This paper presents the experimental results of condensation heat transfer coefficients of hydrocarbon (HC) refrigerants R-290 and R-600a, hydrochlorofluorocarbon (HCFC) refrigerant R-22, and hydrofluorocarbon (HFC) refrigerant R-134a in a horizontal double-pipe heat exchanger having pipe inner diameters of 10.07, 7.73, 6.54, and 5.80 mm. The condensation process experiments were conducted at mass flux of 35.5–210.4 kg/m2 s and condensation temperature of 40°C. The main results were summarized as follows: The average condensation heat transfer coefficients of R-290 and R-600a were higher than those of R-22 and R-134a. The pressure drops of the four refrigerants were in the order of R-600a > R-290 > R-134a > R-22. The pressure drops of R-600a, R-290, R-134a, and R-22 were approximately 6–15, 9.8–12.5, 4.3–6.7, and 2.1–4.6% higher, respectively, in the 10.7 mm diameter tubes compared to the 5.80 mm diameter tubes. Comparing the condensation heat transfer coefficients of our experimental results with those of other correlations, our experimental data in all the test tubes coincided best with that of Haraguchi et al.