In this small series of cases, Nos. 2, 3, 4 and 5 showed definite clinical and mental improvement—sufficiently so to admit of their discharge from hospital. From both the mental and physical points of view the results are excellent, although in each case deviations from the normal are still to be found on examination of the nervous system. In Case 3, in whom the disease was in a very acute form, a degree of facility remains, but this should not prevent him taking his place in the outside world again. Cases 2, 4 and 5 show the best results. They are very well mentally and physically, all good workers, and quite capable of resuming a normal life. From a serological point of view, the changes in blood and cerebro-spinal fluid have not shown parallel improvement to that noted in the clinical pictures, although in 5 cases there has been some slight amelioration. It is possible that without further treatment there may be a more convincing serological result in the course of a few months. For example, Case 1, some months after cessation of treatment, has shown considerable alteration in blood and cerebro-spinal fluid, not noted shortly after treatment was stopped. In addition there has been slight but progressive mental improvement. Considering the short period these patients have been under care and treatment, it is impossible to say how long they will remain well. With the assistance of the relatives and of the patients themselves it is hoped to follow their further progress.