Bariatric Surgery Weight Research Articles

Physical exercise and loss of weight and body mass index in bariatric surgery: a systematic review

Introduction: bariatric surgery is considered successful when the percentage of weight loss is equal to or higher than 25 %, or when the percentage loss of body mass index occurs above 50 % long-term. Objective: to analyze the effect of physical exercise on body weight and body mass index before and/or after bariatric surgery. Methodology: articles registered in the PudMed, Scopus and Web of Science databases were searched for original papers with open access in English and Spanish that compared one or more physical exercise programs as treatment before and/or after bariatric surgery, with results on initial and final weight and body mass index, muscle mass, and fat mass from January to April 2021. Results: a total of 730 articles were obtained in the different databases and only 7 were selected for the analysis. Aerobic exercise combined with resistance training showed a greater decrease in the percentage of weight loss (% PP) and the percentage of loss of body mass index (% PBMI). Conclusions: aerobic physical exercise in combination with endurance training is the most applied program in subjects with bariatric surgery, and the most important effects are an increase in percentage of weight loss and a decrease in body mass index.

Bariatric surgery versus community weight management intervention for the treatment of idiopathic intracranial hypertension (IIH:WT): a randomized controlled trial

Bariatric surgery versus community weight management intervention for the treatment of idiopathic intracranial hypertension (IIH:WT): a randomized controlled trial

The Effect of Bariatric Surgery and Non-Surgical Weight Loss in Pre- and Post-Kidney Transplant Patients

The Effect of Bariatric Surgery and Non-Surgical Weight Loss in Pre- and Post-Kidney Transplant Patients

Successful weight loss after bariatric surgery in Appalachian state regardless of food access ranking score.

Following bariatric surgery, an explicit dietary regimen is required to facilitate and maintain successful weight loss. Without adequate access to healthy foods, weight maintenance can be hindered. Examine influence degree of food access has on Appalachian bariatric surgery patient weight loss outcomes. Appalachian University hospital, United States. A retrospective chart review was used to examine the influence of food accessibility on weight loss outcomes in an Appalachian bariatric surgery patient population at a large tertiary hospital in West Virginia between 2013 and 2017. Demographic characteristics, health and family history, and 1-year surgery outcomes were collected. A state-specific food accessibility score was calculated for each patient address using the geographic information system. Patients were assigned a food access ranking score (FARS) between 0 (low food access) and 4 (high food access) based on criteria of quantity, quality, income, and vehicle access. Patients (n = 369) were predominately married (60.5%), white (92.4%), female (77.8%), and underwent laparoscopic Roux-en-Y gastric bypass surgery (75.9%), with a mean age of 45 years. Most patients had low FARS (M = 1.67 ± .73; 72.6%). Nonwhite patients (P = .03) with a preoperative diagnosis of depression (P = .02) or without a family history of obesity (P = .01) were found to be in the lower FARS categories. FARS was not indicative of weight loss post surgery (P > .05). Food accessibility in West Virginia was not associated with bariatric surgery weight outcomes at 1-year post operation. Lower food access was associated with nonwhite race/ethnicity, diagnosed depression at baseline, and no family history of obesity. Future studies should include moreextended follow-up data collection and mixed-method approaches to capture perceptions of food access and its impact on the patients' postoperative journey.

The Association Between Adverse Childhood Experiences (ACEs) and Postoperative Bariatric Surgery Weight Loss Outcomes.

Previous research demonstrates that exposure to adverse childhood experiences (ACEs) is associated with development of obesity. The same mechanisms mediating this relationship could theoretically affect attempts to lose weight in adulthood. However, it is unclear whether or not exposure to ACEs impacts the effectiveness of bariatric surgery. The present study aimed to examine the association of exposure to ACEs to postoperative weight loss outcomes. One hundred ninety-eight patients undergoing bariatric surgery were evaluated for their exposure to ACEs, determined by a presurgical questionnaire and recorded as an ACEs score. Percent total weight loss (%TWL) was calculated to evaluate postoperative weight loss at 1-, 3-, and 6-month intervals postoperatively. One hundred forty-two participants were available for follow-up at the 6-month postoperative interval. The sample consisted of 167 women and 31 men with a mean age of 47.7. Twenty-five percent of participants experienced high exposure to ACEs, defined as experiencing ≥ 4 ACEs. The average %TWL at 6months was 16.52%. Multilevel modeling found no significant relationship between ACEs score and %TWL at any of the postoperative time intervals, both before and after adjusting for age, sex, and race. High exposure to ACEs was not associated with poorer weight loss outcomes, and participants with a large number of ACEs generally lost the anticipated amount of weight.

A400 Bariatric Surgery Weight Loss Success and Mental Health Symptomatic Improvement

Patients undergoing bariatric surgery have high rates of psycopathology than the general population. The relationship between mental health and bariatric surgery is not well understood. Determine the association of self-reported postoperative improvement in anxiety and depression symptoms with 1) Postoperative weight loss success (PWLS) (defined as >50% excess weight loss) and 2) Self-reported satisfaction, in patients who were diagnosed with anxiety or depression prior to undergoing Sleeve Gastrectomy (SG) or Roux-en-Y Gastric Bypass (RYGB).

Association of intracellular lipid accumulation in subcutaneous adipocyte precursors and plasma adipokines in bariatric surgery candidates

BackgroundThe adipocyte expansion is a critical process with implications in the pathogenesis of obesity associated metabolic syndrome. Impaired adipogenesis leads to dysfunctional, hypertrophic adipocytes, local inflammation and peripheric insulin resistance.MethodsWe assessed the relationship between the adipogenic differentiation capacity of the subcutaneous adipose derived stem cells (ASCs), evaluated by total lipid accumulation, and the metabolic and hormonal profile in a group of obese female patients proposed for bariatric surgery (N = 20) versus normal weight female controls (N = 7).ResultsThe lipid accumulation (measured as optical density at 492 nm) of ASCs during their differentiation to adipocytes was significantly lower in ASCs isolated from obese patients as compared to ASCs isolated from normal weight patients (0.49 ± 0.1 vs. 0.71 ± 0.1, p < 0.001). Significant negative correlations between lipid accumulation in adipogenic differentiated ASCs and plasma concentrations of triglycerides (p < 0.01), insulin (p < 0.001), HOMA-IR (p < 0.01), adiponectin (p < 0.05) and leptin/adiponectin ratio (p < 0.05) were found in obese group.ConclusionsIn severely obese female patients, the abnormal adipogenesis is related to insulin resistance and leptin/adiponectin ratio. The abnormal lipid accumulation in the mature adipocyte derived from obese ASCs could possible predict the further development of type 2 diabetes mellitus in severely obese patients and influence the selection of patients for bariatric surgery.

Motivations of Men with Severe Obesity Who Pursue Bariatric Surgery or Medical Weight Management

Motivations of Men with Severe Obesity Who Pursue Bariatric Surgery or Medical Weight Management

Food cravings and body weight: a conditioning response.

To provide current information on interventions that alter food cravings. Specifically, dietary, physical activity, pharmacologic, and bariatric surgery interventions are examined. Lastly, the effects of social determinants and current controversies on food cravings are outlined. Dietary, pharmacologic, and bariatric surgery weight loss interventions decrease food cravings. Physical activity interventions also decrease cravings. There is potential to see differential responses in food cravings in different demographic and socioeconomic groups, but more research is needed. Food cravings influence body weight. Food craving reductions are because of reductions in the frequency of consuming craved foods, independent of energy content, but further research is warranted. Most findings continue to support the conditioning model of food cravings.

OSA anatomic risk factors and bariatric surgery weight loss: a pilot magnetic resonance imaging study

OSA anatomic risk factors and bariatric surgery weight loss: a pilot magnetic resonance imaging study

Highlights from the Diabetes UK Professional Conference 2018

Highlights from the Diabetes UK Professional Conference 2018

Further psychometric validation of the BODY-Q: ability to detect change following bariatric surgery weight gain and loss

BackgroundRecent systematic reviews have identified that current patient-reported outcome instruments have content limitations when used to measure change following bariatric surgery. The aim of this study was to measure change after bariatric surgery using the BODY-Q, a PRO instrument designed for weight loss and body contouring.MethodsThe BODY-Q is composed of 18 independently functioning scales and an obesity-specific symptom checklist that measure appearance, health-related quality of life (HR-QOL) and experience of health-care. The sample for this study included patients who were exploring or seeking bariatric surgery in Hamilton (Canada) at the time of the BODY-Q field-test study and who agreed to further contact from the research team. These patients were invited to complete 12 BODY-Q scales and the symptom checklist between 7 June 2016 and 29 November 2016. Data were collected online (REDCap) and via postal surveys. Clinical change was measured using paired t-tests with effect sizes and standardized response means.ResultsThe survey was completed by 58 of 89 (65%) pre-bariatric participants from the original BODY-Q field-test sample. The non-participants did not differ from participants in terms of age, gender, ethnicity, BMI or initial BODY-Q scale scores. Participants who had undergone bariatric surgery had a mean BMI of 49 (SD = 7) at time 1 and 35 (SD = 7) at time 2. Time since bariatric surgery was on average 2 years (SD = 0.5) (range 0.4 to 3 years). Percentage total weight loss ranged from 12 to 51 (mean 31, SD = 9). The difference in the proportion of patients to report an obesity-specific symptom on the BODY-Q checklist was significantly lower at follow-up for 5 of 10 symptoms. Participants improved on BODY-Q scales measuring appearance (of abdomen, back, body, buttocks, hips/outer thighs, inner thigh), body image and physical function (p < 0.001 on paired t-tests) and social function (p = 0.002 on paired t-test). These changes were associated with moderate to large effect sizes (0.60 to 2.29) and standardized response means (0.47 to 1.35).ConclusionsThe BODY-Q provides a set of independently functioning scales that measure issues important to patients who undergo weight loss. BODY-Q scales were responsive to measuring clinical change associated with weight loss 2 years after bariatric surgery.

Sugammadex by ideal body weight versus 20% and 40% corrected weight in bariatric surgery – double-blind randomized clinical trial

Background and objectivesThe weight parameters for use of sugammadex in morbidly obese patients still need to be defined. MethodsA prospective clinical trial was conducted with sixty participants with body mass index≥40kg.m−2 during bariatric surgery, randomized into three groups: ideal weight (IW), 20% corrected body weight (CW20) and 40% corrected body weight (CW40). All patients received total intravenous anesthesia. Rocuronium was administered at dose of 0.6mg.kg−1 of Ideal weight for tracheal intubation, followed by infusion of 0.3–0.6mg.kg−1.h−1. Train of four (TOF) was used to monitor depth of blockade. After spontaneous recovery TOF-count 2 at the end of surgery, 2mg.kg−1 of sugammadex was administered. Primary outcome was neuromuscular blockade reversal time to TOF≥0.9. Secondary outcome was the occurrence of postoperative residual curarization in post-anesthesia recovery room, searching the patient's ability to pass from the surgical bed to the transport, adequacy of oxygenation, respiratory pattern, ability to swallow saliva and clarity of vision. ResultsGroups were homogenous in gender, age, total body weight, ideal body weight, body mass index, type and time of surgery. The reversal times (s) were (mean±standard deviation) 225.2±81.2, 173.9±86.8 and 174.1±74.9 respectively, in the IW, CW20 and CW40 groups (p=0.087). ConclusionsNo differences were observed between groups with neuromuscular blockade reversal time and frequency of postoperative residual curarization. We concluded that ideal body weight can be used to calculate sugammadex dose to reverse moderate neuromuscular blockade in morbidly obese patients.

A5265 - Do Surgical Complications Affect Bariatric Surgery Weight Loss Outcomes?

A5265 - Do Surgical Complications Affect Bariatric Surgery Weight Loss Outcomes?

Endometrial cancer prevention - does bariatric surgery play a role?

Once obesity became a global health problem, the incidence of various malignancies reported a significant increase, leading to the hypothesis that a certain correlation might exist. This correlation was evident especially in hormonally dependent tumors such as endometrial cancer and breast cancer. In consequence, attention was focused on determining whether bariatric surgery weight loss induction might play a protective role.

Early post-operative psychosocial and weight predictors of later outcome in bariatric surgery: a systematic literature review.

This is the first systematic review to synthesize the evidence concerning early post-operative variables predictive of later weight and psychosocial outcomes in bariatric surgery. Eight electronic databases for empirical studies were searched (1954 to 2016). Most of the 39 included studies reported solely on weight outcomes; eating and psychosocial outcomes were less common. A better early weight loss trajectory was the most consistent predictor of more successful medium-term weight outcome (≤24months); however, its relationship to longer term weight loss maintenance is less certain. Early eating adaptation may be associated with later weight loss, but further research is needed. Evidence is lacking for associations between early adherence or early psychosocial variables and later outcome. In particular, the relationship between early post-operative depression and later weight remains unclear. Little research has considered early prediction of later eating or psychosocial outcomes. Consideration of mediating or moderating relationships is lacking. The body of evidence is limited, and synthesis is hampered by heterogeneity in the type and time at which predictors and outcomes are measured and quality of statistical reporting. Further research on prospective prediction of bariatric surgery outcome is needed to guide early post-operative intervention for those at greatest risk of poor outcomes.

Continuous surveillance of oxygen saturation and respirations after bariatric surgery

Background: Continuous, post-operative patient monitoring can provide healthcare workers with earlier warning signs of patient deterioration. The Masimo Pulse CO-Oximeter (Masimo Corporation, Irvine, CA) has acoustic monitoring technology which measures respiratory rate (RR) by analyzing acoustic signals generated across the upper airway while breathing. We continuously monitored for 19-24 hours (hrs) post-surgery RR and oxygen saturation (SpO2) in obese patients who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) for bariatric surgery weight loss. The objective was to assess incidence of decreased RR ( 30, between 30 and 10, and < 10 breaths per minute). The percentage of time that the patient spent in each range was calculated. Median values were calculated for each category. Results: During the extended monitoring period, the median percentage of time spent with SpO2 below 90% was 5.4%. The median percentage of time that a subject had a RR of less than 10 respirations/min was 0%. There was no correlation between SpO2 and respiratory rate. Fourteen patients in our study population were on continuous positive airway pressure (CPAP) and reported VAS scores between 3 and 6. This may have prevented them from being deeply sedated. There were no apnea periods longer than 30 seconds. Conclusions: In this small group of obese patients, a low RR was not encountered during an extended post-operative period. These patients did not experience desaturation, apnea, or significant reductions of RR.

Su1982 Compliance With Bariatric Surgery Follow-Up and Weight Loss Outcomes

Su1982 Compliance With Bariatric Surgery Follow-Up and Weight Loss Outcomes

Doctor, How Much Weight Will I Lose?-a New Individualized Predictive Model for Weight Loss.

Bariatric surgery is an effective treatment for weight loss, but the patient's ability to reach a sustained weight loss depends upon several technical and individual factors. Creating an easy model that adapts bariatric surgery's weight loss goals for each patient is very important for pre-surgery and follow-up evaluations.

Abstract 18541: Gastric Bypass Surgery is Associated with a Marked Reduction in Circulating High Sensitivity Cardiac Troponin I Concentrations: Comparison with Intensive Lifestyle Intervention

Introduction: Morbid obesity is associated with increased cardiac mass and cardiovascular risk. Circulating high sensitivity cardiac troponin I (hs-TnI) concentrations reflect cardiac mass and hemodynamic stress and are strongly predictive of subsequent risk of heart failure and premature death. The impact of weight loss induced by gastric bypass surgery (GBS) and intensive lifestyle intervention (ILI) on circulating hs-TnI is unknown. Hypothesis: Weight loss induced by GBS and ILI is associated with reduced circulating hs-TnI concentrations. Methods: The Morbid Obesity treatment, Bariatric surgery versus Intensive Lifestyle intervention study was a controlled clinical trial conducted from December 2005 to June 2009 at the Morbid Obesity Centre, Vestfold Hospital Trust, Tønsberg, Norway. A group of 139 morbidly obese subjects were treated either with GBS or ILI. Biochemical and clinical indices of cardiovascular and metabolic health were assessed at baseline and after 12 months of follow-up. Blood samples for hs-TnI analyses were available from 136 participants (94 female), out of whom 74 received GBS. Results: At baseline median hs-TnI levels were 2.35 (1.38-4.40) ng/L in the ILI group and 2.40 (1.28-3.95) ng/L in the GBS group (ns). After 12 months of follow-up, hs-TnI had decreased significantly more in the GBS group than in the ILI group (1.10 ng/L vs. 0.20 ng/L; p=0.002) (see Figure). Variables associated with the change in hs-TnI concentrations by univariate analyses included intervention group (p=0.002), changes in body mass index (p=0.002), body weight (p=0.003), waist circumference (p=0.04), serum total cholesterol (p=0.009), serum triglycerides (p=0.002) and HbA1c (p=0.017). Conclusions: In patients with morbid obesity, GBS was associated with a significantly greater reduction in hs-TnI than ILI, suggesting that bariatric surgery and/or large weight loss unloads the stressed heart and may lead to reduced cardiac mass and hemodynamic stress.