Human Papillomavirus Vaccine Awareness Research Articles

Evaluation of patient awareness of 4v and 9v HPV vaccines: A Turkish survey

Background/Aim: The 9-valent (9v) Human Papillomavirus (HPV) vaccine was implemented in Turkey in December 2022 and has just started to be applied. The vaccine is intended to protect against diseases caused by Human Papillomavirus (HPV) Types 6, 11, 16, 18, 31, 33, 45, 52, and 58. Awareness of vaccines in Turkey can be improved through physicians’ and health workers’ efforts, social media and other communication channels. Methods: To guide awareness-raising efforts pertaining to vaccines, we asked our patients who applied for the HPV vaccine at the beginning of 2023 to answer a questionnaire. The survey was prepared to reflect vaccine-related awareness levels of patients applying for the 4v and 9v HPV vaccines. Results: It is noteworthy that the monthly income of patients applying for the vaccine was below the national average. Doubts about the effectiveness of the vaccine and levels of anxiety about its side effects are still high. Less than half of individuals who applied for vaccination received gynecological exams and regular Pap smears. Patients were largely unaware that there were different vaccines against HPV, that the 9v HPV vaccine provides better protection than the 4v HPV vaccine, and that everyone, both male and female, can be vaccinated and can benefit from HPV vaccines. Conclusion: Our findings revealed the social aspects involved in raising levels of vaccine awareness throughout Turkey. Overall, people still have doubts and concerns about HPV vaccination, and they are clearly worried about side effects. Physicians can take these concerns into consideration while providing clinical counseling in order to inhibit the spread of disease.

Assessment of Awareness and Acceptance of the Human Papillomavirus Vaccine among Women in Saudi Arabia: A Community-Based Survey

Background: Globally, cervical cancer represents a major public health concern. The Human Papillomavirus (HPV) vaccine serves as a primary preventive strategy against cervical cancer. This study aimed to assess the HPV vaccine awareness and acceptability (HPVVAA) among women in Saudi Arabia. Methods: This study employed a mixed-methods approach, combining both qualitative and quantitative data to assess HPVVAA among women in Saudi Arabia. A national survey was conducted with a diverse sample of 640 Saudi women, aged 18 to 65, representing both urban and rural areas. Data collection involved structured questionnaires, including both closed-ended and open-ended questions, distributed online and via paper-based self-administration. Descriptive statistics summarized demographic characteristics, while inferential statistics and logistic regression were used to identify associations between variables. Thematic content analysis of the open-ended responses was conducted to explore recurring themes related to awareness, acceptability, and potential barriers. Statistical significance was set at p < 0.05. Ethics approval and written informed consent were obtained prior to participants’ involvement in the study. Results: A total of 640 women participated in the study. The majority of participants were over 50 years old (31.2%), married (45.3%), and held a university or higher educational level (43.8%). Approximately 39.1% of participants had received the HPV vaccine, while 56.3% expressed willingness to accept it. Awareness of HPV and its link to cervical cancer was reported at 78.8% and 62.5%, respectively. The primary source of information (34.4%) was healthcare professionals. Positive attitudes toward vaccinations and favorable perceptions of the HPV vaccine’s safety and efficacy were prevalent among the respondents. Age (p < 0.01; odds ratio [OR]: 1.134; 95% confidence interval [95% CI]: 1.045–1.231) and marital status (p = 0.027; OR: 1.078; 95% CI: 1.007–1.153) were significant predictors of vaccine acceptance. Age was identified as a significant factor that influences awareness (p < 0.001; OR: 1.25; 95% CI: 1.10–1.42). Participants who were one year older were 1.25 times more likely to be aware of the HPV vaccine, with a 95% CI of 1.10 to 1.42 (p < 0.001). Participants with better healthcare access were more likely to be aware of the HPV vaccine (p < 0.001; OR: 1.30; 95% CI: 1.15–1.47). Conclusions: The study found a significant HPVVAA among women in Saudi Arabia. However, there is room for improvement in vaccine uptake, particularly in addressing barriers such as accessibility, affordability, and fear of side effects. Targeted communication strategies and public health initiatives are recommended to enhance HPVVAA and uptake, ultimately contributing to the global goal of cervical cancer prevention and control.

HPV Vaccine Awareness and Uptake Among Sexually Transmitted Infections Clinic Users: A Cross-Sectional Study in Bologna, Italy.

Human Papillomavirus (HPV) infection poses a significant health risk, particularly for high-risk groups such as men who have sex with men (MSM), people living with HIV (PLHIV), and transgender individuals. Despite the availability of effective vaccines, uptake among these groups remains suboptimal due to various social and behavioral barriers (BeSD). A cross-sectional survey was conducted at the Sexually Transmitted Infections (STIs) clinic in Bologna, Italy, from 8 April to 12 April 2024 using a paper questionnaire, investigating HPV vaccine uptake and BeSD factors influencing vaccination decisions. Statistical analyses included descriptive statistics and multivariate logistic regression. Among the 236 respondents, PLHIV and transgender individuals demonstrated lower uptake rates (60.0% and 15.6%) if compared to women under 30 years old (72.7%). Concern about HPV infection varied significantly across groups, with MSM showing the highest worry (48.7%). Perceptions of vaccine safety and access were mixed, influencing vaccination decisions. Multivariate analysis indicated that age inversely correlated with infection worry (OR: 0.94, 95% CI: 0.91-0.98), while being a woman under 30 (OR: 164.0, 95% CI: 17.2-1560.18) or MSM (OR: 3.53, 95% CI: 1.37-9.11) was positively associated with vaccine uptake. The study identifies disparities in HPV vaccine uptake among STI clinic users in Bologna, Italy, emphasizing the need for targeted public health campaigns. These campaigns could engage STI clinics and address awareness, safety perceptions, and access barriers to enhance vaccination coverage among sexual and gender minorities.

Human Papillomavirus Vaccination Awareness and Uptake among Healthcare Students in Japan

BackgroundThe vaccination rate for HPV (Human Papillomavirus) has remained significantly low in Japan because of the administrative suspension of active recommendation. This study investigates the awareness and uptake of the HPV vaccine among healthcare students in Japan following the reinstatement of active recommendation for young women in April 2022. MethodsA web-based survey was administered to 2,567 healthcare students from Okayama and Shujitsu Universities in Japan in July 2023. The survey assessed participants' backgrounds, immunization status, awareness of vaccine recommendations, and knowledge of cervical cancer across various demographics, including sex, academic year, and department (Medicine, Health Science, Pharmaceutical, and Dentistry). ResultsThe response rate was 36.3% (933 students; 181 male, 739 female, and 13 unspecified gender). The overall immunization rate among female students was 55.6%, with higher rates observed in medical (73.8%) and dental (63.0%) students. Awareness of the government's change in vaccine recommendation was notably high among female and senior male students. Over half of the female students (54.7%) reported receiving vaccinations based on their parents' advice. Among those unvaccinated but interested in future immunization, concerns about adverse reactions (47.4%) and challenges in scheduling vaccinations (29.1%) were predominant. ConclusionHealthcare students exhibited a higher HPV vaccination rate than the general population. Ongoing education to improve vaccine literacy is crucial for augmenting HPV vaccination rates in Japan.

Health Behavior Frameworks Describing HPV Vaccine Uptake in Adults: A Scoping Review

Human papillomavirus (HPV) is the most prevalent sexually transmitted disease in the United States, and it has been shown to cause a number of different cancers, namely cervical. Fortunately, there is a highly efficacious vaccine that is available to adolescents and adults up to age 45. Vaccination rates in adults have increased over the years but are still low, especially in men. There is a need to understand HPV vaccine-seeking behaviors in adults to better address their concerns, beliefs, and barriers. The purpose of this scoping review is to provide a synthesis of the current literature on health behavior frameworks that have been used to describe HPV vaccine uptake in adults. This review also covers the socioeconomic barriers of adults getting the vaccine. For this review, 33 articles were found and included. The theory of planned behavior, health belief model, and social cognitive theory were the most commonly seen frameworks in the literature. Theoretical constructs that significantly predicted HPV vaccine behavior across the included studies were social norms, attitudes, perceived behavioral control, perceived benefits, perceived susceptibility, perceived severity, perceived barriers, and self-efficacy. Major socioeconomic factors that were described were provider recommendation, knowledge, age, gender, race, awareness, and marital status. This information is critical for public health efforts to better target the adult population with HPV vaccine information and awareness. It is also necessary for providers to better understand patients and their potential barriers to getting the HPV vaccine.

Factors affecting human papillomavirus vaccine acceptance among parents of Primary 4 to 6 boys and girls in Hong Kong.

Human papillomavirus (HPV) poses a substantial but underestimated healthcare burden in Hong Kong. This study investigated factors affecting parental acceptance of HPV vaccination after the introduction of an immunisation programme for primary school girls. We assessed parental perceptions and related factors concerning HPV vaccination for both boys and girls. We conducted a cross-sectional survey between December 2021 and February 2022 among parents of Primary 4 to 6 students in Hong Kong. Our self-administered online survey collected data regarding socio-demographic characteristics, awareness and knowledge of HPV vaccination, attitudes towards HPV vaccination, and acceptance of HPV vaccination. Characteristics were compared between boys' parents and girls' parents. Factors associated with vaccine acceptance were analysed by multivariate logistic regression. We observed high awareness of HPV vaccination among boys' parents and girls' parents; however, they demonstrated relatively poor knowledge of HPV and the HPV vaccine. An alarming low HPV vaccination uptake rate was also observed. Attitudes towards the HPV vaccine were similar between parent groups. A majority of parents believed that the HPV vaccine was safe and effective in preventing infection. Parents of boys showed lower HPV vaccine acceptance. Factors associated with acceptance differed between parent groups. High awareness of HPV and HPV vaccine is predictive of vaccine acceptance. Boys' parents are less likely to accept HPV vaccination and emphasis should be placed on addressing potential HPV vaccine hesitancy in this group. Public education should also aim to raise awareness of government vaccination programme, and implementation of catch-up vaccination programme to school children beyond primary school should be considered.

Awareness and knowledge of human papillomavirus, vaccine acceptability and cervical cancer among college students in Saudi Arabia

ABSTRACT Human papillomavirus (HPV) is the most prevalent sexually transmitted infection among teenagers and young adults. HPV vaccination and screening are vital preventive measures to reduce the incidence of HPV-related complications, including cervical cancer. Given the rising global incidence of cervical cancer, understanding the factors influencing awareness and knowledge among young adults in Saudi Arabia is essential for developing effective prevention strategies. This study investigates the levels of awareness, knowledge, and vaccine acceptability regarding HPV and cervical cancer among college students in Saudi Arabia. A cross-sectional study was conducted between May and September 2023 among 442 students in Saudi Arabia using a structured questionnaire to assess their knowledge and awareness of HPV, HPV vaccination, and cervical cancer. Multivariate logistic regression analysis was employed to examine the associations between predictor and dependent variables. Among participants, 54.1% were aware of HPV, and 66.5% had heard of cervical cancer. However, only 17% correctly identified HPV16 and HPV18 as high-risk genotypes for cervical cancer. Awareness of the HPV vaccine was reported by 36.2% of participants, with just 10% having received the vaccine. Female students exhibited significantly higher knowledge levels than males (p = .018). The primary barrier to vaccination was identified as a lack of education and awareness (80.1%). The study highlights a significant gap in knowledge and awareness regarding HPV, its vaccine, and cervical cancer among college students in Saudi Arabia. Targeted educational programs and awareness campaigns are essential to enhance understanding and promote preventive practices, including vaccination and regular screening.

Roadmap to Success: Illustrating Insights from a KAP Study on Cervical Cancer Prevention and HPV Vaccination

Introduction Cervical cancer is a public health challenge in low- and middle-income countries, with India ranking among the highest in cervical cancer burden. The World Health Organization (has set ambitious targets for cervical cancer elimination by 2030, emphasizing the importance of human papillomavirus (HPV) vaccination and screening. In response, the National Technical Advisory Group of Immunization recommends the introduction of HPV vaccination for all eligible girls aged 9 to 14 years in India under the Universal Immunization Program. However, successful implementation requires both vaccine availability and changes in health care providers' knowledge, attitudes, and practices (KAP) regarding cervical cancer prevention and HPV vaccination. Methodology This study aims to assess KAP among clinicians regarding cervical cancer and HPV vaccination. A cross-sectional survey collected responses from 451 practicing gynecologists and medical practitioners across 15 states of India. The questionnaire sought insights into patient inquiries, information sources, awareness levels, methods of patient education, and common myths and misconceptions. Results Results indicate a high prevalence of patient inquiries about cervical cancer and the HPV vaccine, emphasizing the need for accurate and accessible information. While doctors were generally knowledgeable, misconceptions persisted among patients, including beliefs about low risk, inevitability of cervical cancer, and concerns about vaccine safety. Doctors primarily relied on verbal communication for patient education, suggesting potential for utilizing digital platforms and visual aids to enhance outreach. Insights Insights from doctors underscored the importance of addressing misinformation and leveraging various communication channels, including social media, posters, and celebrity endorsements, to improve awareness and acceptance of vaccination. Disparities in vaccine availability and administration rates highlighted the need for targeted interventions to ensure equitable access. Limitations Limitations of the study included its cross-sectional design and reliance on self-reported data, which may introduce bias. However, findings suggest a need for ongoing medical education and collaboration with stakeholders to drive awareness and acceptance of HPV vaccination. Conclusion In conclusion, while gynecologists and medical practitioners demonstrate adequate KAP regarding cervical cancer prevention, there is room for improvement in patient education and communication strategies. Refining educational materials and strengthening communication channels would enhance awareness and reduce cervical cancer burden.

Abstract A123: Awareness of human papillomavirus (HPV) and its vaccine and telehealth: Results from the Health Information National Trends Survey (HINTS) 6, 2022 in the United States

Abstract Background: Human Papillomavirus (HPV) vaccination is essential to prevent occurrences of a variety of HPV associated cancers. The awareness of HPV and its vaccine could be associated with the use of telehealth. The aims of this study were to examine the association between awareness of HPV and HPV vaccine with receiving telehealth for health care within the past year. Methods: Data from the Health Information National Trends Survey (HINTS) 6 (N=5,887) were utilized. Dependent variable was awareness of HPV and HPV vaccine. The independent variable was those who received care from a doctor or health professional using telehealth. Weighted multivariable logistic regression was performed to determine association of awareness of HPV and its vaccine with receiving healthcare using telehealth while adjusting for age, gender, race, education, and census region. Results: The study sample consisted of 68.28% awareness of HPV and 63.47% awareness of HPV vaccine. After controlling for covariates, we found those who were aware of HPV and HPV vaccine have received telehealth care (aOR=1.40, 95%CI:1.11-1.78; aOR= 1.40, 95%CI:1.09 -1.80), respectively. In the adjusted model, the awareness of HPV for being female (aOR=2, 95%CI:1.60-2.48) and college graduates (aOR=3.80, 95%CI: 2.59-6.56). In the adjusted model, the awareness of HPV vaccine for being female (aOR= 2.68, 95%CI:2.13-3.36) and college graduates (aOR=4.68,95%CI:2.77-7.91). HPV and HPV vaccine awareness, Non Hispanic Whites had significantly higher adjusted odds compared to other race/ethnicity groups. Conclusion: Hence public health programs could be directed to promote use of telehealth to increase awareness of HPV causing cancers, reduce stigma associated with vaccination, boost healthcare recommendation and uptake of HPV vaccination considering socio demographic factors. Citation Format: Manali Desai, Iman Igab, Ogochukwu Ezeigwe, Devesh Malgave. Awareness of human papillomavirus (HPV) and its vaccine and telehealth: Results from the Health Information National Trends Survey (HINTS) 6, 2022 in the United States [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A123.

Abstract A109: Knowledge of HPV vaccination and HPV-associated cancers among Arab- Americans

Abstract Background: Human papillomavirus (HPV) includes oncogenic subtypes linked to the majority of head and neck and genitourinary cancer cases. Despite suggestions to boost HPV vaccine uptake by increasing HPV awareness, public understanding remains suboptimal. This is especially noted among cultural and ethnic minorities, with limited literature addressing this gap. This study evaluated awareness of HPV and HPV-associated cancers among Arab Americans. Methods: This was a cross-sectional study conducted between March and July 2023. Surveys were provided in both English and Arabic based on participants' preferences. Recruitment took place at various venues such as fairs, functions, and religious and cultural gatherings, targeting self-identifying Arab Americans residing in Michigan. Dependent variables included participants' awareness (yes/no/don’t know) of HPV, HPV vaccine, and HPV association with specific cancers (cervical, penile, anal, vulvar, vaginal, and oropharyngeal). Independent variables included age, gender, level of education, frequency of doctor and dentist visits in the past year, number of oral and vaginal sexual partners, and cigarette use. Descriptive statistics were used to analyze survey responses. Multivariable logistic regression models estimated the associations between HPV awareness and sociodemographic factors. Results: A total of 289 individuals were included in the study, of whom almost half (47%) were not aware of HPV and the HPV vaccine. Awareness of HPV association with specific cancers were as follows: 50.5% for cervical cancer, 48.4% for vaginal cancer, 42.4% for vulvar cancer, 41.5% for penile cancer, 38.9% for anal cancer, and 37.9% for mouth/throat cancer. In multivariable logistic regression models, compared to females, males were less likely to be aware of HPV vaccine (OR 0.37, 95% CI 0.19 – 0.72); or of HPV association to cervical (OR 0.38, 95% CI 0.19-0.73) and anal (OR 0.49, 95% CI 0.26-0.94) cancers. Similarly, respondents who had lower education were less likely to be aware that HPV could cause cervical (OR 0.31, 95% CI 0.14-0.69), anal (OR 0.30, 95% CI 0.13-0.69), as well as mouth/throat (OR 0.34, 95% CI 0.14-0.80) cancers compared to those with college degrees. Conclusions: Awareness of HPV, the vaccine and related cancers among Arab Americans are suboptimal. Being female or having a college education correlates with greater awareness of HPV and HPV-associated cancers. This underscores the necessity for targeted interventions to improve awareness among this population. Future interventions should focus on increasing knowledge of how HPV can cause several cancers and how those cancers could be prevented through HPV vaccination. Citation Format: Eric Adjei Boakye, Nada Al-Antary, Reem F Siddiqui, Marissa Gilbert, Lamis Fakhoury, Mrudula Nair, Milkie Vu, Farzan Siddiqui. Knowledge of HPV vaccination and HPV-associated cancers among Arab- Americans [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A109.

Abstract A116: Cervical cancer awareness, knowledge, and attitudes in young adult students on a Northern California college campus

Abstract Cervical cancer is the fourth most common gynecological malignancy in women worldwide. Human papillomavirus (HPV) is the primary cause of cervical cancer, with increased risk associated with select serotypes HPV 16 and 18. This study assesses cervical cancer awareness, knowledge of HPV, and attitudes towards vaccination among a convenience sample of San Francisco State University (SFSU) students. Despite the availability of effective HPV vaccines and associated cervical cancer prevention, vaccine uptake remains relatively low which may be due to various factors, including lack of awareness and vaccine knowledge. A convenience sample survey assessing cervical cancer awareness, behaviors and attitudes about HPV vaccine was administered to students on the San Francisco State University campus. The data was collected anonymously, via QR code. Participants received a $10 Target gift card. At completion of the survey, a 5x7 information card about Cervical Cancer and HPV vaccines, developed by and for college students, was distributed to participants. A total of 100 students completed the survey. Participants average age was 23-24 years old; 60% of participants identified as female; 34% as male. The vast majority of participants were aware of cervical cancer. Among 60 female respondents, 25 (42%) reported having had a pap smear, but a larger proportion had not. Of the female participants over age 21 years old, 12 out of 62 had never had a pap smear. 39% of respondents were not aware of the HPV vaccine and its relationship to cervical cancer prevention. There was a large difference in HPV vaccine awareness by gender and age. Of the 60 female respondents, 20 had reported being unaware of the HPV vaccine, while 17 of the 34 male respondents also reported being unaware. At completion of the survey, two-thirds of respondents reported a plan to receive a pap smear as recommended. 16% said they will not, and 21% were unsure. Our survey set out to understand the distribution of knowledge, awareness, attitudes and behaviors about cervical cancer and HPV vaccination on the SF State college campus. We found that most students on our campus are aware of cervical cancer. However, a small proportion of participants eligible for pap smears have yet to undergo the procedure. Our research also revealed that there is a lack of understanding regarding the importance of HPV vaccination, with significant differences in awareness by gender and age. This study underscores the need for targeted educational initiatives on cervical cancer awareness, knowledge, and attitudes towards HPV and its vaccine. To improve awareness and preventive actions, we can; increase the efforts to educate the public about the importance of HPV vaccinations and regular Pap smears and improve access to vaccination and screening services. Addressing gaps in knowledge and negative impressions of HPV vaccine can lead to the ultimate eradication of CC as we know it. Citation Format: Elissa I. Sanders, Kim F. Rhoads, Suzana Beyene. Cervical cancer awareness, knowledge, and attitudes in young adult students on a Northern California college campus [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A116.

Knowledge and awareness of human papillomavirus (HPV) influence HPV vaccination uptake among the catch-up generation in Japan

IntroductionDespite its importance for young women, the human papillomavirus (HPV) vaccination coverage remains low in Japan. Previous studies have examined behaviors related to HPV catch-up vaccination. Uniquely, this study aimed to investigate perceptions and factors influencing vaccination coverage among female university students in the catch-up program, focusing on both medical and non-medical undergraduates. MethodsA web-based survey was conducted at Kochi University from January 16 to February 13, 2023, targeting female students born between April 2, 1997, and April 1, 2006. The survey collected demographic data and assessed knowledge of HPV infection, cervical cancer, and preventive measures. Chi-square tests and logistic regression analyses were used to identify differences between vaccinated and unvaccinated groups as well as factors related to HPV vaccination. ResultsOf the 310 participants, 39.0 % were vaccinated against HPV, 35.2 % were freshmen, and 75.2 % were in medical science programs. HPV vaccination was significantly associated with being in upper years of university (OR = 3.78–42.83), studying medical sciences (OR = 1.93), undergoing cervical cancer screening (OR = 4.04), and receiving free vaccination vouchers (OR = 2.03). ConclusionKnowledge and awareness of HPV and cervical cancer significantly contribute to higher vaccination uptake in the generation receiving catch-up vaccinations. Tailoring information and distributing free vaccination vouchers could enhance HPV vaccination rates and awareness in this group.

Effect of health education on the awareness of human papillomavirus infection among undergraduate students of a health sciences university – An interventional study

BACKGROUND: Human papillomavirus (HPV) infection is a significant public health concern associated with various cancers. Despite available vaccines, knowledge gaps persist among healthcare students, impacting vaccine uptake. This study aimed to assess the impact of an educational intervention on health-care students’ knowledge, attitudes, and practices regarding HPV infection and vaccination. Furthermore, the study aimed to assess the potential barriers to vaccination. METHODOLOGY: A pre- post-interventional study was conducted among 656 undergraduate healthcare students over a period of 1 year to assess baseline knowledge, attitudes, and practices related to HPV infection and vaccination using a self-structured validated questionnaire. Following this, an educational intervention, in the form of an interactive PowerPoint presentation, was conducted. Moreover, posttest surveys were administered 1 month after the intervention. Statistical analyses were performed using IBM SPSS v23.0. RESULTS: The median age of the students in the study was 21 years. Pretest surveys revealed knowledge gaps and misconceptions among participants with a knowledge score of 10.59 ± 6.58 (mean ± standard deviation [SD]), attitude score of 1.31 ± 1.944 (mean ± SD) and pretest willingness to receive the vaccine was 6.4%. Whereas, postintervention, significant improvements were observed in knowledge, attitudes, and practices regarding HPV infection and vaccination, with a mean knowledge score of 25.82 ± 8.34 and a mean attitude score of 3.84 ± 4.259. Practices also improved, with more participants expressing readiness to receive (75.9%) and advocate for vaccination. Moreover, the study demonstrated the potential barriers to vaccination as lack of awareness, nonavailability, and cost of the vaccine. CONCLUSION: Targeted educational interventions effectively improved HPV vaccination awareness and acceptance among health-care students. These findings contribute to public health efforts in HPV prevention and control.

Three-year questionnaire study on human papillomavirus vaccination targeting new female college school students: Follow-up to a 2021 report to reveal the impact of a policy change in Japan.

The purpose of this study was to examine the trend in human papillomavirus (HPV) vaccination rates in Japan before and after a policy change in 2022, involving resumption of active recommendation and start of catch-up vaccination. From 2021 to 2023, a web-based questionnaire survey was administered to newly enrolled female college students in Yokohama, Japan. The questionnaire included items such as age, HPV vaccination status, HPV vaccine awareness, and awareness of catch-up vaccination. We compared knowledge about the HPV vaccine and cervical cancer in 2021 and 2023, before and after resumption of the national vaccination program. The HPV vaccination rates were 5.4% in 2021, 7.5% in 2022, and 35.3% in 2023, with a significant upward trend (p < 0.001). A similar upward trend was observed for HPV vaccine awareness (p < 0.001). Comparing 2022 and 2023 after the start of catch-up vaccination, there was no significant difference in awareness of catch-up vaccination (p = 0.669), but there was a significant increase in awareness of free vaccination tickets (p < 0.001). After resumption of the national vaccination program with adoption of the catch-up vaccination program, there was no difference in knowledge of cervical cancer, but there was a difference in knowledge of the HPV vaccine. Although the HPV vaccination rate has increased after the policy change, it has not recovered to the level before the suspension of active recommendation. It is important for healthcare providers and school educators to actively communicate the safety and effectiveness of the HPV vaccine.

Sociodemographic determinants of HPV vaccine awareness, uptake, and intention among parents of adolescents in France 2021-22

ABSTRACT Human Papillomavirus (HPV) vaccine coverage was <50% in France in 2022 and even lower among socially disadvantaged populations. We aimed to evaluate socio-demographic determinants of HPV vaccine awareness, uptake, and intention among parents of adolescents, and related attitudes and knowledge items. Parents of adolescents attending middle schools across France, who participated in a randomized trial responded to an anonymous baseline survey, conducted between November 2021 and February 2022. We used logistic regression models adjusting for a child’s age and sex to explore sociodemographic determinants (including at-home multilingualism, occupational categories, local deprivation index and urbanity) of HPV vaccine awareness, uptake, and intention. Among the 1889 participants from 61 schools, parents working as factory workers/farmers had significantly lower odds of vaccine awareness compared to executives/professionals, both if they reported (OR = 0.07; 0.03–0.15) or not (OR = 0.20; 0.11–0.36) speaking also another language than French at home. Parents in lower occupational categories with multilingual families were less likely to have the intention to vaccinate their child (OR = 0.19; 0.07–0.56). Recent physician visit or vaccine offer was strong positive determinants of awareness, uptake and intention. A substantial gradient across occupational categories was observed for attitudes and knowledge around HPV vaccine usefulness, safety, and accessibility. This study confirms the disparities on HPV vaccine uptake in France and provides insight into mechanisms of social disparities in HPV vaccine awareness, access and intention.

The Impact of an Educational Program on the Awareness and Knowledge of Human Papilloma Virus (HPV) Vaccine Among Secondary School Girls in Saudi Arabia.

The objectives were to assess the effectiveness ofthe educational program in enhancing students' understanding of thehuman papillomavirus (HPV) vaccine, correcting misconceptions, and increasing overall awareness. Additionally, the study aimed to identify factors influencing knowledge improvement and willingness to be vaccinated against HPV, including prior knowledge, information sources, session attendance, and school type. In this study, 148 participants were enrolled from secondary schools in Saudi Arabia, and data were collected through pre- and post-educational session assessments, logistic regression analyses, and qualitative investigations. Educational sessions focused on key aspects of the HPV vaccine, including its preventive benefits, administration details, and side effects, tailored to address common misconceptions and enhance understanding among students. The study revealed significant improvements in students' knowledge post-educational sessions, particularly in key areas such as cervical cancer prevention, gender recommendations, vaccine administration, and side effect awareness. Prior knowledge, information sources, session attendance, and school type significantly influenced knowledge enhancement and willingness to be vaccinated against HPV. The qualitative analysis provided additional insights into challenges, perceptions, and misconceptions surrounding HPV vaccination, underlining the significance of targeted education and cultural sensitivity in promoting vaccination uptake. The findings underscored the effectiveness of the educational intervention in enhancing HPV vaccine awareness, dispelling myths, and fostering informed decision-making among Saudi Arabian adolescent populations. The study emphasizes the critical role of tailored educational programs in correcting misconceptions, promoting accurate knowledge, and ultimately increasing vaccination acceptance for improved public health outcomes and disease prevention efforts. Ongoing efforts are essential to sustain and expand educational initiatives to enhance HPV vaccine understanding and adolescent uptake.

Inequities in human papillomavirus vaccination among children aged 9–14 years old under constrained vaccine supply in China

BackgroundInequities in access to human papillomavirus (HPV) vaccine are becoming a growing critical issue globally. Few studies investigate the factors determining HPV vaccine uptake disparities when vaccine supply is constrained, especially in low- and middle-income countries. The aim of this study was to investigate inequities of HPV vaccination and related factors under the constrained vaccine supply in China.MethodsA cross-sectional survey was conducted in a developed eastern coastal province and a developing western one in China between November and December 2022. Employing multistage stratified cluster random sampling, the study collected data from parents of children aged 9–14. Mixed-effects logistic regression models with school units as random effects were used for analysis.ResultsFrom 4,127 eligible parents (as vaccine decision makers for girls), 1,346 (32.6%) intended to vaccinate their daughters against HPV, of which 836 (62.1%) attempted to schedule a vaccination appointment. Only 16.4% succeeded in booking an appointment. More than half of the intended parents expected the imported 9-valent HPV vaccine. There were significant disparities in HPV vaccine awareness, intention, and vaccination behavior across educational, income, geographic, ethnic, gender, and health literacy levels. Vaccine awareness and intentions were higher among parents with higher socioeconomic status; however, girls from lower socioeconomic families were more likely to receive the HPV vaccine and had a higher domestically produced vaccination rate. Significant disparities exist in vaccination intentions and actual vaccination behaviors, primarily due to large supply constraints of the HPV vaccine.ConclusionsSustained health education campaigns are needed to raise awareness of the HPV vaccine, improve health literacy, and decrease over-preference for the 9-valent HPV vaccine. A mother’s HPV vaccination behavior was positively associated with increased intention and actual vaccination behavior for her daughter. This study advocates for complementary cervical cancer prevention programs targeting both mothers and daughters.

Knowledge About Cervical Cancer and Awareness About Human Papillomavirus Vaccination Among Medical Students at the Northern Border University, Arar, Kingdom of Saudi Arabia.

Objectives To evaluate the knowledge and awareness about cervical cancer and human papillomavirus (HPV) vaccination among medical undergraduates at Northern Border University. Methods It was a cross-sectional studydoneon students selected conveniently from the College of Medicine, Northern Border University, Arar. The data were collected regarding knowledge about HPV infection and vaccine awareness using a validated questionnaire. Results A total of 200 students responded to the questionnaires, with 104 (52%) being male students and 120 (60%) being clinical years of MBBS. The mean knowledge score was 17.12 ± 2.73 out of 24, which was labeled as moderate knowledge about cervical cancer and HPV. Almost two-thirds of the students responded correctly to the etiology and risk factors of cervical cancer, whileonly half of the students knew the correct screening intervals for cervical cancer.The awareness of studentsabout the HPV vaccine was deficient, andthe mean score was estimatedto be 4.20 ± 0.79 out of nine. Female students and students in clinical years showed significantly better understanding and awareness about cervical cancer and its vaccine and showed greater vaccine acceptability as compared to male students and students in preclinical years. Conclusion The present study shows moderate knowledge about cervical cancer but deficient awareness of medical students about the HPV vaccine. However, the students were willing to get educated about cervical cancer and its vaccine and showed a favorable opinion towards vaccinating the schoolgirls and educating their patients as future physicians. The information can be considered a benchmark on knowledge and awareness levels and can be utilized to modify medical curricula and develop efficient awareness programs.

A feasibility study assessing knowledge, vaccine hesitancy, and completion rates of free HPV vaccination in low-income uninsured adults.

Human Papillomavirus (HPV) vaccination rates remain low in the U.S., particularly among minorities and low-income, uninsured patients. We report preliminary data on a pilot study program providing education and free HPV vaccination at a clinic serving low-income uninsured adults. From October 2020 through October 2022, we assessed HPV vaccination knowledge, awareness, and prevalence of hesitancy towards receiving the vaccine among low-income uninsured patients age 18-45. The Parents Attitudes about Childhood Vaccines (PACV) survey was modified and used to evaluate vaccine hesitancy. An educational video on HPV was shown to patients declining vaccination. 43 patients were enrolled. 69.8% had heard of the HPV vaccine and 85.7% were non-hesitant based on PACV scores of 0-49. Black participants had a statistically significant higher PACV score (more hesitant) than White participants. Familiarity with the HPV vaccine correlated with lower PACV scores. Only 27% completed all three HPV vaccine doses. The availability of an education program together with free HPV vaccination are not sufficient to achieve adequate vaccination rates in low-income, uninsured adults. Innovative, culturally sensitive education and supportive interventions, in addition to access to free HPV vaccination, are warranted in order to improve vaccination rates in this underserved population.

Awareness of HPV vaccine and its socio-demographic determinants among the parents of eligible daughters in Bangladesh: A nationwide study

BackgroundVaccination against Human papillomavirus (HPV) is recommended to avoid HPV infections and its associated diseases, including cervical cancer. However, there is no awareness study among Bangladeshi population. Hence, this nationwide study was conducted to explore HPV vaccine awareness and its determinants among parents of eligible adolescent girls. MethodsThis study was conducted among the parents of daughters aged 9–15 years from 42 out of 64 randomly selected districts of Bangladesh between June 28 to August 2, 2023. A multistage sampling method was used to enroll 2151 study participants from all eight divisions of Bangladesh. A semi-structured questionnaire was used for face-to-face interviews in this study. The statistical software Stata (Version 17) was used for statistical analyses. ResultsThe average age of the participants was 38.18 (±5.86) years. Only 22.32 % of the participants were aware of the HPV vaccine. Every additional year of age increased the likelihood of being aware of the HPV vaccine by 3 % (AOR: 1.03; 95%CI: 1.00–1.06). Participants residing in the urban area had 3.56 times higher odds of awareness than rural and semi-urban people. Businessmen and housewives had 60 % (AOR: 0.40; 95 % CI: 0.22–0.69) and 77 % (AOR: 0.23; 95 % CI: 0.16–0.33) lower odds in comparison to job holders. The lower-income group exhibited significantly higher odds of awareness (AOR: 0.25, 95%CI: 0.16–0.39) compared to the middle and the higher-income group. Participants who never went through routine health check-ups had 77 % lower odds of being aware than those who availed of regular routine check-ups (AOR: 0.23; 95%CI: 0.16–0.34). ConclusionAwareness of the HPV vaccine among the general population of Bangladesh is very low. Age, residence, occupation, monthly income, and routine medical check-ups were associated with HPV vaccine awareness. A nationwide awareness campaign would increase this awareness level among the Bangladeshi population, especially among the parents of daughters.