In the ever-evolving field of materials science, the quest for innovative design solutions continues. One such area of research is the optimization of auxetic performance in meta-hybrid structures. This study delves into the application of machine learning analysis to enhance the properties of a specific meta-hybrid structure combining re-entrant and meta-trichiral designs. The polymeric meta-hybrid structure is subjected to finite element (FE) analysis to determine its Poisson's ratio. Various machine learning methods, such as linear, quadratic, and non-linear approaches, are employed to accurate forecast the Poisson's ratio of the polymeric meta-hybrid structure. Although both linear and quadratic machine learning algorithms have shown some success in predicting Poisson's ratios, they cannot be considered outstanding. As a result, a non-linear machine learning algorithm has been developed to enhance the accuracy of Poisson's ratio prediction. The results indicate that non-linear machine learning techniques out performs both linear and quadratic methods when it came to predicting Poisson's ratio. Specifically, the non-linear model achieved an impressive R-sq value of 93.68%, demonstrating its exceptional accuracy and overall excellence in fitting the data. The optimum conditions for the meta-hybrid structure are determined to be a thickness of 4.35 mm, a temperature of 15 °C, and a strain rate of 1%. Under these specific parameters, the Poisson's ratio of the meta-hybrid structure is measured to be −3.899, well outside isotropic stability limit but acceptable for auxetic structures.
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