Problem statement and purpose. During the post-socialist period Kyiv began to demonstrate itself not only as an industrial centre, but also as a business centre, which had contributed to the dynamic development of the office real estate. During the second half of the 1990s, most of the offices were concentrated in the Central Business District, and after the financial crisis of 2008, the emphasis in office construction had shifted to the middle and peripheral areas of the city. These shifts were caused by the lack of suitable areas for the office construction, compact building design, high land cost, transport problems, the lack of opportunity to create the ap propriate infrastructure for new construction or reconstruction in the capital central part. That’s why the industrial areas of the middle and peripheral city zones with abandoned industrial enterprises are especially important for the study of expediencyof their usage in the modern economic realities not only for creating innovative industrial enterprises, but also for business centres, office centres and business units. The purpose of the study is to find out the patterns of the office real estate spatial organisation in the large city. Data & Methods. The information base of the research is the statistical data of the Main Department of Statistics in Kyiv, analytical materials of the commercial real estate agency Colliers International, the consulting company Ukrainian Trade Guild and field research results. During the research such methods as field research, historical-geographical, comparative-geographical, statistical, cartographic, GIS‑technologies were used. Results. The transformation of Kyiv’s urban space in the period of post-socialist transformations is accompanied by significant changes in the urban space structure. The significant concentration of business centres and office centres is observed in the city central part, which is mainly the result of a new construction, which has affected the planning structure and architectural heritage in a bad way. The transformation have occurred in the industrial areas, where as a result of deindustrialization the share of construction under industrial enterprises have declined and under commercial buildings continues to increase. Mostly such industrial areas are located near the important highways and the subway lines. It is proved that the peripheral areas, which are located near the main transport arteries, have a significant potential for the construction of business centres and office centres. Taken into account the negative processes observed in the city central part, the interests of investors should be focused on creating areas specialised in the business services within degraded industrial areas in distant city zones, which is the strategic interests of the large city spatial development.