Auditory Domain Research Articles

Variance aftereffect within and between sensory modalities for visual and auditory domains.

We can grasp various features of the outside world using summary statistics efficiently. Among these statistics, variance is an index of information homogeneity or reliability. Previous research has shown that visual variance information in the context of spatial integration is encoded directly as a unique feature, and currently perceived variance can be distorted by that of the preceding stimuli. In this study, we focused on variance perception in temporal integration. We investigated whether any variance aftereffects occurred in visual size and auditory pitch. Furthermore, to examine the mechanism of cross-modal variance perception, we also investigated whether variance aftereffects occur between different modalities. Four experimental conditions (a combination of sensory modalities of adaptor and test: visual-to-visual, visual-to-auditory, auditory-to-auditory, and auditory-to-visual) were conducted. Participants observed a sequence of visual or auditory stimuli perturbed in size or pitch with certain variance and performed a variance classification task before and after the variance adaptation phase. We found that in visual size, within modality adaptation to small or large variance, resulted in a variance aftereffect, indicating that variance judgments are biased in the direction away from that of the adapting stimulus. In auditory pitch, within modality adaptation to small variance caused variance aftereffect. For cross-modal combinations, adaptation to small variance in visual size resulted in variance aftereffect. However, the effect was weak, and variance aftereffect did not occur in other conditions. These findings indicate that the variance information of sequentially presented stimuli is encoded independently in visual and auditory domains.

Revealing the stimulus-driven component of attention through modulations of auditory salience by timbre attributes

Attention allows the listener to select relevant information from their environment, and disregard what is irrelevant. However, irrelevant stimuli sometimes manage to capture it and stand out from a scene because of bottom-up processes driven by salient stimuli. This attentional capture effect was observed using an implicit approach based on the additional singleton paradigm. In the auditory domain, it was shown that sound attributes such as intensity and frequency tend to capture attention during auditory search (cost to performance) for targets defined on a different dimension such as duration. In the present study, the authors examined whether a similar phenomenon occurs for attributes of timbre such as brightness (related to the spectral centroid) and roughness (related the amplitude modulation depth). More specifically, we revealed the relationship between the variations of these attributes and the magnitude of the attentional capture effect. In experiment 1, the occurrence of a brighter sound (higher spectral centroid) embedded in sequences of successive tones produced significant search costs. In experiments 2 and 3, different values of brightness and roughness confirmed that attention capture is monotonically driven by the sound features. In experiment 4, the effect was found to be symmetrical: positive or negative, the same difference in brightness had the same negative effect on performance. Experiment 5 suggested that the effect produced by the variations of the two attributes is additive. This work provides a methodology for quantifying the bottom-up component of attention and brings new insights on attention capture and auditory salience.

Moderate associations between BDNF Val66Met gene polymorphism, musical expertise, and mismatch negativity

Auditory predictive processing relies on a complex interaction between environmental, neurophysiological, and genetic factors. In this view, the mismatch negativity (MMN) and intensive training on a musical instrument for several years have been used for studying environment-driven neural adaptations in audition. In addition, brain-derived neurotrophic factor (BDNF) has been shown crucial for both the neurogenesis and the later adaptation of the auditory system. The functional single-nucleotide polymorphism (SNP) Val66Met (rs6265) in the BDNF gene can affect BDNF protein levels, which are involved in neurobiological and neurophysiological processes such as neurogenesis and neuronal plasticity. In this study, we hypothesised that genetic variation within the BDNF gene would be associated with different levels of neuroplasticity of the auditory cortex in 74 musically trained participants. To achieve this goal, musicians and non-musicians were recruited and divided in Val/Val and Met- (Val/Met and Met/Met) carriers and their brain activity was measured with magnetoencephalography (MEG) while they listened to a regular auditory sequence eliciting different types of prediction errors. MMN responses indexing those prediction errors were overall enhanced in Val/Val carriers who underwent intensive musical training, compared to Met-carriers and non-musicians with either genotype. Although this study calls for replications with larger samples, our results provide a first glimpse of the possible role of gene-regulated neurotrophic factors in the neural adaptations of automatic predictive processing in the auditory domain after long-term training.

EmoSex: Emotion prevails over sex in implicit judgments of faces and voices.

Appraisals can be influenced by cultural beliefs and stereotypes. In line with this, past research has shown that judgments about the emotional expression of a face are influenced by the face's sex, and vice versa that judgments about the sex of a person somewhat depend on the person's facial expression. For example, participants associate anger with male faces, and female faces with happiness or sadness. However, the strength and the bidirectionality of these effects remain debated. Moreover, the interplay of a stimulus' emotion and sex remains mostly unknown in the auditory domain. To investigate these questions, we created a novel stimulus set of 121 avatar faces and 121 human voices (available at https://bit.ly/2JkXrpy) with matched, fine-scale changes along the emotional (happy to angry) and sexual (male to female) dimensions. In a first experiment (N = 76), we found clear evidence for the mutual influence of facial emotion and sex cues on ratings, and moreover for larger implicit (task-irrelevant) effects of stimulus' emotion than of sex. These findings were replicated and extended in two preregistered studies-one laboratory categorization study using the same face stimuli (N = 108; https://osf.io/ve9an), and one online study with vocalizations (N = 72; https://osf.io/vhc9g). Overall, results show that the associations of maleness-anger and femaleness-happiness exist across sensory modalities, and suggest that emotions expressed in the face and voice cannot be entirely disregarded, even when attention is mainly focused on determining stimulus' sex. We discuss the relevance of these findings for cognitive and neural models of face and voice processing. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Network-Based Differences in Top-Down Multisensory Integration between Adult ADHD and Healthy Controls-A Diffusion MRI Study.

Attention-deficit-hyperactivity disorder (ADHD) is a neurodevelopmental disorder neurobiologically conceptualized as a network disorder in white and gray matter. A relatively new branch in ADHD research is sensory processing. Here, altered sensory processing i.e., sensory hypersensitivity, is reported, especially in the auditory domain. However, our perception is driven by a complex interplay across different sensory modalities. Our brain is specialized in binding those different sensory modalities to a unified percept-a process called multisensory integration (MI) that is mediated through fronto-temporal and fronto-parietal networks. MI has been recently described to be impaired for complex stimuli in adult patients with ADHD. The current study relates MI in adult ADHD with diffusion-weighted imaging. Connectome-based and graph-theoretic analysis was applied to investigate a possible relationship between the ability to integrate multimodal input and network-based ADHD pathophysiology. Multishell, high-angular resolution diffusion-weighted imaging was performed on twenty-five patients with ADHD (six females, age: 30.08 (SD: 9.3) years) and twenty-four healthy controls (nine females; age: 26.88 (SD: 6.3) years). Structural connectome was created and graph theory was applied to investigate ADHD pathophysiology. Additionally, MI scores, i.e., the percentage of successful multisensory integration derived from the McGurk paradigm, were groupwise correlated with the structural connectome. Structural connectivity was elevated in patients with ADHD in network hubs mirroring altered default-mode network activity typically reported for patients with ADHD. Compared to controls, MI was associated with higher connectivity in ADHD between Heschl's gyrus and auditory parabelt regions along with altered fronto-temporal network integrity. Alterations in structural network integrity in adult ADHD can be extended to multisensory behavior. MI and the respective network integration in ADHD might represent the maturational cortical delay that extends to adulthood with respect to sensory processing.

Auditory Domain Sensitivity and Neuroplasticity-Based Targeted Cognitive Training in Autism Spectrum Disorder

Sensory processing, along with the integration of external inputs into stable representations of the environment, is integral to social cognitive functioning; challenges in these processes have been reported in Autism Spectrum Disorder (ASD) since the earliest descriptions of autism. Recently, neuroplasticity-based targeted cognitive training (TCT) has shown promise as an approach to improve functional impairments in clinical patients. However, few computerized and adaptive brain-based programs have been trialed in ASD. For individuals with sensory processing sensitivities (SPS), the inclusion of some auditory components in TCT protocols may be aversive. Thus, with the goal of developing a web-based, remotely accessible intervention that incorporates SPS concerns in the auditory domain, we assessed auditory SPS in autistic adolescents and young adults (N = 25) who started a novel, computerized auditory-based TCT program designed to improve working memory and information processing speed and accuracy. We found within-subject gains across the training program and between pre/post-intervention assessments. We also identified auditory, clinical, and cognitive characteristics that are associated with TCT outcomes and program engagement. These initial findings may be used to inform therapeutic decisions about which individuals would more likely engage in and benefit from an auditory-based, computerized TCT program.

A new tool for the assessment of speech understanding and spatial hearing difficulties in children: the Kid-SSQ questionnaire.

To develop and validate a new questionnaire, the Kid-SSQ, for the rapid screening of hearing abilities in children with hearing impairment, aged 7-17years. The questionnaire was constructed from two existing, validated versions of the 'Speech, Spatial and Qualities of Hearing'-(SSQ) questionnaire (pediatric form and adult short-form). The 12 selected items included auditory aspects from three subscales: speech perception, spatial hearing, and qualities of hearing. This new short form was then validated in 154 children with cochlear implants (100 bilaterally, and 54 unilaterally implanted children). Construct validity was assessed by testing relationships between Kid-SSQ scores and objective clinical parameters (e.g., age at test, pure-tone audiometry-PTA threshold, speech reception threshold-SRT, duration of binaural experience). Completion time was acceptable for use with children (less than 10min) and the non-response rate was less than 1%. Good internal consistency was obtained (Cronbach's α = 0.78), with a stable internal structure corresponding to the 3 intended subscales. External validity showed the specificity of each subscale: speech subscale scores were significantly predicted (r = 0.32, p < 0.001) by both 2kHz PTA threshold (β = 0.33, p < 0.001) and SRT (β = - 0.23, p < 0.001). Children with more binaural experience showed significantly higher scores on the spatial subscale than children with less binaural experience (F(1,98) = 5.1, p < 0.03) and the qualities of hearing subscale scores significantly depended on both age and SRT (r = 0.32, p < 0.001). The Kid-SSQ questionnaire is a robust and clinically useful questionnaire for self-assessment of difficulties in various auditory domains.

Diminished Repetition Suppression Reveals Selective and Systems-Level Face Processing Differences in ASD.

Repeated exposure to a stimulus results in reduced neural response, or repetition suppression, in brain regions responsible for processing that stimulus. This rapid accommodation to repetition is thought to underlie learning, stimulus selectivity, and strengthening of perceptual expectations. Importantly, reduced sensitivity to repetition has been identified in several neurodevelopmental, learning, and psychiatric disorders, including autism spectrum disorder (ASD), a neurodevelopmental disorder characterized by challenges in social communication and repetitive behaviors and restricted interests. Reduced ability to exploit or learn from repetition in ASD is hypothesized to contribute to sensory hypersensitivities, and parallels several theoretical frameworks claiming that ASD individuals show difficulty using regularities in the environment to facilitate behavior. Using fMRI in autistic and neurotypical human adults (females and males), we assessed the status of repetition suppression across two modalities (vision, audition) and with four stimulus categories (faces, objects, printed words, and spoken words). ASD individuals showed domain-specific reductions in repetition suppression for face stimuli only, but not for objects, printed words, or spoken words. Reduced repetition suppression for faces was associated with greater challenges in social communication in ASD. We also found altered functional connectivity between atypically adapting cortical regions and higher-order face recognition regions, and microstructural differences in related white matter tracts in ASD. These results suggest that fundamental neural mechanisms and system-wide circuits are selectively altered for face processing in ASD and enhance our understanding of how disruptions in the formation of stable face representations may relate to higher-order social communication processes.SIGNIFICANCE STATEMENT A common finding in neuroscience is that repetition results in plasticity in stimulus-specific processing regions, reflecting selectivity and adaptation (repetition suppression [RS]). RS is reduced in several neurodevelopmental and psychiatric conditions including autism spectrum disorder (ASD). Theoretical frameworks of ASD posit that reduced adaptation may contribute to associated challenges in social communication and sensory processing. However, the scope of RS differences in ASD is unknown. We examined RS for multiple categories across visual and auditory domains (faces, objects, printed words, spoken words) in autistic and neurotypical individuals. We found reduced RS in ASD for face stimuli only and altered functional connectivity and white matter microstructure between cortical face-recognition areas. RS magnitude correlated with social communication challenges among autistic individuals.

Prevalence of multisensory hallucinations in people at risk of transition to psychosis

Hallucinations can occur in single or multiple sensory modalities. Greater attention has been paid to single sensory experiences with a comparative neglect of hallucinations that occur across two or more sensory modalities (multisensory hallucinations). This study explored how common these experiences were in people at risk of transition to psychosis (n=105) and considered whether a greater number of hallucinatory experiences increased delusional ideation and reduced functioning, both of which are associated with a greater risk of transition to psychosis. Participants reported a range of unusual sensory experiences, with two or three being common. However, when a strict definition of hallucinations was applied, in which the experience has the quality of a real perception and in which the person believes them to be real experiences, then multisensory experiences were rare and when reported, single sensory hallucinations in the auditory domain were most common. The number of unusual sensory experiences or hallucinations was not significantly associated with greater delusional ideation or poorer functioning. Theoretical and clinical implications are discussed.

Seeing Auditory Object: Pupillary Light Response Reflects Covert Attention to Auditory Space and Object.

Attention to the relevant object and space is the brain's strategy to effectively process the information of interest in complex environments with limited neural resources. Numerous studies have documented how attention is allocated in the visual domain, whereas the nature of attention in the auditory domain has been much less explored. Here, we show that the pupillary light response can serve as a physiological index of auditory attentional shift and can be used to probe the relationship between space-based and object-based attention as well. Experiments demonstrated that the pupillary response corresponds to the luminance condition where the attended auditory object (e.g., spoken sentence) was located, regardless of whether attention was directed by a spatial (left or right) or nonspatial (e.g., the gender of the talker) cue and regardless of whether the sound was presented via headphones or loudspeakers. These effects on the pupillary light response could not be accounted for as a consequence of small (although observable) biases in gaze position drifting. The overall results imply a unified audiovisual representation of spatial attention. Auditory object-based attention contains the space representation of the attended auditory object, even when the object is oriented without explicit spatial guidance.

Intelligence and Visual Mismatch Negativity: Is Pre-Attentive Visual Discrimination Related to General Cognitive Ability?

EEG has been used for decades to identify neurocognitive processes related to intelligence. Evidence is accumulating for associations with neural markers of higher-order cognitive processes (e.g., working memory); however, whether associations are specific to complex processes or also relate to earlier processing stages remains unclear. Addressing these issues has implications for improving our understanding of intelligence and its neural correlates. The MMN is an ERP that is elicited when, within a series of frequent standard stimuli, rare deviant stimuli are presented. As stimuli are typically presented outside the focus of attention, the MMN is suggested to capture automatic pre-attentive discrimination processes. However, the MMN and its relation to intelligence has largely only been studied in the auditory domain, thus preventing conclusions about the involvement of automatic discrimination processes in humans' dominant sensory modality-vision. EEG was recorded from 50 healthy participants during a passive visual oddball task that presented simple sequence violations and deviations within a more complex hidden pattern. Signed area amplitudes and fractional area latencies of the visual MMN were calculated with and without Laplacian transformation. Correlations between visual MMN and intelligence (Raven's Advanced Progressive Matrices) were of negligible to small effect sizes, differed critically between measurement approaches, and Bayes Factors provided anecdotal to substantial evidence for the absence of an association. We discuss differences between the auditory and visual MMN, the implications of different measurement approaches, and offer recommendations for further research in this evolving field.

Individual theta-band cortical entrainment to speech in quiet predicts word-in-noise comprehension.

Speech elicits brain activity time-locked to its amplitude envelope. The resulting speech-brain synchrony (SBS) is thought to be crucial to speech parsing and comprehension. It has been shown that higher speech-brain coherence is associated with increased speech intelligibility. However, studies depending on the experimental manipulation of speech stimuli do not allow conclusion about the causality of the observed tracking. Here, we investigate whether individual differences in the intrinsic propensity to track the speech envelope when listening to speech-in-quiet is predictive of individual differences in speech-recognition-in-noise, in an independent task. We evaluated the cerebral tracking of speech in source-localized magnetoencephalography, at timescales corresponding to the phrases, words, syllables and phonemes. We found that individual differences in syllabic tracking in right superior temporal gyrus and in left middle temporal gyrus (MTG) were positively associated with recognition accuracy in an independent words-in-noise task. Furthermore, directed connectivity analysis showed that this relationship is partially mediated by top-down connectivity from premotor cortex-associated with speech processing and active sensing in the auditory domain-to left MTG. Thus, the extent of SBS-even during clear speech-reflects an active mechanism of the speech processing system that may confer resilience to noise.

Validation of Music Therapy Assessment Tool for Awareness in Disorders of Consciousness (MATADOC) with CRS-R

<h3>Research Objectives</h3> To examine the concurrent validity of the MATADOC with the criterion standard Coma Recovery Scale (CRS-R) for diagnostic outcomes of awareness To explore the function of comparable MATADOC items and CRS-R function scales across similar domains (e.g. auditory, visual). <h3>Design</h3> Prospective multisite cohort study collected concurrent MATADOC and CRS-R data using repeated measures with patients with disorders of consciousness (DOC). Raters were blinded. <h3>Setting</h3> Three specialist inpatient rehabilitation units for DOC (US, UK, Ireland). <h3>Participants</h3> 74 adults with prolonged DOC stemming from acquired brain injury recruited using convenience sampling. <h3>Interventions</h3> The MATADOC protocol elicits behavioral responsiveness using live music in five tasks during four clinical contacts of 15-30 minutes duration (60-120 mins total). Observed behavioral responses are rated across motor, communication, arousal, visual and auditory domains using a 14-item measure. Pre and post observation period records spontaneous behaviors. The CRS-R protocol delivers tasks in the motor, visual, auditory and communication domains in clinical contacts of 15-30 minutes duration (60 – 120 minutes in total for 4 contacts). Observed responses are rated in six function scales. <h3>Main Outcome Measures</h3> Two measures of awareness: MATADOC and CRS-R. <h3>Results</h3> Fair (Cohen's kappa or "k"=0.238, p=.006) ranging to moderate (k=0.419, p<.001) significant agreement found between CRS-R and MATADOC diagnostic outcomes for each contact, with significant correlations between scores (mean Pearson = 0.721, p<.001). Agreement increased over repeated contacts. Moderate agreement found for overall diagnostic outcomes ranging across VS, MCS and EMCS (k=0.397, p<.001). Moderate significant agreement found between measures for motor scores (k=.556, p<.001) and visual outcomes (mean k=0.326). No agreement was found for item outcomes assessing auditory responsiveness. <h3>Conclusions</h3> The MATADOC complements the CRS-R in treatment planning for DOC. MATADOC measures of auditory responsiveness suggest musical stimuli may elicit more complex behaviors than non-music protocols. The MATADOC rates complexity of auditory localization as MCS in line with recent recommendations which may explain diagnostic outcome differences with CRS-R outcomes. <h3>Author(s) Disclosures</h3> None.

Prevalence and nature of multi-sensory and multi-modal hallucinations in people with first episode psychosis

Hallucinations can occur in single or multiple sensory modalities. This study explored how common these experiences were in people with first episode of psychosis (n = 82). Particular attention was paid to the number of modalities reported and whether the experiences were seen to be linked temporally and thematically. It was predicted that those people reporting a greater number of hallucinations would report more delusional ideation, greater levels of distress generally and lower functioning. All participants reported hallucinations in the auditory domain, given the nature of the recruitment. The participants also reported a range of other unusual sensory experiences, with visual and tactile hallucinations being reported by over half. Moreover, single sensory experiences or unimodal hallucinations were less common than two or more hallucination modalities which was reported by 78% of the participants. The number of hallucinations was significantly associated with greater delusional ideation and higher levels of general distress, but not with reduced functioning. It is clear there is a need to refine psychological treatments so that they are better matched to the actual experiences reported by people with psychosis. Theoretical implications are also considered.

Acute and Repeated Administration of NLX-101, a Selective Serotonin-1A Receptor Biased Agonist, Reduces Audiogenic Seizures in Developing Fmr1 Knockout Mice

Fragile XSyndrome (FXS) is a leading known genetic cause of Autism Spectrum Disorders (ASD) and intellectual disability. A consistent and debilitating phenotype of FXS is sensory hypersensitivity that manifests strongly in the auditory domain and may lead to delayed language and high anxiety. The mouse model of FXS, the Fmr1 KO mouse, also shows auditory hypersensitivity, an extreme form of which is seen as audiogenic seizures (AGS). The midbrain inferior colliculus (IC) is critically involved in generating audiogenic seizures and IC neurons are hyper-responsive to sounds in developing Fmr1 KO mice. Serotonin-1A receptor (5-HT1A) activation reduces IC activity. Therefore, we tested whether 5-HT1A activation is sufficient to reduce audiogenic seizures in Fmr1 KO mice. A selective and post-synaptic 5-HT1A receptor biased agonist, 3-Chloro-4-fluorophenyl-[4-fluoro-4-[[(5-methylpyrimidin-2-ylmethyl)amino]methyl]piperidin-1-yl] methanone (NLX-101, 0.6, 1.2, 1.8 or 2.4 mg/kg, i.p.) was administered to Fmr1 KO mice 15 min before seizure induction. Whereas the 0.6 mg/kg dose was ineffective in reducing seizures, the 1.2, 1.8 and 2.4 mg/kg doses of NLX-101 dramatically reduced seizures and increased mouse survival. Treatment with a combination of NLX-101 and 5-HT1A receptor antagonists prevented the protective effects of NLX-101, indicating that NLX-101 acts selectively through 5-HT1A receptors to reduce audiogenic seizures. NLX-101 (1.8 mg/kg) was still strongly effective in reducing seizures even after repeated administration over 5 days, suggesting an absence of tachyphylaxis to the effects of the compound. Together, these studies point to a promising treatment option targeting post-synaptic 5-HT1A receptors to reduce auditory hypersensitivity in FXS, and potentially across autism spectrum disorders.

Gamma-band entrainment abnormalities in schizophrenia: Modality-specific or cortex-wide impairment?

A growing body of literature suggests that cognitive impairment in people with schizophrenia (PSZ) results from disrupted cortical excitatory/inhibitory (E-I) balance, which may be linked to gamma entrainment and can be measured noninvasively using electroencephalography (EEG). However, it is not yet known the degree to which these entrainment abnormalities covary within subjects across sensory modalities. Furthermore, the degree to which cross-modal gamma entrainment reflects variation in biological processes associated with cognitive performance remains unclear. We used EEG to measure entrainment to repetitive auditory and visual stimulation at beta (20 Hz) and gamma (30 and 40 Hz) frequencies in PSZ (n = 78) and healthy control subjects (HCS; n = 80). Three indices were measured for each frequency and modality: event-related spectral perturbation (ERSP), intertrial coherence (ITC), and phase-lag angle (PLA). Cognition and symptom severity were also assessed. We found little evidence that gamma entrainment covaried across sensory modalities. PSZ exhibited a modest correlation between modalities at 40 Hz for ERSP and ITC measures (r = 0.23-0.24); however, no other significant correlations between modalities emerged for either HCS or PSZ. Both univariate and multivariate analyses revealed that (a) the pattern of entrainment abnormalities in PSZ differed across modalities, and (b) modality rather than frequency band was the main source of variance. Finally, we observed a significant association between cognition and gamma entrainment in the auditory domain only in HCS. Gamma-band EEG entrainment does not reflect a unitary transcortical mechanism but is instead modality specific. To the extent that entrainment reflects the integrity of cortical E-I balance, the deficits observed in PSZ appear to be modality specific and not consistently associated with cognitive impairment. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Attentional modulations of audiovisual interactions in apparent motion: Temporal ventriloquism effects on perceived visual speed.

The timing of brief stationary sounds has been shown to alter different aspects of visual motion, such as speed estimation. These effects of auditory timing have been explained by temporal ventriloquism and auditory dominance over visual information in the temporal domain. Although previous studies provide unprecedented evidence for the multisensory nature of speed estimation, how attention is involved in these audiovisual interactions remains unclear. Here, we aimed to understand the effects of spatial attention on these audiovisual interactions in time. We utilized a set of audiovisual stimuli that elicit temporal ventriloquism in visual apparent motion and asked participants to perform a speed comparison task. We manipulated attention either in the visual or auditory domain and systematically changed the number of moving objects in the visual field. When attention was diverted to a stationary object in the visual field via a secondary task, the temporal ventriloquism effects on perceived speed decreased. On the other hand, focusing attention on the auditory stimuli facilitated these effects consistently across different difficulty levels of secondary auditory task. Moreover, the effects of auditory timing on perceived speed did not change with the number of moving objects and existed in all the experimental conditions. Taken together, our findings revealed differential effects of allocating attentional resources in the visual and auditory domains. These behavioral results also demonstrate that reliable temporal ventriloquism effects on visual motion can be induced even in the presence of multiple moving objects in the visual field and under different perceptual load conditions.

Cross-modal generalization of value-based attentional priority.

This study aimed to determine whether value-based attentional biases learned in the auditory domain can correspondingly shape visual attention. A learning phase established associations between auditory words and monetary rewards via a modified version of the dichotic listening task. In a subsequent test phase, participants performed a Stroop task including written representations of auditory words previously paired with reward and semantic associates of formerly rewarded words. Results support a semantic generalization of value-driven attention from the auditory to the visual domain. The findings provide valuable insight into a critical aspect of adaptation and the understanding of maladaptive behaviors (e.g., addiction).

The phenomenology of auditory verbal hallucinations in schizophrenia and the challenge from pseudohallucinations.

In trying to make sense of the extensive phenomenological variation of first-personal reports on auditory verbal hallucinations, the concept of pseudohallucination is originally introduced to designate any hallucinatory-like phenomena not exhibiting some of the paradigmatic features of “genuine” hallucinations. After its introduction, Karl Jaspers locates the notion of pseudohallucinations into the auditory domain, appealing to a distinction between hallucinatory voices heard within the subjective inner space (pseudohallucination) and voices heard in the outer external space (real hallucinations) with differences in their sensory richness. Jaspers' characterization of the term has been the target of a number of phenomenological, conceptual and empirically-based criticisms. From this latter point of view, it has been claimed that the concept cannot capture distinct phenomena at the neurobiological level. Over the last years, the notion of pseudohallucination seems to be falling into disuse as no major diagnostic system seems to refer to it. In this paper, we propose that even if the concept of pseudohallucination is not helpful to differentiate distinct phenomena at the neurobiological level, the inner/outer distinction highlighted by Jaspers' characterization of the term still remains an open explanatory challenge for dominant theories about the neurocognitive origin of auditory verbal hallucinations. We call this, “the challenge from pseudohallucinations”. After exploring this issue in detail, we propose some phenomenological, conceptual, and empirical paths for future research that might help to build up a more contextualized and dynamic view of auditory verbal hallucinatory phenomena.

Hierarchical processing underpins competition in tactile perceptual bistability

Ambiguous sensory information can lead to spontaneous alternations between perceptual states, recently shown to extend to tactile perception. The authors recently proposed a simplified form of tactile rivalry which evokes two competing percepts for a fixed difference in input amplitudes across antiphase, pulsatile stimulation of the left and right fingers. This study addresses the need for a tactile rivalry model that captures the dynamics of perceptual alternations and that incorporates the structure of the somatosensory system. The model features hierarchical processing with two stages. The first and the second stages of model could be located at the secondary somatosensory cortex (area S2), or in higher areas driven by S2. The model captures dynamical features specific to the tactile rivalry percepts and produces general characteristics of perceptual rivalry: input strength dependence of dominance times (Levelt’s proposition II), short-tailed skewness of dominance time distributions and the ratio of distribution moments. The presented modelling work leads to experimentally testable predictions. The same hierarchical model could generalise to account for percept formation, competition and alternations for bistable stimuli that involve pulsatile inputs from the visual and auditory domains.