Background: Brazil has the second biggest transplant system in the world. The organ donation rates, however, are still low. To persuade the population towards the theme, media interventions are broadcast regularly. Thus, this article analyses how media intervention in the form of advertising campaigns, telenovelas, and TV news can raise the rates of donations, and then, reduce the shortage of organs in Brazil. Method: We obtained data from the Brazilian Association for Organ Transplantation (ABTO), the Brazilian Health Ministry (HM), the Brazilian Institute for Geography and Statistics (IBGE), Globoplay, and other media sources to build a panel with quarterly data from 2009 to 2019, by state. Then we used fixed-effect panel regression models, with healthcare supply, and demographics as control variables to ascertain the effect of the media variable on organ donations during this period. Findings: The results indicate that media interventions can increase the number of organ donations. The coefficient of media interventions is significant and positive for telenovelas (95% C.I 0.156-0.164), not significant individually for news or government advertising campaigns. It makes telenovela's representations of organ donation an effective tool of awareness. We tested the combinations of the different types of interventions, and the joint effect of telenovelas and news reaches the highest impact on organ donations (99% C.I 0.198-0.208). Some important variables were found significantly related to organ donation as well; as the numbers of brain death notifications (99% C.I 0.113-0.117) and transplant beds (95% C.I 0.153-0.161). Interpretation: Institutional campaigns can learn several strategies from the entertainment media. Empirically, the presence of media interventions in the form of telenovelas impacts organ donation as much as improvements in the healthcare system. This suggests that one of the main problems affecting organ shortage is public opinion, and that opinion is responsive to the right incentives. Funding Information: There was no funding source for this study. Declaration of Interests: We declare no competing interests.