Autonomous Fourier Ptychographic Microscopy (FPM) is a technology widely used in the field of pathology. It is compatible with high resolution and large field-of-view imaging and can observe more image details. Red blood cells play an indispensable role in assessing the oxygen-carrying capacity of the human body and in screening for clinical diagnosis and treatment needs. In this paper, the blood cell data set is constructed based on the FPM system experimental platform. Before training, four enhancement strategies are adopted for the blood cell image data to improve the generalization and robustness of the model. A blood cell detection algorithm based on SCD-YOLOv7 is proposed. Firstly, the C-MP (Convolutional Max Pooling) module and DELAN (Deep Efficient Learning Automotive Network) module are used in the feature extraction network to optimize the feature extraction process and improve the extraction ability of overlapping cell features by considering the characteristics of channels and spatial dimensions. Secondly, through the Sim-Head detection head, the global information of the deep feature map (mean average precision) and the local details of the shallow feature map are fully utilized to improve the performance of the algorithm for small target detection. MAP is a comprehensive indicator for evaluating the performance of object detection algorithms, which measures the accuracy and robustness of a model by calculating the average precision (AP) under different categories or thresholds. Finally, the Focal-EIoU (Focal Extended Intersection over Union) loss function is introduced, which not only improves the convergence speed of the model but also significantly improves the accuracy of blood cell detection. Through quantitative and qualitative analysis of ablation experiments and comparative experimental results, the detection accuracy of the SCD-YOLOv7 algorithm on the blood cell data set reached 92.4%, increased by 7.2%, and the calculation amount was reduced by 14.6 G.
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