Ju-Suk Lee, MD, PhD, Cheol Hong Kim, MD, Jin-A. Jung, MD; Samsung Changwon hispital, Sungkyunkwan university, Changwon, South Korea, International St. Marry Hospital, Dong-A University College of Medicine, Busan, South Korea. RATIONALE: Asthma and atopic dermatitis are common chronic diseases and depression is an important comorbidity in allergic diseases. However, it is little known about the association between maternal depression and child allergic diseases. This study was performed to find the association between maternal depression and child allergic diseases. METHODS: Data were acquired from 2737 families who participated in the Fifth Korea National Health and Nutrition Examination Surveys (KNHANES), which was conducted from 2010 to 2012. RESULTS: The prevalence of childhood asthma was 5.3 % and childhood atopic dermatitis was 14.1%. The prevalence of maternal depression was 1.6 %. In univariate analysis, maternal depressions was associated with maternal smoking, lower education level, lower economic state, lower number of household members, maternal asthma,children’s asthma(p<0.05) but marital status, maternal employment status, maternal atopic dermatitis, children’s sex, children’s age, children’s atopic dermatitis, residence area were not associated with the presence of maternal depression. After adjustment, maternal depression was associated with lower house income, maternal asthma, children’s asthma.(p<0.05) CONCLUSIONS: The present study showed that maternal depression is associated with children’s asthma and not children’s atopic dermatitis. These results warrant future studies to explore the mechanisms responsible for the association between maternal depression and children’s asthma.