Average Energy Resolution Research Articles

Physical and imaging performance of SIAT aPET under different energy windows and timing windows.

The performance of small animal PET scanners depends on the energy window (EW) and timing window (TW). In National Electrical Manufacturers Association (NEMA) Standards Publication NU 4-2008, detailed procedures of the performance measurements are defined, but the EW and TW are not specified. In this work, the effects of EW and TW on the physical and imaging performance of Shenzhen Institute of Advanced Technology small animal PET (SIAT aPET) will be evaluated. First, the flood histogram, energy resolution, and timing resolution were measured for a detector of SIAT aPET. Second, the spatial resolutions were measured with different EWs. Third, the sensitivities, the scatter fractions (SFs), and noise equivalent count rates (NECRs) of a mouse-sized phantom and a rat-sized phantom, the recovery coefficients (RCs) of rods of different sizes, and the percentage standard deviation (%STD) of the NEMA image quality phantom were measured for different EWs and TWs. Last, images of a hot rod phantom, a mouse heart, and a rat brain were acquired from the scanner with different EWs. The SIAT aPET detectors provided good flood histograms such that all but the corner crystals can be resolved even with lower energies of 250-350keV, an average energy resolution of 21.1 ± 1.9%, and an average timing resolution of 2.63 ± 0.69ns. The average spatial resolutions obtained with EWs of 250-350keV and 450-550keV are 0.68mm and 0.75mm. For EWs of 250-750keV, 350-750keV, and 450-750keV with a fixed TW of 12ns, the sensitivities at the center of field of view (FOV) are 16.0%, 11.9%, and 8.2%, the peak NECRs of a mouse-sized phantom are 355.6 kcps, 324.4 kcps, and 249.4 kcps, and the peak NECRs of a rat-sized phantom are 148.5 kcps, 144.3 kcps, and 117.7 kcps, respectively. For the TWs of 4ns, 8ns,12ns, and 20ns with a fixed EW of 350-750keV, the sensitivities at the center of FOV are 9.6%, 11.4%, 11.9%, and 12.2%, the peak NECRs of a mouse-sized phantom are 260.1 kcps, 311.5 kcps, 324.4 kcps and 324.9 kcps, and the peak NECRs of a rat-sized phantom are 110.5 kcps, 137.3 kcps, 144.3 kcps, and 142.6 kcps, respectively. Narrowing the EW and TW improves the RCs of rods of all sizes, and the %STD of images obtained with different EWs and TWs are similar. Rods with diameter down to 0.8mm can be visually resolved from images of the hot rod phantom obtained with different EWs. Images of mouse heart with high spatial resolution and rat brain with detail brain structure were obtained with different EWs. Images of both phantom and in vivo animals obtained with different EWs only showed subtle difference. The performance of SIAT aPET under different EWs and TWs was compared. The EW and TW affect the sensitivity, SF, and NECR but not the spatial resolution and animal images of SIAT aPET, which imply that careful optimization of the EW and TW is not required.

A time-based single transmission-line readout with position multiplexing.

We developed a time-based single-transmission-line readout method for time-of-flight positron emission tomography (PET) detectors. The 2D position of a silicon photomultiplier (SiPM) array was encoded in the upper and lower widths of a specially prepared L-shaped tag pulse followed by the original scintillation signal. A PET detector setup was configured using a 4 × 4 array of LSO crystals optically coupled one-to-one to a 4 × 4 SiPM array. Two pulse width modulator circuits were employed per SiPM anode signal channel and a total of 32 width-modulated digital pulses were summed and merged with a delayed common-cathode signal. The final output was analyzed using timestamps crossing two-level threshold voltages. All 16 crystals were clearly separated on a positioning map. The average energy and coincidence time resolutions were 15.0 ± 1.1% and 288.7 ± 29.3ps after proper correction process, respectively. A 3D position decoding capability was also shown by the remarkable discrimination performance in a phoswich PET detector setup (LSO and LGSO), resulting from well-preserved scintillation signals. The proposed method enables a time-based single-channel readout with 3D gamma ray interaction position decoding capability without compromising on detector performance. This method provides gamma ray energy and arrival time information as well as 2D and depthwise interaction positions of the phoswich detectors through one channel readout. Thus, channels can be reduced by at least 4-5 times compared to typically employed charge-sharing-based position multiplexing method; this significantly reduces the burden of data acquisition on the PET system.

GERDA and LEGEND: Probing the Neutrino Nature and Mass at 100 meV and beyond

The Gerda (GERmanium Detector Array) project, located at Laboratori Nazionali del Gran Sasso (LNGS), was started in 2005, a few years after the claim of evidence for the neutrinoless double beta decay (0νββ) of 76Ge to the ground state of 76Se: it is an ultra-rare process whose detection would directly establish the Majorana nature of the neutrino and provide a measurement of its mass and mass hierarchy. The aim of Gerda was to confirm or disprove the claim by an increased sensitivity experiment. After establishing the new technology of Ge detectors operated bare in liquid Argon and since 2011, Gerda efficiently collected data searching for 0νββ of 76Ge, first deploying the 76Ge-enriched detectors from two former experiments and later new detectors with enhanced signal-to-background rejection, produced from freshly 76Ge-enriched material. Since then, the Gerda setup has been upgraded twice, first in 2013–2015 and later in 2018. The period before 2013 is Phase I and that after 2015 is Phase II. Both the Gerda setup and the analysis tools evolved along the project lifetime, allowing to achieve the remarkable average energy resolution of ∼3.6 and ∼2.6 keV for Coaxial Germanium (Coax) detectors and for Broad Energy Germanium (BEGe), respectively, and the background index of 5.2−1.3+1.6 · 10−4 cts/(keV·kg·yr) in a 230 keV net range centered at Qββ. No evidence of the 0νββ decay at Qββ = 2039.1 keV has been found, hence the limit of 1.8·1026 yr on the half-life (T1/20ν) at 90% C.L. was set with the exposure of 127.2 kg·yr. The corresponding limit range for the effective Majorana neutrino mass mee has been set to 79–180 meV. The Gerda performances in terms of background index, energy resolution and exposure are the best achieved so far by 76Ge double beta decay experiments. In Phase II, Gerda succeeded in operating in a background free regime and set a world record. In 2017, the Legend Collaboration was born from the merging of the Gerda and Majorana Collaborations and resources with the aim to further improve the Gerda sensitivity. First, the Legend200 project, with a mass of up to 200 kg of 76Ge-enriched detectors, aims to further improve the background index down to <0.6 · 10−3 cts/(keV·kg·yr) to explore the Inverted Hierarchy region of the neutrino mass ordering, then the Legend1000 (1 ton of 76Ge-enriched) will probe the Normal Hierarchy. In this paper, we describe the Gerda experiment, its evolution, the data analysis flow, a selection of its results and technological achievements, and finally the design, features and challenges of Legend, the Gerda prosecutor.

ARDESIA-16: a 16-channel SDD-based spectrometer for energy dispersive X-ray fluorescence spectroscopy

We present ARDESIA-16, an X-ray spectrometer based on a monolithic 16-element Silicon Drift Detector (SDD) matrix specifically designed for synchrotron applications. In this work, we describe the main design guidelines which we followed concerning the signal throughput, the energy efficiency, the energy resolution and the overall solid angle covered by detector elements. The characterization of the spectrometer has been made both with radioactive sources in a laboratory environment and with synchrotron light at the P06 beamline (DESY, Hamburg). Experimental results showed an average energy resolution at the optimum peaking time equal to 125 eV (FWHM at Mn Kα), a maximum achieved Output Count Rate (OCR) equal to 17 Mcps, an increase of the energy efficiency above 10 keV thanks to the 1 mm-thick SDD and an overall solid angle equal to 0.4 sr. Finally, we report the first X-ray fluorescence microscopy (XFM) images acquired with an ARDESIA spectrometer.

Performance evaluation of a staggered three-layer DOI PET detector using a 1 mm LYSO pitch with PETsys TOFPET2 ASIC: comparison of HAMAMATSU and KETEK SiPMs

In this study, we propose a staggered three-layer depth-of-interaction (DOI) detector with a 1 mm crystal pitch and 19.8 mm total crystal thickness for a high-resolution and high-sensitivity small animal in-beam PET scanner. A three-layered stacked LYSO scintillation array (0.9 × 0.9 × 6.6 mm3 crystals, 23 × 22 mm2 surface area) read out by a SiPM array (8 × 8 channels, 3 × 3 mm2 active area/channel and 50 μm microcell size) with data acquisition, signal processing and digitization performed using the PETsys Electronics Evaluations kit (based on the TOFPET v2c ASIC) builds a DOI LYSO detector block. The performance of the DOI detector was evaluated in terms of crystal resolvability, energy resolution, and coincidence resolving time (CRT). A comparative performance evaluation of the staggered three-layer LYSO block was conducted with two different SiPM arrays from KETEK and HAMAMATSU. 100% (KETEK) and 99.8% (HAMAMATSU) of the crystals were identified, by using a flood irradiation the front- and back-side. The average energy resolutions for the 1st, 2nd, and 3rd layers were 16.5 (±2.3)%, 20.9(±4.0)%, and 32.7 (±21.0)% (KETEK) and 19.3 (±3.5)%, 21.2 (±4.1)%, and 26.6 (±10.3)% (HAMAMATSU) for the used SiPM arrays. The measured CRTs (FWHM) for the 1st, 2nd, and 3rd layers were 532 (±111) ps, 463 (±108) ps, and 447 (±111) ps (KETEK) and 402 (±46) ps, 392 (±54) ps, and 408 (±196) ps (HAMAMATSU). In conclusion, the performance of the staggered three-layer DOI detector with 1 mm LYSO pitch and 19.8 mm total crystal thickness was fully characterized. The feasibility of a highly performing readout of a high resolution DOI PET detector via SiPM arrays from KETEK and HAMAMATSU employing the PETsys TOFPET v2c ASIC could be demonstrated.

Serial line multiplexing method based on bipolar pulse for PET

Although the individual channel readout method can improve the performance of PET detectors with pixelated photo-sensors, such as silicon photomultiplier (SiPM), this method leads to a significant increase in the number of readout channels. In this study, we proposed a novel multiplexing method that could effectively reduce the number of readout channels to reduce system complexity and development cost. The proposed multiplexing circuit was designed to generate bipolar pulses with different zero-crossing points by adjusting the time constant of the high-pass filter connected to each channel of a pixelated photo-sensor. The channel position of the detected gamma-ray was identified by estimating the width between the rising edge and the zero-crossing point of the bipolar pulse. In order to evaluate the performance of the proposed multiplexing circuit, four detector blocks, each consisting of a 4 × 4 array of 3 mm × 3 mm × 20 mm LYSO and a 4 × 4 SiPM array, were constructed. The average energy resolution was 13.2 ± 1.1% for all 64 crystal pixels and each pixel position was accurately identified. A coincidence timing resolution was 580 ± 12 ps. The experimental results indicated that the novel multiplexing method proposed in this study is able to effectively reduce the number of readout channels while maintaining accurate position identification with good energy and timing performance. In addition, it could be useful for the development of PET systems consisting of a large number of pixelated detectors.

High-resolution for IAXO: MMC-based X-ray detectors

Axion helioscopes like the planned International Axion Observatory (IAXO) search for evidence of axions and axion-like particles (ALPs) from the Sun. A strong magnetic field is used to convert ALPs into photons via the generic ALP-photon coupling. To observe the resulting photons, X-ray detectors with low background and high efficiency are necessary. In addition, good energy resolution and low energy threshold would allow for investigating the ALP properties by studying the X-ray spectrum after its discovery. We propose to use low temperature metallic magnetic calorimeters (MMCs). Here we present the first detector system based on MMCs developed for IAXO and discuss the results of the characterization. The detector consists of a two-dimensional 64-pixel array covering an active area of 16mm2 with a fill factor of 93%. We achieve an average energy resolution of 6.1 eV FWHM allowing for energy thresholds below 100 eV. This detector is the first step towards a larger 1 cm2 array matching the IAXO X-ray optics. We determine the background rate for an unshielded detector system in the energy range between 1 keV and 10 keV to be 3.2(1) × 10-4 keV-1 cm-2 s-1 from events acquired over 30 days. In the future, active and passive shields will significantly reduce the background induced by cosmic muons and natural radioactivity. Our results demonstrate that MMCs are a promising technology for helioscopes to discover and study ALPs.

Optimization of the surface area of laser-induced layers for PET detectors with depth-of-interaction

Detectors with depth-of-interaction (DOI) information are utilized in positron emission tomography (PET) scanners to improve the sensitivity of radiation detection and the uniformity of spatial resolution. We recently developed a series of dual-ended detectors using crystal bars segmented by applying the subsurface laser engraving (SSLE) technique to 7, 13 and 20 DOI segments. It is crucial to achieve the submillimeter level spatial resolution for our detector as the narrow crystal bars are highly fragile after applying the SSLE technique. In this work, we focused on optimizing the surface area of the SSLE-induced layer to the narrow crystal bars in order to resolve the issue of fragility while maintaining sufficient crystal segment separation. The SSLE layers were induced to the middle of the cross section of the five crystal bars with dimensions of 1.5 ×1.5× 20 mm3 with a distance of 0.1, 0.2, 0.3, 0.4 or 0.5 mm from the two opposite lateral edges of each crystal bar. All crystals were segmented into four DOI segments and the performances of the five sets of dual-ended DOI detectors consisting of one crystal bar were evaluated from the viewpoints of optimum crystal segment identification and energy resolution while mitigating the fragility issue. The 3D position maps of the detectors were obtained by the Anger-type calculation, and the crystal identification performance was evaluated. Clear separation of the segments with a distance-to-width ratio (DWR) larger than 7 was obtained for the detectors in which the distances of the SSLE-induced layer from the two opposite lateral edges of the crystal were 0.1, 0.2 and 0.3 mm. The DWR for the other two detectors was less than 4.4. Average energy resolutions of 11.8 ± 0.2%, 10.6 ± 0.2% and 8.8 ± 0.2% were obtained for the detectors in which the SSLE layers were induced with 0.1, 0.3 and 0.5 mm distances from the two opposite lateral edges of the crystal, respectively. There was a compromise between energy resolution and crystal segment identification. The optimum surface area of the SSLE-induced layer was accepted as a trade-off between crystal segment identification and fragility. The crystal segmented by the SSLE-induced layer at the middle of the cross section with a distance of 0.3 mm from the two opposite lateral edges was considered to be a good candidate with acceptable performance and fragility.

A high resolution and high detection efficiency depth-encoding detector for brain positron emission tomography based on a 0.75 mm pitch scintillator array

The quantitative accuracy and precision of brain positron emission tomography (PET) studies can be considerably improved using dedicated brain PET scanners with a uniform high resolution and a high sensitivity across the brain volume. One approach to building such a system is to construct the PET scanner using depth-of-interaction (DOI) encoding detectors with finely segmented and thick crystal arrays. In this paper, the performance of a DOI PET detector based on two 16 × 16 arrays of 2 × 2 mm^2 SiPMs coupled to both ends of a 44 × 44 array of 0.69 × 0.69 × 30 mm3 polished LYSO crystals was evaluated at different temperatures (-9∘C, 0∘C, 10∘C, and 20∘C) for brain PET applications. The pitch size of the LYSO array is 0.75 mm. The flood histograms show that all the crystal elements in the LYSO array can be resolved except some edge crystals, due to the limited light sharing. The average energy resolution, average DOI resolution, and average timing resolution across crystal elements are 21.1 ± 3.0%, 3.47 ± 0.17 mm, and 1.38 ± 0.09 ns, respectively, which were obtained at a bias voltage of 56.5 V and a temperature of 0∘C.

Toroidal soft x-ray array on the EXL-50 spherical tokamak

A toroidal soft x-ray array system for spectrum and intensity measurements on the EXL-50 spherical tokamak is described. Silicon drift detectors and digital multichannel analyzers are adopted for all 21 channels of the array, and an average energy resolution of 147eV at 5.89 keV has been achieved at count rates over 500 kcps. In total, 20 channels of the array are symmetrically observed in both co- and counter-current directions on the EXL-50 mid-plane with a spatial resolution of around 10cm, and the remaining one serves as a background reference channel. Tungsten emissions from tungsten coating of the limiters on the central post are observed. The influence of hard x rays on measured soft x-ray spectra and system operation is discussed.

Development of neutron time-of-flight measurement system for 1.7-MV tandem proton accelerator with lithium target

In this study, we developed a neutron time-of-flight (nTOF) measurement system for a 1.7-MV tandem proton accelerator with a target covered with 300-nm-thick lithium (Li) layer. With implementation of beam chopping module after its ion source, the accelerator is configured to operate in pulsed-beam mode with a pulse width <50 ns at 20-kHz repetition rate. This enables the gamma flash-type nTOF measurement system to identify the neutron generated with 3-MeV proton beam energy. The nTOF system consists of a 3″ cylindrical NaI(Tl) and four stilbene scintillation detectors. The NaI(Tl) scintillator is placed 50 cm from the Li target to measure the time of beam irradiation on the target, and the stilbene detectors are placed 2 and 2.4 m away to measure nTOF at each location. The nTOF system successfully measured the generated neutron energy at irradiated proton energies of 2.6 and 3.0 MeV with an average energy resolution of 15%.

Characterization of cubic Li_{2}^{100}MoO_4 crystals for the CUPID experiment

The CUPID Collaboration is designing a tonne-scale, background-free detector to search for double beta decay with sufficient sensitivity to fully explore the parameter space corresponding to the inverted neutrino mass hierarchy scenario. One of the CUPID demonstrators, CUPID-Mo, has proved the potential of enriched Li_{2}^{100}MoO_4 crystals as suitable detectors for neutrinoless double beta decay search. In this work, we characterised cubic crystals that, compared to the cylindrical crystals used by CUPID-Mo, are more appealing for the construction of tightly packed arrays. We measured an average energy resolution of (6.7pm 0.6) keV FWHM in the region of interest, approaching the CUPID target of 5 keV FWHM. We assessed the identification of alpha particles with and without a reflecting foil that enhances the scintillation light collection efficiency, proving that the baseline design of CUPID already ensures a complete suppression of this alpha -induced background contribution. We also used the collected data to validate a Monte Carlo simulation modelling the light collection efficiency, which will enable further optimisations of the detector.

A prototype of SiPM-based scintillator Compton camera with capacitive multiplexing readout

Compton camera is capable of visualizing the distribution of radioactivity based on the Compton scattering kinematics, and can be applied in nuclear accident emergency response, radioactivity decontamination, homeland security and etc. A prototype of Compton camera has been constructed consisting of two 4×4 SiPM-Ce: GAGG scintillator arrays. The signals of a SiPM array were converted into 4 position-weighted outputs with capacitive network circuit and collected by a CAEN digitizer. Two-dimensional flood images and energy responses of two detector modules were obtained. The average energy resolution of single elements of the two detector modules was 6.6% FWHM at 662 keV. Imaging performance of the prototype camera was evaluated with a 137Cs point source and a 22Na point source. Efficiency of the prototype for the 137Cs point source located right in front was measured to be 0.09%. The angular resolution of a 137Cs point source placed right in front of the camera was 7.2° FWHM. Isotopic images of the two gamma-ray sources were obtained with spatial resolutions of 8.2° FWHM for 137Cs and 8.8° FWHM for 22Na.

Performance comparison of dual-ended readout depth-encoding PET detectors based on BGO and LYSO crystals

The performance of dual-ended readout depth-encoding positron emission tomography (PET) detectors based on bismuth germanate (BGO) coupled to silicon photomultipliers (SiPM) arrays was measured for the first time and compared to lutetium-yttrium oxyorthosilicate (LYSO)-based detectors using the same readout. The BGO and LYSO crystal arrays all had a crystal pitch of 2.2 mm and were coupled to 8 × 8 SiPM arrays with a matching pitch of 2.2 mm, using a one-to-one coupling configuration. Three types of crystals with Toray reflector were used: polished LYSO, polished BGO, and unpolished BGO, and for two different crystal thicknesses of 20 mm and 30 mm. All the crystal elements in the BGO arrays were clearly resolved in the flood histogram. Better flood histograms were obtained using the LYSO arrays for a selected crystal thickness, and better flood histograms were obtained using the 20 mm thick crystal arrays for a selected crystal type. The average crystal level energy resolution and timing resolution for 20 mm polished LYSO, polished BGO and unpolished BGO crystals at their optimal SiPM bias voltage were 18.6 ± 1.3% and 1.19 ± 0.20 ns, 17.8 ± 0.8% and 4.43 ± 0.47 ns, and 18.0 ± 1.0% and 4.68 ± 1.0 ns, respectively. Depth-of-interaction (DOI) resolution of the 20 mm polished LYSO array was 2.31 ± 0.17 mm and for the 20 mm unpolished BGO array was 3.53 ± 0.25 mm. However, polished BGO arrays with Toray reflector did not provide DOI information. Our key conclusion is that dual-ended readout depth-encoding 20 mm thick unpolished BGO detectors are good candidates for low-activity PET systems with small field-of-view and low timing performance requirements, such as preclinical or compact organ-dedicated PET systems, with the advantage over LYSO of having no background radiation and significantly lower cost.

Design and Evaluation of LYSO/SiPM LIGHTENING PET Detector with DTI Sampling Method.

Positron emission tomography (PET) has a wide range of applications in the treatment and prevention of major diseases owing to its high sensitivity and excellent resolution. However, there is still much room for optimization in the readout circuit and fast pulse sampling to further improve the performance of the PET scanner. In this work, a LIGHTENING PET detector using a 13 × 13 lutetium-yttrium oxyorthosilicate (LYSO) crystal array read out by a 6 × 6 silicon photomultiplier (SiPM) array was developed. A novel sampling method, referred to as the dual time interval (DTI) method, is therefore proposed to realize digital acquisition of fast scintillation pulse. A semi-cut light guide was designed, which greatly improves the resolution of the edge region of the crystal array. The obtained flood histogram shown that all the 13 × 13 crystal pixels can be clearly discriminated. The optimum operating conditions for the detector were obtained by comparing the flood histogram quality under different experimental conditions. An average energy resolution (FWHM) of 14.3% and coincidence timing resolution (FWHM) of 972 ps were measured. The experimental results demonstrated that the LIGHTENING PET detector achieves extremely high resolution which is suitable for the development of a high performance time-of-flight PET scanner.

Development and initial characterization of a high-resolution PET detector module with DOI

Organ-dedicated PET scanners are becoming more prevalent because of their advantages in higher sensitivity, improved image quality, and lower cost. Detectors utilized in these scanners have finer pixel size with depth of interaction (DOI) capability. This work presents a LYSO(Ce) detector module with DOI capability which has the potential to be scaled up to a high-resolution small animal or organ-dedicated PET system. For DOI capability, a submodule with one LYSO block detector utilizing PETsys TOFPET2 application-specific integrated circuit (ASIC) was previously developed in our lab. We scaled up the submodule and optimized the configuration to allow for a compact housing of the dual-readout boards in one side of the blocks by designing a high-speed dual-readout cable to maintain the original pin-to-pin relationship between the Samtec connectors. The module size is 53.8 × 57.8 mm2. Each module has 2 × 2 LYSO blocks, each LYSO block consists of 4 × 4 LYSO units, and each LYSO unit contains a 6 × 6 array of 1 × 1 × 20 mm3 LYSO crystals. The four lateral surfaces of LYSO crystal were mechanically ground to W14, and the two end surfaces were polished. Two ends of the LYSO crystal are optically connected to SiPM for DOI measurement. Eight LYSO blocks performance including energy, timing, and DOI resolution is characterized with a single LYSO slab. The in-panel and orthogonal-panel spatial resolution of the two modules with 107.4 mm distance between each other are measured at 9 positions within the field of view (FOV) with a 22Na source. Results show that the average energy, timing, and DOI resolution of all LYSO blocks are 16.13% ± 1.01% at 511 keV, 658.03 ± 15.18 ps, and 2.62 ± 0.06 mm, respectively. The energy and timing resolution of two modules are 16.35% and 0.86 ns, respectively. The in-panel and orthogonal-panel spatial resolution of the two modules at the FOV center are 1.9 and 4.4 mm respectively.

Development of Gamma-Ray Detector Arrays Consisting of Diced Eu-Doped SrI2 Scintillator Arrays and TSV-MPPC Arrays

This article presents the development of diced SrI2:Eu arrays and their scintillation properties when coupled with a multipixel photon counter (MPPC) array. Using a dicing technique specific to halide scintillators, a high-energy resolution scintillator array is developed that is cost-effective and widely applicable. The developed SrI2:Eu arrays are of $3 \times 3 \times 3$ mm3/pixel $4 \times 4$ matrix (TYPE1) and $1 \times 1 \times 1$ mm3/pixel $9 \times 9$ matrix (TYPE2) structures. We fabricated test gamma-ray detector modules consisting of the TYPE1 and TYPE2 arrays coupled with an MPPC array. The mean peak to valleys ratio is 85.3 ± 14.9 for the TYPE1 array and 38.5 ± 16.6 for the TYPE2 array detector. The average energy resolutions obtained for the TYPE1 and TYPE2 gamma-ray detectors were 5.4 ± 0.4% full-width at half-maximum (FWHM) and 5.2 ± 0.6% FWHM, respectively, for 662-keV gamma-rays. The variation in the signal pulse height of the TYPE1 and TYPE2 detectors was only 10.6% and 10.4% in FWHM, respectively. These results demonstrated that the dicing technique proposed in this article could be applied to hygroscopic halide scintillators.

A position sensitive scintillation detector using a side-by-side GAGG-F/GAGG-T phoswich block

Position sensitive detectors are the key component of gamma-ray imaging systems such as coded-aperture cameras and emission computed tomography systems. Improving the intrinsic spatial resolution of detectors is critical to system performances. Recent advance of the GAGG scintillator production allows variable decay time with different Al/Ga ratios. In this paper, we developed a novel position sensitive scintillation detector using a side-by-side fast\ obreakdash-GAGG/typical-GAGG (GAGG-F/GAGG-T) phoswich array, which consisting of 12×12 phoswich unit pairs assembled by the GAGG-F scintillator (decay time constant ∼ 50 ns) and the GAGG-T scintillator (decay time constant ∼ 90 ns) in a pixel size of 1.35×2.7×4 mm3 and coupled to a 8×8 SiPM (MicroFJ\ obreakdash-30035\ obreakdash-TSV) array. An experiment was conducted using the irradiation of a 57Co source (122 keV) . Experimental results demonstrate that events from the GAGG\ obreakdash-F and GAGG-T scintillators can be discriminated with only 7% mis-assignment probability. The 12×12 of GAGG\ obreakdash-F and GAGG-T scintillator arrays are both distinguishable in separated flood maps. The average energy resolutions of GAGG\ obreakdash-F and GAGG-T scintillators at 122 keV are 27.58% and 23.51% respectively. The side-by-side GAGG-F/GAGG-T detector has the advantage of improved intrinsic spatial resolution, no intrinsic background radiation and uniform detection efficiency.

Performance evaluation of HiPET, a high sensitivity and high resolution preclinical PET tomograph

HiPET is a recently developed prototype preclinical PET scanner dedicated to high sensitivity and high resolution molecular imaging. The HiPET system employs a phoswich depth of interaction (DOI) detector design, which also allows identification of the large majority of the cross layer crystal scatter (CLCS) events. This work evaluates its performance characteristics following the National Electrical Manufacturers Association (NEMA) NU4-2008 protocol.The HiPET consists of twenty flat panel type detectors arranged in two rings. The inner diameter is 160 mm and the axial field of view (FOV) is 104 mm. Each detector is comprised of two layers of phoswich scintillator crystal arrays, a tapered, pixelated glass lightguide and a multi anode photomultiplier tube (MAPMT). The front (gamma ray entrance) layer is a 48 × 48 pixelated cerium doped lutetium yttrium orthosilicate (LYSO) scintillator array with individual crystals measuring 1.01 × 1.01 × 6.1 mm. The back (towards the PMT) layer is a 32 × 32 pixelated bismuth germanate (BGO) scintillator array with individual crystals measuring 1.55 × 1.55 × 8.9 mm.For energy windows of 250–650 keV and 350–650 keV, the peak absolute sensitivity at the center of the FOV was 13.5% and 10.4% including CLCS events, and 11.8% and 8.9% excluding CLCS events, respectively. The average detector energy resolution derived by averaging the individual crystal spectra was 11.7% ± 1.4% for LYSO and 17.0% ± 1.4% for BGO. The 3D ordered-subsets expectation maximization (OSEM) reconstructed image of a point source in air, ranged from 0.73 mm to 1.19 mm, with an average value of 0.93 ± 0.09 mm at all measured locations. The peak noise equivalent count rate (NECR) and scatter fraction were 179 kcps at 12.4 MBq and 6.9% for the mouse-sized phantom, and 63 kcps at 11.3 MBq and 18.3% for the rat-sized phantom. For the NEMA image quality phantom, the uniformity was 5.8%, and the spillover ratios measured in the water- and air-filled cold region chambers were 0.047 and 0.044, respectively. The recovery coefficients (RC) ranged from 0.31 to 0.92.These results and in vivo evaluation demonstrate that the HiPET can achieve high quality molecular imaging for biomedical applications.

Progress in the Development of Frequency-Domain Multiplexing for the X-ray Integral Field Unit on Board the Athena Mission

Frequency domain multiplexing (FDM) is the baseline readout system for the X-ray Integral Field Unit (X-IFU) on board the Athena mission. Under the FDM scheme, TESs are coupled to a passive LC filter and biased with alternating current (AC bias) at MHz frequencies. Using high-quality factor LC filters and room temperature electronics developed at SRON and low-noise two-stage SQUID amplifiers provided by VTT, we have recently demonstrated good performance with the FDM readout of Mo/Au TES calorimeters with Au/Bi absorbers. We have achieved a performance requested for the demonstration model (DM) with the single pixel AC bias ($\Delta E=$1.8 eV) and 9 pixel multiplexing ($\Delta E=$2.6 eV) modes. We have also demonstrated 14-pixel multiplexing with an average energy resolution of 3.3 eV, which is limited by non-fundamental issues related to FDM readout in our lab setup.