The discipline «Histology, cytology, embryology» is part of the basic disciplines and, therefore, is important not only from the point of view of obtaining specific theoretical and practical knowledge, but also from the point of formation of skills for independent work, and in the future– motivation for constant self-education. It is advisable to teach students not only the content of the subject, but also mental operations. One of the most important areas is the formation among medical students of the ability to systematize the results, make generalizations and evaluate their reliability and application limits, plan and conduct research. The purpose of this practical lesson it`s to fix in memory the technique of microscopic examination of a histological preparation, develop an idea of the nature and content of the main stages in preparation of a fixed and stained histological slides, get an idea of the «basophilia» and «oxyphilia» structures in the histological preparation. The learning process is impossible without remembering the basic facts, patterns, postulates, etc. The effectiveness of memorizing educational material depends on how logically it is connected with the knowledge that medical students already have and can be well understood by them. In this case, the teacher must seek arbitrary memorization. He indicates the goal of assimilation of certain information, identifies the main and secondary, stimulates the necessary motivation of the cognition process on the part of students. The conditions for successful memorization are: comprehension of educational material, mental activity and independence in work, constant use of the memorized, understanding of its significance, its reproduction in the process of repetition, and practical application of the studied. Correct systematization of students' learning activities allows the teacher to evaluate the knowledge, skills and abilities they receive, provide the necessary assistance on time and achieve the learning objectives. All this together creates favorable conditions for the development of cognitive abilities of students and the activation of their independent work in practical classes in histology. The learning process is impossible without memorizing the basic facts, schemes, postulates, etc. The effectiveness of memorizing educational material depends on how logically it is related to the knowledge already available to medical students and, perhaps, well understood by them. In this case, the teacher must seek arbitrary memorization. It indicates the purpose of assimilation of certain information, highlights the main and secondary, stimulates the necessary motivation of the learning process by students. Conditions for successful memorization are: comprehension of educational material, mental activity and independence in work, constant use of memorized, understanding of its significance, its reproduction in the process of repetition and practical application of the studied. Properly set systematization of students' learning activities allows the teacher to assess the knowledge, skills, abilities, to provide the necessary assistance in a timely manner and to achieve the goals of learning. All this together creates favorable conditions for the development of cognitive abilities of students and the activation of their independent work in practical classes in histology.