Average Number Of Pregnancies Research Articles

Features of gynecological status and concomitant morbidity in menopausal women with resistant rheumatoid arthritis and obesity

Oftentimes, women with RA experience remission during pregnancy. The beneficial effect of pregnancy on the RA course is associated with a specific hormonal status, including high levels of estriol and progesterone that have known anti-inflammatory effects. After childbirth, decreased endogenous production of steroids can trigger the onset or exacerbation of RA.Objective. Studying of the characteristics of the gynecological status and concomitant extragenital diseases in postmenopausal women with rheumatoid arthritis (RA) depending on the presence of obesity.Materials and methods. 394 postmenopausal women with RA (diagnosed according to ACR/EULAR 2010 criteria) were included. By decision of the medical commission, all patients were approved for therapy with genetically engineered biological drugs and/or JAK kinase inhibitors. Before inclusion in the study, all patients had a detailed medical history, an allergic history, registered comorbidities, and a physical and laboratory-instrumental examination. Depending on the BMI values, the study participants were divided into groups. Group A included 103 obese patients of any severity (BMI ≥ 30 kg/m2). Group B included 291 women with BMI <30 kg/m2. Patients with an inflammatory process were found to have groups of inflammation by age and duration of RA (p > 0.05).Results. In patients of group A, more often than in patients of group B, comorbidities were detected: hypertension (p < 0.0001), coronary heart disease (p = 0.03), history of “vascular accidents” (p = 0.0009), especially acute cerebrovascular accident (p = 0.004), type 2 diabetes mellitus (p = 0.0005), which manifest themselves over the age of 45, that is, during the perimenopause. When correcting the gynecological history data, he draws attention to the fact that group A patients are more likely to operate surgically and on the pelvic organs: more had the uterus removed (p = 0.002) or ovarian resection was performed (p < 0.0001), and the frequency of surgical menopause in group A was higher than in group B (p = 0.0009). The debut of RA on average chronologically coincided with the onset of menopause (p = 0.01). At the same time, in the average age of the onset of menopause, it is rare (p > 0.05). The number of women who had a history of pregnancy, childbirth, miscarriages and abortions in the groups were repeated (p > 0.05). But in group A, the average number of pregnancies (p = 0.003) and abortions (p = 0.004) per woman was higher than in group B.Conclusion. The results of the study revealed the identification of clinical manifestations of inflammation and the severity of rheumatoid arthritis, depending on the presence of concomitant obesity in postmenopausal women, as well as a rarer occurrence of osteoporosis in women with RA and concomitant obesity.

Investigation of Psychosocial Health and Depression Levels of Pregnancy

Objective: The present study was conducted to examine the relationship between psychosocial health and depressive symptom levels of pregnant women.Methods: The data of 150 pregnant women who were followed up in the Family Healthcare Center were collected by face-to-face interview. The data were collected with study specific Personal Data Form, the Psychosocial Health Assessment in Pregnancy Scale (PHAPS), and Beck Depression Inventory (BDI).Results: The mean age of the pregnant participants was 27.49±5.69 years, and the mean marriage duration was 6.21±5.33 years and average number of pregnancies 2.50±1.58. Of the pregnant women participating in the study, 26.0% were in the first trimester, 34.7% were in the second trimester, and 39.3% were in the third trimester. The total mean score of the PHAPS during the pregnancies of the women was 2.06±0.6 and their psychosocial health status was poor. It was found that 23.3% of the pregnant women had mild, 8.7% had moderate, and 0.7% had severe depression symptoms.Conclusion: Negative and moderately significant relations were detected between better psychosocial health status and depression during pregnancy.

Determination of Risk Factors Associated with the Development of Cervical Cancer in Mirpur, AJK

Background: Cervical cancer is an important public health issue. Numerous factors are associated with the development of cervical cancer. Aim: To understand various contributory and risk factors associated with the development of cervical cancer in our area. Study design: Descriptive cross-sectional study. Duration and place of study: Mohi-ud-Din Islamic Medical College, Mirpur AJK from October 2021 to March 2022. Methods: Volunteering women were included in the study. A pre-tested questionnaire was used to collect data. The proforma included demographic and epidemiological information as well as about the various risk factors which were associated with the development of cervical carcinoma. A detailed medical history was taken and special emphasis was placed on the gynecological history including obstetrical and menstrual history as well as sexual and reproductive history together with contraception usage. Results: There were 753 study participants and their mean age was 56.80±10.51years. The mean age of first sexual intercourse was 17±2.80 years and the average number of pregnancies was two. About 14.61% of our study population was smoker. Hormonal contraception was practiced by 64.01% while 11.29% preferred intra-uterine contraceptive device as a mode of contraception. The prevalence of sexually transmitted diseases was 10.49% and out of these diseases, condylomatosis accounted for 05.84% of cases while syphilis and human immunodeficiency virus were responsible for 04.78% of cases collectively. Conclusion: There are various risk factors associated with the development of cervical cancer. Most important of them are younger age at marriage or sexual activity, use and duration of contraception usage and smoking. There is a need to arrange awareness campaigns among masses to raise awareness about the risk factors and also about the benefits of early screening so as to prevent the development of cervical cancer. Keywords: Human Papilloma Virus, Risk Factors, Cervical Cancer, Women, Contraception, Screening

Abstract 15303: Maternal Features for Live Births in Fontan Patients

Introduction: As the population of women with congenital heart disease with prior Fontan palliation (PFPs) increases, doubling in size over the next 20 years, there will be a concordant need for multidisciplinary obstetrics care. There is an increased prevalence of miscarriage, maternal and fetal complications including arrhythmias, heart failure, premature birth, and neonatal death. We sought to review our single center experience in the context of an established cardio-obstetrics multidisciplinary team. Methods: Single-center retrospective cohort study of PFPs with live births who received care at our cardio-obstetrics clinic. A chart review was performed to identify maternal characteristics as well as fetal outcomes. Descriptive statistics were calculated using R Studio Statistical Software version 1.2.5033.Result: Ten women with PFPs and live births were identified. None had more than one live pregnancy. The average number of pregnancies was 2 (range 1-6). The mean gestational age was 31.2 weeks (range 23-37). Five patients were primigravida. Six of the pregnancies were planned and eight received preconception counseling. Baseline NYHA was 50% class I and 50% class II. The most common maternal comorbidity in patients with a live pregnancy was atrial arrhythmia, and the most common pre-pregnancy medication was warfarin. Prematurity, low birth weight, and associated comorbidities (see table 1) were common in this population. The average birthweight was 1,589g (range 460g-2210g). Indication for delivery was more commonly obstetric than maternal concern. No maternal strokes, thromboembolic events, cardiac arrests, maternal or infant deaths and rehospitalizations were noted. Conclusion: Maternal and fetal complications in mothers with PFP are common. A multidisciplinary approach in a specialized cardio-obstetrics clinic has the potential to improve outcomes. Larger cohort and long term outcomes are needed in this patient population.

Clinical analysis of high-intensity focused ultrasound (HIFU) combined with hysteroscopy-guided suction curettage (HGSC) in patients with cervical pregnancy

Objective To evaluate the effectiveness of high-intensity focused ultrasound (HIFU) combined with hysteroscopy-guided suction curettage (HGSC) in treating cervical pregnancy. Materials and methods This is a retrospective study. Seven patients with cervical pregnancy who visited the Third Xiangya Hospital of Central South University from January 2015 to December 2020 were enrolled in the current study. All seven patients were treated with HIFU under conscious sedation. All of them underwent HGSC at an average of 2 ± 1 days (range: 1–3 days) after HIFU. Before the therapy, the patient's clinical characteristics were collected, including duration of amenorrhea, gravidity and parity, the patient history of cesarean section and miscarriage, and the size of the gestational sac. The levels of β-hCG and hemoglobin in serum were also reviewed. To assess the clinical outcomes of this combined treatment, the suction time of HGSC, bleeding volume, the clearance time of β-hCG, and the time with returning of menstruation were evaluated. Results All seven patients (average age: 31 ± 6 years) have experienced amenorrhea (duration range, 48 ± 8 days) before the treatment of HIFU. The average number of pregnancies was four, and the number of deliveries was one. Previous medical history showed six patients had cesarean sections, and five patients have been miscarriages. After HIFU treatment, the fetal heartbeats were stopped in all seven patients based on the diagnosis by doppler ultrasound. The bleeding of gestational tissue decreased significantly. All patients had only mild lower abdominal pain, no fever, intestinal damage, or other complications were reported. The average operation time of operative suction curettage was 21 ± 9 min (range: 9–32 min), and the median bleeding volume was 10 ± 8 mL (range: 2–20 mL). Follow-up observations showed that the menstruations were returned in patients at an average of 38 ± 9 days (range: 30–50 days) after the treatment. The β-hCG decreased from 41773 ± 32242 mIU/mL to 13101 ± 8454 mIU/mL in 29 ± 10 days after surgery. Conclusion Based on these results with small subjects, we concluded that HIFU combined with HGSC might be an effective and safe treatment for patients with cervical pregnancy.

Consanguinity in the Chaouia population (Morocco): prevalence, trends, determinants, fertility, and spontaneous abortions

BackgroundOne of the aspects that helps to understand the genetic structure of a population throughout its biological history is the description of its matrimonial practices. Thus, the objective of this study is to explore consanguinity, one of these practices, to its full extent by identifying the prevalence, determinants, and trends of a consanguineous marriage, as well as its impact on fertility and spontaneous abortions in the Chaouia population, a region located in the western center of Morocco. Therefore, a survey-based cross-sectional study was conducted between January 2019 and January 2020. The sample was collected by province using a stratified random sampling approach, yielding a sample of 788 people. The association between consanguinity and socioeconomic and demographic characteristics, as well as reproductive health and pregnancy outcomes, was described using chi-square and ANOVA analysis. Multivariate logistic regression analysis was used to determine the predictors of a consanguineous marriage.ResultsOur findings revealed a consanguinity rate of 25.38%. The mean inbreeding coefficient was 0.012214. The most common type of union was between first cousins. This practice was strongly associated with an early age at marriage for both genders and with endogamy and immobility of couples, according to their place of birth. Consanguinity was significantly associated with fertility (p < 0.001) and spontaneous abortions (p = 0.029). The average number of pregnancies and spontaneous abortions was higher in consanguineous unions (5.18 ± 0.20/0.47 ± 0.08) compared to non-consanguineous unions (4.33 ± 0.10/0.31 ± 0.03).ConclusionsConsanguinity is a deeply rooted social and cultural tradition in this population, providing individuals with a sense of social-economic stability while assuring their attachment to the group. Despite being highly associated with fertility, this practice has a significant influence on pregnancy outcomes, namely spontaneous abortions. Therefore, further studies are needed to examine the impact of consanguinity on various aspects of reproductive health and its association with numerous genetic abnormalities and diseases.

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy.

ObjectiveThe study retrospectively analyzed the clinical characteristics and prognosis of 17 cases of pregnancy complicated by borderline ovarian tumors to provide help for clinical workers.Materials and MethodsThe clinicopathological data of 17 patients with ovarian borderline tumors during pregnancy at the Shengjing Hospital of China Medical University from January 2015 to June 2021 were collected and analyzed retrospectively. The average age of the patients was 31.82 years (25–45 years), the average number of pregnancies was 2.06 times (1–6 times), and the average number of births was 0.41 times (0–1 time).ResultsAmong the 17 patients, 4 were diagnosed in the first trimester, 2 in the second trimester, and 11 in the third trimester. Most of the first symptoms were cysts, cyst enlargement, or cyst rupture. Among them, 3 cases (1 in the first trimester and 2 in the second trimester) continued pregnancy after a conservative operation, 9 cases underwent cesarean section and a conservative operation simultaneously, and the mother and child had a good outcome. Two cases underwent conservative operations and induced abortion, and 1 case underwent an ectopic pregnancy operation at the same time. The prognosis of the patients was good without recurrence.ConclusionPreoperative diagnosis of borderline ovarian tumors in pregnancy is delayed, and imaging and tumor markers are not specific. The coincidence rate between intraoperative frozen pathology and postoperative paraffin pathology was not high. Borderline tumors are mainly treated by surgery, and the prognosis for mothers and infants is good.

Impact of Immunization Prophylaxis on the Course of Pregnancy in Rh-Negative Women

The purpose of the work was to study the characteristics of the course of pregnancy in women who received Rh immunoprophylaxis. Materials and methods. 64 pregnant women were examined, the average age of whom was 30.55 ± 7.0 (18–43) years. Out of 64 pregnant women, 24 (37.5%) were pre-pregnant, 40 (62.5%) were re-pregnant. The somatic and obstetric anamnesis of all pregnant women included in this study was studied. The average number of pregnancies in 40 repeat-bearing women with Rh (-) blood was 2.34 ± 0.6 (1–5). The obtained results of the study were subjected to statistical processing. At the same time, a computer program "Statgraph" was used, designed for statistical data processing in a parametric and nonparametric way. The work was carried out on the basis of the Educational and Surgical Clinic of the Azerbaijan Medical University. Results and discussion. The study of the course of pregnancy in women with no Rh isosensitization made it possible to establish the presence in the first trimester of a high incidence of anemia (27.3%), vomiting and nausea (21.2%), asymptomatic bacteriuria (17.4%), threatened abortions (14.4%). In the second trimester, there was also a high incidence of anemia (28.6%), asymptomatic bacteriuria (21.4%), threatened abortions (15.7%), exacerbation of chronic pyelonephritis (12.9%), mild preeclampsia (10%). In the third trimester, a high frequency of the menace of uterine rupture along the scar was 22.6%, the threat of preterm birth was 18.5%, and acute respiratory viral infection was 16.9%. It was found that the frequency of abdominal delivery was 73.4%, the frequency of the vaginal birth was 26.6%. A study of the condition of newborns made it possible to establish a satisfactory condition in 70%, a moderate condition in 18.8%, and a serious condition in 6.3% of infants. The severity of the condition was determined by the presence of prematurity in 15.6%, weakness of labor and labor stimulation in 6.3%, and the presence of umbilical cord pathology in 6.3%. None of the newborns had clinical and laboratory manifestations of hemolytic disease of the newborn, which reflects the effectiveness of the prevention of Rh isosensitization, the introduction of anti-D immunoglobulin during pregnancy and after childbirth. Conclusion. The use of anti-D immunoglobulin after previous births and at a gestational age of 27.7 ± 0.09 weeks in present pregnancy eliminates isosensitization in pregnant women with Rh-negative blood. Timely prophylaxis of anti-D immunoglobulin prevents the development of hemolytic disease of the newborn in this group of women. The use of anti-D immunoglobulin is of great importance to reduce perinatal morbidity and mortality in pregnant women with Rh-negative blood

Cytology-based Screening for Anal Intraepithelial Neoplasia in Immunocompetent Brazilian Women with a History of High-Grade Cervical Intraepithelial Neoplasia or Cancer.

To determine the prevalence and possible variables associated with anal intraepithelial neoplasia and anal cancer in immunocompetent women with high-grade cervical intraepithelial neoplasia. A cross-sectional study involving immunocompetent women with a histological diagnosis of high-grade cervical intraepithelial neoplasia and cervical cancer, conducted between January 2016 and September 2020. All women underwent anal cytology and answered a questionnaire on characterization and potential risk factors. Women with altered cytology were submitted to anoscopy and biopsy. A total of 69 women were included in the study. Of these, 7 (10.1%) had abnormal anal cytology results: (high-grade lesion, atypical squamous cells of undetermined significance, and atypical squamous cells, cannot exclude high-grade lesions: 28,5% each; low grade lesion: 14,3%). Of the anoscopies, 3 (42.8%) showed alterations. Of the 2 (28,5% of all abnormal cytology results) biopsies performed, only 1 showed low-grade anal intraepithelial neoplasia. The average number of pregnancies, vaginal deliveries, and abortions was associated with abnormal anal cytology. However, the highest mean regarding the cesarean sections was associated with normal cytology. The prevalence of anal intraepithelial neoplasia was compatible with data from recent studies, especially those conducted in Brazil. Opportunistic screening for anal intraepithelial neoplasia in this high-risk population should be considered. Anal cytology is suitable for this purpose, due to its low cost and feasibility in public health services.

COMPARATIVE CHARACTERISTICS (CASE - CONTROL) OF WOMEN WITH AND WITHOUT ENDOMETRIOID DISEASE

Endometrioid disease today is ranking one of the leading positions in the structure of gynaecological diseases. The prevalence of this endometrioid disease reaches 10% among the female population and up to 70% among women of child-bearing age. Ambiguity in terms of the aetiology, pathogenesis, and predictors of the disease impedes the accurate and quick diagnosis and proper management of this disease.&#x0D; The aim of this study is to analyze and to compare symptomatic and anamnestic data presented by women who have with endometrioid disease and have no it, and to identify and analyze predictors and consequences of endometrioid disease.&#x0D; The study examined 80 women of reproductive age. The main group involved 50 women with endometrioid disease; the control group included 30 women without signs of endometrioid disease. All participants underwent clinical examination and were interviewed about symptoms, family history, menstrual function, past gynaecological, reproductive, infectious (infectious diseases, transferred in childhood), somatic diseases. The information about the presence of psychological and physical overstrain in women of both groups was obtained (subjectively from the words of women) and then assessed.&#x0D; Contributory factors or predictors in the development and progression of endometrioid disease are as follows: an increased number of occupational hazards (22.6% versus 0%, respectively, p = 0.03) among working women with endometrioid disease; regular psychological overstrain, which can result from endometrioid disease on the one hand, and, contribute to its progression, on the other (70% versus 43.3%; p = 0.03); the presence of the 0 blood type (40% versus 16.7%; p = 0.029), the presence of chronic inflammation of the uterine appendages in the past (60% versus 36.6%; p = 0.04); human papilloma virus in past or present medical history (14% versus 0%; p = 0.04).&#x0D; The possible consequences of endometrioid disease include somatic pathology prevailing in 1.3 times. Special attention should be paid to the average number of gastro-intestinal diseases in the women of main and control groups: 1.34 ± 1.3 versus 0.77 ± 1.1, respectively; p = 0.04. The prevalence of diseases of urinary system is as follows: 0.66 ± 0.68 versus 0.33 ± 0.54, respectively; p = 0.04. The menstruations are described as irregular, heaving bleedings often with dark brown discharge before menstruation, pain during menstruation. The study revealed a large percentage of infertility in patients with endometrioid disease (60% versus 33.3%, respectively; p = 0.02), reduced reproductive potential in general (the average number of pregnancies per woman in the control group is 1.9 times higher).&#x0D; It should be noted that 14 (28%) women of the main group have relapse of endometrioid disease in the form of repeated cysts after conservative and / or surgical treatment. Thus, endometrioid disease was detected for the first time in 36 (72%) women of the main group.&#x0D; The information obtained in the study can be helpful for medical practitioners as it deepens knowledge about possible predictor factors, premorbid background and the consequences of endometrioid disease, and, thus, will serve in customized management of such patients.

Investigating the interaction between fertility, pregnancy, and multiple sclerosis.

BACKGROUND:Multiple sclerosis (MS) is a chronic disease of the central nervous system. Most women with MS are diagnosed during their reproductive ages. The aim of this study was to evaluate the interaction between fertility, pregnancy, and MS.MATERIALS AND METHODS:A retrospective descriptive–analytic study was conducted on 110 women suffering from MS with a history of pregnancy (between 2007 and 2017 years) in Isfahan, Iran. Samples were selected in a census model. Women completed a researcher-constructed questionnaire by telephone. The questionnaire consisted of three parts: demographic information, MS and its symptoms and treatment, and reproductive system and the history of pregnancy associated with MS. The data were analyzed by SPSS software version 16 using Chi-square, ANOVA, and t-test.RESULTS:The mean age of women was 32.4 years. In this population, the average number of pregnancies was 1.61, the number of deliveries was 1.35, the number of abortions was 0.24, the history of ectopic pregnancy was 0.01, the number of alive children was 1.36, and the number of dead children was 0.01. The average time of the last MS attack before the pregnancy was 21.36 months. Fatigue (24.5%) was the most common symptom exacerbated during pregnancy. MS symptoms improved in 55.0% of women in the second trimester.CONCLUSIONS:MS had no effect on the pregnancy status, such as the number of abortions, ectopic pregnancy, alive and dead children, and the duration of pregnancy. Symptoms of the disease improved during pregnancy. Therefore, pregnancy has a protective role against MS.

Radiofrequency Treatment of Labia Minora and Majora: A Minimally Invasive Approach to Vulva Restoration.

Summary:Labiaplasty has rapidly increased in popularity over the past 5 years.Traditional labiaplasty is associated with potential complications, such as dehiscence, hematoma, flap necrosis, narrowed introitus, pain, and asymmetry. Minimally invasive techniques such as radiofrequency (RF) have emerged as viable alternatives to traditional labiaplasty through a temperature-controlled bipolar mechanism to heat tissues to target temperatures of 40°C–45°C. This controlled energy delivery leads to an inflammatory cascade initiating neocollagenesis, angiogenesis, and elastogenesis over the coming 3–4 months. A single surgeon series of labia minora and majora treatment by RF (InMode, Lake Forrest, Calif.) was reviewed between April 2018–October 2018. Demographic data were collected as well grade of hypertrophy (pre/posttreatment), number of vaginal deliveries, and reason for treatment. Procedural parameters were recorded, including internal/external temperatures, total energy used, and time of treatment. All adverse events were recorded. Objective and subjective data points were obtained in the form of patient surveys and photographic evaluation by lay persons as well as plastic surgeons objective to the treatment. Ten consecutive patients were treated with bipolar RF (InMode, Lake Forrest, Calif.) between April 2018–October 2018. Mean age was 44 (29–54). Average number of pregnancies was 2 (STD 1.1). Three patients were treated for aesthetic concerns, 3 for functional complaints, and 4 desired improvement in both. Overall graded improvement in labia size/contour was +50% (STD ±15.3). Patient satisfaction scale data demonstrated 9.5/10 (±1.7). All patients (10/10) stated that they would undergo treatment again. In all cases, the surgeon observed tightening of the clitoral hood, introitus, forchett, as well as improved distribution of dark pigmentation of the labia minora. There were no significant complications and no need for additional procedures. Average recovery time was 14 days (STD 2.2). Treatment of labia hyperplasia and laxity with bipolar RF may potentially fill a treatment gap of women seeking aesthetic and functional improvements without surgical labiaplasty. A powered prospective randomized double-blinded study is needed to further elucidate the role of this technology.

PERAN INSEMINASI BUATAN ( IB ) TERHADAP SISTEM PERKAWINAN DIKELOMPOK TANI TERNAK LEMBU KAROMAH KECAMATAN TALUDITI KABUPATEN POHUWATO

This study aims to determine the role of artificial insemination (IB) on the marriage system in the group of caromah cattle farmers in Taluditi Sub-District, Pohuwato Regency. The livestock population of 60 cows consisting of A 32 cages and enclosure B 28 tails. The analysis used was descriptive analysis to get the percentage and average number of pregnancies. Parameters observed include: Service Per Conception (S / C) and Conception Rate (C / R). The results showed that (Service Per Conception) obtained results at enclosure A, the S / C value was 1.7 times, and at enclosure B the S / C value was 1.7 times. The percentage of pregnancy (Conception Rate) is obtained at A cage 79% and the result in cage B is C / R value of 67%. The results obtained are strongly influenced by 4 factors, namely; namely frozen semen, female cattle as IB acceptors, inseminator skills and zooteknis knowledge of farmers. The conclusion of this study is that the success rate of Artificial Insemination in Taluditi District, Pohuwato Regency can be categorized as good.

Significance of Health Related Predictors of Diabetes in Pima Indians Women

This study was carried out to investigate the significance of health-related predictors of diabetes in Pima Indians Women. The study population was the females 21 years and above of Pima Indian heritage patients of diabetes and digestive and kidney diseases. The research question was: what are the health predictions that associated with the presence of diabetes in Pima Indians? The study aimed at testing the significance of health-related predictors of diabetes in Pima Indians women. That was according to World Health Organization criteria (i.e. if the 2-hour post-load plasma glucose was at least 200 mg/dl at any survey examination or if found during routine medical care). A total of 768 women were registered in the database. (268:35%) were having diabetes, while (500:65%) were not. The average number of pregnancies was higher (4.9) in diabetic in comparing to (3.3) in non-diabetic women with a significant difference (P &lt;0.05) between them. Significant (P&lt;0.05) positive correlation (41.7) was found between plasma level and occurrence of diabetes and that patients with a normal range of plasma level were at higher risk of being diabetic. OR = 2.479, [95% CI =1.999, 3.073], P=0.00. The Body Mass Index (BMI) showed a significant association (P&lt;0.05) with the occurrence of diabetes and that even the normal weighted women were at almost 8 times risk of being diabetic in comparison to the overweight, OR = 7.876, [95% CI= 3.557, 17.439]; P=0.00. Significant inverse relation (P&lt;0.05) was seen between the age distribution and diabetic occurrence. Women at age group &lt; 25 years were at higher risk to contract diabetes in comparison to the older age group. OR = 6.616, [CI= 4.145, 10.561], P=0.00. The study concluded that the genetic component is likely to contribute more to the emergence of diabetes in the Pima Indians and their offspring. The study recommended that there should be more preventive input and periodic follow-up especially during pregnancy in this ethnic group to reduce the risk and complications of type II diabetes. Besides, the provision of intervention for weight reduction.

ANALYSIS OF THE OBSTETRIC AND GYNECOLOGICAL ANAMNESIS IN WOMEN WITH A THREATENED ABORTION AFFECTED BY THE ENDOTHELIAL DYSFUNCTION

ANALYSIS OF THE OBSTETRIC AND GYNECOLOGICAL ANAMNESIS IN WOMEN WITH A THREATENED ABORTION AFFECTED BY THE ENDOTHELIAL DYSFUNCTION

267. Sociodemographic profile of pregnant women affected by preeclampsia

Preeclampsia (PE) causes morbidity and mortality in several women in the productive phase, including definitive sequels. Recognizing the socio-demographic profile of pregnant women may justify the allocation of resources to promote an effective care for this population. To describe the socio-demographic profile of pregnant women diagnosed with preeclampsia. Retrospective study of medical records of 98 patients. Place: Hospital Guilherme Álvaro Santos/ Brazil, (from May 2017 to April 2018). Variables analyzed: Previous history of systemic arterial hypertension (SAH) and preeclampsia, first-degree relative with SAH, recreational drug use, cohabitation with the partner, pre-eclampsia, employment status, years of schooling, average number of pregnancies and body mass index (BMI). For all the information in the sample, a description of the data was made through numerical means and descriptive measures of variables with the intention of searching for clues about the behavior of the phenomena studied. The study has ethical approval. We identified that 53.1% had previous SAH; 29% reported a history of preeclampsia; 83% had first-degree relative with SAH; 19% used recreational drugs; 32% lived with partner; 38% were unemployed. How many means: the time of schooling was of 10,23 years; that of pregnancies of 2.27 previous; and the BMI of 31.93 (obesity). These data suggest that it is necessary to create strategies for reproductive planning access for this population because several women were in the third gestation and advised of the risks identified in their own history as relatives with SAH. Avoiding additional complications due to drug use, especially among obese women, hypertensive and with a history of pre-eclampsia and that these guidelines need to be reinforced also by low education. These aspects can be recognized by the anamnesis itself, which can optimize resources and optimize financial resources.

Indexes of natural selection in Kharkiv population

Aim. Reproductive behavior of women has particular importance in the reproduction of the population and depends on cultural characteristics and religious views. Number of birth and medical abortions become artificially regulated; nevertheless selection in human populations does not disappear. Therefore, the aim of this task to study the direction and intensity of indexes of natural selection and the dynamics of the gene pool in the Kharkiv population for two adjacent generations. Methods. The material was collected in 2017. Anonymous questionnaires were conducted for women in postreproductive age. The questionnaire includes questions which reflect a woman's gynecological and obstetrical anamnesis. The number of pregnancies and their outcomes was calculated: medical and spontaneous abortions, ectopic pregnancies, number of stillbirths and live births. Results. In one generation, the total selection index decrease from 0.29 to 0.28, while the differential fertility index is much higher than the differential mortality index. The average number of pregnancies and medical abortions reduced in the younger generation with statistically significant difference. Conclusions. The Kharkov population is characterized by a narrow type of reproduction. The dynamics of Crow's indexes are in line with global trends. From the older generation to the younger the total selection index decreases gradually.Keywords: reproductive characteristics,Kharkov population, Crow's index, selection, generations.

Episiotomy: Epidemiological Aspects, Indications and Prognosis in the Bogodogo Health District

Objectives: To study the epidemiological aspects, indications and short and medium term prognosis of episiotomy in the health district of Bogodogo in Ouagadougou, Burkina Faso. Materials and Method: It was a descriptive prospective study over 4 months from 1 July 2016 to 30 October 2016. It was conducted in 4 health facilities in the health district of Bogodogo in the city of Ouagadougou. The study concerned the patients who gave birth after 28 gestational age (GA) and more, vaginally with episiotomy, in the 4 health facilities and who were reviewed at the appointment of the 9th day and the 3rd month. The data were collected using a questionnaire developed for the purposes of the study, seized with a laptop, then analyzed using the Epi-info software in its 3.5.1 version of the Atlanta C.D.C. Statistical comparisons were made using the Pearson chi-square test, with a significance level of p 0.05. Results: The overall episiotomy rate was 22%. For follow-up, 248 patients were reviewed on the 9th day and 109 patients on the 3rd month. The average age of our patients was 23.1 years. The average number of pregnancies was 1.7 with nulliparous women predominating (60.5% of cases). Excision was associated with episiotomy in 92.3% of cases, with perineal narrowing in 82.5% of patients. The mediolateral episiotomy was the most performed, in 76.6% of patients. Vulvo-perineal stricture was the main indication (75% of cases). The experience during the episiotomy and the evolution following the immediate layer was marked by pain. Dyspareunia was the main difficulty in resuming sexual intercourse. Conclusion: The episiotomy rate in our study was 22%. A program of continuous improvement of the quality of care concerning episiotomy encompassing various actions (audits, training) could reduce the use of episiotomies.

MEDICAL-SOCIAL PORTRAIT OF THE FEMALE PATIENT SUFFERING FROM THE ONCOLOGICAL DISEASE

In the article there are presented results of the analysis of the questionnaire survey of 236 respondents, the executed survey according to specially developed questionnaire has been directed to the study of medico-social features of patients of the gynecologic unit of the Clinical Oncologic Dispensary. The typical patient was established to be typical urban resident aged of 52.6 ± 0.6 years, who has a college education (the highest or specialized secondary), satisfactory living conditions, married and equal smooth relationships in a family. On the one hand, the most part of women (76.3%) were quite active physically during the day (are involved in the work on a personal plot, the private house or played sports), from the other side - 33,8% of respondents had excess weight (25 &lt; IMT &lt; 30). 82.2% of women indicated that they had financial difficulties. The presence of such a harmful habit as smoking was demonstrated by 16.9% of respondents, however, the majority of women (56.7%) do not drink alcohol at all. The obstetric and gynecologic history included menses in the period from 12 to 14 years (79.3%), the most part of the interviewed cases did not show disorders in menses of various character. Average age of the beginning of sex life accounted for 19.5 ± 0.12 years, the average number of pregnancies per 1 woman amounted to 3.4 ± 0.12. Among the leading somatic diseases there were indicated diseases of the circulatory system (27.5%), digestive tract (19,4%), the musculoskeletal system (14%), urinary tract (9.9%) and pathology of respiratory organs (7.5%). The hereditary burdened malignant process took place in 42.6% of respondents, at the same time in most of respondents (51.3%) the disease was registered for the first time.

Prevalence of contraceptives and unmet need for family planning: does geographical location play a role?

Coastal women are the most socio-economically disadvantaged clusters with low literacy and deprived economic and living conditions. The study aims at measuring contraception and unmet need for contraceptive need among married women in the reproductive age group. A cross-sectional study was carried out among222 married women of in a coastal area of Bangladesh. The majority of the respondents (33.8%) were 31 years and above with mean (± SD) age at marriage was 16.2 ± 2.3 years. Most (85.6%) of the study sample were housewives and maximum (84.7%) were literate. About half (50.9%) of them belongs to the single family and about two-thirds (60.4%) monthly family income between 5000 and 10000 Taka. The mean age of women at marriage was 16.2± 2.2 SD, out of which, about two third (63.9%) experienced marriage below 18 years. The average number of pregnancies was 1.9 ± 1.0 SD, out of which, 39.6% experienced two pregnancies. The current contraceptive prevalence rate among married women was 80.2%. The prevalence of unmet need for family planning was 13.5%. The major reason for non-use of contraception among women with unmet need was the husband’s opposition.Asian J. Med. Biol. Res. June 2017, 3(2): 175-181