The present analysis discusses the effects of thermal-diffusion with thermal radiation, Joule heating and internal heat generation on peristaltic flow of a non-Newtonian fluid obeying Jeffery model. Heat and mass transfer are also taken into consideration, the flow is between two co-axial tubes under the effect of radially varying magnetic field. The inner tube is uniform and at rest, while the outer tube is flexible with sinusoidal wave traveling. The problem is modulated mathematically by a system of partial differential equations which describes the equations of momentum, heat, and mass transfer. These equations are solved analytically under the assumptions of long wave length and low-Reynolds number in non-dimensional form. The solutions are obtained as a functions of physical parameters of the problem. The radially varying magnetic field effect on the temperature and concentration distributions is analyzed and it is shown that the increase of Hartman number tends to reduce the temperature, while it increases the concentration.