Abstract The Borozne Health Information Opinionnaire was used to determine the amount and kind of harmful health misconceptions believed by students in basic health information classes in four-year colleges in the state of Indiana, and whether they were affected by the following factors: age, grade level, sex, race, course background, rural or urban background, marital status, major area of academic preparation, school attended, geographic location, and religion. Findings revealed (a) the most prevalent harmful health misconceptions; (b) subject-matter areas which contained the greatest percentage of harmful health misconceptions believed by the students; and (c) the existence of significant differences between the mean harmful health misconception scores of the sex, race, marital status, grade level, major area of acadmic preparation, and course background subgroups.