Thalassemia is a hereditary condition that affects the formation of globin chains. Beta thalassemia is characterized by either a total loss of manufacture globin (β-thalassemia major) or a partial loss of globin manufacture (β-thalassemia minor). This type of inherited anemias is found in Mediterranean and Southeast Asian communities. Objective: Assessment of parents' knowledge regarding home health care management related to children with β-Thalassemia Major. Methodology: A descriptive study design was carried out at Thalassemia Center in Al-Najaf City during the periods 25 ͭͪ February 2021 to 15 ͭͪ March 2022. Non-probability (purposive) sample of (35) parents were selected from thalassemia center (22 mothers and 13 fathers). Results: The finding shows that 77.1% of parents are resident in urban. The monthly income, over than half (54.3%) of parents consider their income to be barely sufficient. The sources of information about disease among parents; (88.6%) of parents are getting information from medical team. The parents are demonstrating poor knowledge level in most domains about home health care management of child with beta thalassemia major. Conclusion: The current study shows that there is a significant inadequacy in the parents' knowledge of the child with beta thalassemia major. Recommendation: Providing educational guidelines, posters, pamphlets and manuals about thalassemia and should be available at each parents in wards and encourage parents to get use from them.
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