We study modules which are characteristic submodules in their injective hulls. The author is supported by the Russian Foundation for Basic Research, project 08-01- 00693-a All rings below are assumed to be associative and with nonzero identity ele- ment; all modules are assumed to be unitary. A moduleM is said to be Noetherian if every properly ascending chain of submodules in M is finite. Expressions of the form 'A is a Noetherian ring' mean that AA and AA are Noetherian modules. A moduleM is said to be injective with respect to the moduleX or X-injective if for any submodule X1 in X, every homomorphismX1 → M may be extended to a homomorphismX → M. For a ring A, an A-module M is said to be injective if M is injective with respect to any A-module. A submodule M of the module E is said to be essential if M ∩ E1 6 0 for any nonzero submodule E1 in E. If E is an injective module and M is an essential submodule in E then E is called the injective hull of the module M. The injective hull is unique up to isomorphism. A submoduleM of the module E is called a characteristic submodule if f(M) ⊆ M for every automorphismf of the module E. In the papers (3), (8), and (10), a module M is said to be automorphism- invariant if M is a characteristic submodule of the injective hull of M. It is easy to verify that a module M is an automorphism-invariant if and only if M is a charac- teristic submodule of some injective module; see Remark 6 below. Remark 1. In (3, Theorem 16), it is proved that a module M is an automorphism-invariant module if and only if M is a pseudo-injective module, i.e., for any submodule X in M , every monomorphism X → M may be exten- ded to an endomorphism of the moduleM . For example, see (6), (11), (3) about pseudo-injective modules. Remark 2. It is clear that every injective module is an automorphism-invariant module. The converse is not true, since every simple Abelian group is a finite automorphism-invariant non-injective module over the ring of integers Z.