Mathematical model of reaction systems contains experimental parameters such as reaction enthalpies, which may be inaccurate and, therefore, severely affect the computation as well as the implementation of feedback control laws. This paper aims to design an adaptive PI-like controller to regulate a chemical reaction system by means of the Lyapunov theory. More precisely, uncertain model parameters are updated online by solving a set of ordinary differential equations while the global asymptotic convergence of closed-loop system trajectories towards the desired equilibrium is ensured by using the proposed adaptive PI-like controller under the assumption of stability of isothermal conditions. The applicability of theoretical developments is illustrated with an irreversible first-order reaction system having multiple steady states and taking place in a non-isothermal continuous stirred tank reactor. Simulation results show that system trajectories initiated at different conditions are asymptotically stabilized at the desired values and the closed-loop system is robust against the uncertainty of heat exchange coefficient and dilution rate.
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