Assisted Injection Research Articles

Increasing trends in the use of the Precivia® intravitreal injection assist device across the UK.

Intravitreal anti-VEGF injections are the most frequently performed outpatient procedure in the UK, the need for which continues to rise. To meet this demand, injection assist devices such as Precivia® are increasingly adopted to aid in their prompt and safe delivery. We present data on the usage of Precivia® intravitreal injection assist device across two district general hospitals and its distribution across the UK over five years. A retrospective review was undertaken of all Precivia® assisted intravitreal injections delivered at Great Western Hospitals NHS Trust (GWH), and Gloucestershire and Cheltenham Hospitals NHS Trust (GCH) between 2015-2020. Data were also obtained from the Precivia® device UK distributor; Veni Vidi Medical. In GCH, 47,968 intravitreal injections were administered with Precivia®: 5947 in year 1; 7058 in year 2; 9893 in year 3; 11,503 in year 4 and 13,567 injections in year 5, observing a 128.13% increase in the use of Precivia® over the five-year-period. In GWH, 26,923 injections were administered with Precivia®: 4232 in year 1; 5117 in year 2; 5437 in year 3; 5878 in year 4 and 6259 in year 5, observing a 47.89% increase in Precivia® injections over a five-year study period. The number of Precivia® devices distributed across the UK similarly increased including 42,150 devices sold in 2015; 68,125 in 2016; 72,575 in 2017; 88,325 in 2018; 112,850 in 2019 and 115,125 in 2020 observing a 173.31% increase in five years. An increasing trend in the use of the Precivia® intravitreal injection assist device was observed across the UK.

Advanced pneumatic microgripper for versatile biomedical micromanipulation

Microgrippers offer better operational flexibility in biological micromanipulation. However, they face challenges in size miniaturization and environmental adaptability (especially in biological liquid environments). To overcome these challenges, a novel pneumatic microgripper is proposed with a thin-walled multi-airbag structure that directly drives the clamping jaws in motion, with a simple and compact overall construction. The microgripper has a maximum clamping range of 925 μm and can provide a clamping force exceeding 25 mN, capable of lifting loads over 300 times its weight. The microgripper is integrative and can be mass-produced with biocompatible resins in a single-step high-precision 3D printing process. The pneumatic microgripper is utilized to achieve the sorting and assisted injection of mouse oocytes (60–80 μm), assisted cutting of porcine oocytes (100–120 μm), and microscopic threading (10–15 μm) operation with two-finger cooperation. These demonstrations confirm it can operate fine manipulation of microscopic biological structures in air and liquid, and has good biocompatibility and cooperative operational ability. The developed pneumatic microgripper shows broad application prospects in biomedical applications such as microsurgery, micro biopsy, and assisted reproduction.

Stress analysis of a large diameter aspheric plastic lens in the variable temperature assisted injection molding process.

The technology known as precision injection molding (PIM) has shown great promise in the large-scale manufacturing of optical plastic lenses. The primary challenge with the PIM process is accurately predicting and reducing residual stress in optical plastic lenses. In this work, the finite element method (FEM) was used to analyze the residual stress distribution in plastic lenses. A three-dimensional model was created using COMSOL software to investigate how residual stress and temperature varied in optical plastic lenses during the packing and cooling stages. Based on the results, variable temperature assisted injection molding experiments were conducted. The results show that the average residual stress in the optical plastic lenses has decreased by 56%, while the minimum and maximum residual stress levels have decreased by 60% and 61%, respectively. Since this method does not require the extra heat treatment of the optical lenses, it offers considerable cost and efficiency benefits.

Experimental study on the effect of foam in preventing gas channeling in shale reservoir

Shale oil resources have enormous potential and broad development prospects in China. Especially with the rapid development of horizontal well volume fracturing technology, the production of shale oil has been greatly increased, and it has become an important position to increase oil and gas storage and production. However, due to the existence of artificial and natural fractures produced by fracturing, gas channeling will occur in the process of huff-n-puff gas injection, which will affect the production and lead to poor development effect. In this paper, foam is used as an anti-channeling agent in the process of huff-n-puff gas injection. The results of microfluidic experiments show that the production mode of foam in porous media is liquid membrane hysteresis and liquid membrane separation. In porous media, foam first blocks large channels such as fractures, and then enters the matrix. The oil recovery mechanism of foam assisted gas injection in porous media is to improve the sweep efficiency and oil displacement efficiency of gas. Compared with N2 huff-n-puff, the oil recovery of the first cycle of foam assisted N2 huff-n-puff increased by 4.50%, and the third cycle increased by 9.58%. It is proved that foam has good anti channeling effect in gas huff-n-puff injection process. The research results provide an effective method for efficient gas injection development of shale oil.

Strut-assisted injection of liquid fuel in a supersonic combustor

This paper investigates mixing and combustion of liquid fuel in a model scramjet combustor with strut-assisted injection adjacent to a cavity flame holder. Fuel/air mixing in a Mach 2.2 cross-flow and stagnation temperature of 1300 K was studied using filtered IR imaging. The insight gained by this method is discussed along with the method limitations. The impact of the strut assisted injection on the mixing of the liquid fuel was seen by the shorter vaporization distance, as the fuel vaporized upstream of the cavity, in contract to a liquid jet that expanded above most of the cavity when the strut was absent. Moreover, the fuel jet was seen to propagate laterally to the tip of the strut, which lead to lateral dispersion of the fuel up the strut height. The combustion experiments were conducted by piloting the cavity with ethylene and were imaged using CH* chemiluminescence. At stagnation temperature of 1300 K thermal choking and stable combustion occurred at equivalence ratio of 0.43, with the flame stabilizing at the strut wake, above the cavity. Intermittent thermal choking occurred at leaner condition. The flame stabilized on the cavity shear layer when the shock train moved downstream of the cavity and the flame stabilized at the strut wake when the shock train moved upstream. Thermal choking with the strut guided injection relative to a combustion only in the cavity without the strut is the result of the observed higher mixing efficiency, that enabled flame spreading into the supersonic flow and higher heat release. At a higher stagnation temperature of 1500 K the shock train moved downstream of the cavity, and the flame stabilized on the cavity shear layer. Finally, it is shown that the combustion efficiency could be further improved by injecting the fuel from the strut side walls.

La linfogammagrafía in vivo de los tumores del seno nasal identifica el ganglio retrofaríngeo y el nivel I como ganglios centinela predominantes

ObjectiveTo evaluate by in vivo lymphoscintigraphy and SPECT-CT imaging, the lymphatic drainage patterns of para-nasal sinus (PNS) tumours. To confirm or refute the belief of the retropharyngeal lymph node (RPLN) being the significant draining lymph node for such tumours. MethodsProspective cohort study conducted on previously untreated PNS tumours with no clinico-radiological evidence of lymph node metastasis. Lymphoscintigraphy undertaken by nasal endoscopic assisted peritumoral injection of 99mTc sulphur colloid. Injections were classified as anterior or posterior as per a vertical line along the maxillary sinus ostium. ResultsSeventeen patients were included. Lymphoscintigraphy successfully identified 17 sentinel nodes in 15 patients and was unsuccessful (lymphoscintigraphy failure) in 2 patients. Predominant sites of sentinel lymphatic drainage were noted to be the RPLN (n=8; 47%) and level I (n=7; 42%). Occasional drainage was identified at the peri-parotid node (n=1) and at level II (n=1). Contralateral drainage was noted in 2 patients (level I-1 and RPLN-1).Anterior injections drained predominantly to level I (6/8) and RPLN (2/8), while posterior injections drained predominantly to the RPLN (6/7). The relative risk of RPLN being identified as the sentinel node was significantly higher for posteriorly placed injections than for anteriorly placed injections (RR: 3.43; 95% CI: 1.0-11.8; P=.05). ConclusionThe RPLN is noted as a frequent draining node for sino-nasal tumours and merits routine attention in all sino-nasal tumours. The radio-colloid SPECT-CT technique described here offers an excellent in vivo technique to further explore and validate the lymphatic drainage pathways of these tumours.

Needlestick Injuries With Insulin Injections: Risk Factors, Concerns, and Implications of the Use of Safety Pen Needles in the Asia-Pacific Region.

Globally, health care workers (HCWs) are at a high risk of occupational exposure to needlestick injuries (NSIs). Needlestick injuries not only are associated with an increased risk of infections caused by bloodborne pathogens but are also a primary source of emotional distress and job burnout for HCWs and patients. Insulin injection-related NSIs are common among HCWs working in hospitals in the Asia-Pacific (APAC) region and impose a significant burden. Insulin pen needles have a high risk of transmitting infections (at both the patient-end and cartridge end of the sharp) after use. Recapping a needle after administering an insulin injection poses a major risk to HCWs. Currently, several safety-engineered needle devices (SENDs) are available with active or passive safety mechanisms. Passive insulin safety pen needles with dual-ended protection and automatic recapping capabilities have resulted in a significant drop in accidental punctures to HCWs while administering insulin to patients with diabetes. In this article, we have reviewed the burden and common causes of NSIs with insulin injections among HCWs in the APAC region. We have discussed current approaches to address the issues associated with NSIs and the benefits of introducing SENDs in health care settings, including long-term care facilities, nursing homes, and home care settings where patients may require assisted insulin injections. This review also summarizes key strategies/recommendations to prevent NSIs in HCWs and patients with diabetes in the APAC region.

In-vivo lymphoscintigraphy of sinonasal tumors identifies retropharyngeal node and level I as predominant sentinel nodes

ObjectiveTo evaluate by in- vivo lymphoscintigraphy and SPECT-CT imaging, the lymphatic drainage patterns of para-nasal sinus(PNS) tumors. To confirm or refute the belief of the retropharyngeal lymph node (RPLN) being the significant draining lymph node for such tumors. MethodsProspective cohort study conducted on previously untreated PNS tumors with no clinico-radiological evidence of lymph node metastasis. Lymphoscintigraphy undertaken by nasal endoscopic assisted peritumoral injection of 99mTc Sulfur colloid. Injections were classified as anterior or posterior as per a vertical line along the maxillary sinus ostium. Results17 patients were included. Lymphoscintigraphy successfully identified 17 sentinel nodes in 15 patients and was unsuccessful (lymphoscintigraphy failure) in 2 patients. Predominant sites of sentinel lymphatic drainage were noted to be the RPLN (n = 8; 47%), and Level I (n = 7; 42%). Occasional drainage was identified at the peri-parotid node(n = 1) and at Level II (n = 1). Contralateral drainage was noted in 2 patients (level I-1 and RPLN-1).Anterior injections drained predominantly to Level I (6/8) and RPLN (2/8), while posterior injections drained predominantly to the RPLN ( 6/7). The relative risk of RPLN being identified as the sentinel node was significantly higher for posteriorly placed injections than for anteriorly placed injections (RR- 3.43; 95% CI-1.0-11.8, p = 0.05). ConclusionThe RPLN is noted as a frequent draining node for sino-nasal tumours and merits routine attention in all sino-nasal tumors. The radio-colloid SPECT-CT technique described here offers an excellent in-vivo technique to further explore and validate the lymphatic drainage pathways of these tumours.

A comparative analysis of the effect of nanoparticles/surfactant assisted foam injection on the gas mobility control at different heterogeneities

Foam flooding is a popular method for increasing oil recovery in reservoirs with varying levels of heterogeneity. One common foam flooding technique is surfactant-assisted foam flooding (SF), which uses surfactants to create stable foam. However, SF is limited in high-pressure, high-temperature, and high-salinity reservoirs. To overcome these limitations, researchers have proposed a new approach called nanoparticles-assisted foam flooding (NAF), which involves adding nanoparticles to improve surfactant properties. While SF has been shown to improve sweep efficiency in heterogeneous reservoirs, the potential benefits of NAF are not fully understood. In this study, researchers investigated the performance of SF and NAF in controlling gas mobility in reservoirs with different levels of heterogeneity. They defined heterogeneity levels using sequential Gaussian simulation with varying standard deviation values. They also included a gas–water flooding (GW) scenario as a baseline. The results showed that SF effectively delayed breakthroughs and improved recovery factors in highly heterogeneous reservoirs. The researchers also compared normalized values of breakthrough time, breakthrough recovery factor, and recovery factor after 50 years for SF and NAF, which were normalized by corresponding GW results. Simulation results showed that SF and NAF could increase the normalized breakthrough time (SF: 10–17%, NAF: 12–42%), breakthrough recovery factor (SF: 11–20%, NAF: 16–53%), and recovery factor after 50 years (SF: 0–4%, NAF: 0–23%) compared to GW, depending on the heterogeneity level and NP concentration. The benefits of NAF compared to SF and GW were due to a significant decrease in gas mobility and saturation in the topmost layers, which facilitated the piston-wise movement of the front, resulting in higher sweep efficiency and recovery factor.

Women who use drugs: engagement in practices of harm reduction care

BackgroundHarm reduction services that employ or are operated by people who use drugs are an effective means of mitigating overdose risks and other drug-related harms. However, stereotypes portraying people who use criminalized drugs as incapable caregivers persist. This is especially true for women who use drugs, and to a greater extent racialized women, who are characterized as having diverged from traditional ideals of womanhood as a result of drug-user stigma and the intersections of gender- and class-based and racist stereotypes. In an effort to identify and understand how women who use drugs practise care through harm reduction, we explored the experiences of women accessing a low-threshold supervised consumption site exclusively for women (transgender and non-binary inclusive) in Vancouver, Canada.MethodsData were drawn from research conducted from May 2017 to June 2018 exploring women’s experiences accessing the supervised consumption site during an overdose crisis. Data included forty-five semistructured interviews with women recruited from the site, analysed thematically to explore practices of care through harm reduction.FindingsParticipants reported engaging in both formal and informal care. Acts of care included interventions that both aligned with and deviated from conventional understandings of care practices, including overdose reversal and education, overdose supervision/care, and assisted injection.ConclusionThe boundary between formal and informal harm reduction care is fluid. Women who use drugs engage in harm reduction across these borders with acts of care that align with or fill the gaps in current harm reduction services in order to meet the needs of drug-using communities, challenging negative stereotypes of women who use drugs. However, these caregiving practices can increase risks to care providers’ physical, mental, and emotional health and wellness. Increased financial, social, and institutional supports, including safer supply, assisted injection, and community resources, are needed to better support women as they continue to engage in harm reduction care.

Simulation study of a heat pump drying system using a solar assisted flash tank vapor injection cycle

Heat pumps are widely used in many fields due to their high efficiency and energy saving potential. However, the application of single-stage vapor-compression heat pump dryer is limited due to low drying temperature and the decreasing reliability for hightemperaturedrying. In order to apply heat pump to high temperature drying, a heat pump drying system using a solar assisted flash tank vapor injection cycle (HPDS-SFVIC) is presented. This system allows the solar collector to absorb solar energy at a lower temperature and achieves significant improvement of heating capacity and drying temperature. The effects of component configuration and various operating conditions on the drying system with open, bypass, and closed air circulation loop are evaluated, respectively. The results show that under a typical operating condition, the proposed cycle achieves great performance improvement of 21.8% and 75.8% in both the heating coefficient of performance (COPh) and heating capacity, compared with the conventional cycle. Utilization of solar energy is advantageous to provide higher air temperature for drying. With increased solar radiation intensity and collector area, heating capacity and drying temperature can be improved, while COPh remains constant as 5.0–5.2. When the drying system provides dry air at 65 °C stably, it saves 27.8%–41.7% of power consumption, and COPh is improved by 41.2%–62.1% on average.

Effect of Mn and Zn binary Co-substitution on structure and magnetic properties of cobalt ferrites

Mn-Zn binary co-substituted cobalt ferrite (Co1-x(MnZn)xFe2O4 (0 ≤ x ≤ 0.4)) was synthesized by conventionally compacting and magnetic field assisted injection molding. XRD and SEM analysis characterized the single-phase spinel structure, preferred 〈001〉 orientation, and uniform grain size. XPS analysis reveals the cation redistribution in the mixed spinel structure of co-substituted samples, which has a direct consequence on magnetic properties. The addition of Mn-Zn increases the saturation magnetization (Ms), while decreases magnetocrystalline anisotropy constant (K1), leading to a decrease of magnetostrictive saturation field (HS). For pressure samples, the maximum (dλ/dH)max is −0.15 ppm/Oe under 300 Oe applied field at x = 0.2. The samples with 〈001〉 fiber texture were prepared by magnetic field alignment of the semi-solid slurry to achieve higher magnetostrictive properties. The highest magnetostriction λS reaches −432 ppm, which is 200 % higher than pressed samples, and the corresponding maximum strain derivative (dλ/dH)max reaches −0.88 ppm/Oe at a lower magnetic field.

Experimental analysis of fluid‐assisted injection molding of pipe fittings with different angles by short‐shot method

AbstractBased on the self‐assisted injection experimental platform, experimental studies on gas‐assisted injection molding (GAIM), and water‐assisted injection molding (WAIM) of 2 curved pipe fittings by adopting short‐shot method were carried out. UDF model was constructed for numerical simulation analysis. The influence rules of auxiliary medium and bending angle on the terminal morphology, inner wall surface quality at bending angle, medial and lateral residual wall thickness, variation range, and residual wall thickness deviation rate of short‐shot fluid assisted injection molding (SSFAIM) bending samples were compared. Meanwhile, the influence mechanism was investigated. The following experimental findings were obtained. SSFAIM had secondary penetration, while water produced multiple penetrations. There are multiple vacuum shrinkage pores in the unpenetrated area at the end of the SSWAIM sample, as well as serious shrinkage depressions on the surface. The shape of the penetration front of water is arc‐shaped with many penetration holes. The shape of the penetration front of the gas at the end of the SSGAIM sample is “pointy.” Compared with the SSWAIM sample, the residual wall thickness of SSGAIM has a narrow distribution range when the bending angle is 0°. With the increase of the bending angle, the “foaming” phenomenon of the inner wall surface quality at the bending angle of the SSGAIM sample becomes less and less obvious. Moreover, the deviation of the inner and outer residual wall thickness of SSGAIM is more obvious than that of SSWAIM due to the increase of bending angle.

Gas Assisted Injection Molding of an Industrial Part: 3D Simulation Provides Virtual Molding Trials

Abstract Techniques developed for three-dimensional simulation of gas assisted injection molding of thermoplastics are here extended to a complex industrial application, a car door handle, providing uniquely detailed insights into the molding process. Handling of the three stages of the process – plastic filling, and primary and secondary gas penetration – is described in terms of the boundary and initial conditions applied. Predictions for plastic filling patterns are compared successfully with molding results, and provide detailed forewarning of potential problems due to weld surfaces and air-traps. Particular emphasis is placed on accurate modeling of secondary gas penetration, which is also validated against practical results. A further novel feature is the export of an STL model of the gas core, providing a CAD model of the finished molding for subsequent in-service analysis.

Redefining of ultrasound assisted injection pathway

Redefining of ultrasound assisted injection pathway

Shared injection experiences: Interpersonal involvement in injection drug practices among women

Background: Many women who inject drugs are aware of the associated risks, however social influences play a part in their behavioral decisions. Incorporation of others in drug use behaviors may be common practice among women who use drugs. The aim of this study was to gain an in-depth understanding of women’s injection drug use experiences with a focus on interpersonal involvement. Methods: Venue-based recruitment was conducted in collaboration with a harm reduction program. A group of 30 women, ages 18 and older, who reported injecting drugs within the past 30 days took part in a demographic survey and semi-structured interview to gain an understanding of their injection practices. In vivo coding and thematic analysis were conducted. Results: Three main themes that relate to incorporating others into injection drug behaviors surfaced, including: (1) injection practices described as we and not I, (2) partnered purchase and drug preparation, and (3) assisted injection. This group of women most often incorporated sexual and/or romantic partners (same and other-gender), friends, or family members into their injection drug use behaviors. Some women described a lack of ability to inject themselves and require assistance every time they use. Women also reported helping other women during drug use behaviors. Conclusions: Our primary themes indicate that a variety of relationship partners are important conceptual links in theoretical frameworks explaining drug use behaviors among women. Findings suggest same gender assistance during drug use behaviors, including injection, that may reduce harm. The interpersonal nature of injection drug use among women may indicate the expansion of treatment options designed for couples or other relationship partners, such as family, together.

Factors associated with injury and blood-borne infection risk when providing assisted injection among people who inject drugs.

Prior research has associated assisted injection with risk behaviors, but other risks such as injury, missed veins, and incidental exposures to blood-borne infections during an injection episode have not been assessed. In the following, we present the frequency of these other risks and determine factors associated with missing a vein and incidental blood exposure among people who inject drugs (PWID). We conducted a cross-sectional analysis of data from PWID who were recruited using targeted sampling in Los Angeles and San Francisco, California, during 2016 and 2017. The analytic sample consist of 336 participants who reported providing injection assistance in the last 6 months. Multivariate logistic regression models were developed for reporting the following risks: missing a vein; getting the recipient's blood on the injection provider; and getting blood on clothes or surfaces. In the last 6 months, the most common negative consequences were getting blood on clothes or surfaces (40%), getting the recipient's blood on the injection provider (23%), and missing a vein (17%). In multivariate logistic regression analysis, missing the vein was significantly associated with higher odds of assisting a leg injection while getting the injection recipient's blood on the provider or getting blood on clothes or nearby surfaces was associated with higher odds of assisting a groin injection injecting in the groin. Providing injection assistance can result in incidental blood exposures and injury, particularly when injecting in sensitive locations on the body. Harm reduction interventions to reduce risks associated with this practice are essential to improving the well-being of PWID.

Assisted injection provider practices and motivations in Los Angeles and San Francisco California 2016–18

BackgroundAssisted injection is a high-risk and common practice among people who inject drugs (PWID) and occurs for diverse reasons according to qualitative research. To develop interventions for reducing assisted injection risks, it is important to understand the practices of PWID who provide injection assistance, including their motivations for providing assistance. MethodsUsing follow-up data from an efficacy trial among PWID recruited in Los Angeles and San Francisco, CA (n=601), we present descriptive statistics on motivations for providing injection assistance and use multivariable logistic regression modelling to examine factors associated with these motivations. ResultsPWID provided injection assistance most commonly to friends and acquaintances. A quarter provided assistance on a daily basis. The most common motivations for providing assistance were skill and injury prevention. PWID also provided assistance to stop pestering and for compensation in money or drugs. In separate models examining factors associated with the five main motivations, we found injury prevention to be associated with skill injecting others, neck injection, methamphetamine use, and recycling income. Pestering was associated with injury prevention, neck and hand injection, speedball use, and syringe selling. Skill was associated with injury prevention, neck and hand injection, being physically assaulted, and age. Providing assistance for money was associated with providing assistance for food or drugs, armpit injections, being female, and providing assistance more frequently. Providing assistance for drugs was associated with compensation in food or money, goofball injection, selling drugs, and panhandling. ConclusionProviding injection assistance is associated with injection needs of recipients and drug scene participation. We urgently need new interventions for reducing assisted injection risks. Since injection providers report being motivated by skill and to prevent injury, interventions such as training in safer injection techniques are likely to be met with enthusiasm.

Rules and Eligibility Criteria for Supervised Consumption Services Feasibility Studies – A Scoping Review

IntroductionSupervised consumption services (SCS) reduce HIV risks and overdose for people who use drugs (PWUD) and are known to have wide-ranging public health benefits. Feasibility studies are often conducted as part of program/implementation development. We conducted a scoping review of SCS feasibility/pre-implementation studies to answer: what is known about stakeholders’ opinions of SCS rules and eligibility criteria? MethodsUsing the PRISMA-ScR guidelines, we searched Medline, PsychINFO, Embase, CINAHL, and SCOPUS databases for: (a) empirical research, (b) reported in English, (c) focused on SCS, (d) pre-implementation feasibility studies (research conducted prior to implementation of SCS in a given context), (e) examining SCS operational rules and eligibility criteria. Abstracts were reviewed to verify appropriateness; full articles/reports were retrieved; data were extracted and charted. ResultsOf the 1,268 data sources identified/reviewed, 19 sources, were included. Manuscripts showed the following criteria that might be considered when determining who can and cannot use SCS: age, pregnancy status, and opioid substitution treatment status. To govern behaviours at SCS, manuscripts focused on: acceptable modes of drug consumption, assisted injections, sharing drugs on-site, pill injecting, and mandatory hand washing, etc. Stakeholders generally agreed that; eligibility restrictions and site rules should be minimal to establish low-barrier services. SCS are often forced to contend with the tension between adhering to a medical or public health model and creating low-barrier services. SCS rules are at the center of this intersection because rules and eligibility criteria implemented to mirror other health services may not align with the needs of PWUD. ConclusionGiven the public health significance of SCS, establishing best practices for service delivery is critical for increasing access and addressing implementation issues. Future research should examine other operational elements of SCS, such as design elements, staffing models, and ancillary services. Additional research should also focus on supervised smoking services.

Computer modeling of the gas assisted injection molding process - computer simulations vs. practice

Modern computer programs for simulation of polymer processing allow to conduct numerical calculations on the movement of the injected material, not only in the classical injection molding process. It is possible to simulate non-standard injection methods, e.g. gas assisted injection process. The paper presents the results of computer simulations and real gas-assisted injection. These results were compared and the compliance of numerical calculations with the results of practical tests was assessed. It has been shown that advanced algorithms of computer simulation programs enable modeling of phenomena specific to the injection method under consideration. The ability to conduct simulations of polymer processing processes (including gas-assisted injection) allows to shorten the time of implementation of molds for production, eliminate construction errors and expanding knowledge about the course of the actual process. The work focuses on the gas-assisted injection process by filling the forming cavity entirely in the melt filling phase. Particular attention was paid to the gas channel formation process and the parameters that determine its shape and dimensions.