The soil erodibility factor (K) is the main data required for regional soil erosion investigation and mapping using soil erosion models. Fine mapping of K and the study of the applicability of different K estimation methods at the global scale are important to improve the accuracy of global soil erosion evaluation. In this study, the USLE-K, RUSLE2-K, EPIC-K and Dg-K algorithms were used to calculate and compare the global K, and a global measured K database was established by using literature backtracking method and retrieval tool method. Spatial pattern and applicability analysis were carried out on the results of the above four algorithms. The four algorithms were corrected according to the measured K database. The results showed that (1) the global K spatial patterns obtained by the four algorithms were similar but slightly different, with the result of RUSLE2-K being the closest to the measured K, followed by the USLE-K and the EPIC-K, and the result of Dg-K differing significantly from the measured K. (2) The global K distribution characteristics showed some regularity with soil properties, such as soil silt content and sand content, with silt content having the greatest influence on K. (3) The results calculated by the corrected RUSLE2-K and USLE-K algorithms could meet the model applicability conditions and coincided with the results of local K mapping. The results of K mapping in this study on a global scale and the results of the comparative analysis of the applicability of different algorithms provide the necessary scientific basis for the selection of K algorithms globally and quantitative evaluation of soil erosion.