Basis Of Cost Research Articles

Textile waste pyrolysis: an innovative method for petrochemicals generation for sustainable economic, technological and environmental advancement.

The disposal of wastes into landfills, which has worsened the ecosystem, has made textile waste in the third world a major environmental problem. Textile waste is an environmental hazard as it biodegrades quickly and is improperly disposed of. This research is a demonstration of the study and application of textile waste pyrolysis as an innovative method for petrochemical generation for sustainable economic, technological and environmental advancement. The researchers converted textile waste (TEXW) into petrochemicals using pyrolysis. The obtained petrochemicals were fractionated after purification and characterisation using GC-MS while the physicochemical parameters of the fractionated liquid petrochemicals were analysed using standard methods. The results of the analysis showed that the liquid oil contains: carbamate (7.69%), silicic acid (4.73%), cyclotrisiloxane (4.09%), cyclohexane (7.47%), pro-2-ynyl-E-2-methylbut-2-enote (6.24%), cyclododecanol (3.95%), undec-10-ynoic acid (3.95%), 8,8-dimethylspirol-4,6-undecane-6,10-dione (3.47%), phenol (5.95%) and 1,2,5-oxadiazol-3-amine (3.85%). The results of the physico-chemical parameters of the liquid petrochemicals ranged: relative density (0.4250-0.8528 g/cm3), absolute viscosity (0.3436-0.8788 mPas), kinematic viscosity (0.4097-3.880 mm2/s), specific gravity at 15/15 °C (0.8528-0.9556kg/m3) and flash point (15-20 °C). After blending, it was observed that a 20% v/v blend of the petrochemicals enhance the physicochemical properties of major petroleum products (PMS, kerosene, diesel). It could be concluded that the use of liquid petrochemicals for the enhancement of petroleum parameters would go a long way in alleviating basic cost associated with petroleum product production.

Type 1 Diabetes Mellitus in Movies: The Hollywood Effect

Introduction. Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases with childhood onset. Cinematic films and movies have the capability to reach populations worldwide and effect their concept of this disease. This research examined the accuracy of these movies depicting T1D from childhood into adulthood. Methods. We conducted an internet search of several databases that resulted in a list of 39 movies from 2000 to 2022 with characters that had diabetes. We ultimately assessed 13 fictional movies that dealt with management of disease, character development, access to care, and complications. Results. Movies portray severe but rare diabetes manifestations such as comas. They emphasize access to basic diabetes supplies and cost of care. Only starting in 2020, a continuous glucose monitor (CGM) and insulin pumps are shown. Female characters are presented as resilient and unaffected by the struggles of their T1D. Conclusions. This sample of fictional movies portrays extreme T1D symptoms and mostly outdated technology for monitoring and treatment. It would be beneficial if future movies reflected the advances in closed-loop CGM/insulin pumps. It is important for clinicians to be aware of how the movie industry is presenting the disease to their patients. Clinicians can use popular movies to start difficult discussions with their patients about topics pertinent to the comprehensive care of T1D.

The economics of translating a biosimilar from lab to market in India.

This study aims to establish a cost basis for biologics manufacturers and policymakers by quantifying the price and time required to bring a biosimilar from the lab to market. For efficient implementation of a cost-based policy, especially for life-saving medicines like biosimilars, it is imperative to establish a benchmark for the cost involved in biosimilar development. In this holistic and multiple-case study, stage-wise cost estimates of biosimilar development were obtained for microbial and mammalian systems. The investigation of six biopharmaceutical companies based in India concluded that biosimilar development through the microbial system costs ∼18 million USD and ∼21 million USD for the mammalian system. Additionally, 45-50 million USD is required as a one-time capital investment. Further, US/EU authorization can cost ∼25 million USD per product. Clinical studies are the most expensive and account for 60%-70% of total development cost. The presented information can serve as a basis for implementing cost-based pricing in countries like India and reimbursement policies for biosimilars under Medicare Part B in the United States.

Cost-Effectiveness of Vibrant System vs. Linaclotide in Chronic Idiopathic Constipation.

Chronic idiopathic constipation (CIC) is a common disorder that has a large unmet clinical need, affecting 8.0-12.0% of the US population and disproportionately affecting female individuals more than male individuals. Patients and physicians are equally dissatisfied with over-the-counter and prescription treatments. Physician dissatisfaction is at 78%. CIC has a significant negative impact on quality of life (QoL). The objective of this analysis was to compare the total cost and QoL of the Vibrant System vs. linaclotide, over 1-3years of treatment. Markov models were utilized to project 1-3-year US costs and health outcomes (quality adjusted life years, QALYs) comparing theVibrant System to the current standard of care pharmacologic therapy (linaclotide). One model examined direct (D) costs plus QALYs. Direct (D) costs included list price of product and medical treatment costs due to adverse events. Costs (D) were as of 2024; derived from themedical literature. A second model examined D as well as indirect (I)costs (absenteeism, presenteeism) [D + I] and QALYs. Longitudinal 12-month persistence prescription data for linaclotide was obtained from IQVIA claims data. The Vibrant System persistence data was derived from post market collection. One-way sensitivity analyses were also performed. Years1-3 direct costs were lower with Vibrant System with improved QALYs. Cumulative D + I data analysis for the Vibrant System at 12months, and for years2 and 3 show increased cost savings from $345 to $3866 with improved effectiveness. On the basis of lower costs and improved QALYs, the Vibrant System should be considered a first-line therapy for CIC and should be covered by insurers.

Reliability-based optimization for concrete-filled steel tubular columns incorporating multi-advanced techniques and model constraints

This work presents an advanced structural reliability analysis of circular concrete-filled steel tubular (CFST) members through machine learning and global optimization, together with numerical Monte Carlo simulations (MCS). The artificial neural network (ANN) model is developed and validated against available experimental data. On the basis of monetary cost of materials, the optimal design of CFST members with reliability constraint is formulated and solved by balancing composite motion optimization (BCMO) algorithm. Based on the MCS, reliability analysis is then carried out to calculate the coefficient of variation of optimal design under different loads. Subsequently, a comprehensive prediction simulation, taking account of the uncertainty of experimental data and potential errors from models (ANN, MCS, and BCMO), is performed to generate the statistics on the axial capacity of CFST members. The critical value for the optimal solution is also investigated as a function of the input variables. The results of this study can be applied to achieve a better reliability-based design optimization with minimum cost for the circular CFST columns.

Economic study of Binadhan-22 production in some selected areas of Bangladesh

This study was conducted in four districts of Bangladesh, namely Mymensingh, Bogura, Naogaon and Rangpur to estimate the profitability and factors affecting gross return of the variety. This study was based on primary data which were collected from 200 Binadhan-22 growing farmers. In the sampled areas data were collected through pre-designed interview schedule from January-February, 2023. Tabular, descriptive statistics and Cobb-Douglas production function model were used to fulfill the objectives. It was found that Binadhan-22 production is profitable. The average net return per hectare was Tk. 28876. The net return was highest in Rangpur (Tk. 32480/ha) followed by Naogaon (Tk. 28554/ha), Mymensingh (Tk. 27331/ha) and Bogura (Tk. 27139/ha), respectively. Benefit cost ratio was estimated at 1.39 and 2.04 on full cost and variable cost basis. Cobb-Douglas production function was chosen to determine the factor affecting gross return of Binadhan-22 production. All of the factors namely, human labour cost, power tiller cost, seed cost, fertilizer cost, irrigation cost, insecticides cost were statistically significant and positive. The regression coefficients for farming experience and agricultural training under all areas had negative but significant relationship at 5% and 10% level, respectively. The regression coefficient of age was positive and significant at 10% level. Under all areas, the regression coefficients of education and farm size were positive but not significant. Farmers faced some constraints in cultivating of the variety. The first ranked constraint was lack of availability of seeds (93%). Other constraints were lack of training (61%), lack of capital (38%) and lack of technical know-how (16%). In addition to helping farmers use a better combination of inputs that will create higher productivity and return, effective extension services may also assist farmers in cultivating rice in a way that will contribute to food security and self-sufficiency. Bangladesh J. Nuclear Agric, 38(1): 81-91, 2024

Farmers’ Perception and Financial Profitability of Mustard Production in Bangladesh

The study was undertaken to assess farmers’ perception and explore the factors affecting farmers’ decision to adopt mustard production along with estimate financial profitability and identify potentials and problems of mustard production. Based on stratified random sampling, 120 farmers were interviewed using a structured questionnaire to collect primary data from different villages of Ullahpara upazila under Sirajganj district of Bangladesh. A combination of descriptive statistics, mathematical and statistical technique was used to analyze the data and to achieve the objectives. The study depicts that the highest number of the respondents (35%) belong to the 31-45 age group. Seventy two percent respondents were small farmers having land less than 1.0 hectare and they allocated 34% of their farm area for mustard production. Financial profitability analysis shows that mustard production was profitable on both variable cost and total cost basis and its benefit cost ratio (BCR) was more than one. In case of farmers perception, it was revealed that short duration crop, consumers’ preferences, product price, extension services and sharing of work among household members were the main driving factors for mustard production. Applying dichotomous logistic regression model, four factors namely, farmers’ age, number of family members, experience and farm size were found as significant determinants of adoption of mustard production. Large domestic market, limited use of high-yielding varieties, growing demand for mustard oil and attack of pests and diseases were found as important strength, weakness, opportunities and threats of mustard production, respectively. Finally, the study recommends that there are ample opportunities to enhance mustard production by ensuring access to quality seeds, adopting new technologies, securing fair prices, providing input subsidies, and improving institutional credit facilities with favorable terms and conditions. Bangladesh J. Nuclear Agric, 38(1): 65-80, 2024

Calculation of the Basic Cost of Boarding Rooms Using the Activity Based Costing Method in Determining Boarding Room Rental Rates (Case Study of Boarding Houses in Environment VIII, Bahu Village)

Calculation of the Basic Cost of Boarding Rooms Using the Activity Based Costing Method in Determining Boarding Room Rental Rates (Case Study of Boarding Houses in Environment VIII, Bahu Village)

Optimization of pure elemental and oxide-based shielding materials for cost

A common aspect to shielding material research is the combination of high atomic number inclusions with binders although the costs of the inclusions will vary with chemical form and have associated density and atomic number dependencies on attenuation properties. As most metals are cheaper in their oxide forms (sometimes drastically) we considered oxide forms to substantially reduce potential cost. This study then investigates the combined shielding and cost optimization of pure elemental and oxide-based shielding materials as well as steel, water and concrete. This focus on shielding effectiveness per cost and weight basis also incorporates contributions from scattered radiation in the form of radiation buildup for these comprehensive materials. In this sense, we define a new metric which incorporates cost, weight and scatter radiation for assessing shielding material attractiveness. We used MicroShield to calculate the shielding ability of each material. Our findings revealed that water, concrete, and lead demonstrated superior performance in terms of cost-effectiveness. This research contributes to the understanding of affordable and efficient shielding materials and has implications for industries reliant on radiation protection, such as nuclear power generation, medical imaging, and space exploration.

Financial and Operational Training for Culinary Businesses at the GKI Pamulang

Starting a business is challenging, particularly when it comes to sustaining it. Some members of the GKI Pamulang congregation already run businesses but need growth due to stagnant or declining income. Additionally, there are congregation members who are employees interested in launching a culinary business and need guidance on getting started. The goals of this community service initiative are: (1) to provide an overview of the culinary business, (2) to inspire GKI Pamulang members to either start a culinary venture or sustain their existing businesses, and (3) to offer training on financial management (including basic financial reports, cost calculation, and taxation) and operations for culinary businesses. The activity employs lectures, case studies, presentations, and mentoring as methods. Held on May 25, 2024, at GKI Pamulang, the event was attended by 29 congregation members. Participants expressed satisfaction with the relevant material presented and gained valuable insights and motivation for starting and maintaining a culinary business, as well as knowledge on financial management and business operations.

Residential mobility for young adults in extended foster care

BackgroundPlacement stability is tied to well-being among children living in foster care, yet residential mobility remains largely unexplored for transition-age youth residing in extended foster care (EFC) between ages 18 and 21. During the time young adults in EFC can remain in foster homes, child welfare agencies offer living arrangements tailored to the transition into adulthood. In supervised independent living placements (SILPs), residents receive monthly stipends to cover their housing expenses and are responsible for covering food, utilities, and other basic needs-related costs. Transitional housing placements (THPs) offer light-touch caregiving during the transition to independence to ensure that residents have their basic needs met. ObjectiveThe current study is the first comprehensive examination of factors associated with residential mobility in a statewide population of young adults residing in EFC. ParticipantsUsing California administrative Child Protective Services records, we identified young adults who turned 18 between 2016 and 2019 and lived in care for at least 1 week (N = 10,517). MethodsNegative binomial regression evaluated the association between residential characteristics and per-year EFC moves. ResultsWe found that young adults had a median number of 1.0 moves during EFC, with a median rate of 0.67 moves per year in EFC (i.e. roughly one move every 18 months). SILPs and THPs were the most common primary residence types among the study population (41.6 % and 26.0 %, respectively). The average duration of stay in EFC was two years, which varied by primary residence type. Regression results showed that predominant residence type in EFC was associated with EFC mobility, with young adults in SILPs being more likely to experience slightly higher mobility than those primarily living in other residence types (0.82 versus 0.75 moves per year in EFC). ConclusionsFindings suggest that housing for EFC residents tends to be long-lasting and relatively stable in California. Modest variations in mobility by residential type and by experiences in foster care before age 18 underscore the importance of integrating housing and psychosocial resources during independent living planning processes. The commonality of out-of-county residence should be considered when determining housing and transportation expenses for residents, given its potential implications for access to medical and behavioral health care, academic institutions, and employment opportunities for young adults receiving EFC services.

Research Article: Profitability of Producing Early Generation Rice Seed Under Pawe Districts: Northwestern Ethiopia

This research was conducted on the profitability of producing early-generation rice seeds under pawe districts in northwestern parts of Ethiopia. Early-generation seed production is a promising business that can be a solution to increase rice productivity and farmers' income. However, limited technology use, soil preference of commodity, and limited rice seed multiplier companies and human resources often become obstacles to addressing improved seed for farmers, especially smallholder farmers. The main purpose of early-generation seed production is to maintain the genetic potential and identity of a variety and regular provision of high-quality breeder seed which is the basis for subsequent seed production. Variety maintenance, production, and distribution of the breeder, pre-basic, and basic seed are carried out by the public breeding institutions or private seed sector. Samples were taken from rice seed farmers within two production seasons. This research aims to understand the economics of current seed production in the case of rice crops and provide basic information cost structure of EGS production for private and public enterprises. The analysis carried out includes cost analysis, income, and profitability analysis. The results showed that rice seed farmers were profitable with a 1.381 benefit-cost ratio and 27.58 profit margins. The total profit of one-hectare pre-basic seed production of rice was 47,433.565 which is the difference between total revenue (Price*Quantity =171939.39) and total cost (124,505.825).

Process Selection on the Basis of Time Cost and Quality for Development Components of Aluminium Bracket

Development of various new processes has reduced the development of tooling while Designing of Aluminium Component before going to mass production by Dies. The selection of the Process to manufacture Proto quality of Aluminium is not significant. In present research is an attempt to prove that Die Casting Die in soft condition die is also recommended process for commissioning quantity of aluminium component because for prototyping one or two quantity are sufficient. Proto DCD process is also Compared with Time, Cost & quality parameters on this basis process can be selected only for maximum one thousand quantity requirement

Development of basic cost standards for the provision of public services by regional laboratory and diagnostic institutions

Development of basic cost standards for the provision of public services by regional laboratory and diagnostic institutions

Machine Learning Method for Forecasting Wind Power Using Continuous Wind Speed Data

Among various nonconventional energy sources, wind energy is a noteworthy and suitable source with the ability to generate electricity continuously and sustainably. However, there are a number of drawbacks to wind energy, including high basic utilization costs, the static nature of wind farms, and the challenge of locating energy that is wind-efficient. regions. Using five machine learning methods, long-term wind power prediction was done in this study using daily wind speed data. We suggested an effective way to forecast wind power values using machine learning techniques. To demonstrate how machine learning algorithms, perform, we carried out a number of case studies. The outcomes demonstrated that long-term wind power values might be predicted using machine learning algorithms in relation to past wind speed data. Additionally, the consequences show that machine learning-based Models could be used in places other than those where they were taught. This study showed that, by employing a model of a base site, machine learning algorithms could be applied frequently prior to the development of wind plants in an undisclosed environmental region, provided that it makes sense.

From Bioreactor to Bulk Rheology: Achieving Scalable Production of Highly Concentrated Circular DNA.

DNA serves as a model system in polymer physics due to its ability to be obtained as a uniform polymer with controllable topology and nonequilibrium behavior. Currently, a major obstacle in the widespread adoption of DNA is obtaining it on a scale and cost basis that accommodates bulk rheology and high-throughput screening. To address this, recent advancements in bioreactor-based plasmid DNA production is coupled with anion exchange chromatography producing a unified approach to generating gram-scale quantities of monodisperse DNA. With this method, 1.1 grams of DNA is obtained per batch to generate solutions with concentrations up to 116mg mL-1. This solution of uniform supercoiled and relaxed circular plasmid DNA, is roughly 69 times greater than the overlap concentration. The utility of this method is demonstrated by performing bulk rheology measurements at sample volumes up to 1 mL on DNA of different lengths, topologies, and concentrations. The measured elastic moduli are orders of magnitude larger than those previously reported for DNA and allowed for the construction of a time-concentration superposition curve that spans 12 decades of frequency. Ultimately, these results can provide important insights into the dynamics of ring polymers and the nature of highly condensed DNA dynamics.

EXPLORING THE IMPACT OF A COLLEGE INTERNSHIP PORTAL ON STUDENT

Abstract: The internship program provides an excellent opportunity for budding scholars to familiarize themselves with the process of formulation of foreign policy and its implementation by the Government. Interns shall report to and work under close supervision of the concerned Head of Division (HOD). They may be required to conduct research, write reports, analyze evolving developments, or carry out any other task entrusted to them by the HOD. An honorarium of INR 10,000 per month will be paid to each intern to defray basic costs. Cost of one-time to and fro air travel subject to a ceiling of the prevailing economy class air fare between the State capital and Delhi, from the domicile State or from the college / university of the selected candidates will be provided. The interns would be responsible for their board and lodging in Delhi during the period of their internship.Every student is individually responsible for finding an internship. This implies actively seeking such a placement and directly contacting the organizations that you are interested in. We advise students to start searching for internship early on, as there may be early deadlines for some of the most attractive places. Internship ads are found in the university portal. It is allowed to receive payment from the internship organization. When contacting organization. you have the option of using our introductory letter presenting the master’s program . Please download and complete with your details before sending it to the student officefor signature. The letter of introduction may be used as a complement to the CV and personal letter that you send to potential internship organizations. KEYWORDS: HTML, CSS, Javascript, Bootsrap, C# , SQL SERVERIntroduction

Cost-effectiveness of newborn screening for sickle cell disease: a systematic review protocol.

The purpose of this systematic review is to assess the cost-effectiveness of targeted/selective newborn screening compared with universal screening for sickle cell disease across various countries and settings. The incidence of sickle cell disease is a widespread and potentially fatal hematologic disorder that affects thousands of newborns worldwide. The cost of newborn screening creates a burden on households and the economy. Studies will be eligible for inclusion in the review if they focus on the cost-effectiveness of newborn screening for sickle cell disease, comparing targeted/selective screening with universal screening. A preliminary search of MEDLINE (PubMed) was undertaken using MeSH terms, such as sickle cell disease, newborn , and economic evaluations . Two reviewers will screen the titles, abstracts, and full text independently against the inclusion criteria. Disagreements will be resolved by discussion or with a third reviewer. To assess methodological quality, the JBI checklist for economic evaluation will be used. Data will be extracted by 2 reviewers using a modified JBI data extraction form. The JBI dominance ranking matrix for economic evaluations will be used to summarize and compare the results. Cost-effectiveness will be measured on the basis of cost per test/case detected, quality-adjusted life years gained, or disability-adjusted life years averted. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) assessment will be conducted to evaluate the certainty of economic evidence, such as use of resources and expenditures, and to incorporate the results into the decision-making process. PROSPERO CRD42017057963.

Performance test and economic analysis of paddy direct seed planter modified pulled by tractor (amator) in tidal swamp, South Sumatra

Abstract Lack of labor is another obstacle to the characteristics of the tidal swamp land itself so that the use of agricultural equipment and machinery such as Amator can be used as solution. This paper aims to analyze the use of the amator in terms of technical and economic aspects of the equipment so that it is known whether it is efficient and profitable for farmers. Data collection was carried out through observation of equipment performance tests in the field and key informant interviews. This research was carried out in Sri Katon Village, Air Salek District, Banyuasin Regency. The data observed are technical performance including work capacity and work efficiency, as well as economic analysis in the form of basic costs and break-even point of using equipment. The results of the performance test show that the amator has a high efficiency (87.52%) with an effective working capacity value of 0.6244 ha hr−1 (1.6012 hr ha−1). The basic cost incurred for the use of the amator is IDR 193.145 ha−1 with a BEP of 16,8 ha yr−1. The use of amator with seeds only 35 kg ha−1 can save planting costs of IDR 200,000 ha−1 compared to the farmer practice.

Deployment of Lifetime Cost Analysis to Reassess Economic Current Density in the Presence of Vietnam’s Market Economy

A decent choice of conductor size for overhead power transmission lines can provide economic advantages throughout the project’s lifetime. One of the crucial criteria for sizing conductors is economic current density. In Vietnam, the electricity industry has extensively utilized the 1950s-era economic current density that ignores the value of cash flow at diverse points in time and applies the assumption of the constant electricity tariff and wire cost. These costs, nonetheless, are likely to greatly impact the figures of economic current density; as a result, these figures must be modified. This paper puts forward novel figures of economic current density that are systematically determined on the basis of lifetime cost (LTC) analysis in the presence of Vietnam’s market economy. The LTC is made up of the initial capital expenditure (ICE) and the overall operating cost (OPC), which includes the expense incurred for maintenance and electricity energy loss. An analytical formulation of ICE related to conductor size and system voltage is established based on information from recently built overhead transmission lines and a regression-based method. The electricity energy loss is computed based on equivalent hours of maximum power loss contingent upon equivalent hours of maximum power usage throughout an analytical expression obtained on the basis of the regression technique from load consumption patterns in the past. Finally, the feasibility and efficacy of the proposed economic current density values are validated by practical case studies of overhead transmission lines in Vietnam. The deployment of the suggested strategy demonstrates a decrease in lifetime cost ranging from approximately 5% to around 20% in comparison to the methodology prescribed by the existing Vietnam standard.