This paper proposes a methodology on reliability and cost minimization of the electricity produced by Renewable energy sources. The approach is to use Hybrid Renewable Energy Systems, which involves integrating various renewable sources. The objective of this study is to address these challenges by HRES method in the state of Karnataka. In Karnataka, there has been large scale curtailment of renewable energy generation due to the various structural issues. This study would give a solution to reliability and cost related issues faced by this state. For the study a Mathematical Model has been developed using Feed Forward Neural Network (FNN) and Chemical Reaction Optimization algorithms. Chemical reaction Optimization model is chosen to remove biases of the Artificial Neural Network Model of FNN. This model will be used to simulate interaction between Hybrid Renewable Energy Systems. The result of the study will provide a power system with high & optimized renewable energy output in the state of Karnataka, India which will be reliable and cost effective.