The exploration and development theory and technology of marine shale gas with shallow burial depth of 3500 m in South China has become mature after more than 10 years of practice. In order to continuously promote the exploration and development of shale gas in China, based on the research results of many scholars, combined with production practice, the main characteristics of marine shale gas in China and the main theory and technology of exploration and development are further summarized. The results show that: (1) The basic characteristics of marine shale gas in southern China are marine deep-water shelf deposition, and organic-rich shale is distributed continuously in a large area; The organic matter is stored in situ after high thermal maturity gas generation, and the gas content of shale is affected by late tectonic activity; The reservoir space is dominated by nano-scale pores, and the reservoir is super-tight and ultra-low permeability, which has no natural productivity without well stimulation; Bedding and natural fracture affect the productivity of shale gas wells; The mechanical properties of shale rock determine the effect of horizontal wells. In the early stage of well production, the production rate is high and the decline is fast, while in the middle and late stage, the rate is low but the production cycle is long. (2) Based on the above characteristics, the theory of “sweet spot” and “sweet interval” of shale gas and the theory of effective development of artificial gas reservoir are established, that is, the sedimentary and tectonic interaction forms the “sweet area” or “sweet spot” of marine shale gas. Gas productivity is determined by geological and engineering factors, so the “sweet spot” must be found to develop. By constructing artificial gas reservoir through “making an artificial high permeability area, and reconstructing a seepage field”, the effective development of ultra-tight and low permeability shale gas reservoirs can be realized. It is the most effective technique for shale gas development to accurately create “transparent geological body” of reservoirs based on geology-engineering integrated evaluation technology and establish artificial gas reservoir through multi-stage fracturing technology. (3) The overpressure area in the southern Sichuan Basin is the “sweet area” for shale gas development. The “sweet interval” of the lower Silurian Longmaxi Formation with a thickness of 3–5 m and high brittle-rich organic matter is the optimal “golden target” for horizontal wells. (4) The development leapfrog from the first generation to the second generation has been realized by the key technology of multi-stage fracturing of horizontal wells. The EUR per well of Upper Ordovician Wufeng Formation and Longmaxi Formation in southern Sichuan has increased from 0.5 × 108 m3 in the initial stage to 1.0 × 108–1.2 × 108 m3 at present with a buried depth of shallower than 3500 m. (5) The effective area favorable for shale gas development in southern Sichuan is 2.0 × 104 km2, and it is estimated that the proven geological reserves of shale gas can reach 10 × 1012 m3. It is preliminarily predicted that the shale gas production in China will exceed 300 × 108 m3 in 2025 and reach 400 × 108 m3 in 2035.