Different experiential traces (i.e., linguistic, motor, and perceptual) are likely contributing to the organization of human semantic knowledge. Here, we aimed to address this issue by investigating whether visual experience may affect the sensitivity to distributional priors from natural language. We conducted an independent reanalysis of data from Bottini et al., in which early blind and sighted participants performed an auditory lexical decision task. Since previous research has shown that semantic neighborhood density-the mean distance between a target word and its closest semantic neighbors-can influence performance in lexical decision tasks, we investigated whether vision may alter the reliance on this semantic index. We demonstrate that early blind participants are more sensitive to semantic neighborhood density than sighted participants, as indicated by the significantly faster response times for words with higher levels of semantic neighborhood density shown by the blind group. These findings suggest that an early lack of visual experience may lead to enhanced sensitivity to the distributional history of words in natural language, deepening in turn our understanding of the strict interplay between linguistic and perceptual experience in the organization of conceptual knowledge.