The accumulation of As in biomass of crops can negatively affect human health via the food chain. This research is focused on the biomass growth and mitigation of As accumulation in roots, shoots, and grains of pea in high As soil amended singly, with each of arbuscular mycorrhizal fungi (AMF), biochar (BC), selenium (Se), silica gel (Si-gel), and sulfur (S). Root, shoot, and grain masses were found higher in pea grown in As soil amended with each of AMF, Se, Si-gel, and S. Amendments with BC was found less effective. Arsenic in grains was reduced by 66–76% in treatments with AMF, Se, Si-gel, and S. It is recommended that soil amendments with AMF, Se, S, and Si-gel to be used in field trials for effectiveness in multiple crops. • AMF, biochar (BC), selenium (Se), Si-gel and S reduced arsenic (As) uptake in pea crops. • Arsenic in grains was reduced by 66–76% in treatments with AMF, BC, Se, Si-gel, and S. • Soil amendments with AMF, BC, Se, Si-gel and S increased biomass of pea under As stress. • AMF, Se, Si-gel and S have a great potential in alleviating As toxicity in peas.