Memory Awareness Research Articles

Optimal energy efficient, load aware memory management system on SoC’s for industrial automation

Optimal energy efficient, load aware memory management system on SoC’s for industrial automation

Reliability of patient self-report of cognition, awareness, and consciousness during seizures.

ObjectiveClinicians rely on patient self‐report of impairment during seizures for decisions including driving eligibility. However, the reliability of patient reports on cognitive and behavioral functions during seizures remains unknown.MethodsWe administered a daily questionnaire to epilepsy patients undergoing continuous video‐EEG monitoring, asking about responsiveness, speech, memory, awareness, and consciousness during seizures in the preceding 24 hours. We also administered a questionnaire upon admission about responsiveness, speech, and awareness during seizures. Subjective questionnaire answers were compared with objective behavioral ratings on video review. Criteria for agreement were Cohen’s kappa >0.60 and proportions of positive and negative agreement both >0.75.ResultsWe analyzed 86 epileptic seizures in 39 patients. Memory report on the daily questionnaire met criteria for agreement with video review (κ = 0.674 for early, 0.743 for late recall). Subjective report of awareness also met agreement criteria with video ratings of memory (κ = 0.673 early, 0.774 late). Concordance for speech was relatively good (κ = 0.679) but did not meet agreement criteria, nor did responsiveness or consciousness. On the admission questionnaire, agreement criteria were met for subjective report of awareness versus video ratings of memory (κ = 0.814 early, 0.806 late), but not for other comparisons.InterpretationPatient self‐report of memory or awareness showed the best concordance with objective memory impairment during seizures. Self‐report of impairment in other categories was less reliable. These findings suggest that patient reports about impaired memory during seizures may be most reliable, and otherwise determining functional impairments should be based on objective observations.

Which cognitive and linguistc factors influence phonological processing in adolescents?

To characterize phonological processing of adolescents and to identify language skills and cognitive functions that influence their age group. 83 typical adolescents aged from 11 to 16 years of age participated in the research. Phonological awareness tests, rapid automatic naming, neuropsychological assessment and reading were used. Descriptive analysis and linear regression were carried out with a 5% significance level. Regarding phonological processing, a lower performance was found in the phonemic segmentation task, longer times for object naming and performance as were expected for working memory of the age range. There was a reciprocal association between rapid naming of objects, letters and working memory, between rapid naming of letters and phonological awareness. Executive functions and attention influence working memory and phonological awareness. Semantic episodic verbal memory influenced working memory and reading, phonological awareness. The performance in phonological processing was influenced by linguistic and cognitive skills which suggests they are still improving in adolescents.

19세기 동아시아 중화질서의 변동과 한‧중 상호인식의 기억과 변용

In the 19th century, Lee Eu-june's 『MongyooYeonhaengrok(夢遊燕行錄)』 and Bo Jun's 『FengshiChaoxianyichengriji(奉使朝鮮驛程日記)』, in examining the changes in the Chinese order in East Asia, the relationship of Korea-China, the memory and transformation of mutual recognition, and the aspects of literary exchange can be said to be a historically and academically meaningful material. This thesis was conducted in three main parts based on the above contents. First, the changes in the 19th century East Asian Chinese order and the relationship between Korea and China were studied in Lee Eu-june's 『MongyooYeonhaengrok』 and Bo Jun's 『FengshiChaoxianyichengriji』. Second, the memory and transformation of mutual awareness between Korea and China during this period was explored, and finally, the exchange of intellectuals between the two countries was considered based on the poems found in these works. Traditionally, the key factor in the relationship between Korea and China is the Chinese ideology. Relations between Korea and China had been settled in the framework of Chinese ideology, and Chinese ideology dominated the consciousness of intellectuals. However, as a new international relationship was formed in East Asia in the 19th century, the relationship between the two countries began to show cracks and changes. In addition, the perceptions and attitudes of intellectuals toward China and Chinese culture are also changing. Lee Eu-june's 『MongyooYeonhaengrok』 presents a shift and change in the traditional relationship between Korea and China, and a change in perception. In addition, Lee Eu-june's critique of China can be said to reflect the universal perception of the Joseon intellectual society in the 19th century. In particular, in the relationship between Korea and China during this period, the consciousness of ‘small-China’ and ‘Chosun-Chinese’ acted as an important variable. On the other hand, it can be said that the perceptions and attitudes toward the relationship between Korea and China and the Sino-Chinese order in Bo Jun's 『FengshiChaoxianyichengriji』 reflect the traditional perception of the historical center and periphery, and the relationship between tribute and tribute. Bo Jun recognizes the relationship between Korea and China in terms of China, which is still the ‘center’ and the ‘periphery’, Joseon. Second, in relation to the memory and transformation of mutual awareness between Korea and China, the composition of the center and the periphery in the traditional relationship between Korea and China works as a mechanism to understand the memory and transformation of mutual awareness. In fact, it can be said that the recognition of 'centre-periphery' provides a useful framework for understanding the implications of Chinese culture and their perceptions and attitudes toward Joseon intellectuals. However, after Oing(淸) ruled the Central Plains, the concept of China began to expand. This is because it was necessary to explain in detail the superiority of China to the ‘barbarity’ of Qing, which was a miracle. And this leads to Joseon intellectuals' concerns about the current reality. In 『MongyooYeonhaengrok』, Lee Eu-june reveals the historical events, people, regions, and perceptions of Chinese politics and society in Joseon and China. 「ChaoXianZhuzhici(朝鮮竹枝詞)」 recorded in 『FengshiChaoxianyichengriji』 records the history and culture, customs and geography of Joseon, and the life of the people. Here, Bo Jun reflects on the history of Korea and China and reveals his awareness of Joseon. Third, Lee Eu-june and Bo Jun expressed their views through an exchange of poems and, on the other hand, had literary exchanges. Considering this, the poems of Lee Eu-june and Bo Jun provide a cross-section of literary exchange between Korea and China during this period.

Evaluation of Episodic and Lexical Metamemory and Executive Function in Healthy Older Adults

In older adults, it is important to maintain awareness of memory as well as memory performance. However, it is not clear whether the awareness of episodic and lexical memory changes with age and is related to self-evaluation of memory and executive function. Here age-related changes and the relationship between metamemory, executive function, and metamemory scale were investigated. Healthy old (n=40) and young (n=34) groups participated in this study. In the episodic memory task, participants were asked to memorize ten Kanji words and to estimate the number of words they could recall after ten minutes. In the lexical memory task, they rated the likelihood that they could write a target Kanji word written in hiragana and then wrote them down. They were also asked to complete the metamemory in adulthood(MIA) and the position stroop task. In the episodic and lexical memory and the position stroop task and MIA subscales, the performances of the younger group were significantly better than those of the older group. In the episodic memory task, there were correlations between the metamemory and MIA subscales in both groups, but in the lexical memory task, only in the old group. No correlation was found between the results of both memory tasks and the stroop test. These results suggest that older people overestimate memory performances in the episodic and lexical memory tasks and metamemory performances may be associated with self-evaluation of memory. In addition, metamemory might not be related to frontal lobe function as shown in executive function tasks.

Self-awareness for financial decision making abilities is linked to right temporal cortical thickness in older adults.

Everyday financial decision making and the awareness of the integrity of one's financial decision making abilities (or financial awareness) are both critical to study in older adults as they can help identify those at risk for making suboptimal financial decisions and prevent financial loss. In the current study, we examined the cognitive and cortical thickness correlates of financial decision making and financial awareness in 59 community-dwelling participants co-enrolled in a larger study (mean age=68.35 years (SD=5.5), mean education=15.91 (SD=2.36), 61% = women, 67% = White, 30% = Black participants). Data from standardized measures of financial decision making and cognition was investigated along with FreeSurfer (v. 5.3) derived thickness regions. Based on metacognitive frameworks, financial awareness was measured along with a well-validated measure of memory awareness. Results revealed that numeracy, executive functioning and vocabulary were associated with financial decision making, whereas in analysis adjusted for financial decision making, memory awareness relative to cognition was most strongly linked to financial awareness. No significant associations between thickness and financial decision making were found. However, both financial and memory awareness were associated with the same right-hemisphere temporal thickness regions underscoring the idea of a common substrate of awareness. Interestingly, our findings converge with the emerging work on financial exploitation in which the right sided temporal regions have been found to play a prominent role. Incorporating the contributing role of self-awareness in various models of financial exploitation will be an important consideration for future studies.

Are Different Types of Learning Disorder Associated With Distinct Cognitive Functioning Profiles?

Introduction: DSM-5 presented a revised conceptualization of specific learning disorders (LD). Contrary to former versions, the various types of LD—i.e., mathematics disorder, reading disorder, and writing disorder—are not treated as distinct diagnostic entities but are integrated into one single LD category. In support of this new classification, it has been argued that the various types of LD overlap to a great extent in their cognitive functioning profiles and therefore do not exhibit a distinct set of cognitive causes. In contrast, ICD-11 still adheres to the idea of discrete categories and thus follows the specificity hypothesis of LD. Using latent profile analysis (LPA), we therefore tested the specificity of cognitive strengths and weaknesses in children with different types of LD. Secondly, we aimed at examining the extent to which observed LD characteristics (type and severity of LD as well as IQ-achievement discrepancy) were consistent with the membership of a given latent profile.Method: 302 German third-graders (134 girls; IQ ≥ 85; Mage = 111.05 months; SD = 5.76) with single or comorbid types of LD in the domains of mathematics, reading, and spelling completed a wide range of domain-specific and domain-general cognitive functioning measures.Results: Five qualitative distinct profiles of cognitive strengths and weaknesses were identified. Profile 1 (23% of the sample) showed Comprehensive Cognitive Deficits, performing low in all measures except for naming speed, language, and inhibition. Profile 2 (21%) included children with a Double Deficit in Phonological Awareness and Phonological Short-term Memory. Profile 3 (20%) was characterized by a Double Deficit of Phonological Awareness and Naming Speed. Profile 4 (19%) included children with a Single Deficit in Attention, and profile 5 (17%) consisted of children without any cognitive deficits. Moreover, type and severity of LD as well as IQ-achievement discrepancy discriminated between the profiles, which is in line with the specificity hypothesis of LD.Discussion: Overall, the finding of specific associations between the LD types and the identified cognitive profiles supports the ICD-11 classification of LD. Yet, those inferences may not be valid for an individual child but need to be examined through comprehensive diagnostic.

How did a novice translator form the view of translation?: a multi-textual investigation of Lin Yutang at St John’s University

ABSTRACT The current study highlights Lin Yutang’s view of translation at St. John’s University from 1911 to 1916, a period totally ignored in the research of Lin as a translator. With a multi-textual investigation of his articles at the St. John’s Echo, this research mainly addresses three questions: what Lin translated in his series of articles at the St. John’s Echo; how he conducted his task of translating; and why he formed his own style of translating. The first two doubts are respectively solved by Lin’s translational activities and translational strategies, while the last is approached via an analysis of his awareness in translation. The findings indicate that Lin Yutang, as a novice translator, not only conducted cultural translation, but also developed his ability in translation criticism and gradually formed his style of translating in his translingual writing; more significantly, Lin developed three awareness of translation, namely, the awareness of cultural memory, cultural comparison and cultural reflexivity –––– all these enrich his cultural self-consciousness, an indispensable part of Lin Yutang’s view of translation in his youth.

Impaired Memory Awareness and Loss Integration in Self-Referential Network Across the Progression of Alzheimer's Disease Spectrum.

Anosognosia, or unawareness of memory deficits, is a common manifestation of Alzheimer's disease (AD), but greatly variable in subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI) subjects. Self-referential network (SRN) is responsible for self-referential processing and considered to be related to AD progression. Our aim is to explore connectivity changes of SRN and its interaction with memory-related network and primary sensorimotor network (SMN) in the AD spectrum. About 444 Alzheimer's Disease Neuroimaging Initiative subjects (86 cognitively normal [CN]; 156 SCD; 146 aMCI; 56 AD) were enrolled in our study. The independent component analysis (ICA) method was used to extract the SRN, SMN, and memory-related network from all subjects. The alteration of functional connectivity (FC) within SRN and its connectivity with memory-related network/SMN were compared among four groups and further correlation analysis between altered FC and memory awareness index as well as episodic memory score were performed. Compared with CN group, individuals with SCD exhibited hyperconnectivity within SRN, while aMCI and AD patients showed hypoconnectivity. Furthermore, aMCI patients and AD patients both showed the interruption of the FC between the SRN and memory-related network compared to CN group. Pearson correlation analysis showed that disruptive FC within SRN and its interaction with memory-related network were related to memory awareness index and episodic memory scores. In conclusion, impaired memory awareness and episodic memory in the AD spectrum are correlated to the disconnection within SRN and its interaction with memory-related network.

Memory precision for salient distractors decreases with learned suppression

Attention operates as a cognitive gate that selects sensory information for entry into memory and awareness (Driver, 2001, British Journal of Psychology, 92, 53–78). Under many circumstances, the selected information is task-relevant and important to remember, but sometimes perceptually salient nontarget objects will capture attention and enter into awareness despite their irrelevance (Adams & Gaspelin, 2020, Attention, Perception, & Psychophysics, 82[4], 1586–1598). Recent studies have shown that repeated exposures with salient distractor will diminish their ability to capture attention, but the relationship between suppression and later cognitive processes such as memory and awareness remains unclear. If learned attentional suppression (indicated by reduced capture costs) occurs at the sensory level and prevents readout to other cognitive processes, one would expect memory and awareness to dimmish commensurate with improved suppression. Here, we test this hypothesis by measuring memory precision and awareness of salient nontargets over repeated exposures as capture costs decreased. Our results show that stronger learned suppression is accompanied by reductions in memory precision and confidence in having seen a color singleton at all, suggesting that such suppression operates at the sensory level to prevent further processing of the distractor object.

Family members' perspectives on learning cognitively unimpaired older adults' amyloid-β PET scan results.

Disclosure of Alzheimer's disease (AD) risk information to cognitively unimpaired older adults may become more common if preclinical AD is shown to be identifiable and amenable to treatment. Little, however, is known about how families will react to this information. Semi-structured telephonic interviews. Seventy study partners (mean age=68 [±11]; 50% female; 70% spouses/significant others; 18% children, siblings; 12% friends) of cognitively unimpaired adults who learned a personalized AD dementia risk estimate and an amyloid-β PET scan result through their participation in preclinical AD research. Interviewees were asked about their desire for information regarding their family member's AD dementia risk, baseline expectations of risk, understanding of amyloid-β PET scan results, and the impact of AD dementia risk information on emotions, health behaviors, and future plans, as well as on perceptions of their family member's or friend's memory. Interviewees generally understood the AD dementia risk information (83%) and considered it valuable (75%). Risk information perceived as favorable elicited feelings of happiness and relief; unfavorable information elicited disappointment, as well as increased awareness of the participants' memory and monitoring for incipient changes in cognition. While noting that AD dementia risk information was not medically actionable at this time due to the lack of disease-modifying therapies, some interviewees described changes to their family members' and their own health behaviors and future plans. Guidelines for the disclosure of AD dementia risk estimates and biomarker results to cognitively unimpaired adults should account for the needs and interests of individuals and their family members, who may step into a pre-caregiver role.

Concurrent predictors of word reading and reading comprehension for 9-year-olds with Williams syndrome

We examined the cognitive, language, and instructional factors associated with reading ability in Williams syndrome (WS). Seventy 9-year-olds with WS completed standardized measures of real-word reading, pseudoword decoding, reading comprehension, phonological skills, listening comprehension, nonverbal reasoning, visual-spatial ability, verbal working memory, rapid naming, and vocabulary. Reading instruction method was determined from school records and interviews with parents and teachers. Similar to prior findings for individuals with WS, reading ability varied widely, ranging from inability to read any words to reading comprehension at age level. Multiple regression analyses indicated that the primary concurrent predictor of word reading ability was reading instruction method, with a systematic phonics approach associated with considerably better performance than other reading instruction approaches. Phonological processing skills—as assessed by a composite of phonological awareness and verbal short-term memory—also contributed significant unique variance to word reading ability, as did visual-spatial ability. The concurrent predictors of reading comprehension were single-word reading and listening comprehension. These findings indicate that the factors that predict concurrent early word reading and reading comprehension abilities for children with WS are consistent with previous findings for typically developing children and that the Simple View of Reading applies to children with WS. Children with WS benefit strongly from systematic phonics instruction regardless of IQ. Instruction focused on improving listening comprehension is likely to improve reading comprehension, especially as word reading skills increase.

Subjective cognitive decline: opposite links to neurodegeneration across the Alzheimer's continuum.

Subjective memory decline is associated with neurodegeneration and increased risk of cognitive decline in participants with no or subjective cognitive impairment, while in patients with mild cognitive impairment or Alzheimer’s-type dementia, findings are inconsistent. Our aim was to provide a comprehensive overview of subjective memory decline changes, relative to objective memory performances, and of their relationships with neurodegeneration, across the clinical continuum of Alzheimer’s disease. Two hundred participants from the Imagerie Multimodale de la maladie d'Alzheimer à un stade Précoce (IMAP+) primary cohort and 731 participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) replication cohort were included. They were divided into four clinical groups (Imagerie Multimodale de la maladie d'Alzheimer à un stade Précoce/Alzheimer’s Disease Neuroimaging Initiative): controls (n = 67/147, age: 60–84/60–90, female: 54/55%), patients with subjective cognitive decline (n = 30/84, age: 54–84/65–80, female: 44/63%), mild cognitive impairment (n = 50/369, age: 58–86/55–88, female: 45/44%) or Alzheimer’s-type dementia (n = 36/121, age: 51–86/61–90, female: 41/41%). Subjective and objective memory scores, and their difference (i.e. delta score reflecting memory awareness), were compared between groups. Then, voxelwise relationships between subjective memory decline and neuroimaging measures of neurodegeneration [atrophy (T1-MRI) and hypometabolism (18F-fluorodeoxyglucose-PET)] were assessed across clinical groups and the interactive effect of the level of cognitive impairment within the entire sample was assessed. Analyses were adjusted for age, sex and education, and repeated including only the amyloid-positive participants. In Imagerie Multimodale de la maladie d'Alzheimer à un stade Précoce, the level of subjective memory decline was higher in all patient groups (all P < 0.001) relative to controls, but similar between patient groups. In contrast, objective memory deficits progressively worsened from the subjective cognitive decline to the dementia group (all P < 0.001). Accordingly, the delta score showed a progressive decline in memory awareness across clinical groups (all P < 0.001). Voxelwise analyses revealed opposite relationships between the subjective memory decline score and neurodegeneration across the clinical continuum. In the earliest stages (i.e. patients with subjective cognitive decline or Mini Mental State Examination > 28), greater subjective memory decline was associated with increased neurodegeneration, while in later stages (i.e. patients with mild cognitive impairment, dementia or Mini Mental State Examination < 27) a lower score was related to more neurodegeneration. Similar findings were recovered in the Alzheimer’s Disease Neuroimaging Initiative replication cohort, with slight differences according to the clinical group, and in the amyloid-positive subsamples. Altogether, our findings suggest that the subjective memory decline score should be interpreted differently from normal cognition to dementia. Higher scores might reflect greater neurodegeneration in earliest stages, while in more advanced stages lower scores might reflect decreased memory awareness, i.e. more anosognosia associated with advanced neurodegeneration.

Visuospatial working memory abilities and spontaneous sensations perception

Aim: Body awareness arises when attending to and maintaining awareness of visuospatial body representations. By the same token, focussing on representations transfers them to working memory. Body awareness and working memory seemingly rely on similar processes and recruit common parietal areas involved in perception. Therefore, we asked whether visuospatial working memory abilities would define individual differences in the perception of spontaneous sensations (SPS), i.e., bodily sensations perceived in the absence of triggers (e.g., tactile stimulation or movement), when attending to the body. Method: Participants completed two visuospatial working memory tasks to assess various mechanisms: (i) the decay of representations was assessed through a Brown-Peterson task in which the delay between the memorandum presentation and its recall was manipulated, and (ii) the impact of distractors’ interference and cognitive load (i.e., complexity) on recall performances were assessed through a complex span task that required the processing of distractors while maintaining a memorandum. A standard SPS task involving localization and characterization of SPS perceived on the hands was completed afterwards. Results: Low performance due to decay, distractors’ interference and cognitive load in visuospatial working memory was associated with a decrease in the frequency of SPS. Additionally, low performance due to distractors’ cognitive load predicted a decrease in the perception of surface-type sensations, and high performance despite distractors’ interference led to a better perception of SPS on less sensitive areas of the hand. Conclusion: We discuss how visuospatial working memory processes might contribute to body awareness and perceptual distortions of the body.

Effect of Cognitive Variables on the Reading Ability of Spanish Children at Age Seven.

The objective of this study is to determine the contribution made by knowledge of letters, phonological awareness, phonological memory, and alphanumeric and non-alphanumeric rapid automatized naming at the ages of six and seven to the ability of Spanish children to read words at 7 years of age. A total of 116 Spanish-speaking school children took part in the study, from schools located in an average socio-cultural setting, without special educational needs. The reading ability of these pupils was evaluated at the age of seven, and cognitive variables were assessed at 6 and 7 years of age. Descriptive-exploratory analyses, bivariate analyses, and multivariate regressions were performed. The results show that cognitive variables measured at these ages contribute differently to the ability to read words at 7 years of age. Rapid naming does not seem to influence word reading; knowledge of letters no longer influences word reading as children grow older; and phonological awareness and phonological memory maintain their contribution to the explanation of word reading. These results indicate that reading in Spanish depends on different cognitive variables and that this relationship varies according to age. The findings have key educational implications in terms of teaching reading skills and the prevention of specific learning difficulties in Spanish Primary Education.

New Contemplation Upon Subjective Memory Complaints as a Self- Report Criterion for MCI Diagnosis.

Subjective memory complaints are a key component in mild cognitive impairment (MCI) diagnosis. However, studies that examined memory awareness among MCI participants have published contradictory results. One possible explanation for the inconsistent findings could be the disregard from the multidimensional structure of subjective memory. The present study is directed at assessing subjective memory among healthy and MCI participants, referring to three main types of memory: episodic, semantic, and working memory. Participants were 123 adults (aged 50-90). They were divided into two groups, the MCI group, and the control group, according to their objective cognitive performance in RAVL or Mo- CA tests. All participants filled a subjective memory questionnaire, assessing their awareness of episodic, semantic, and working memory. MCI participants estimated their semantic memory as significantly lower in comparison to the estimation of the healthy controls. By contrast, MCI participants showed an overestimation of their episodic memory capabilities compared to the control group. No significant difference was found between groups (MCI and healthy controls) in evaluating their working memory. In addition, for both groups, Pearson's correlation revealed a significant negative correlation between age and semantic memory evaluation. Such correlation was not found for subjective episodic memory. Findings suggest that while people with MCI exhibit poor awareness of their episodic and working memory capabilities, their awareness of their decrease in semantic memory is apparently intact. Therefore, it is suggested that when using the self-report criterion for MCI diagnosis, clinicians should consider the patient's' semantic memory complaints.

Evaluating the rapid automatized naming and arithmetical fluency relationship in Chilean first grade students

Several studies have shown that Rapid Automatised Naming (RAN) is an important reading predictor. However, it has also been found that RAN is a valid predictor of mathematical performance. This study explores the relationship between RAN, counting and arithmetic fluency in Chilean first graders. A total of 102 participants were evaluated with RAN letters, phonological awareness, counting, arithmetical fluency, inhibition and verbal working memory. Results show moderate correlations between RAN and counting with arithmetical fluency. After controlling for the effect of all the variables, RAN still explains a significant variance of arithmetical fluency. Although the nature of the relationship between RAN and arithmetical fluency is multi-componential, our results only confirm the role of working memory when simultaneous counting is considered in the model. Therefore, RAN is not only an important cognitive variable related to reading processes but also a key one for mathematical skills, especially when they involve a fluency component.

Forgetting Unwanted Memories: Active Forgetting and Implications for the Development of Psychological Disorders.

Intrusive memories are a common feature of many psychopathologies, and suppression-induced forgetting of unwanted memories appears as a critical ability to preserve mental health. In recent years, biological and cognitive studies converged in revealing that forgetting is due to active processes. Recent neurobiological studies provide evidence on the active role of main neurotransmitter systems in forgetting, suggesting that the brain actively works to suppress retrieval of unwanted memories. On the cognitive side, there is evidence that voluntary and involuntary processes (here termed “intentional” and “incidental” forgetting, respectively) contribute to active forgetting. In intentional forgetting, an inhibitory control mechanism suppresses awareness of unwanted memories at encoding or retrieval. In incidental forgetting, retrieval practice of some memories involuntarily suppresses the retrieval of other related memories. In this review we describe recent findings on deficits in active forgetting observed in psychopathologies, like post-traumatic stress disorder, depression, schizophrenia, and obsessive-compulsive disorder. Moreover, we report studies in which the role of neurotransmitter systems, known to be involved in the pathogenesis of mental disorders, has been investigated in active forgetting paradigms. The possibility that biological and cognitive mechanisms of active forgetting could be considered as hallmarks of the early onset of psychopathologies is also discussed.

Memory awareness in patients with Major Depressive Disorder

BackgroundSubjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer's Disease (MCI-AD) and healthy controls (HC). MethodsPatients with MDD (n = 47), MCI-AD (n = 43) and HC (n = 45) were assessed with a self-report memory complaints scale (SMCS) and underwent a comprehensive clinical and neuropsychological assessment. A discrepancy score between the Logical Memory delayed recall and the SMCS total score was calculated as a measure of memory awareness. ResultsPatients with MDD (12.5 ± 4.4) and patients with MCI-AD (10.9 ± 4.1) had not significantly different SMCS total scores, whereas HC showed significantly lower scores (4.0 ± 3.0). As much as 74.5% of patients with MDD patients and 65.1% of patients with MCI-AD reported prominent memory complaints, whereas only 4.4% of HC did. Patients with MDD had relatively preserved memory tests, resulting in a higher discrepancy score than both patients with MCI-AD and HC. The SMCS total score correlated positively with depressive symptoms in the 3 groups of participants. ConclusionsPatients with MDD showed inaccurate memory self-awareness as they under-estimated their memory functioning, a pattern distinct from both patients with MCI-AD and HC.

Association between problematic social media use and memory performance in a sample of Lebanese adults: the mediating effect of anxiety, depression, stress and insomnia

BackgroundPsychological factors such as depression, anxiety, stress and insomnia and problematic social media use are able to alter our memories and might have an impact on memory function and retrieval. More studies are needed to better understand the relationship between memory performance and mental health disorders, especially the ones that could be related to problematic social media use. The objective of this study was to evaluate any association between problematic social media use, depression, anxiety, stress, and insomnia vs memory performance among a representative sample of Lebanese people.MethodsThis cross-sectional study, conducted between January and May 2019, enrolled 466 community dwelling participants using a proportionate random sample from all Lebanese governorates. The questionnaire consisted of the following measures: the Memory Awareness Rating Scale (MARS) to assesses views of memory performance, the problematic social media use scale to measure the degree of addiction to social media, the Hamilton depression rating scale and Hamilton anxiety scale to assess depression and anxiety respectively, the Beirut Distress Scale to assess stress and the Lebanese Insomnia sale to assess insomnia. The data analysis was performed using the SPSS software version 25. A linear regression was conducted, taking the memory performance scale as the dependent variable. A mediation analysis was performed to test the effect of problematic social media use on memory performance mediated by depression, anxiety, stress and insomnia.ResultsHigher problematic social media use (Beta = − 0.21) and higher anxiety (Beta = − 0.25) were significantly associated with lower memory performance. The association between problematic social media use and memory performance was partially mediated by anxiety (21.19%) but not depression, stress or insomnia.ConclusionConcerning problematic social media use, a clear correlation was demonstrated in this study linking it to lower memory performances. Future studies should evaluate the possible mechanisms and methods for effective awareness especially towards the younger generation.