Autotransplantation Of Teeth Research Articles

Guided Autotransplantation of Teeth: A Novel Method Using Virtually Planned 3-dimensional Templates

IntroductionThe aim of this study was to introduce an innovative method for autotransplantation of teeth using 3-dimensional (3D) surgical templates for guided osteotomy preparation and donor tooth placement. MethodsThis report describes autotransplantation of immature premolars as treatment of an 11-year-old boy having suffered severe trauma with avulsion of permanent maxillary incisors. This approach uses modified methods from guided implant surgery by superimposition of Digital Imaging and Communications in Medicine files and 3D data sets of the jaws in order to predesign 3D printed templates with the aid of a fully digital workflow. ResultsThe intervention in this complex case could successfully be accomplished by performing preplanned virtual transplantations with guided osteotomies to prevent bone loss and ensure accurate donor teeth placement in new recipient sites. Functional and esthetic restoration could be achieved by modifying methods used in guided implant surgery and prosthodontic rehabilitation. The 1-year follow-up showed vital natural teeth with physiological clinical and radiologic parameters. ConclusionsThis innovative approach uses the latest diagnostic methods and techniques of guided implant surgery, enabling the planning and production of 3D printed surgical templates. These accurate virtually predesigned surgical templates could facilitate autotransplantation in the future by full implementation of recommended guidelines, ensuring an atraumatic surgical protocol.

Interdisciplinary index of prosthodontic/substitution orthodontic treatment need for patients with missing teeth.

The need for treatment in cases of missing teeth may result from aesthetic demands or functional impairment, although tooth loss itself does not necessarily constitute a need for prosthetic replacement. In selected cases, restorative treatment can be replaced by tooth autotransplantation or substitution orthodontic treatment. The authors have tried to make an index based not on missing particular teeth, but on the presence of spacing requiring restoration. An attempt has been made to categorize the restorative treatment need. Orthodontic treatment was considered, when it could completely eliminate the need for prosthetic treatment. The proposed classification could be used for assessing eligibility for public refund of restorative or substitution orthodontic treatment, as well as to motivate the patients to have restorations. It should be an individual approach-based decision, which treatment: orthodontic substitution tooth movement or prosthodontic is more cost-effective for the rest of the patient's life.

Tooth Autotransplantation; Clinical Concepts

Dental auto transplantation is defined as the movement of one tooth or dental germ from one position to another, within the same person . Tooth reimplantation and transplantation have a long and difficult history, since both procedures have been carried out for centuries, but failed due to healing complications. This article provides an overview concept of auto transplantation and considerations for clinical success.

Tooth autotransplantation in the anterior maxilla and mandible: retrospective results in young patients

This retrospective study evaluated survival rates, prognosis, and overall success of autotransplanted teeth in young patients missing anterior teeth as a result of trauma, agenesis, or developmental disturbances. Retrospective data were collected from the medical records of patients who had undergone tooth autotransplantations to anterior sites between January 2001 and December 2012. Clinical variables, such as gender, age, surgical indications, donor and recipient sites, type of anesthetics, bone augmentation, and complications during follow-up, were assessed. A total of 59 donor teeth in 46 patients (30 boys and 16 girls; average age 12.15years) were autotransplanted to the anterior region of the maxilla and mandible. After a mean follow-up period of 17.35months (range 10-61months), all of the transplanted teeth remained in situ with no complications. This study supports the autotransplantation of teeth to the anterior alveolus as a viable option suitable in growing patients with missing anterior teeth.

A Novel Approach for Computer-Assisted Template-Guided Autotransplantation of Teeth With Custom 3D Designed/Printed Surgical Tooling. An Ex Vivo Proof of Concept

The aim of this study was to introduce a novel method for accurate autotransplantation with computer-assisted guided templates and assembled custom-designed surgical tooling and to test the feasibility and accuracy of this method exvivo. A partially edentulous human mandibular cadaver was scanned with a cone-beam computed tomography (CBCT) system and an intraoral scan system. The 3-dimensional (3D) data of this cadaver were imported into specialized software and used to analyze the region of the recipient site and the donor tooth was selected. Subsequently, congruent to the donor tooth, custom surgical tools and a surgical guided template were designed and 3D printed. The guided osteotomy was performed and the donor tooth was transplanted. To evaluate the planned position of the donor tooth in relation to the position of the transplanted donor tooth, the mandible with the transplanted donor tooth was rescanned with the CBCT system and software matching was applied to measure the accuracy of the procedure. The angular deflection of the transplanted donor tooth in relation to the planned donor tooth position was 3.1°. When comparing the 3D positions of the shoulder, there was a deviation of 1.25mm and an apical deviation of 0.89mm. With the use of currently available technology, it is feasible to accurately plan and create in a virtual simulation a donor tooth position with congruent custom surgical tools and to transfer this to a clinical setting with 3D printing. However, further research on multiple levels is needed to explore this novel approach.

Autotransplantation donor tooth site harvesting using piezosurgery.

Background:The harvesting of a tooth as a candidate for tooth autotransplantation requires that the delicate dental tissues around the tooth be minimally traumatized. This is especially so for the periradicular tissues of the tooth root and the follicular tissues surrounding the crown. The aim of this report is to describe the use of piezosurgery as an attempt at morbidity reduction in the harvesting of teeth for autotransplantation.Methods:A piezosurgical handpiece and its selection of tips were easily adapted to allow the harvesting and delivery of teeth for autotransplantation purposes.Results:Twenty premolar teeth were harvested using a piezosurgical device. The harvested teeth were subsequently successfully autotransplanted. All twenty teeth healed in a satisfactory manner without excessive mobility or ankyloses.Conclusions:Piezosurgery avoids some of the traumatic aspects of harvesting teeth and removing bone which are associated with thermal damage from the use of conventional rotary instruments or saws. Piezosurgery can be adapted to facilitate the predictable harvesting of teeth for autotransplantation purposes.

Prognostic Factors for Clinical Outcomes in Autotransplantation of Teeth with Complete Root Formation: Survival Analysis for up to 12 Years

IntroductionTooth autotransplantation is a treatment option that has the potential to restore masticatory function and esthetics to edentulous spaces resulting from extracted teeth. The purpose of this study was to investigate the prognostic factors and clinical outcomes for autotransplanted teeth with complete root formation. MethodsPatients who had received tooth autotransplantation in the Department of Conservative Dentistry, Yonsei University Dental Hospital, Seoul, Korea, from July 2001 to August 2010 were electronically searched, and a total of 105 cases of autotransplanted teeth met the inclusion criteria. Tooth survival, inflammatory root resorption (IRR), ankylosis, and related prognostic factors were assessed by using the survival analysis that was based on clinical and radiographic examination. ResultsThe cumulative tooth survival rate was 68.2% at 12 years after the tooth autotransplantation. According to the Cox proportional hazard regression analysis, patient age, donor position, and extraoral time were significantly associated with tooth survival (P < .05). Donor extraction type was significantly associated with IRR (P < .05), and transplantation timing and initial stability were significantly associated with ankylosis (P < .05) ConclusionsPatients less than 45 years of age, maxillary donor teeth, and an extraoral time of less than 15 minutes were associated with significantly higher tooth survival. Surgical extraction of the donor tooth was associated with a significantly higher incidence of IRR. Immediate transplantation after the extraction of the recipient site's tooth and low initial stability were associated with a significantly lower incidence of ankylosis

Retrospective study of 100 autotransplanted teeth with complete root formation and subsequent orthodontic treatment.

Autotransplantation has become a major therapeutic option for replacing missing teeth in adult orthodontic patients. However, little systematic information is available about the long-term stability of autotransplanted teeth with complete root formation after the application of an orthodontic force. The objective of this study was to investigate the outcomes of autotransplanted teeth with complete root formation that underwent orthodontic treatment. One hundred teeth, autotransplanted in 89 patients, were examined over a mean observation period of 5.8 years. Orthodontic force was applied with nickel-titanium wires 4 to 8 weeks after autotransplantation. Root resorption, ankylosis, mobility, pocket depth, and inflammation at the recipient site were investigated clinically and with radiographs. The survival rate of the autotransplanted teeth was 93.0%. Abnormal findings were found in 29 teeth, including 7 lost teeth, for a success rate of 71.0%. Donor tooth type and occlusal condition of the donor tooth before transplantation were associated with abnormal findings. The early application of orthodontic force may increase the success rate of autotransplanted teeth, and the type and presurgical occlusal condition of donor teeth affect the success rate.

OTOTRANSPLANTASYON: VAKA SERİSİ

The purpose of this research is to present the five autotransplantation cases with respect to success rates, prognostic factors, complications and different treatment methods. Three patients’ impacted maxillary canines were extracted and autotransplanted – one of them bilaterally. Two patients underwent mandibular third molar autotransplantation to the sockets of decayed and therefore extracted first molar and second molar. Any perioperative or postoperative complication was seen at autotransplanted teeth which were followed up radiologically and clinically. If the prognostic factors are taken into consideration, autotransplantation is a treatment method that has a high success rate

Validation of cone beam computed tomography–based tooth printing using different three-dimensional printing technologies

Our aim was to determine the accuracy of 3-dimensional reconstructed models of teeth compared with the natural teeth by using 4 different 3-dimensional printers. This in vitro study was carried out using 2 intact, dry adult human mandibles, which were scanned with cone beam computed tomography. Premolars were selected for this study. Dimensional differences between natural teeth and the printed models were evaluated directly by using volumetric differences and indirectly through optical scanning. Analysis of variance, Pearson correlation, and Bland Altman plots were applied for statistical analysis. Volumetric measurements from natural teeth and fabricated models, either by the direct method (the Archimedes principle) or by the indirect method (optical scanning), showed no statistical differences. The mean volume difference ranged between 3.1 mm(3) (0.7%) and 4.4 mm(3) (1.9%) for the direct measurement, and between -1.3 mm(3) (-0.6%) and 11.9 mm(3) (+5.9%) for the optical scan. A surface part comparison analysis showed that 90% of the values revealed a distance deviation within the interval 0 to 0.25 mm. Current results showed a high accuracy of all printed models of teeth compared with natural teeth. This outcome opens perspectives for clinical use of cost-effective 3-dimensional printed teeth for surgical procedures, such as tooth autotransplantation.

Residents' journal review

Residents' journal review

Autotransplantation of odontoma-associated impacted teeth – a novel treatment strategy to meet immediate esthetic demands

Autotransplantation of odontoma-associated impacted teeth – a novel treatment strategy to meet immediate esthetic demands

Pilot study of donor site harvesting with a piezo device to improve tooth autotransplantation

Background: With the development of biodegradable materials, the strength and degradation performances of resorbable plates continue to improve, and resorbable plates are gradually applied in the treatment of midfacial fractures and mandibular fractures. Objectives: To evaluate the results of combined fractures of the mandibular angle and contralateral body or symphysis treated with resorbable plates, and to summarize experiences of the application of resorbable plates. Methods: Eleven patients (5 male and 6 female) with combined fractures of the mandibular angle and contralateral body or symphysis were included in this case series. Open reduction and internal fixation using single or dual resorbable plates by intraoral or extraoral was performed. Postoperatively, follow-up was undertaken to evaluate the fracture healing and the complication of resorbable plates. Findings: Typical granulation tissue and fistula were found around the incision site in two female patients who were treated with single resorbable plate at the mandibular fracture. Other fractures healed without complications during the follow-up period. Conclusions: During the treatment for combined fractures of the mandibular angle and contralateral body or symphysis, the fixation of body or symphysis is prior to the angle. Dual 2.0 mm BioSorb FX resorbable plates fixation of both fracture sites are effective, and resorbable fixation associated with Essig wires are recommended for the fixation of mandibular body or symphysis fractures. In addition, two 2.4 mm BioSorb FX resorbable plates are available for the fixation of mandibular angle fracture when the third molar is extracted.

Do Autotransplanted Teeth Require Elective Root Canal Therapy?

Autotransplant is a viable treatment option when faced with managing a space due to a missing or unerupted tooth. The procedure is less commonly today than in the compared to the past due to the advent of dental implants, however, the latter is not a viable option in the paediatric and adolescent population until the age of 18. Prior to this age, autotransplant is an ideal option either primarily or secondary due to failure of orthodontic management.1,2 The advantages of autotransplant include immediate space filling and maintenance as well as preservation of hard and soft tissue. The general consensus following an autotransplant is that the tooth should undergo root canal therapy (RCT) however the evidence is scant on the issue. This study aimed to review the long-term outcome of autotransplanted teeth and the need for RCT.

Tooth autotransplantations - lessons from animal models: a review

Autotransplantation of teeth is the most natural technique to for replacing missing teeth in exposed parts of the dental arch. Reports from human patients indicate great progress toward successful transplantations. However, complications such as inflammation and ankylosis still occur. To understand regenerative processes after autotransplantations, several animal models have been used (monkeys, rodents, rabbits, cats and dogs) and histological/molecular methods have been established. This review aims to summarise knowledge from animal models and discuss their advantages or disadvantages with respect to possible usage in research.

Autotransplantation of teeth in humans: a systematic review and meta-analysis.

The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. Electronic searches were conducted to identify randomized controlled and prospective clinical trials. Risk of bias within studies was assessed with the Downs and Black tool. Random-effects meta-analyses were conducted to pool the adverse event rates and relative risks with their 95% confidence intervals. Risk of bias across studies was assessed with the GRADE framework followed by sensitivity analyses. Thirty-eight studies were included in the analysis. Reported complications included the need for extraction, failure, hypermobility, pulp necrosis, pulp obliteration, and root resorption. Pooled complication event rates varied considerably, with small studies (<100 teeth) reporting greater complication rates. The analysis of risk factors was associated with both the primary outcome (extraction need) and secondary outcomes (failure, hypermobility, pulp necrosis, pulp obliteration, root resorption). The stage of root development seems to influence both the future survival, as well as the success of the transplanted teeth. Teeth with open apex were less likely to be extracted in comparison to teeth with closed apex (3 studies; 413 teeth; relative risk 0.3; 95% confidence interval 0.2-0.6). Due to the small number of the contributing studies, their methodological limitations, and the heterogeneous results reported, no firm conclusions can be drawn. Root development of the donor teeth has been established as one the most important factor related to the success of tooth autotransplantation.

Vertical Bone Growth after Autotransplantation of Mature Third Molars: 2 Case Reports with Long-term Follow-up

Tooth autotransplantation is a viable treatment option for tooth replacement when a suitable donor tooth is available. These case reports described significant vertical bone growth after autotransplantation of a mature third molar. The left mandible third molars (n = 2) were transplanted to the missing tooth in the left mandible. The patient follow-up period was 10 years after transplantation. Clinical examination revealed no mobility of the transplanted tooth. Radiographic examination indicated that bone regeneration occurred around the transplanted tooth. Vertical bone growth was observed in the cervical area of the root surface and the recipient bone. In autotransplantation of mature teeth, long-term follow-up results indicate that vertical bone growth can be expected if viability of the periodontal ligament cells is maintained.

Post-Odontoma autotransplantation of an impacted tooth: A case report

After years of relegation by dental implants, autotransplantation has recently become more popular because of a better understanding of its science. The prognosis of autotransplantation primarily depends upon the presence of an intact alveolar bone at the transplant site and the regeneration of a functional periodontal ligament of the transplant. Replacement of an unsalvaged or a missing tooth by a natural tooth with normal periodontium within a short duration of treatment is the ultimate challenge of autotransplantation. Meanwhile, Platelet Rich Fibrin (PRF) is popular as a biomaterial which helps in the regeneration of bone and periodontal tissues. To improve the prognosis, and also shorten the treatment time in a rare case of autotransplantation of an impacted tooth in a post-odontoma site, we did a two-stage surgical procedure aided by synthetic bone granules (Biograft) and PRF. The clinical and radiological findings at 6 months follow-up showed good result and promise.

Teeth Bank - Autotransplantation of tooth-

Teeth Bank - Autotransplantation of tooth-

Autotransplantation of an impacted mandibular third molar to replace a severely impacted mandibular second molar: A borderline case

The alveolar bone support around the transplanted tooth, the stage of root development and apical closure are accepted as basic clinical factors that affect the success of tooth transplantation. Due to its high failure ratio, tooth transplantation is not common in the field of dentistry; however, major advantages of the technique such as continuing physiological root development, formation of interdental papilla, and rapid generation of alveolar bone with a lower cost should be considered. The aim of this report was to present autotransplantation of a third molar into adjacent deep-impacted second molar extraction socket without sufficient alveolar bone support. A 15-year-old healthy male patient referred to Department of Orthodontics due to dental crowding. For left mandibular quadrant, it was multidisciplinary planned to surgical removal of deep-impacted vertically positioned second molar and adjacent impacted mesioangular third molar was re-implanted to its extraction socket. Patient was followed for 4 years; clinical and radiological results were thoroughly sufficient. Even in this borderline case where there is only alveolar bone support on lingual site, autotransplanted tooth can survive successfully.