In 2004, the Central Institute of Forensic Science (CIFS) established a DNA database. The DNA database was originally utilized as intelligence to support law enforcement agencies solving organized crimes in the Deep South of Thailand. This area covers three border provinces of Thailand and Malaysia. There were 1600 hits from various incidents of this area. Recently, additional offences are being kept in the CIFS DNA database such as homicide, murder, sexual assault, burglary and drug smuggling. Until March 2017, the CIFS DNA database contains approximately 145,000 DNA profiles including 130,000 profiles of individuals (potential suspects and prisoners) and 14,000 profiles from crime stain samples. Mainly autosomal STR markers were collected in the DNA database. Y-STR markers are also analyzed and uploaded, especially crime stains from sexual assault cases and their potential suspects. Other 200 hits were reported on other offences such as homicide, sexual assault, and drug smuggling. Almost 2000 hits were found and reported to law enforcement agencies. CIFS plans to expand the capabilities of DNA investigations such as collecting newly registered prisoners and all prisoners in Thailand in order to monitor serial offense and increase the hit rate. CIFS DNA database also plans to work on DNA searching and data exchange with national and international law enforcement agencies. An ultimate goal of DNA database is to help to solve transnational crimes such as human trafficking, migrant smuggling, and illegal labors.