improvement physical-chemical and thermal-mass processes, occurring in a tank; regulation and correlation relation of PS parameters; rational selection of a design of pressurization devices; feature of PS experimental development and modelling. In the whole, their use results to increase of LV energy characteristics.

Criminal Responsibilities Or Political Partners As Corporations In Corruption Criminal Action And Money Laundering Criminal Acts

The existence of political parties plays a strategic role in the development of democracy and the nation is faced with a number of issues that create a negative impression on these organs, some of which include; first, the problem of involvement of political parties in various cases of corruption and money laundering crimes that have an impact on the fall of public image and trust in the organization; second, the problem of pro and contra accountability of political parties involved in cases of corruption and criminal acts of money laundering before the law; and third, the issue of imposing criminal sanctions on political parties as the subject of corporate offenses known in corruption and money laundering. This research belongs to the typology of juridical normative legal research with secondary data types in the form of primary, secondary and tertiary legal materials. The approach taken includes the comparison, conceptual, statutory, and philosophical approaches, and analyzed descriptively qualitatively through literature. The results of the study show that; first, the justification of political parties as corporations in criminal acts of corruption and criminal acts of money laundering can be seen in five basic perspectives, namely philosophical foundation, juridical basis, historical basis, sociological basis, and political foundation of criminal law; second, the ideal concept of political party punishment as a corporation is carried out with a reconceptualization of the subject of corporate delictions in the affirmation of two types of corporations, namely corporations in the form of private and special corporations or in the form of public with different provisions on punishment arrangements. The need for an amendment to some provisions of the Corruption Law and the TPPU Law related to corporations in accommodating the two types of corporations into a forum for the implementation of ideas, of course issuing a law that contains specific provisions regarding special corporate punishment can be the answer to a myriad of issues regarding criminalization

Discussion on the Scientific Research Cooperation Network of Local Colleges and Universities -- Based on the Perspective of Knowledge Governance


 
 
 
 In recent years, many scholars at home and abroad have carried out relevant research work on scientific research cooperation, but the social network analysis method is commonly used, and the literature on research cooperation network of local universities is relatively small and lacks a systematic theory. Taking knowledge governance as the basic perspective, we analyze the existing research on scientific research cooperation, carry out the analysis of the necessity and feasibility of establishing scientific research cooperation network in colleges and universities, and take 10 colleges and universities in Fujian Province as samples to explore the existing problems of scientific research cooperation network in local colleges and universities, so as to provide theoretical support and new perspectives for the level of scientific and technological innovation and service capability of colleges and universities to enhance the competitiveness of college education.
 
 
 
 

세키노 타다시의 한국 고적 조사에 대한 시각 검토 - 실증적 조사에 내포된 이데올로기적 기반

In association with the issue for establishing the Japanese Empire, the scientific discourse for objectifying the Japanese Annexation of Korea in the Pre-WWII era was one of the most important issues to the Japanese intellectuals. Japanese thinkers, anthropologists and historians discussed various scientific and historical reasons to the colonial origin of the Koreans. Sekino Tadashi was not a thinker who joined in the ideological debates for creating the colonial view of history in Korea. As a scientific person who was an ideal type of the intellectual that the modern Japan required, his research method was based on direct observations and positive proof of the objects. However, his basic perspective to the Korean race was parallel with the biased view point that the Japanese intellectuals in the Meiji Japan period shared. In this context, Sekino approached cultural heritage in Korea with hypotheses for proving elements of Chinese culture in Korean cultural relics and the ancient Japanese domination in the southern Korean peninsula that the colonial government wanted to prove, and further what the people in the Japanese Empire wanted to believe.BRSekino’s inductive methodology contributed to more powerful foundations than other thinkers for objectifying the Japanese colonial domination in Korea, as he succeeded in eliminating debates on his approach to Korean cultural relics. By adopting the basic guideline of Korean archaeology and art history established by Sekio, which masks the biased view on the colonial past with the name of the scientific objectivism, Japanese scholars in colony Korea could insist that they conducted their research with objective ways. In this context, for the Imperial Japan, Sekino was a more suitable man for rationalizing its dominance to Korea than ideologists who brought about controversial issues.

Religious Perspectives on Wonosobo Coffee Farmer Community Empowerment Actors in Community Empowerment Activities

A Religion is the basis of every human life, inseparable from the life of Indonesian society. As social being’s humans can’t live alone or live in need with other human beings. Religion teaches to help each other on the cause of good, such as: the common welfare goal, altruism. Prosperity can be achieved together with the empowerment of the community commanded by an empowerment actor. Empowerment actors need to have a handle on religious values so this article discusses the relationship between the religious values of empowerment actors and the empowerment activities carried out. This article is based on field trip study activities held by the Master and Doctoral Extension Development Study Programs in Wonosobo Regency and use a qualitative approach. The data was obtained from visits and interviews with coffee farmer empowerment actor, Mr. Romadhon. Data analysis was carried out by comparing the literature review with the state of the field submitted by the informant. The results explained that as an empowerment actor, Mr. Romadhon has a handle on religious values so that in every step he has a religious basis and a good purpose for the target community. Therefore, religion can be a basic perspective in carrying out empowerment for the noble purpose of helping others towards goodness in life.

Problems of Cultural Confidence in the New Era and Countermeasures

The confidence of the nation comes from the confidence of culture, while culture is the spirit and soul of a nation, and the development of culture is related to the politics and economy of the whole country in many aspects. Taking the excellent traditional Chinese culture as the basic perspective, this paper will analyze the problems faced in developing the cultural confidence of socialism with Chinese characteristics from the basic connotation, ideological origin as well as the existing problems and the reasons of constraints, with socialism with Chinese characteristics in the new era as the background of the times, and put forward suggestions and countermeasures according to the problems. This paper adopts a combination of literature research, abstract and concrete, history and reality to start from the ideological origin of socialist cultural self-confidence with Chinese characteristics, analyze some representative outstanding traditional cultures of the Chinese nation, and combine their role in contemporary society with their significance to the cultural construction of contemporary society, and explore a socialist cultural self-confidence path with great Chinese characteristics by linking theory with practice and concrete analysis of specific problems in the context of the new era.

The Potential of Using Websites for Communication of Political Parties: The Case of Slovakia Before the 2020 Elections

Technological advances and the use of websites have become mandatory tool for any political entity trying to succeed in the competition for votes. The main objective of the study is to identify the level of effectiveness of political communication on the websites of selected political parties in Slovakia. The evaluation is based on the application of the framework for functionality and effectiveness of communication of political parties and their candidates on websites. According the framework applied, the partial objectives represent the identification of information flows on website in five different ways: from the bottom up, from the top down, horizontal, asynchronous and synchronous. A structured review of the research on the issue provides a basic perspective for identifying similarities, differences, challenges, and positives, as well as the possibility to carry out a comprehensive confrontation with the study’s findings. The analysis focuses on the environment of the Slovak Republic, looking at the example of eight selected political parties from the period of the last elections – 2020. The data collection used techniques according to the nature of the examined indicators set according to the framework. To evaluate the data, we apply basic statistical analyses with a comparative form of presentation. The findings demonstrate a medium to higher degree of effectiveness of the communication of selected political parties on the websites. The quality and scope of the information provided on websites is also currently related to the length of time in the party system, regardless length of representation in the parliament. According to study results the deficits primarily appear when providing answers to questions outside of published information, using an interactive form of content or more active cooperation with partner websites. The observed state of the selected cases demonstrates the one-way nature of the provision of information from the subject to the recipient.

Инструменты разработки стратегии организации

The article discusses the tools that are used to develop and implement strategies of organizations operating in various sectors of the economy. A balanced scorecard, which includes a strategic map and a table of activities, acts as a key tool for developing an organization's strategy. The strategic map defines the required number of prospects, goals and indicators to measure the level of achievement of goals, and the table already describes the current and target values, activities and results. Together with a balanced scorecard, it is advisable to use the methodology «goals and key results» in order to describe the intermediate results that will allow achieving the goals.
 The authors show that when developing strategic maps, it is possible to take into account ESG transformation or the specifics of work in ecosystems. To the four basic perspectives (finance, customers, business processes, training and development), an environmental perspective can be added, taking into account environmental factors in the ESG transformation concept. You can also use the perspective of partners, in the case of considering a business in the ecosystem format.
 As alternatives to a balanced scorecard, the article considers: the efficiency pyramid of K. McNair, R. Lynch and K. Cross, with which you can describe the strategy of the organization, defining financial indicators, non–financial indicators, as well as actions that take into account the external and internal environment of the organization; the EP2M model, L. Meisel's strategic maps, the prism of efficiency, taking into account 5 perspectives of the organization – satisfaction of stakeholders, strategy, processes, opportunities, as well as contribution interested parties.
 The article concludes that in order to develop a strategy, it is advisable to use the integration of the analyzed tools, depending on the scope of activity, the type of strategy, and the principles of development.

Convergent Genomic Signatures of High-Altitude Adaptation among Six Independently Evolved Mammals.

The species living in the Qinghai-Tibet Plateau provide an excellent model system for studying the relationship between molecular convergent evolution and adaptation. Distant species experiencing the same selection pressure (i.e., hypoxia, low temperature and strong ultraviolet radiation) are likely to evolve similar genetic adaptations independently. Here, we performed comparative genomics studies on six independently evolved high-altitude species. The results also showed that the convergent evolution of the six species was mainly reflected at the level of rapidly evolving genes, and the functions of these rapidly evolving genes were mainly related to hypoxia response and DNA damage repair. In addition, we found that high-altitude species had more gene family changes than their low-altitude relatives, except for the order Lagomorpha. The results also show that the convergence of the gene family contraction of high-altitude species is much greater than that of expansion, revealing a possible pattern of species in adapting to high-altitude. Furthermore, we detected a positive selection signature in four genes related to hypoxia response and ultraviolet radiation damage in these six species (FYCO1, ERBIN, SCAMP1 and CXCL10). Our study reveals that hypoxia response might play an important role in the adaptation of independently evolved species to a high-altitude environment, providing a basic perspective for further exploring the high-altitude adaptation mechanism of different related species in the future.