The cardiovascular system of humans and animals is a complex of organs that ensure the supply of all parts of the body (with a few exceptions) with necessary substances and remove waste products. It is the cardiovascular system that provides all parts of the body with the necessary oxygen and is the basis of life. Currently, research into the problems of maintaining an optimal level of well-being, assessing the functional state and improving the adaptive capabilities of animals continues to be relevant. A significant direction in this area is the study of the activity of the cardiovascular system (CVS), the parameters of which are characterized by high reactivity and an important role in the implementation of adaptive mechanisms of the animal body. Cardiovascular diseases remain the leading cause of death in most cases in both humans and animals. In many ways, the solution to this problem depends on timely and effective diagnosis of changes in the myocardium. The main goal of the research work is to establish indicators of cardiohemodynamic values and analyze them in horses. In our studies, to measure and further analyze indicators of central and peripheral hemodynamics, we used a hardware-software complex for non-invasive study of central hemodynamics using the method of volumetric compression oscillometry KAP TsGosm-“Globus” (oscillometric analyzer of blood circulation indicators). In horses, during the study, average numerical values of myocardial-hemodynamic parameters were obtained: different types of blood pressure, vascular characteristics and indicators of cardiac activity. Mathematical analysis of hemodynamic indicators established the values of cardiohemodynamic indicators. In this regard, it is advisable to include the assessment of these parameters in the basic set of methods for diagnosing heart diseases in horses. The study of the cardiovascular system is of great importance in veterinary treatment and prophylactic work.