Balanced Set Research Articles

Comparison of Memory, Balance and Fear of Falling in Older Women After Performing Yoga and Square-stepping Exercises

Objectives Most falls in the elderly occur due to physical and cognitive risk factors. This study aims to compare the effect of two types of mind-body exercises, yoga and square-stepping exercise (SSE), on memory, balance, and fear of falling in older women. Methods & Materials A quasi-experimental study was conducted on 20 elderly women with an age range of 60 to 70 years. Participants were selected through purposive sampling and were randomly assigned to yoga and Square-Stepping groups. Both groups did exercise for 12 weeks and participated in a pre-test and post-test. The Wechsler memory test, stork test, berg balance test, and international falls efficacy scale were used to measure memory quotient, static balance, dynamic balance, and fear of falling, respectively. Analysis of variance with repeated measures was conducted to analyze the data Results The mean scores of memory quotient in the two groups after exercises were significantly higher than before exercises (F(1, 18)=32.692, P<0.001, η2=0.645). The mean static balance time in the yoga group was significantly higher than in the SSE group (F(1, 18)=60.755, P<0.001, η2=0.771). Furthermore, the mean dynamic balance score in the SSE group was significantly higher than in the yoga group (F(1, 18)=7.714, P=0.012, η2=0.300). In addition, the mean square of fear of falling in the SSE group was significantly lower than in the yoga group (F(1, 18)=11.777, P=0.003, η2=0.396). Conclusion It seems that square stepping exercises can also be used as a simple exercise program to improve physical and cognitive functions in older women.

Do Balance Scores Improve Due To Acute Myo-fascial Release In Collegiate Female Athletes

Do Balance Scores Improve Due To Acute Myo-fascial Release In Collegiate Female Athletes

Association between the oxidative balance score and estimated glomerular filtration rate: 2007–2018 NHANES

Oxidative stress is closely associated with the estimated glomerular filtration rate (eGFR) levels. A comprehensive indicator for evaluating dietary and lifestyle exposures to oxidative stress is the Oxidative Balance Score (OBS), with higher OBS suggesting more substantial antioxidant exposures. The aim of this study is to explore the relationship between OBS and eGFR levels. A total of 20,285 subjects were selected from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018. One-way and multifactorial linear regression analyses were used to assess the association of OBS with eGFR. The relationship between OBS and eGFR levels was also assessed using restricted cubic splines (RCS) analysis. OBS levels were significantly and positively correlated with eGFR levels, and eGFR values were more susceptible to OBS in males than in females. Our findings suggest that higher OBS scores may be associated with higher eGFR levels, highlighting the importance of adhering to an antioxidant diet and lifestyle, which can help prevent kidney disease.

Higher oxidative balance score is linearly associated with reduced prevalence of chronic kidney disease in individuals with metabolic syndrome: evidence from NHANES 1999-2018.

Oxidative stress is a key contributor to the development of chronic kidney disease (CKD) in individuals with metabolic syndrome (MetS). The oxidative balance score (OBS) is an emerging composite assessment tool for dietary and lifestyle oxidative balance. We aimed to explore the association of OBS with CKD prevalence in MetS in this national cross-sectional analysis. This was a national cross-sectional analysis. Eligible MetS participants ≥20 years of age from NHANES 1999-2018 were included. OBS was assessed according to previous well-validated methods and consisted of 16 dietary components and 4 lifestyle components. MetS was diagnosed by NCEP-ATP III criteria, while CKD was diagnosed by KDIGO 2021 Clinical Practice Guideline. Multivariate logistic regression models were used to explore the association of OBS with CKD in MetS in this national cross-sectional analysis. A total of 8,095 MetS participants were included, with a CKD prevalence of 24.8%. In fully adjusted models, each score increases in OBS, dietary OBS, and lifestyle OBS was associated with a 2, 1.7, and 7.3% reduction in the prevalence of CKD, respectively. Higher OBS, dietary OBS, and lifestyle OBS were all associated with significantly lower odds of CKD (p for trend all <0.05). Restricted cubic spline analysis showed that these associations all exhibited inverse dose-response. Interaction analyses indicated that cardiovascular disease (CVD) status significantly influenced the impact of OBS and dietary OBS, and these associations were only present in CVD-free subjects. Defining MetS using the IDF criteria did not significantly change the results. OBS was inversely associated with the prevalence of CKD in MetS, especially in CVD-free settings. These findings emphasize that adherence to an antioxidant diet and lifestyle contributes to the early prevention of CKD in the MetS population and necessitates attention to CVD interactions. Future prospective cohort studies are needed to confirm these results.

Understanding “Fear Of Falling” And How It Impacts Older Persons Motivation To Engage In Fall Prevention Exercise Interventions

Abstract Background Fear of falling can cause older persons to restrict their activities, which drives reduced strength and balance and increases their falls risk. Falls can have a significant effect on older persons in terms of loss of confidence, ongoing falls risk and ultimately, a poorer quality of life (Oliver et al, 2010). Fall prevention exercise interventions can help reduce the risk of falling in older adults by up to 34% (Sherrington et al, 2020). This study aims to explore the prevalence of fear of falling in older adults both before and after attending a community-based fall prevention exercise programme. The programme consisted of an evidence-based Physiotherapy led 10-week strength and balance class, followed by a 16-week exercise instructor led strength and balance class. Methods A 2-part qualitative study. Part 1: Prior to commencing the class each participant completed a rating of their fear of falling measured by ConfBal (a validated 10 item Balance Confidence scale). Part 2: Questionnaire assessing their experience of the classes and corresponding change in balance scores. Results 17 older adults completed the programme. Surveys were returned by 8/17 to date (47%). Mean pre-intervention ConfBal score of 20, mean post intervention score of 15 (8/17 participants to date), average 4-point improvement after intervention was statistically significant (p=0.008). Reported benefits of falls prevention exercise classes include peer-peer discussion of functional ability, gaining confidence by exercising in a group environment, practising functional exercises relating to day-to-day tasks, and building social relationships. Conclusion Fear of falling amongst community dwelling older adults is common but group exercise improves confidence as well as boosting social interactions. Participation in fall prevention exercise programmes can help to better support older people as they age which may influence better health outcomes in our communities.

Correlations between oxidative balance score and female asthma among U.S. adults

In order to explore the association of oxidative balance score (OBS) with female asthma among U.S. adults, we applied multiple logistic regression models, restricted cubic spline, and subgroup analysis using a cross-sectional study from the National Health and Nutrition Examination Survey (NHANES). 17,582 female out of the 91,351 participants from 2001 to 2018 in NHANES were enrolled in the analysis and 2,795 female participants had asthma. In three models, the OBS was negatively associated with female asthma incidence with the odds ratios (OR) = 0.99. When comparing the ratio of Q2, Q3, and Q4 of OBS quartiles against the Q1 quartile, the adjusted OR with 95% confidence intervals (95%CI) were 0.88 (0.75–1.03), 0.84 (0.73–0.97), and 0.82 (0.70–0.96) respectively, with p < 0.01 in the all covariates adjusted models. The restricted cubic splines indicated a linear relationship between OBS and female asthma. Subgroup analysis revealed no significant interaction effects except in the smoke group (p < 0.001), and there was a significant difference in the former smoker with OR 0.97 (0.96–0.99). We observed that there is negative relationship between OBS score and female asthma incidence, which suggests OBS probably is a protective factor for female on-set asthma. According to the subgroup analysis, smoking should be recommended to reduce asthma morbidity.

Association between oxidative balance scores and all-cause and cardiovascular disease-related mortality in patients with type 2 diabetes: data from the national health and nutrition examination survey (2007–2018)

BackgroundOxidative Balance Scores (OBS) is composite measures that assess the balance between pro-oxidant and antioxidant factors in an individual’s diet and lifestyle. Evidence on OBS and cardiovascular disease (CVD) in diabetic patients is scarce. This study investigates the potential association between OBS and CVD-prevalence and all-cause and CVD-related mortality in adult diabetic patients.MethodsParticipants were selected from the National Health and Nutrition Examination Survey (NHANES) 2007–2018. OBS-related data collection was initiated by linking the National Death Index to determine mortality due to all-cause and cardiovascular disease until December 31, 2019. Weighted logistic regression analyses explored the relationship between OBS and CVD. In addition, multivariable Cox proportional risk regression models and Kaplan–Meier curves were used to determine the correlation between OBS and mortality, with time to event as the time variable, as well as to estimate hazard ratios (HR) and 95% confidence interval (CI).ResultsA total of 3491 participants were included in the final analysis. Weighted logistic regression analysis of the relationship between OBS and CVD prevalence found that higher OBS was not associated with CVD prevalence compared with lower levels after fully adjustment in model 3 (OR: 0.82, 95% CI: 0.51–1.31, P = 0.39). During 3,491 person-years of follow-up, 408 deaths were recorded, of which 105 deaths were attributed to CVD. In fully adjusted model 3, participants in the highest quartile of OBS had significant reductions in all-cause mortality of 53% [HR: 0.47, 95% CI: 0.29–0.77), Ptrend= 0.002] and in cardiovascular disease mortality of 78% [HR: 0.22, 95% CI: 0.08–0.56), Ptrend= 0.004], compared with the lowest quartile groups of OBS. The Kaplan–Meier analysis results showed that participants in the highest quartile of OBS had the lowest risk of all-cause and CVD-related mortality and were statistically different (P < 0.05). Subgroup analysis confirmed that P for interaction was significant only concerning the educational level attained and in individuals with a history of CKD (P < 0.05).ConclusionsAlthough OBS wasn’t very useful for assessing CVD prevalence outcomes, higher OBS was significantly associated with lower all-cause and CVD-related mortality, suggesting that maintaining adequate OBS may reduce mortality in patients with DM.Graphical

Prevalence of Balance Impairment in Physically Active and Sedentary Lifestyle Children Aged 7-10 Years

Background: Balance impairment can significantly affect motor development in children, with lifestyle factors such as physical activity playing a crucial role. Physically active children may develop better balance than those leading sedentary lifestyles.Objective: To evaluate the prevalence of balance impairment in physically active and sedentary children aged 7-10 years.Methods: A cross-sectional study was conducted on 377 children aged 7-10 years from schools in Sheikhupura, Pakistan. The participants were divided into physically active (n=189) and sedentary (n=188) groups based on the International Physical Activity Questionnaire for Children (IPAQ-C). Balance was assessed using the Pediatric Balance Scale (PBS), a 14-item tool with a maximum score of 56. Data were analyzed using IBM SPSS version 25, with chi-square tests to determine statistical significance (p&lt;0.05).Results: In the physically active group, 79.4% (n=150) had good balance scores, while 67.6% (n=127) in the sedentary group showed moderate balance impairment. The difference between the two groups was statistically significant (p&lt;0.001).Conclusion: Physically active children demonstrated better balance compared to their sedentary peers, underscoring the importance of physical activity in childhood development

Effects of Neuromuscular Exercise on Dynamic Balance, Vertical Jump and Trunk Endurance in Ice Hockey Players: A Randomized Controlled Trial

This study aims to investigate the impact of a 12-week neuromuscular exercise program on balance, vertical jump, and core endurance parameters in female ice hockey players. Y balance test, vertical jump test and McGill test were used for evaluation of dynamic balance, vertical jump and trunk endurance, respectively. A 12-week training program was conducted on 50 female ice hockey players. The exercise group showed significant differences in anterior and posteromedial balance scores for both right and left (p&amp;lt;0.05), but there was no significant difference in posterolateral scores (p&amp;gt;0.05). The control group didn't show significant improvements in the vertical jump (p&amp;gt;0.05), while the neuromuscular exercise group demonstrated a statistically significant improvement (p&amp;lt;0.05). Trunk extension endurance improved significantly in the control group (p&amp;lt;0.05), but there were no significant differences in trunk flexion and lateral endurance (p&amp;gt;0.05). In contrast, the neuromuscular exercise group significantly improved all trunk endurance values (p&amp;lt;0.05). Neuromuscular exercise training applied to ice hockey players can improve the balance, vertical jump, and trunk endurance parameters. Therefore, the inclusion of neuromuscular exercise programs in the training programs of female ice hockey players can enhance their physical performance and may reduce the risk of injury.

Systematic review of Janus kinases inhibitors for rheumatoid arthritis: methodology, reporting, and quality of evidence evaluation.

To evaluate the methodological, reporting and evidence quality of systematic reviews or meta-analyses of Janus kinases (JAK) inhibitors for the treatment of rheumatoid arthritis (RA). Our study systematically retrieved reviews from various databases, spanning from inception to June 2024. Two evaluators independently assessed the methodological, reporting, and evidence quality of each review using the AMSTAR-2 and PRIAMA2020 tools. The evidence quality was evaluated according to GRADE criteria. Six aspects were evaluated: publication year, study type, homogeneity, risk of publication bias, AMSTAR-2 methodology, and PRIAMA2020 reporting quality. Excel 2016 facilitated conversion of scores into radar plots. Following stringent selection criteria, a total of 18 relevant studies were identified. The AMSTAR-2 scores ranged from 4 to 13 points, with five studies rated as low quality and the remaining 13 as critically low quality. All studies encompassed populations, interventions, controls, and outcome measures, demonstrating commendable integrity. However, there is room for improvement in study protocol development and registration, comprehensive search strategies, inclusion and exclusion criteria, conflict of interest disclosure, and discussion of heterogeneity. PRIAMA2020 assessments ranged from 14.5 to 21 points, with two studies scoring below 15 points due to increased bias risk from data transformation and sensitivity analysis. Notably, all reviews (100%) adhered to PRIAMA2020 guidelines for certain items but none met all criteria. GRADE evaluation included 446 outcome measures, with 158 of moderate, 156 of low, and 132 of very low quality, indicating JAK inhibitors is effective in improving RA. According to radar chart, the average rank score was 13.13. One study achieved a balanced score across all dimensions, while 11 exceeded the average, five showed significant differences in PRIAMA2020 scores, and four in AMSTAR two scores. Despite summarizing the efficacy and safety of JAK inhibitors in treating RA, the included studies exhibited poor methodological and reporting quality, along with low-quality evidence overall. Therefore, caution is warranted among decision-makers regarding the use of JAK inhibitors in RA treatment. Urgent requirements include high-quality, multicenter studies investigating JAK inhibitors for RA. https://www.crd.york.ac.uk/PROSPERO, identifier 413415.

Organizational Culture and Performance of Quasi-Public Institutions Within the Pension Industry in Kenya: A Case of Local Authorities Pension Trust

This study intended to examine the organizational culture and performance of quasi-public institutions within the pension industry in Kenya with a focus on Local Authorities Pension Trust. Key theories under review in this research paper were the Balance Score Card theory, Scheins organizational culture theory and Institutional theory. Descriptive research design was employed and utilized by this research. The 224 staff working in Local Authorities Pension Trust offices across the country formed the target population of this study. In order to determine the sample size, simple random sampling was utilized. For this research, the researcher utilized a questionnaire to collect data from responders. There were both open-ended and closed-ended questions on the survey. To determine the connection between organizational culture and performance, the researcher did a multiple regression analysis. Questionnaires were utilized for gathering quantitative data, which were then evaluated employing descriptive statistics in SPSS and displayed in the form of tables, pie charts, and bar graphs. The data gathered was leveraged to create pie charts, bar graphs, and tables that illustrated facts about the link between organizational culture and performance at Local Authorities Pension Trust. The study found that a balanced mix of clan culture, adhocracy culture, market culture and hierarchical culture had a positive significant effect on the performance of LAPTRUST. The study concludes that in a clan culture, employees are encouraged to participate in decision-making processes, share their ideas, and contribute to the overall success of the organization. The study recommended that the organization should encourage cross-functional teams and collaboration across departments to break down silos and promote innovation. The organization should invest in training programs that enhance employees' market knowledge and skills can contribute to a market culture. The organization should clearly define and communicate the roles and responsibilities of each level within the hierarchy, ensuring that employees understand their position and how it fits into the overall organizational structure.

Normative data on nasalance scores for French speaking children

IntroductionThe objectives of this study are to establish normative nasalance values in European French for children aged 8–10 years, to study the factors likely to influence nasalance values, and to ensure that the nasometer allows the differentiation of control subjects from subjects with velopharyngeal insufficiency. MethodsNasal balance scores were calculated using the Nasometer II 6450 (KayPENTAX) for 50 control subjects producing 31 verbal stimuli specifically designed for the French language. Nasalance scores were analyzed and compared with 7 subjects with velopharyngeal insufficiency. ResultsThis study provided nasalance norms for each verbal stimulus. The phonetic content of the stimuli (nasality, vowel height, voicing) was a major factor influencing the nasalance score. However, the characteristics of the speaker (gender and age) had a non-significant effect, with the major exception of the presence or absence of velopharyngeal insufficiency. ConclusionThis study confirmed the need to use established normative values in the patient's language and for each verbal stimulus. Although the effect of vowel height on the nasalance score has been demonstrated, this study is the first to show an effect of voicing. Once normative nasalance scores are established, a validation study with a larger pathological population will be necessary.This study establishes normative nasalance scores in European French in children.

The Effect of Rood's Ontogenic Motor Patterns on Trunk Control and Balance in Spastic Diplegic Cerebral Palsy Children

Background: Cerebral palsy (CP) is a non-progressive neuromotor disorder affecting movement, muscle tone, and posture due to brain injury during early development. Effective interventions are essential for improving functional outcomes in children with spastic diplegic CP.Objective: This study aimed to evaluate the effects of Rood's Ontogenic Motor Patterns (ROMP) on trunk control and balance in children with spastic diplegic cerebral palsy.Methods: A single-blinded randomized clinical trial was conducted with 22 children aged 3-10 years, diagnosed with spastic diplegic CP. Participants were randomly assigned to two groups: Group A received Functional Electrical Stimulation with ROMP, and Group B received conventional physical therapy. The intervention lasted five weeks, with three sessions per week. Outcomes were assessed using the Modified Ashworth Scale, Gross Motor Function Measurement Scale (GMFM-88), and Pediatric Berg Balance Scale. Data were analyzed using SPSS 27.Results: Group A showed significant improvement in balance (PBBS: pre 13.81 ± 1.64, post 24.18 ± 4.67; p=0.017) and GMFM-88 scores (pre 9.95 ± 109.50, post 15.73 ± 173.0; p&lt;0.001). Spasticity reduced significantly in the ROMP group (MAS: pre 11.50 ± 126.50, post 7.30 ± 73.00; p=0.010).Conclusion: ROMP significantly improved balance and reduced spasticity in children with spastic diplegic CP compared to conventional therapy, suggesting its potential integration into rehabilitation programs.

Debate: How much should nonspecialists be involved in mental health care when resources are limited? A perspective from low- and middle-income countries.

Millions of children and young people (CYP) in low- and middle-income countries (LMICs) have no access to mental health care. This huge treatment gap is primarily due to limited availability of trained mental health professionals. We propose task-sharing as a scalable strategy to expand access to child and adolescent mental health (CAMH) interventions in LMICs. Task-sharing involves using the few mental health specialists in LMICs to train and supervise nonspecialists to provided CAMH interventions. There is strong evidence of clinical and cost effectiveness of task-shared mental health interventions for adults in LMICs and promising evidence for CYP. To succeed, task-shared programmes need to be embedded in a balanced system-wide care setting that includes stakeholder involvement. The existing mental health specialists may require additional training in leadership, supervision, mentoring, service design and evaluation in order to meet the additional expectations of managing task-sharing programmes. The nonspecialists to be trained would need assurances about workload, ongoing supervision, clinical back up for cases that exceed their expertise, certification for their training and career progression. CAMH task-sharing offers good promise for increasing CYP's access to mental health interventions in LMICs. However, planners need to be aware of the important practical, ethical and contextual considerations necessary for success and sustainability.

Data base of Cognitive functions and their relation to balance and agility in athletes from differents sports branches

Successful performance in each sport requires high ability in various features, including motor and perceptual-cognitive skills. This study aimed to compare the balance and agility in athletes from several sports branches to find out how cognitive functions relate to these parameters. Seventy-three individuals aged 18-30 were included in this prospective-descriptive study. In the assessment of cognition, Montreal Cognitive Assessment Scale, d2 Test of Attention, and a Bassin Anticipation Timer Device were used. While Prokin-TecnoBody was used to measure the balance skills, Illinois Agility Test (IAT) was used for agility. IAT times showed positive weak correlations with both the absolute error-score (AES) at 8mph (r=0.260, p=0.040) and mediolateral balance score (ML)(r=0.255, p=0.043). While there was a negative weak correlation between AES at 3mph and anteroposterior score of balance (r=-0.267, p=0.035), we found positive weak correlation between AES at 8mph and ML of balance (r=0.253, p=0.046). It was found that the IAT scores of the sedentary group were significantly lower than athletes (p=0.000). According to AES at 3mph, there were significant differences between tennis players and both sedentary and volleyball players (p=0.008, p=0.002, respectively). When the AES at 8mph compared, the only statistically significant difference was between tennis players and sedentary (p=0.008). In conclusion, this study shows how cognitive functions, particularly coincidence anticipation timing (CAT), correlate with essential physical performance factors like agility and balance across different sport branches, suggesting that improving cognitive skills could enhance overall athletic performance and inform mental training strategies in sports. It is recommended that future sports science research focus on enhancing CAT through targeted training programs.

Cognitive functions and their relation to balance and agility in athletes from different sports branches

Successful performance in each sport requires high ability in various features, including motor and perceptual-cognitive skills. This study aimed to compare the balance and agility in athletes from several sports branches to find out how cognitive functions relate to these parameters. Seventy-three individuals aged 18-30 were included in this prospective-descriptive study. In the assessment of cognition, Montreal Cognitive Assessment Scale, d2 Test of Attention, and a Bassin Anticipation Timer Device were used. While Prokin-TecnoBody was used to measure the balance skills, Illinois Agility Test (IAT) was used for agility. IAT times showed positive weak correlations with both the absolute error-score (AES) at 8mph (r=0.260, p=0.040) and mediolateral balance score (ML)(r=0.255, p=0.043). While there was a negative weak correlation between AES at 3mph and anteroposterior score of balance (r=-0.267, p=0.035), we found positive weak correlation between AES at 8mph and ML of balance (r=0.253, p=0.046). It was found that the IAT scores of the sedentary group were significantly lower than athletes (p=0.000). According to AES at 3mph, there were significant differences between tennis players and both sedentary and volleyball players (p=0.008, p=0.002, respectively). When the AES at 8mph compared, the only statistically significant difference was between tennis players and sedentary (p=0.008). In conclusion, this study shows how cognitive functions, particularly coincidence anticipation timing (CAT), correlate with essential physical performance factors like agility and balance across different sport branches, suggesting that improving cognitive skills could enhance overall athletic performance and inform mental training strategies in sports. It is recommended that future sports science research focus on enhancing CAT through targeted training programs.

Association Between Periconceptional Diet Quality and Hypertensive Disorders of Pregnancy: The Japan Environment and Children's Study.

Little is known about the relationship of healthy diets, which are widely recommended to prevent diseases in general populations, with the risk of hypertensive disorders of pregnancy (HDP), particular among non-Western populations with different dietary habits. We aimed to investigate the association between periconceptional diet quality and the risk of HDP among pregnant Japanese women. Dietary intake over 1 year before the first trimester of pregnancy was assessed using a validated, self-administered food frequency questionnaire among 81 113 pregnant Japanese women who participated in a prospective cohort of the Japan Environment and Children's Study. Overall diet quality was assessed by the Balanced Diet Score (BDS) based on adherence to the country-specific dietary guidelines and the Dietary Approaches to Stop Hypertension (DASH) score. Cases of HDP were identified by medical record transcription. The association between diet quality and HDP risk was examined using Bayesian logistic regression models with monotonic effects. We identified 2383 (2.9%) cases of HDP. A higher BDS was associated with a lower risk of HDP. When comparing the highest with the lowest quintile of the BDS, the adjusted odds ratio (aOR) of HDP was 0.83 (95% credible interval [CrI], 0.73-0.94). The DASH score and HDP risk were inversely associated in a monotonic dose-response manner (aOR per 1-quintile increase in the DASH score, 0.92 [95% CrI, 0.89-0.95]). A high-quality diet, which is recommended for disease prevention in general populations, before conception may also reduce the risk of HDP among pregnant Japanese women.

Relationship between oxidative balance score and prostate cancer: a cross-sectional study of NHANES, 1999–2010

ObjectiveFew studies have examined the relationship between systemic oxidative stress and prostate cancer (PCa) risk. This study aimed to explore potential correlations between PCa and oxidative balance score (OBS), which...

A useful cognitive motor dual task paradigm in prodromal and manifest Huntington’s disease

IntroductionIndividuals with Huntington's disease (HD) experience increased difficulty with balance throughout disease progression. Adding a simultaneous cognitive task to a balance assessment, referred to as a dual task (DT) paradigm, may have a deleterious effect on balance, which can be expressed in terms of a Dual Task Cost (DTC), relative to a single task (ST) condition. The aim of this study is to explore whether a cognitive-motor DT paradigm uncovers balance deficits in prodromal (Pro-HD) and manifest HD, compared to healthy adults (HA). MethodsBalance under ST and DT conditions was examined using the BTracks Balance Plate and Balance software in 30 individuals with HD, 17 individuals with Pro-HD, and 20 HA. During the DT condition, participants were simultaneously administered a version of the Paced Auditory Serial Addition Test (PASAT). DTC is calculated as the relative ratio of ST to DT, controlling for ST performance: DTC= (ST − DT)/ST x100. ResultsThe HA group performed significantly better than the HD group on both the ST and DT conditions (p < 0.01), while balance scores between the HA and the Pro-HD groups were not significantly different. The DTC scores, however, were significantly better in the HA compared to both the HD (p < 0.001) and Pro-HD (p < 0.05) groups. ConclusionOur findings indicate that the addition of a cognitive task interferes with participant's balance, reflecting real-life performance, and may have additional value for estimating transition to manifest disease, appraising fall risk, or serving as a valid outcome measure in observational and interventional trials in HD.

Towards a Reinvigoration of the Risk Management Framework for the Scope of Upgrading Prudential Surveillance

This article discusses financial stability related notions of risk, the issue of convergence and cross financial sector prudential intervention. It elucidates the Basel framework shortcomings and enunciates the requirement of setting a reinvigorated prudential framework before proceeding to its essentials in terms of engineering. It highlights an early warning approach dealing with the issue of time reaction mismatch of the prudential authority and the priority of setting a long run forwarded guided approach. The objective of this research is to provide a clue into enhancing prudential setting of instruments, the forwarded guided purview of surveillance as well as hedging and the Balanced Score Card.