The development of artificial aggregates (AAs) significantly reduces carbon emissions of concrete production since the aggregates account for about 70% volume of all concrete ingredients. Therefore, a type of low-carbon AAs was prepared with full solid wastes of biomass ash (BA) and slurry waste (SW) through a pelletizing technique and carbonation curing methods. This study focused on evaluating the feasibility of AAs produced by the synergistic effect of BA and SW; identifying and optimizing the pelletization parameters through the response surface methodology (RSM) with experimental tests; analyzing the effects of blending amounts of BA on the properties of AAs; discussing the improvement of carbonation curing methods for AAs production; assessing the properties of the prepared lightweight concrete (LWC) with AAs. The results indicate the addition of 20wt% BA lightened the bulk density of AAs by about 13% but weakened strength by nearly half due to its porous characteristics. The appropriate incorporation of 5wt% BA could improve the individual pellet and cylinder compressive strength by about 2% and 16%, respectively. AAs cured in pressurized carbonation of 3 d and wet carbonation of 10min demonstrated similar enhancement effects. Pressurized and wet carbonation curing showed respective superiorities in terms of improving effect and curing efficiency. The effects of inclination angle and moisture content on the average particle size are more significant than those of rotation speed, while rotational speed has a dominant effect on the bulk density. RSM simulations identified the optimal inclination angle, rotation speed, and moisture content as 45°, 38.5r/min, and 37.5%, respectively. The LC40 high-strength LWC can be prepared by using full substitution pre-wetting AAs.