Background: Complete Basic Immunization (CBI) is essential to prevent vaccine-preventable diseases (VPDs). However, the coverage of complete basic immunization in Banggai Laut Regency remains low at 67.9%, compared to the national target of 90%. Several factors, including maternal knowledge, attitudes, accessibility to healthcare facilities, healthcare workers' roles, family support, and maternal occupation, are believed to influence maternal behavior in immunization provision. This study aimed to analyze factors affecting maternal behavior in achieving complete basic immunization for toddlers aged 12–23 months in Banggai Laut Regency. Methodology: This cross-sectional analytical survey involved 321 mothers selected through cluster random sampling. Data were collected using structured questionnaires and analyzed using Chi-Square tests and logistic regression. Results: Significant associations were found between complete basic immunization and good knowledge (p<0.000; OR=3.2), positive attitudes (p<0.000; OR=2.8), availability of healthcare facilities (p<0.000; OR=3.4), proximity to healthcare services (p<0.000; OR=3.7), supportive roles of healthcare workers (p<0.000; OR=2.9), and strong spousal support (p<0.000; OR=2.5). Maternal occupation showed no significant effect (p=0.379). Conclusions: Knowledge, attitude, availability of healthcare facilities, distance to healthcare facilities, spousal support, and the role of healthcare workers are key factors in improving the coverage of complete basic immunization. Interventions targeting these factors are essential to achieving national immunization targets in Banggai Laut Regency.
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