Basal Cell Carcinoma Arising Research Articles

Multiple Foci of Basal Cell Carcinoma Arising in Rhinophyma: A Case Report and Literature Review

Rhinophyma is a benign condition caused by the excessive growth of sebaceous glands in the nasal tissue, presenting with symptoms such as nasal hypertrophy, erythema, and papules. Cases of basal cell carcinoma in rhinophyma have been reported in literature, but its etiological role remains unclear. It is uncertain whether rhinophyma is predisposed to neoplasm development or if their coexistence is coincidental. We conducted a literature survey to identify such cases reported over the years. We identified 22 studies reporting a total of 47 cases in the literature, all involving male patients. The most common pattern of occurrence was the rapid growth of a nodular formation within the context of rhinophyma. The elucidation of the association between basal cell carcinoma and rhinophyma remains challenging. The presence of multiple foci supports the theory that rhinophyma may play a role in their development, but larger studies are needed to establish a causal relationship.

熱傷瘢痕から発症した基底細胞癌の 1 例

熱傷瘢痕から発症した基底細胞癌の 1 例

Cutaneous Basal Cell Carcinoma Arising in Odontogenic Cutaneous Fistula.

An odontogenic cutaneous fistula is a pathological communication between the outer skin surface of the face and the oral cavity. Facial cutaneous fistula is a complication of odontogenic infection that is often misdiagnosed with skin infection. We report a rare case, which was diagnosed as basal cell carcinoma based on the biopsy of skin lesions in the patient who had been diagnosed with odontogenic cutaneous fistula. A 64-year-old male patient presented with a cutaneous odontogenic fistula. The patient had undergone surgical extraction of fistula tract and loose tooth before dermatology or plastic surgery consultation. With the biopsy and computed tomography, it was confirmed that fistula and basal cell carcinoma. However, the connection between the fistula and skin cancer was not clear. Positron emission tomography-computed tomography scan was performed and was not detected as other local or distant metastasis. After that, wide excision of the skin lesion was performed. Although skin cancer is not commonly observed, it is necessary to rule out this disease entity by performing biopsy of skin lesions.

Basal Cell Carcinoma Arising in a Seborrheic Keratosis on the Lower Leg

Basal Cell Carcinoma Arising in a Seborrheic Keratosis on the Lower Leg

Nodular Basal Cell Carcinoma Arising in a Split-Thickness Skin Graft of the Scalp

We present the first known case of basal cell carcinoma arising in a split-thickness skin graft in the United States. The apparent low incidence of basal cell carcinoma in split-thickness skin graft attests to its unique environment and could possibly be attributed to the following: (1) the donor sites for split-thickness skin grafts are usually areas that are not subjected to heavy sun exposure; (2) individuals with skin grafts may not live as long on average, or their skin grafts may be subsequently excised with further reconstructive procedures; and (3) cases may be underreported. Because basal cell carcinomas have a fairly benign course, many patients either do not present to a physician or are not reported. This case shows that a split-thickness skin graft can have an adequate microenvironment for the development of basal cell carcinoma.

Basal Cell Carcinoma, Syringocystadenoma Papilliferum, Trichilemmoma, and Sebaceoma Arising Within a Nevus Sebaceus Associated with Pigmented Nevi

Basal Cell Carcinoma, Syringocystadenoma Papilliferum, Trichilemmoma, and Sebaceoma Arising Within a Nevus Sebaceus Associated with Pigmented Nevi

Large Superficial Basal Cell Carcinoma Arising in the Scalp

Superficial basal cell carcinoma (sBCC), a rare sub-type of basal cell carcinoma, can frequently occur in younger patients. This cancer type preferentially develops on the trunk. However, other subtypes of BCC can occur in the head and neck, probably secondary to sunlight exposure. Especially, sBCC on the scalp has been rarely-reported, accounting for 0.7~0.8% of all sBCC cases. We report a case of 71-year-old female with a large sBCC of the scalp, an unusual site of sBCC.

Basal Cell Carcinoma Arising in a Nevus Sebaceus in a Child with Facial Trichoepitheliomas

Nevus sebaceus (NS) is a congenital skin hamartoma that presents in childhood. Tumors may arise within these lesions over time. Mutations in the PTCH gene have been associated with both NS and some of the developing tumors. Only nine documented cases of basal cell carcinoma arising in nevus sebaceus in childhood are available. We present a case of an 8-year-old male with nevus sebaceus who developed a basal cell carcinoma. Evaluation for constitutional PTCH gene mutation and loss of heterozygosity (LOH) from the BCC within the NS did not reveal an underlying mutation. We further discuss the literature regarding prophylactic excision of NS.

Basal Cell Carcinoma Arising in a Tattooed Eyebrow

Malignant skin tumors, including squamous cell carcinoma and malignant melanoma, have occurred in tattoos. Seven documented cases of basal cell carcinoma associated with tattoos have also been reported in the medical literature. We encountered a patient with basal cell carcinoma in a tattooed eyebrow. We report on this case as the eighth reported case of a patient with basal cell carcinoma arising in a tattooed area.

A Case of Basal Cell Carcinoma Arising in Bilateral Mastoidectomy Scars

A Case of Basal Cell Carcinoma Arising in Bilateral Mastoidectomy Scars

A Case of Basal Cell Carcinoma Arising in Bilateral Mastoidectomy Scars

A Case of Basal Cell Carcinoma Arising in Bilateral Mastoidectomy Scars

Basal Cell Carcinoma Arising in Nevus Sebaceous during Childhood

Nevus sebaceous usually occurs as a solitary lesion located mostly on the scalp and the face. The potential for nevus sebaceous to develop malignancy is well recognized, though it is generally thought that this transformation occurs only postpubertally or later. However, few cases of basal cell carcinoma arising in nevus sebaceous before puberty were reported. Herein, we report a case of basal cell carcinoma arising in a nevus sebaceous on the scalp of a 10-year-old boy, and a review of the literature on prepubertal cases and the need for prophylactic surgery.

Use of Mohs Micrographic Surgery to Treat Basal Cell Carcinoma Arising in a Nevus Sebaceous in an African American Patient

Use of Mohs Micrographic Surgery to Treat Basal Cell Carcinoma Arising in a Nevus Sebaceous in an African American Patient

Invited Discussion: A Report of Twelve Cases of Basal Cell Carcinoma Arising in Lesions Following Laser Therapy

Invited Discussion: A Report of Twelve Cases of Basal Cell Carcinoma Arising in Lesions Following Laser Therapy

A Report of 12 Cases of Basal Cell Carcinoma Arising in Lesions Following Laser Therapy

Since the latter half of the 1990s, laser treatment has become a common practice in Korea. A group of patients diagnosed as having basal cell carcinoma (BCC) also had a history of prior laser therapy performed on undiagnosed cutaneous lesions. Clinical and histologic evaluations of these cases were performed retrospectively. Among the 138 patients who were diagnosed with BCC from 1997 to 2001, 12 lesions (8.7%, 3 males and 9 females) developed following previous laser treatment to remove undiagnosed lesions. The mean age of the patients was 55.6 years, which was younger than that of the general Korean population (62.7 years), and their noses were the most common site of lesion development. The lesions had disappeared grossly after laser therapy for 6 patients, but for the other 6 patients, their lesions had persisted or grown. The interval between the time of laser therapy and diagnosis of BCC ranged from 1 month to 3 years. The average interval was 18 months. Histologically, aggressive forms were more common in these cases as compared with the usual patterns of BCCs. Although we do not think that laser therapy causes the development of BCC directly, laser therapy does not seem to be adequate for undiagnosed lesions. And our conclusion is that the cutaneous lesions should be biopsied and thoroughly diagnosed and managed prior to laser therapy.

Basal Cell Carcinoma Arising in a Port-Wine Stain

Basal Cell Carcinoma Arising in a Port-Wine Stain

A Case of Basal Cell Carcinoma Arising in Linear Porokeratosis

A Case of Basal Cell Carcinoma Arising in Linear Porokeratosis

Basal Cell Carcinoma Arising in a Cleft Lip Repair Scar

Basal Cell Carcinoma Arising in a Cleft Lip Repair Scar

Basal Cell Carcinoma Arising in a Localized Linear Verrucous Epidermal Naevus

Basal Cell Carcinoma Arising in a Localized Linear Verrucous Epidermal Naevus

Basal Cell Carcinoma Arising in a Surgical Scar: Reconstructive Surgical Treatment

Basal Cell Carcinoma Arising in a Surgical Scar: Reconstructive Surgical Treatment