Asymmetric Flow Pattern Research Articles

Investigation on flame behaviors in the mesoscale channel of one sudden-expansion step during the preliminary stage of ignition

The dynamic flame behaviors at the preliminary stage of ignition in the mesoscale sudden-expansion channel are numerically investigated in this study under the isothermal condition (300 K) at walls by using a two-dimensional model without symmetric assumption at the centerline. It is found that the flashback velocity is dominated by the upstream channel height; nevertheless, the blowoff velocity is determined by not only the downstream channel height but also the flow recirculation behind the sudden-expansion steps. As the expansion ratio is sufficiently large, the flame could exist within a substantially wider range of inlet flow velocity. In addition, four types of flame behaviors are found at the expansion ratio of 2: (I) steady convex flame, (II) steady concave flame, (III) simple oscillating flame, and (IV) complex oscillating flame. Above the flashback velocity, the convex flame exists steadily. With the increase in flow velocity, the flame becomes concave to the upstream and is stabilized by the wall-quenching effect of sudden-expansion steps. If the flow velocity is further increased, the flame becomes unstable and oscillates periodically (simple oscillating flame) due to the interaction of flame and the symmetric flow field in the sudden-expansion channel, while the occurrence of complex oscillating flame at high flow velocities is attributed to the asymmetric flow pattern. The frequency of oscillating flames decreases with the increase in flow velocity.

Effect of Flow Interference between Cylinders Subjected to a Cross Flow over a Cluster of Three Equally Spaced Cylinders

In this paper, flow over a cluster of three equally spaced circular cylinders was studied by numerical simulation based on the turbulence model k-kl-ω for two incidence angles β = 0° and 60°, at different Reynolds numbers, and flow interference pattern characteristics between cylinders, characteristics of force parameters, and Strouhal number of each cylinder with different spacing ratios ranging from 1.5 to 4 at Re 8 × 104, 2 × 105 and 2 × 106 were obtained. Analyzing the flow field around three cylinders, the following results have been obtained: (1) at incidence angle β = 0° and 60°, the wake was nearly symmetrical if S/D ≥ 2.0; (2) at β = 60°, S/D = 1.5, and Re = 2 × 105, an asymmetric periodic flow pattern occurred in the wake region which produced a significant effect on the surface mechanical parameters and Strouhal number, and this was observed for the first time. The periodic flow regime of the wake region also occurred at S/D = 1.35 and 1.5, without the same phenomenon at S/D = 1.7 and 2.0; this phenomenon is described for the first time in this paper; (3) the phenomenon of periodic flow regime in the wake region was intrinsic and related to Reynolds number and space ratio. In addition, the characteristics of force parameters of three cylinders were mainly affected by the interference between cylinders, at 1.5 < S/D < 4, which indicated that the drag coefficient of three cylinders reduces with different Reynolds numbers and increases with enlargement of the spacing ratio for upstream cylinders at incidence angle 0°. At incidence angle 60° and S/D = 1.5~4, the Strouhal number decreases with the enlargement of spacing ratio for the upstream cylinders, but the Strouhal number increases for the downstream cylinder, which is another prominent flow interference influence. The results indicated the effect of flow interference between cylinders subjected to a cross flow over a cluster of three equally spaced cylinders, considering the flow pattern, surface mechanical parameters and Strouhal number, which should be considered in the establishment of standard design codes in fields such as offshore wind turbine engineering for flow interference around groups of cylinders.

Natural Convection Fluid Flow and Heat Transfer in a Valley-Shaped Cavity

The phenomenon of natural convection is the subject of significant research interest due to its widespread occurrence in both natural and industrial contexts. This study focuses on investigating natural convection phenomena within triangular enclosures, specifically emphasizing a valley-shaped configuration. Our research comprehensively analyses unsteady, non-dimensional time-varying convection resulting from natural fluid flow within a valley-shaped cavity, where the inclined walls serve as hot surfaces and the top wall functions as a cold surface. We explore unsteady natural convection flows in this cavity, utilizing air as the operating fluid, considering a range of Rayleigh numbers from Ra = 100 to 108. Additionally, various non-dimensional times τ, spanning from 0 to 5000, are examined, with a fixed Prandtl number (Pr = 0.71) and aspect ratio (A = 0.5). Employing a two-dimensional framework for numerical analysis, our study focuses on identifying unstable flow mechanisms characterized by different non-dimensional times, including symmetric, asymmetric, and unsteady flow patterns. The numerical results reveal that natural convection flows remain steady in the symmetric state for Rayleigh values ranging from 100 to 7 × 103. Asymmetric flow occurs when the Ra surpasses 7 × 103. Under the asymmetric condition, flow arrives in an unsteady stage before stabilizing at the fully formed stage for 7 × 103 < Ra < 107. This study demonstrates that periodic unsteady flows shift into chaotic situations during the transitional stage before transferring to periodic behavior in the developed stage, but the chaotic flow remains predominant in the unsteady regime with larger Rayleigh numbers. Furthermore, we present an analysis of heat transfer within the cavity, discussing and quantifying its dependence on the Rayleigh number.

Hot gas impingement and radiation on neighboring surfaces from venting and combustion in a package of 18650 cells

A quasi-steady, CFD-based modeling approach is employed to investigate the heat loading within a small package of twenty-five 18650 Li-ion cells. The quasi-steady approach allows for computationally efficient simulations to capture the compressible and turbulent flow field through the safety vent structure and out into the space surrounding a failing cell. Combustion of vent gases leads to high heat loading on neighboring cells and nearby surfaces. Heat transfer mechanisms within the enclosure include convection from hot gases, radiation from the participating medium, and radiation exchange between surfaces. Simulations provide insight into the magnitude of each heat transfer mechanism, and the spatial distribution of heat flux on nearby cells and surfaces within the pack. The complex geometry of the safety vent geometry resulted in an asymmetric jet flow pattern, which induces highly localized impingement heat transfer on specific cells within the enclosure. Radiation from hot surfaces was more significant than radiation from hot gases and soot to neighboring cells. The quasi-steady simulations may be used in the future to develop reduced-order heat transfer models that include the effects of venting and combustion on propagating failure.

Computational analysis of cancer cell adhesion in curved vessels affected by wall shear stress for prediction of metastatic spreading.

Introduction: The dynamics of circulating tumor cells (CTCs) within blood vessels play a pivotal role in predicting metastatic spreading of cancer within the body. However, the limited understanding and method to quantitatively investigate the influence of vascular architecture on CTC dynamics hinders our ability to predict metastatic process effectively. To address this limitation, the present study was conducted to investigate the influence of blood vessel tortuosity on the behaviour of CTCs, focusing specifically on establishing methods and examining the role of shear stress in CTC-vessel wall interactions and its subsequent impact on metastasis. Methods: We computationally simulated CTC behaviour under various shear stress conditions induced by vessel tortuosity. Our computational model, based on the lattice Boltzmann method (LBM) and a coarse-grained spectrin-link membrane model, efficiently simulates blood plasma dynamics and CTC deformability. The model incorporates fluid-structure interactions and receptor-ligand interactions crucial for CTC adhesion using the immersed boundary method (IBM). Results: Our findings reveal that uniform shear stress in straight vessels leads to predictable CTC-vessel interactions, whereas in curved vessels, asymmetrical flow patterns and altered shear stress create distinct adhesion dynamics, potentially influencing CTC extravasation. Quantitative analysis shows a 25% decrease in the wall shear stress in low-shear regions and a 58.5% increase in the high-shear region. We observed high-shear regions in curved vessels to be potential sites for increased CTC adhesion and extravasation, facilitated by elevated endothelial expression of adhesion molecules. This phenomenon correlates with the increased number of adhesion bonds, which rises to approximately 40 in high-shear regions, compared to around 12 for straight vessels and approximately 5-6 in low-shear regions. The findings also indicate an optimal cellular stiffness necessary for successful CTC extravasation in curved vessels. Discussion: By the quantitative assessment of the risk of CTC extravasation as a function of vessel tortuosity, our study offers a novel tool for the prediction of metastasis risk to support the development of personalized therapeutic interventions based on individual vascular characteristics and tumor cell properties.

Unusual Tropical Cyclone Tracks under the Influence of Upper-Tropospheric Cold Low

Abstract Tropical cyclones (TCs) accompanied by an upper-tropospheric cold low (CL) can experience unusual tracks. Idealized simulations resembling observed scenarios are designed in this study to investigate the impacts of a CL on TC tracks. The sensitivity of the TC motion to its location relative to the CL is examined. The results show that a TC follows a counterclockwise semicircle track if initially located east of a CL, while a TC experiences a small southward-looping track, followed by a sudden northward turn if initially located west of a CL. A TC on the west side experiences opposing CL and β steering, while they act in the same direction when a TC is on the east side of CL. The steering flow analyses show that the steering vector is dominated by upper-level flow induced by the CL at an early stage. The influence of CL extends downward and contributes to the lower-tropospheric asymmetric flow pattern of TC. As these two systems approach, the TC divergent outflow erodes the CL. The CL circulation is deformed and eventually merged with the TC when they are close. Since the erosion of CL, the TC motion is primarily related to β gyres at a later stage. The sensitivity of TC motion to the CL depth is also examined. TCs located west of a CL experience a westward track if the CL is shallow. In contrast, TCs initially located east of a CL all take a smooth track irrespective of the CL depth, and the CL depth mainly influences the track curvature and the TC translation speed. Significance Statement The purpose of this study is to better understand how an upper-tropospheric cold low affects the motion of a nearby tropical cyclone. Our findings highlight distinct track patterns based on the relative positions of the tropical cyclone and the cold low. When the tropical cyclone is located on the east side of a cold low, a mutual rotation occurs, leading to a counterclockwise semicircle track of tropical cyclone. Conversely, if the tropical cyclone is located to the west side of a cold low, the cold low approaches and captures it, resulting in an abrupt northward turn when the cold low is eroded by the tropical cyclone. These insights improve the predictability of tropical cyclones in the vicinity of cold lows.

How wavelength affects hydrodynamic performance of two accelerating mirror-symmetric undulating hydrofoils

Fish schools are capable of simultaneous linear acceleration. To reveal the underlying hydrodynamic mechanism, we numerically investigate how Reynolds number Re=1000–2000, Strouhal number St=0.2–0.7, and wavelength λ=0.5–2 affect the mean net thrust and net propulsive efficiency of two side-by-side hydrofoils undulating in anti-phase. In total, 550 cases are simulated using immersed boundary method. The thrust increases significantly with the wavelength and the Strouhal number, yet only slightly with the Reynolds number. We apply a symbolic regression algorithm to formulate this relationship. Furthermore, we find that mirror-symmetric schooling can achieve a net thrust more than ten times that of a single swimmer, especially at low Reynolds numbers. The highest efficiency is obtained at St=0.5 and λ=1.2, where St is consistent with that observed in the linear-accelerating natural swimmers, e.g., Crevalle jack. Six distinct flow structures are identified. The highest thrust corresponds to an asymmetric flow pattern, whereas the highest efficiency occurs when the flow is symmetric with converging vortex streets.

Aeroacoustics and shear layer characteristics of confined cavities subject to low Mach number flow

Numerous engineering applications involve low Mach number flow in cavity aperture geometries, which can generate flow-excited acoustic oscillations and hence high amplitudes of noise and vibration. This is caused by the instability of the shear layer interacting with the acoustic modes of the system. In this study, we experimentally investigate ducted cylindrical cavities with aspect ratios (Depth/Diameter) of 0.5, 1, and 1.5 up to flow velocities of Mach 0.4. We examine the influence of the cavity confinement (Cavity Width/Duct Width) on the aeroacoustics response, as well as the downstream impingement behaviour of the shear layer. Rectangular and square cavities bearing similar geometric parameters are also investigated to compare the effect of the cavity shape on the shear layer dynamics and the aeroacoustics response. The results confirm resonance behaviour at frequencies well predicted by the theory, as well as Strouhal periodicities that agree with reported literature. However, cylindrical and square cavities with aspect ratio of 0.5 exhibit stronger dependence on the aspect ratio due to the interference of the recirculation region by the cavity floor, ultimately modifying the symmetry of the shear layer. This asymmetric flow pattern affects the velocity-dependent tones, generating much lower Strouhal numbers than the estimated values, and must be accounted for in equipment design. Moreover, Particle Image Velocimetry (PIV) measurements further illustrate the spatial characteristics of the shear layer dynamics for the various shaped cavities. The visualizations demonstrate enhanced flow modulation at higher acoustic pressure amplitudes, as well as reveal the flow asymmetry and the three-dimensional shear layer topology in cylindrical and square cavities.

Lack of genetic differentiation between two sympatric lacustrine morpho-species within the Astyanax (Characidae: Teleostei) genus, Mexico

We analyzed two morpho-species, Astyanax aeneus and Astyanax caballeroi, coexisting in Lake Catemaco, with ecological differences previously associated with different trophic niches. While A. aeneus is a widely distributed species, A. caballeroi is endemic to Lake Catemaco. Due to the contrasting morphology between these two sympatric species, they were originally assigned to different genera, but little is known about their genetic differentiation. We hypothesized that these two species, which present differentiation in morphology and in trophic niches, co-occur in concomitance with assortative mating and form distinct genetic clusters. We tested this prediction by typing a set of 12 microsatellites in 348 individuals of the two morpho-species, comparing their genetic structure patterns with that of an allopatric population of A. aeneus (i.e., the Maquinas population). Genetic structure analysis, assignment analyses, and estimation of gene flow between the sympatric morpho-species were carried out. Contrary to expectations, there is a lack of genetic differentiation between the A. aeneus and A. caballeroi morpho-species. However, there was a genetic differentiation between Lake Catemaco and Río Maquinas populations of A. aeneus. In addition, we found an asymmetric gene flow pattern, with a larger migration rate from A. aeneus to A. caballeroi than in the other direction. Finally, the allopatric population of A. aeneus showed lower levels of genetic diversity than those reported for both morpho-species in the lacustrine system. Consequently, our results support the notion that these morpho-species are either in an early phase of speciation or represent a single polymorphic species. This model provides relevant information to understanding the presence of polymorphisms under gene flow and their potential impact on the speciation process.

Permanent Magnet Pump for Aluminum Transport in a Linear Channel

Electromagnetic systems designed for liquid metal transportation offer a wide range of promising applications within the metallurgical industry. Among these systems, permanent magnet pumps stand out due to their remarkable advantages in processing liquid aluminum. These pumps enable the generation of a vigorous flow of liquid metal, all while maintaining a non-contact approach by bypassing the insulating walls. In this study, we investigate the flow of liquid metal in a rectangular cross-section channel created by a permanent magnet pump. To comprehensively analyze the flow characteristics and assess the technology's scalability, we employ order of magnitude evaluations alongside an experimental model. Ultrasound Doppler velocimetry is utilized to measure the velocity distribution, which reveals an intriguingly asymmetric flow pattern. Furthermore, additional measurements are conducted to determine the integral flow rate and pressure difference. Remarkably, the numerical simulations align closely with the experimental results, demonstrating good agreement in the p-Q curves. These findings provide substantial evidence supporting the remarkable potential of this technology in various applications, such as aluminum degassing, particle agglomerate dispersion, and efficient transportation.

Swirling flow and capillary diameter effect on the performance of an active dry powder inhalers

For patients with lung disease, dry powder inhalers (DPI) are profoundly beneficial. The current study introduces and develops a series of dry powder inhalers (DPIs). A capsule-based (size 0) active DPI was considered. The study aims to investigate whether swirling flow and outlet capillary diameter (dc_out) affect the percentage of emitted doses (ED) released from the capsule. Spiral vanes were added to the capillary inlet to produce a swirling flow. Computational fluid dynamics (CFD) was applied to simulate the problem. The results were compared with previous in vitro and numerical studies to validate the results. Based on the derived results, the small swirl parameter (SP) enhances the secondary flow and recirculation zone. It increases the central jet flow, which increases the ED value by about 5–20% compared to no-swirl flow. However, as the airflow rate increases, the recirculation zone enlarges, vorticities become dominant, and asymmetrical flow patterns emerge. Consequently, ED % drops significantly (more than 50%). As dc_out decreases, the vorticities around the outlet capillary become more potent, which is undesirable. Indeed, the emptying of the capsule does not happen ideally. The research provides a perspective on the device's design and DPI performance.

Influence of the adjustable EMBr on the asymmetric flow in a thin slab caster with a misaligned SEN

The thin slab casting (TSC) of steel is a type of the continuous casting (CC) with a narrow funnel-shaped mold, characterized by the rapid solidification and fast production rates. A highly turbulent flow impacts on a growing solid shell due to the constant feeding of the fresh hot melt. That strongly affects the solidification profiles and final quality of the TSC slabs. The presented work numerically investigates the solidification inside the TSC mold with the asymmetric flow pattern caused by the misalignment (tilting) of the submerged entry nozzle (SEN). These effects were considered with and without the applied electromagnetic brake (EMBr). The influence of the adjustable EMBr on the asymmetric flow and solidification profiles including turbulent and magnetohydrodynamic (MHD) effects were studied. During consistent series of simulations, the EMBr was varied between the magnetic poles and the time-averaged velocity and temperature fields were collected. The results showed that symmetric EMBr of a local type could partially improve the asymmetry. An optimal braking scenario was found for the casing speed of 5.5 m/min and maximum EMBr value of 180 mT. The solidification and MHD models including turbulence were developed using OpenFOAM®.

Investigation of periodic characteristics of perturbed flow over a slender body

The asymmetric flow over a slender body was particularly sensitive to the nose at a high angle of attack (AoA). Two patterns of separation occurred on the noses of the pointed-nosed slender body and blunt-nosed slender body as open- and close-type separation, respectively. The effects of the bluntness were investigated at high AoA (α = 50°) to clarify the evolution of the separated pattern from open-to close-type separation by the nose and by the periodic characteristics of perturbed flow. Wind tunnel experimental tests were conducted to investigate the periodic characteristics of asymmetric flow at a Reynolds number ReD = 1.54 × 105, based on incoming free-stream velocity (U∞) and the diameter (D) of the model. A particle was attached to the tip of the nose to induce the perturbed flow and attain a definite and predictable asymmetric flow in experimental tests. The pressure scanning and surface oil-flow visualization techniques were used to capture the pressure distributions and flow separations. The major findings were that axial flow increases with the increase of bluntness, resulting in open-type separation turning into close-type separation, and the perturbation moved from downstream to upstream of starting points of the separation line. The critical bluntness of separation pattern switching from open-type to close-type located between 1.5 and 3. Thus, the management of perturbation on asymmetric flow pattern switched from directly participating in separation to influencing separation through micro-flow. Therefore, the locations of perturbation and starting points of the separation line were closely related to asymmetric flow management by perturbation, then affecting the periodic characteristics of perturbed flow.

MHD Mixed Convection Flow of Hybrid Ferrofluid through Stagnation-Point over the Nonlinearly Moving Surface with Convective Boundary Condition, Viscous Dissipation, and Joule Heating Effects

This paper discusses a numerical study performed in analysing the performance regarding the magnetic effect on the mixed convection stagnation-point flow of hybrid ferrofluid, examining the influence of viscous dissipation, convective boundary condition as well as Joule heating across a nonlinearly moving surface. Additionally, the hybrid ferrofluid exhibits an asymmetric flow pattern due to the buoyancy force affecting the flow. Water H2O is employed as the base fluid collectively with the mixtures of nanoparticles containing magnetite Fe3O4 and cobalt ferrite CoFe2O4, forming a hybrid ferrofluid. The partial differential equation’s complexity is reduced by similarity transformation into a system of ordinary differential equations, which are then numerically solved by applying the MATLAB function bvp4c for a specific range of values regarding the governing parameters. Dual solutions were identified under both opposing and assisting flow conditions, and the stability analysis identified that the first solution was stable. Furthermore, it was also revealed that the addition of 1% CoFe2O4 in hybrid ferrofluid led to a higher skin friction coefficient between 3.35% and 7.18% for both assisting and opposing flow regions. Additionally, the growth of magnetic fields results in a reduced heat transfer rate between 8.75% to 10.65%, whilst the presence of the suction parameter expands the range of solutions, which then delays the boundary layer separation. With the Eckert number included, the heat transfer rate continuously declined between 7.27% to 10.24%. However, it increased by about 280.64% until 280.98% as the Biot number increased.

Gas kinematics around filamentary structures in the Orion B cloud

Context. Understanding the initial properties of star-forming material and how they affect the star formation process is key. From an observational point of view, the feedback from young high-mass stars on future star formation properties is still poorly constrained. Aims. In the framework of the IRAM 30m ORION-B large program, we obtained observations of the translucent (2 ≤ AV < 6 mag) and moderately dense gas (6 ≤ AV < 15 mag), which we used to analyze the kinematics over a field of 5 deg2 around the filamentary structures. Methods. We used the Regularized Optimization for Hyper-Spectral Analysis (ROHSA) algorithm to decompose and de-noise the C18O(1–0) and 13CO(1–0) signals by taking the spatial coherence of the emission into account. We produced gas column density and mean velocity maps to estimate the relative orientation of their spatial gradients. Results. We identified three cloud velocity layers at different systemic velocities and extracted the filaments in each velocity layer. The filaments are preferentially located in regions of low centroid velocity gradients. By comparing the relative orientation between the column density and velocity gradients of each layer from the ORION-B observations and synthetic observations from 3D kinematic toy models, we distinguish two types of behavior in the dynamics around filaments: (i) radial flows perpendicular to the filament axis that can be either inflows (increasing the filament mass) or outflows and (ii) longitudinal flows along the filament axis. The former case is seen in the Orion B data, while the latter is not identified. We have also identified asymmetrical flow patterns, usually associated with filaments located at the edge of an H II region. Conclusions. This is the first observational study to highlight feedback from H II regions on filament formation and, thus, on star formation in the Orion B cloud. This simple statistical method can be used for any molecular cloud to obtain coherent information on the kinematics.

Multilocus evidence provides insight into the demographic history and asymmetrical gene flow between Ostrinia furnacalis and Ostrinia nubilalis (Lepidoptera: Crambidae) in the Yili area, Xinjiang, China.

Tianshan Mountains provide a model for studying biological evolution and speciation. Here we assess the evolutionary history of Ostrinia furnacalis (ACB) and Ostrinia nubilalis (ECB), which are sympatric in the Yili River Valley in Xinjiang, China.Our study is based on the historical gene flow analyses of two species by using three mitochondrial DNA (mtDNA, COI, COII, Cytb) and four nuclear DNA (nuDNA, EF-1α, Wingless, RPS5, CAD) markers obtained from representatives of HC (Huocheng), YN (Yining), XY (Xinyuan), and MNS (Manasi).Our results reveal that there is an asymmetrical gene flow pattern between the four populations. The population migratory pathways between these different populations show inflow into HC and YN, outflow from XY, and that MNS maintained a flow balance. Bayesian divergence time dating based on the COI gene suggests that the genetic divergence between the two species in this area may have occurred in Holocene at 0.008 Mya. Neutrality tests (Tajima's D, Fu's F s), and mismatch distribution test results suggest that population expansion events may not have occurred in the recent past. The demographic history and gene flow pattern between ACB and ECB may follow the "mountain isolation" hypothesis. The ML and BI trees of the mtDNA haplotype dataset show that ECB haplotypes are grouped together in a distinct clade and are clearly separate from ACB haplotypes. However, the geographical pattern of haplotype distribution is less clear for both ACB and ECB, supporting that there has been frequent gene flow among the geographic populations in the Tianshan Mountains.These findings indicate that the Tianshan Mountains are less likely a barrier to gene flow of the two species.

Asymmetric Condensation Characteristics during Dropwise Condensation in the Presence of Non-condensable Gas: A Lattice Boltzmann Study.

In this work, the condensation characteristics of droplets considering the non-condensable gas with different interaction effects are numerically studied utilizing a multicomponent multiphase thermal lattice Boltzmann (LB) model, with a special focus on the asymmetric nature induced by the interaction effect. The results demonstrate that for isolated-like growth with negligible interactions, the condensation characteristics, that is, the concentration profile, the temperature distribution, and the flow pattern, are typically symmetric in nature. For the growth regime in a pattern, the droplet has to compete with its neighbors for catching vapor, which leads to an overlapping concentration profile (namely the interaction effect). The distribution of the condensation flux on the droplet surface is consequently modified, which contributes to the asymmetric flow pattern and temperature profile. The condensation characteristics for droplet growth in a pattern present an asymmetric nature. Significantly, the asymmetric condensation flux resulting from the interaction effect can induce droplet motion. The results further demonstrate that the interaction strongly depends on the droplet's spatial and size distribution, including two crucial parameters, namely the inter-distance and relative size of droplets. The asymmetric condensation characteristics are consequently dependent on the difference in the interaction intensities on both sides of the droplet. Finally, we demonstrate numerically and theoretically that the evolution of the droplet radius versus time can be suitably described by a power law; the corresponding exponent is kept at a constant of 0.50 for isolated-like growth and is strongly sensitive to the interaction effect for the growth in a pattern.

Beyond Janus Geometry: Characterization of Flow Fields around Nonspherical Photocatalytic Microswimmers.

Catalytic microswimmers that move by a phoretic mechanism in response to a self‐induced chemical gradient are often obtained by the design of spherical janus microparticles, which suffer from multi‐step fabrication and low yields. Approaches that circumvent laborious multi‐step fabrication include the exploitation of the possibility of nonuniform catalytic activity along the surface of irregular particle shapes, local excitation or intrinsic asymmetry. Unfortunately, the effects on the generation of motion remain poorly understood. In this work, single crystalline BiVO4 microswimmers are presented that rely on a strict inherent asymmetry of charge‐carrier distribution under illumination. The origin of the asymmetrical flow pattern is elucidated because of the high spatial resolution of measured flow fields around pinned BiVO4 colloids. As a result the flow from oxidative to reductive particle sides is confirmed. Distribution of oxidation and reduction reactions suggests a dominant self‐electrophoretic motion mechanism with a source quadrupole as the origin of the induced flows. It is shown that the symmetry of the flow fields is broken by self‐shadowing of the particles and synthetic surface defects that impact the photocatalytic activity of the microswimmers. The results demonstrate the complexity of symmetry breaking in nonspherical microswimmers and emphasize the role of self‐shadowing for photocatalytic microswimmers. The findings are leading the way toward understanding of propulsion mechanisms of phoretic colloids of various shapes.

Modeling Asymmetric Flow in the Thin‐Slab Casting Mold Under Electromagnetic Brake

Continuous casting (CC) is nowadays the world‐leading technology for steel production. The thin slab casting (TSC) is featured by a slab shape close to the final products and a high casting speed. The quality of the thin slabs strongly depends on the uniformity of the turbulent flow and the superheat distribution, defining the solid shell growth against a funnel‐shaped mold. In most studies, it is commonly assumed that the submerged entry nozzle (SEN) is properly arranged, and the melt inflow is symmetric. However, the misalignment or clogging of the nozzle can lead to an asymmetric flow pattern. Herein, the asymmetry is imposed via a partial SEN clogging: a) a local porous zone inside the nozzle reflects the presence of the clog material; b) the resistance of the clog is varied from low to high values. The solidification during TSC is modeled, including the effects of the turbulent flow. The variation of the flow pattern and the solidified shell thickness are studied for different permeability values of the SEN clogging. These effects are considered with and without the applied electromagnetic brake (EMBr) using an in‐house magnetohydrodynamics (MHD) and solidification solver developed within the open‐source package OpenFOAM.

Developing new quantitative CT image markers to predict prognosis of acute ischemic stroke patients.

Endovascular mechanical thrombectomy (EMT) is an effective method to treat acute ischemic stroke (AIS) patients due to large vessel occlusion (LVO). However, stratifying AIS patients who can and cannot benefit from EMT remains a clinical challenge. To develop a new quantitative image marker computed from pre-intervention computed tomography perfusion (CTP) images and evaluate its feasibility to predict clinical outcome among AIS patients undergoing EMT after diagnosis of LVO. A retrospective dataset of 31 AIS patients with pre-intervention CTP images is assembled. A computer-aided detection (CAD) scheme is developed to pre-process CTP images of different scanning series for each study case, perform image segmentation, quantify contrast-enhanced blood volumes in bilateral cerebral hemispheres, and compute features related to asymmetrical cerebral blood flow patterns based on the cumulative cerebral blood flow curves of two hemispheres. Next, image markers based on a single optimal feature and machine learning (ML) models fused with multi-features are developed and tested to classify AIS cases into two classes of good and poor prognosis based on the Modified Rankin Scale. Performance of image markers is evaluated using the area under the ROC curve (AUC) and accuracy computed from the confusion matrix. The ML model using the neuroimaging features computed from the slopes of the subtracted cumulative blood flow curves between two cerebral hemispheres yields classification performance of AUC = 0.878±0.077 with an overall accuracy of 90.3%. This study demonstrates feasibility of developing a new quantitative imaging method and marker to predict AIS patients' prognosis in the hyperacute stage, which can help clinicians optimally treat and manage AIS patients.