Labor interventions especially artificial rupture of the membranes and/or oxytocin administration, are very common worldwide. The recent international guidelines aim at restricting them to their medical indications as they can be associated with adverse outcomes. We aim at analyzing the changes in the rates of labor interventions in parallel of the caesarean section rate in France. Among the population of the French perinatal surveys of 2010 and 2016, we included all women delivered of a live term (≥ 37 WG) singleton fetus in cephalic presentation. Three indicators were defined: the use of oxytocin infusion, the use of artificial rupture of the membranes, and the combination of both during labor. As labor interventions are described as reducing the rate of caesarean section the evolution of its rate was studied in parallel. The population was divided into five sub-groups: spontaneous labor, nulliparous women, previous caesarean section, low obstetrical risk and low obstetrical risk with standard care. We compared the rates of the three labor intervention indicators between 2010 and 2016, in the study population and in the subgroups. Multivariable analyses adjusting for the characteristics of women, the maternity status and the maternity size were performed. The rates and indications of caesarean section were compared between 2010 and 2016. Labor interventions were significantly less frequent in 2016 when compared to 2010 in the study population and in each subgroup. In the study population in 2016, oxytocin was less administered (64.7% vs. 52.8%, p<0.01); artificial rupture of the membranes less performed (54.9% vs. 44.4%, p<0.01) and the combination of both interventions less frequent (39.5% vs. 26.9%, p<0.01) when compared to 2010. In parallel, the rate of caesarean section during labor remained stable between 2010 and 2016 (respectively 9.6% vs. 9.8%, p=0.51). After adjustment, the year of delivery (reference: year 2010) was independently associated with a decrease of all three indicators (figure). The indications of caesarean section were similar in 2010 and 2016. The decrease in medical interventions between 2010 and 2016 did not result in an increase in the rate of caesarean section in France. These results support the rationalization of medical interventions, in line with the international guidelines published in 2017.