Successful Aspiration Research Articles

Using E-Textiles to Challenge Gender Perceptions in STEM, Design and Career Aspirations of Secondary School Students

STEM subjects in the secondary school curriculum are largely the domain of boys, and the creative arts subjects are predominantly the territory of girls. This disparity permeates into higher education and leads to a gender imbalance in the workforce. This paper investigates issues of gender bias in the secondary school curriculum and explores student perceptions and self-efficacy for future academic success. Using the medium of electronic textiles (e-textiles) the research considers if multidisciplinary and co-design approaches to teaching could create a more gender-equitable environment, bring about a mindset shift in students’ gender perceptions, and alter their perspectives for future university choices. A mixed-gender group of 32 secondary school students from different subject disciplines across science, technology and art and design took part in a year-long study. They were given opportunities to work on a co-design project which sought to break down barriers between subject disciplines and challenge stereotypical perceptions of the “type” and gender of student in each discipline. Students were introduced to an e-textiles project called “ElectroTex” which sought to challenge the current hidden-gendered curriculum. It drew upon curriculum topics from physics, computing, technology and art and design. The research was underpinned by overlapping frameworks of Social Cognitive Theory and Value Expectancy Theory. A mixed methodology approach comprising Action Research and Co-design was sandwiched between pre- and post-project questionnaires which determined how students’ perceptions had altered as a result of the project. The experiential learning demonstrated that students were able to connect science with design and harness the value of their collaborative knowledge by applying it to real life situations. The outcomes show that a multidisciplinary approach to learning can re-frame students’ perspectives on gender in the curriculum, empower them to consider design and science in mutually beneficial contexts, and raise their aspirations for future success.

Beyond money, power, and masculinity: Toward an analytical perspective on recruitment to Mexican drug trafficking organizations

Mexican drug trafficking organizations have experienced rapid attrition resulting in a continual need for personnel since 2006. However, the process by which these criminal organizations absorb new members remains obscure. In this article, we report on the social context of recruitment and motivational pathways into Mexican drug trafficking organizations through in-depth interviews with current and former cartel members ( N = 79). We find that recruits are motivated by aspirations of financial success and notions of masculinity, but also influenced by attachment to social groups and jointly shared experiences that we term a collective trajectory. We argue that individual decisions to join criminal organizations are viewed in collective terms, or being connected with members of their immediate social group. We conclude with the applications of challenges of collective trajectory for sociological criminology.

Delving the Level of Instructional Support among Basic Education Unit Teachers

It is essential to develop new instructional models that are in keeping with the subject matter being considered and centered on the learning goals outlined in the curriculum. The purpose of this study was to investigate junior high school student’s performance in geometry as well as the degree of instructional support provided by their teachers at secondary schools located within the Pampanga Division. For this piece of research, the researcher chose to apply the quantitative research design. A descriptive- correlational methodology was utilized for the purpose of this investigation. According to the findings, instructors have a strong connection and a positive rapport with the groups of pupils that they are responsible for teaching. In addition, it was discovered that school administrators give teachers in public elementary schools training and innovative tools so that the instructors can improve their delivery of the national curriculum while also fostering dynamic and fruitful classroom debates and activities. The results of the study showed that most of the students who participated in the survey did not meet the criteria established for their performance in geometry. The conclusion that may be drawn from this is that kids have a bad performance in geometry, as would be attested by their assessment. In conclusion, the results suggested that there is no significant association between the level of instructional support offered by the teacher- respondents and the level of achievement attained by the student-respondents on the topic of Geometry. It provides the idea that there is no connection between the level of instructional support offered by the teacher-respondents and the performance of the student-respondents in geometry and vice versa. It was recommended that Action plans and enhancement programs/ projects may need to be addressed to educate and be contributed to the school’s achievements, no matter what kinds of success aspirations the school is pursuing.

TCTAP C-042 A Case of Successful Thrombus Aspiration in a Patient With Intermediate-High Risk Pulmonary Embolism

TCTAP C-042 A Case of Successful Thrombus Aspiration in a Patient With Intermediate-High Risk Pulmonary Embolism

Primary thrombosis of the anterior descending in a patient with antiphospholipid antibody syndrome

Antiphospholipid antibody syndrome is a heterogeneous clinical and biochemical entity. We present the case of a young male with history of venous thromboembolism. This time he presents because of chest ischemic pain associated with ST segment elevation. He was taken to the cath lab to perform a primary percutaneous coronary intervention and a total occlusion of the left anterior descending artery was noted. Successful thrombus aspiration was performed. No stent was deployed. He was taken to the cath lab for a second look angiography and no atherosclerotic lesions were observed, which was confirmed by intravascular ultrasound.

Successful Air Bubble Aspiration in the Left Atrium Using Three-Dimensional Transesophageal Echocardiography.

Successful Air Bubble Aspiration in the Left Atrium Using Three-Dimensional Transesophageal Echocardiography.

Anatomic, physiologic, and proteomic consequences of repeated microneedle-mediated perforations of the round window membrane

BackgroundWe have developed 3D-printed microneedle technology for diagnostic aspiration of perilymph and intracochlear delivery of therapeutic agents. Single microneedle-mediated round window membrane (RWM) perforation does not cause hearing loss, heals within 48–72 h, and yields sufficient perilymph for proteomic analysis. In this study, we investigate the anatomic, physiologic, and proteomic consequences of repeated microneedle-mediated perforations of the same RWM at different timepoints. Methods100-μm-diameter hollow microneedles were fabricated using two-photon polymerization (2PP) lithography. The tympanic bullae of Hartley guinea pigs (n = 8) were opened with adequate exposure of the RWM. Distortion product otoacoustic emissions (DPOAE) and compound action potential (CAP) were recorded to assess hearing. The hollow microneedle was introduced into the bulla and the RWM was perforated; 1 μL of perilymph was aspirated from the cochlea over the course of 45 s. 72 h later, the above procedure was repeated with aspiration of an additional 1 μL of perilymph. 72 h after the second perforation, RWMs were harvested for confocal imaging. Perilymph proteomic analysis was completed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). ResultsTwo perforations and aspirations were performed in 8 guinea pigs. In six, CAP, DPOAE, and proteomic analysis were obtained; in one, only CAP and DPOAE results were obtained; and in one, only proteomics results were obtained. Hearing tests demonstrated mild hearing loss at 1–4 kHz and 28 kHz, most consistent with conductive hearing loss. Confocal microscopy demonstrated complete healing of all perforations with full reconstitution of the RWM. Perilymph proteomic analysis identified 1855 proteins across 14 samples. The inner ear protein cochlin was observed in all samples, indicating successful aspiration of perilymph. Non-adjusted paired t-tests with p < 0.01 revealed significant changes in 13 of 1855 identified proteins (0.7%) between the first and second aspirations. ConclusionsWe demonstrate that repeated microneedle perforation of the RWM is feasible, allows for complete healing of the RWM, and minimally changes the proteomic expression profile. Thus, microneedle-mediated repeated aspirations in a single animal can be used to monitor the response to inner ear treatments over time.

Successful aspiration of an iatrogenic clot in transit secondary to a failed mechanical thrombectomy in pulmonary embolism.

A 68-year-old female presented with an intermediate-high-risk bilateral pulmonary embolism (PE) (Panel A) with a severely dilated right ventricle (Panel B). Ultrasound of both femoral veins was normal. Thrombolysis was not performed owing to recent history of gastrointestinal bleeding. The PE team decided to perform a percutaneous mechanical thrombectomy (MT) using the FlowTriever (FT) system (Inari Medical, Irvine, CA, USA). After the first procedure, a large thrombus was obtained from the right pulmonary artery (Panels C–E and Supplementary Video 1); however, we failed to extract any thrombus from the left pulmonary artery (LPA) with both the 24 and 16 Fr catheters, due to tortuosity and poor wire support, with non-sustained ventricular tachycardia. A transthoracic echocardiogram (TTE) and a subsequent transoesophageal echocardiography revealed the presence of a massive clot attached to the tricuspid valve, with severe tricuspid regurgitation (Panels F and G and Supplementary Video 2) that was not present in baseline TTE. Considering it was an iatrogenic event due to a ‘lollipop thrombus’, and the risk of re-embolization, a further MT procedure was performed, with TTE guidance, with the successful retrieval of the clot in transit (Panels H and I), and the remaining LPA thrombi (Panels J–L, Supplementary Video 3).

Management of Primary Spontaneous Pneumothorax in Children: A Single Institution Protocol Analysis

BackgroundThe Midwest Pediatric Surgery Consortium (MWPSC) suggested a simple aspiration of primary spontaneous pneumothorax (PSP) protocol, failing which, Video-Assisted Thoracoscopic Surgery (VATS) should be considered. We describe our outcomes using this suggested protocol. MethodsA single institution retrospective analysis was conducted on patients between 12 and 18 years who were diagnosed with PSP from 2016 to 2021. Initial management involved aspiration alone with a ≤12 F percutaneous thoracostomy tube followed by clamping of the tube and chest radiograph at 6 h. Success was defined as ≤2 cm distance between chest wall and lung at the apex and no air leak when the clamp was released. VATS followed if aspiration failed. ResultsFifty-nine patients were included. Median age was 16.8 years (IQR 15.9, 17.3). Aspiration was successful in 33% (20), while 66% (39) required VATS. The median LOS with successful aspiration was 20.4 h (IQR 16.8, 34.8), while median LOS after VATS was 3.1 days (IQR 2.6, 4). In comparison, in the MWPSC study, the mean LOS for those managed with a chest tube after failed aspiration was 6.0 days (±5.5). Recurrence after successful aspiration was 45% (n = 9), while recurrence after VATS was 25% (n = 10). Median time to recurrence after successful aspiration was sooner than that of the VATS group [16.6 days (IQR 5.4, 19.2) vs. 389.5 days (IQR 94.1, 907.0) p = 0.01]. ConclusionSimple aspiration is safe and effective initial management for children with PSP, although most will require VATS. However, early VATS reduces length of stay and morbidity. Level of evidenceIV. Retrospective study.

Successful Aspiration of a Cervical Synovial Cyst Under Fluoroscopy

Successful Aspiration of a Cervical Synovial Cyst Under Fluoroscopy

Just-in-time Training with Remote Guidance for Ultrasound-Guided Percutaneous Intervention

BACKGROUND: Management of surgical emergencies in spaceflight will pose a challenge as the era of exploration class missions dawns, requiring increased crew autonomy at a time when training and supplies will be limited. Ultrasound-guided percutaneous intervention would allow for the management of a variety of pathologies with largely shared equipment and training. This proof-of-concept work attempts to determine the feasibility of "just-in-time" remote teaching and guidance of a sample procedure of this type.METHODS: Subjects naïve to ultrasound-guided intervention were instructed via a short video regarding the technique for placement of a percutaneous drain into a simulated abscess within a gel phantom. Subjects were then guided through the performance of the procedure via two-way audiovisual communication with an experienced remote assistant. Technical success was determined by the successful aspiration or expression of fluid from the simulated abscess following drain placement. This was then performed by and compared with staff experienced with such procedures. Time to completion and number of needle redirections required were also measured.RESULTS: All 29 subjects naïve to interventional work and the 4 experienced control subjects achieved technical success. There was a statistically significant difference in the time to completion between the two groups, with the experienced subjects averaging 2 min to completion and the inexperienced 5.8 min. There was no statistically significant difference in the number of redirections.DISCUSSION: This proof-of-concept work demonstrates high rates of technical success of percutaneous ultrasound-guided intervention in previously inexperienced personnel when provided with brief just-in-time training and live two-way audiovisual guidance.Lerner DJ, Pohlen MS, Apland RC, Parivash SN. Just-in-time training with remote guidance for ultrasound-guided percutaneous intervention. Aerosp Med Hum Perform. 2022; 93(12):882-886.

Factors Impacting the Yield of Image-Guided Biopsy in Native Vertebral Osteomyelitis: A 10-Year Retrospective Study.

Image-guided biopsies in patients with suspected native vertebral osteomyelitis (NVO) are recommended to establish the microbiological diagnosis and guide antibiotic therapy. Despite recent advances, the microbiological yield of this procedure remains between 48% and 52%. A better understanding of factors associated with this low yield may lead to improved microbiological diagnosis. We retrospectively identified patients with suspected NVO undergoing image-guided biopsies from January 2011 to June 2021 at our institution. Two hundred nine patients undergoing 248 percutaneous biopsies were included. Demographic data, biopsy and microbiologic techniques, clinical characteristics, and antibiotic use were collected. Multivariable logistic regression analysis was conducted to determine factors associated with microbiological yield. A total of 110 of 209 (52.6%) initial image-guided biopsies revealed positive microbiological results. This number increased to 121 of 209 (57.9%) when repeat image-guided biopsies were included. In multivariable analysis, aspiration of fluid was associated with a 3-fold increased odds of yielding a positive result (odds ratio [OR], 3.13; 95% confidence interval [CI], 1.39-7.04; P = .006), whereas prior antibiotic use was associated with a 3-fold decreased yield (OR, 0.32; 95% CI, .16-.65; P = .002). A univariate subgroup analysis revealed a significant association between the length of the antibiotic-free period and microbiological yield, with the lowest rates of pathogen detection at 0-3 days and higher rates as duration increased (P = .017). Prior antibiotic use in patients with suspected NVO was associated with a decrease in the microbiological yield of image-guided biopsies. An antibiotic-free period of at least 4 days is suggested to maximize yield. Successful fluid aspiration during the procedure also increases microbiological yield.

Hip aspiration: A comparison of ultrasound and fluoroscopic guidance

IntroductionHip aspirations are commonly performed for diagnostic purposes using either fluoroscopic or ultrasound guidance. The superiority of one type of image guidance over another for aspiration of a native or replaced hip remains a matter of debate. The questions to be evaluated in this study include 1) to determine if hip aspiration using fluoroscopy or ultrasound guidance more often obtains fluid from native and post-arthroplasty hip joints, and 2) to identify patient-related factors associated with the ability to obtain fluid. Material and methodsA retrospective analysis of all hip aspirations (433) performed at a single institution was undertaken, with the primary outcome variable being successful attainment of joint fluid. Age, body mass index (BMI), sex, presence of a trainee, presence of an arthroplasty at the time of aspiration on the affected side, amount of fluid collected, and type of image guidance were used as independent variables in regression models. Results1) The likelihood of obtaining fluid was approximately 2.1 times greater with ultrasound guidance than fluoroscopy guidance (95% CI = 1.382, 3.117; p < 0.001). 2) Ultrasound guidance and lower BMI were independently associated with a significantly higher likelihood of obtaining fluid. Additionally, one unit decrease in BMI was associated with about a 3% increase in the odds of obtaining fluid (95% CI = 0.950, 0.998; p = 0.033). ConclusionThis study demonstrates that the use of ultrasound guidance for hip joint aspiration, when compared to fluoroscopic guidance, is more likely to result in a successful aspiration and the acquisition of a greater volume of fluid. Therefore, ultrasound guidance is the preferred method for hip aspiration in both native and replaced hips.

Intergenerational aspirations for educational and employment success of refugee youth

ABSTRACT While studies on refugee-background students in school contexts have been prolific, research of this population in higher education or post-tertiary education is still emergent. The paper attends to this gap by drawing on the narratives of five refugee-background young adults who are undertaking Australian higher education or have completed university studies. An interpretive analysis of their life-story interviews is drawn from Appadurai’s concept of ‘voice’ as a tool to understand the intergenerational nature of ‘aspiration’. We illustrate the heterogeneous ways their resourcefulness is activated in pursuit of their aspirations, and the enabling role parental aspirations play in realising their pathways. It offers new insights on the enabling role refugee parents play to support their children’s pathway into higher education. It also highlights the significance of individual refugee youth agency in navigating on-going challenges to attain their personal aspirations through education. We argue that the concept of inclusive education should contain a strength-based view of refugee students that positions them as aspirational individuals who are actively engaging in complex forms of negotiation, adaptability and resistance. Further research into inclusive education for increased social inclusion, incorporating the intergenerational aspirations of both refugee youth and their parents is clearly warranted.

Vacuum-Implemented Removal of Lead Vegetations in Cardiac Device-Related Infective Endocarditis.

When approaching infected lead removal in cardiac device-related infective endocarditis (CDRIE), a surgical consideration for large (>20 mm) vegetations is recommended. We report our experience with the removal of large CDRIE vegetations using the AngioVac system, as an alternative to conventional surgery. We retrospectively reviewed all infected lead extractions performed with a prior debulking using the AngioVac system, between October 2016 and April 2022 at our institution. A total of 13 patients presented a mean of 2(1) infected leads after a mean of 5.7(5.7) years from implantation (seven implantable cardioverter-defibrillators, four cardiac resynchronization therapy-defibrillators, and two pacemakers). The AngioVac system was used as a venous–venous bypass in six cases (46.2%), venous–venous ECMO-like circuit (with an oxygenator) in five (38.5%), and venous–arterial ECMO-like circuit in two cases (15.4%). Successful (>70%) aspiration of the vegetations was achieved in 12 patients (92.3%) and an intraoperative complication (cardiac perforation) only occurred in 1 case (7.7%). Subsequent lead extraction was successful in all cases, either manually (38.5%) or using mechanical tools (61.5%). The AngioVac system is a promising effective and safe option for large vegetation debulking in CDRIE. Planning the extracorporeal circuit design may represent the optimal strategy to enhance the tolerability of the procedure and minimize adverse events.

Transcatheter vacuum-assisted left-sided mass extraction with the AngioVac system.

To study the safety and efficacy of AngioVac for left-sided transcatheter vacuum-assisted mass extraction (TVME). The AngioVac system is approved for right-sided TVME and has emerged as an effective and safe alternative for open surgical treatment. The use of the AngioVac device for aspiration of left-sided TVME has been limited. Consecutive patients from two Michigan centers who underwent left-sided TVME were included. Data on patient demographics, procedural information, in-hospital and follow-up events were collected through electronic medical records review. Technical success was defined as aspirating of 70%-100% of the material. Ten patients (mean age 58.3 [±17.3] years, 50% male) were included. Indications for TMVE were in large for recurrent embolic events. All patients underwent bilateral cerebro-embolic protection using the Sentinel device. The total mean procedure time was 192.5 (±47.5) minof which the meantime for active aspiration (bypass time) was 9.3 (±4.2) min. The circuit configuration was: arteriovenous (AV) in fourcases and arterioarterial (AA) in six cases. Successful aspiration was achieved in 80% of cases. No complications were reported (range follow-up 1-16 months). Our small case series demonstrates the feasibility and safety of the AngioVac system in left-sided mass extraction. Larger trials are needed to further demonstrate its effectiveness and safety and potentially apply for on-label use.

Successful visible thrombus aspiration in ST-segment elevation myocardial infarction: associated factors and the clinical impact.

Thrombus aspiration (TA) has been considered a procedure for controlling distal emboli and improving microvascular perfusion. However, current guidelines classify routine TA as class III recommendation, and it has been reported that the efficacy of TA is limited because of the relatively high incidence of failure in retrieval of thrombotic material. The aim of this study was to explore patient characteristics and procedural factors associated with successful TA in ST-elevation myocardial infarction (STEMI) and to assess the clinical impact of successful TA. This single-center retrospective study enrolled 158 STEMI patients who underwent TA as initial recanalization. Factors associated with successful TA, which was defined as retrieving any visible material by aspiration catheter, were explored, and angiographical and short-term outcomes were assessed. In 146 cases (92.4%), the aspiration catheter reached the culprit lesion. Successful TA was achieved in 72 cases (45.6%). The single angiographical characteristic of successful TA was a higher Thrombolysis in Myocardial Infarction grade before TA. Among the procedural characteristics, the rate of successful TA was higher with a 7-French aspiration catheter compared with the rate with a 6-French catheter (57.1% vs. 29.9%, P = 0.01). Thrombolysis in Myocardial Infarction grade 3 flow was more frequent in patients with successful TA immediately after TA (36.1% vs. 16.3%, P = 0.006) and at final angiography (91.7% vs 79.1%, P = 0.04) compared with the grade in patients without successful TA, respectively. The use of a larger aspiration catheter may be effective in retrieving visible thrombus material, and successful TA led to better angiographical results.

Кәсіби әлеуметтену: студент жастардың табысты мансаптық бағдары

The article discusses the features of building a successful career in the process of studying at a university. These features of overcoming crisis situations in the future profession determine the factors of the development of anti-crisis competencies for the growth of successful career aspirations. The research problem is caused by the role and essence of centered support of students at the stage of studying methods of overcoming crisis pedagogical situations, as well as conducting a detailed analysis of the psychological features of the interaction of emotion and intelligence as potential opportunities of pedagogical management at the stages of building career orientation. The relevance of the topic is determined by the fact that the future specialist does not have a clear understanding of the importance of the process of integrating human consciousness into the social system as part of a successful career and activity. Summarizing the results of the study allowed us to formulate the main conclusions and outline the prospects for further scientific search for changes in the main activities of universities and the reconstruction of provisions to increase the flexibility of general cultural, scientific and professional training of students, the introduction of special psychological conceptual foundations to stimulate their personal career growth.

Recurrent thrombosis of liver transplant artery: diagnosis and staged minimally invasive treatment

The paper presents a clinical study of a 53-year-old patient who underwent liver transplantation complicated by proper hepatic artery thrombosis. No clinical or laboratory signs of the complication were observed. The disruption of arterial blood supply to the transplant was established on day six following surgery by means of routine Doppler ultrasound. Following successful selective endovascular thrombus aspiration and balloon dilation, the arterial blood flow was restored. However, one day later, the thrombosis recurred. Hepatic revascularization was achieved through thrombus re-aspiration and the proper hepatic artery stenting. In the subsequent postoperative period, no complications were observed. The paper analyzes possible causes of thrombosis and recurrent thrombosis, as well as reviewing modern literature.

Promoting Comprehensive Reform of Vocational School Education with Innovative Management

With the advent of the era of big data, in order to meet the training needs of social talents, the field of education is also undergoing continuous reform and innovation. After continuous exploration and discovery, schools need new management measures and ideas to promote all-round development, especially vocational schools are bearing the responsibility of training skilled talents. How to cultivate talents to meet the needs of social development, employees to meet the needs of enterprises, and students to meet the aspirations of success, are all the goals of vocational schools. In the past few years, vocational schools have been exploring ways of educational reform through school enterprise cooperation, integration of industry and education, and collaborative education. With the coming of industry 4.0 era, vocational education has entered a new round of development and will face new opportunities and challenges. Therefore, in the form of deepening the comprehensive reform of vocational education, vigorously promoting innovative management methods will certainly promote the comprehensive reform of education in the true sense of vocational schools.