Objective To evaluate the application of clinical Screening Tool for the Assessment of Malnutrition in Pediatrics(STAMP), and to investigate the nutritional risks of inpatient children with gastroenterological diseases in Sichuan province and their associated clinical characteristics and the features of hygiene economics. Methods STAMP was utilized for nutrition screening of inpatient children with gastroenterological diseases in Chengdu Women and Children′s Central Hospital from January 2015 to March 2017.All the enrolled children were divided into 3 groups accor-ding to the STAMP scores: low risk group (LR group), moderate risk group (MR group) and high risk group (HR group). Clinical and economic data were compared among 3 groups. Results A total of 3 672 assessments were accomplished, including 2 372 times for males and 1 300 times for females( 5 years old: 848 times). Among them, 147 children were identified as LR(4.00%), 2 296 children as MR (62.53%), and 1 229 children as HR (33.47%). Statistically significant differences were observed among 3 groups in average length of hospital stay (P 0.05). Malnutrition rate was 4.08%(6/147 cases) in LR group, 2.05%(47/2 296 cases) in MR group and 31.90%(392/1 229 cases) in HR group, respectively, and among them 146 patients were diagnosed as severe malnutrition.Digestive tract infections were the most common diseases in MR group(66.33%, 1 523/2 296 cases) and HR group(68.27%, 839/1 229 cases). Moreover, children with stomatitis, gastrointestinal postoperation, acute pancreatitis, inflammatory bowel disease, esophageal diseases, digestive malformations, cyclic vomiting, malnutrition, and acute intestinal obstruction were all in HR group. Conclusions Nutritional risk is likely to raise the burden of disease.STAMP is applicabile clinically when it is utilized for nutrition risk screening of inpatient children with gastroenterological diseases in Sichuan province and provides evidence for nutrition support treatment. Key words: Nutrition risk screening; Screening Tool for the Assessment of Malnutrition in Pediatrics; Gas-troenterological disease