This study aimed at assessing groundwater potential in Misau and Dambam areas of Bauchi State, Nigeria. Vertical Electrical Sounding (VES) survey was also conducted to carry out the study. Five thematic maps were generated for weighted overlay. Descriptive statistics was used to analysed data on water supply situation, aquifer parameters were analysed using standard table where porosity and permeability were calculated. The VES data was analysed using ipi2win, thematic maps were produced through overlay analysis using extension of ArcGIS 10.4. VES result reveals the existence of about three to four geologic layers in the study area which constitute the topsoil, weathered rock, weathered/fractured rock, fractured basement, and fresh basement rock. Nine out of the thirteen soundings conducted were found to be of good in nature while the only non-promising aquifers were found in Jalam Kukadi, Hardawa PHC, Bada Koshi, Dambam A Bam. Five groundwater potential zones were determined which are very low 354 km2 (15%), low 393 km2 (15%), moderate 416 km2 (20%), high 436 km2 (25%), and very high 497 km2 (25%). Drainage is the most important factor affecting groundwater occurrence with 25% which is the highest followed by geology with 22%. It can be concluded that 50% of the study area was characterized under high, and very high groundwater potential. It is recommended that areas with poor groundwater potentials government and non-governmental organizations should provide them with an alternative source of water to aid them during periods of difficulties.