Examination of various bone sections of edentulous atrophic mandibles showed that the body of the mandible loses up to 60% of its original bone substance during progressive atrophy. Most of the bone loss occurs in a relatively early stage of the atrophic process. The greatest extent of bone reduction can be observed in the area of the second premolar and the first molar. In the interforaminal region, which is situated mesial from them, resorption, in most cases, is not as progressive as in the premolar/molar area. The compact and cancellous bone substances are most often equally affected by resorption. Moreover, it could be observed that the cancellous bone substance of extremely atrophic mandibles particularly in the interforaminal region, is marked by a significant increase in density. This might be interpreted as a restructuring process to compensate for bone losses and to secure the stability of the atrophic body of the mandible.
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