Significance of Health Related Predictors of Diabetes in Pima Indians Women

Ilham A Bashir,Abdalbasit Adam Mariod,Rasitha Banu,Tahani Babiker Elyas

doi:10.12944/crnfsj.7.2.05

Ilham A Bashir, Abdalbasit Adam Mariod + Show 2 more

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https://doi.org/10.12944/crnfsj.7.2.05

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Abstract

This study was carried out to investigate the significance of health-related predictors of diabetes in Pima Indians Women. The study population was the females 21 years and above of Pima Indian heritage patients of diabetes and digestive and kidney diseases. The research question was: what are the health predictions that associated with the presence of diabetes in Pima Indians? The study aimed at testing the significance of health-related predictors of diabetes in Pima Indians women. That was according to World Health Organization criteria (i.e. if the 2-hour post-load plasma glucose was at least 200 mg/dl at any survey examination or if found during routine medical care). A total of 768 women were registered in the database. (268:35%) were having diabetes, while (500:65%) were not. The average number of pregnancies was higher (4.9) in diabetic in comparing to (3.3) in non-diabetic women with a significant difference (P <0.05) between them. Significant (P<0.05) positive correlation (41.7) was found between plasma level and occurrence of diabetes and that patients with a normal range of plasma level were at higher risk of being diabetic. OR = 2.479, [95% CI =1.999, 3.073], P=0.00. The Body Mass Index (BMI) showed a significant association (P<0.05) with the occurrence of diabetes and that even the normal weighted women were at almost 8 times risk of being diabetic in comparison to the overweight, OR = 7.876, [95% CI= 3.557, 17.439]; P=0.00. Significant inverse relation (P<0.05) was seen between the age distribution and diabetic occurrence. Women at age group < 25 years were at higher risk to contract diabetes in comparison to the older age group. OR = 6.616, [CI= 4.145, 10.561], P=0.00. The study concluded that the genetic component is likely to contribute more to the emergence of diabetes in the Pima Indians and their offspring. The study recommended that there should be more preventive input and periodic follow-up especially during pregnancy in this ethnic group to reduce the risk and complications of type II diabetes. Besides, the provision of intervention for weight reduction.

Highlights

Diabetes is a group of metabolic diseases that have high levels of sugar in the blood over a long period of time, so it is known as a chronic illness.1 Glucose enters the body through the intestines treated by the patient, and here comes the role of insulin which is a hormone that helps glucose to enter the cells to give energy
In 1993, the highest prevalence of type 2 diabetes (NIDDM) in the world was found in Pima Indians living in Arizona
Subsequent studies showed that Pima Indians had high insulin and insulin resistance comparisond to other ethnic groups and that people with diabetes, even those at an early age did not appear antibodies to anti-toxin cells

Summary

Introduction

Diabetes is a group of metabolic diseases that have high levels of sugar in the blood over a long period of time, so it is known as a chronic illness. Glucose enters the body through the intestines treated by the patient, and here comes the role of insulin which is a hormone that helps glucose to enter the cells to give energy. There is a rise in glucose in pre-diabetes This means that blood sugar is above normal but not too high to name diabetes. Gestational diabetes causes high blood sugar that can affect the pregnancy and the baby's health.. Results indicate that the highest prevalence of diabetes is found in high rates in Indian Pima, and this is shown by comparing natural groups with hyperglycemic on the basis of the relative distribution of glucose levels after pregnancy for two hours.. In 1993, the highest prevalence of type 2 diabetes (NIDDM) in the world was found in Pima Indians living in Arizona.. Subsequent studies showed that Pima Indians had high insulin and insulin resistance comparisond to other ethnic groups and that people with diabetes, even those at an early age did not appear antibodies to anti-toxin cells.

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