Arkhangelsk Region Research Articles

The results of ecological variety testing of seed peas in the conditions of the Arkhangelsk region

Field peas (Pisum sativum L.) are the most important leguminous crop for the northern regions of Russia, used for green cattle feed. The experience in the variety study of field peas was laid on the basis of N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences in 2021-2023, where the productivity and nutritional value of six new varieties of field peas of various origins were evaluated: Tyumenets, Frigate, Boar, Veles, Tan, Varys. The research was carried out according to the methodological guidelines “Methodology of the State Commission for Variety testing of agricultural crops”. Peas were grown in a single-species crop. The aim of the work was to evaluate varieties of seeded peas of various origins in terms of feed productivity and nutritional value and to identify the most adaptive to the conditions of the Arkhangelsk region. The growing season for the green mass varied from 36 to 41 days, the yield of the green mass from 17.9 to 35.5 t/ha. As a result of the conducted experience, precocious productive varieties of field peas with high biochemical parameters were identified – Veles, Wild Boar, Frigate, Tan. According to the main economically valuable characteristics, the Tan variety stood out. It has been established that it is effective to grow new varieties of field peas for green fodder in extreme climatic conditions.

АНАЛИЗ РЕЗУЛЬТАТОВ ПИЛОТНОГО ВНЕДРЕНИЯ ФГИС ЛК АРХАНГЕЛЬСКОЙ ОБЛАСТИ

The article highlights the relevance of the research topic related to the digitalization of the forest complex, a new stage of which was the development and implementation of FGIS LC. The object of the study is the process of implementing FGIS LC in the Arkhangelsk region. The purpose of the study is related to the fact that the results of the implementation of FGIS LC in the Arkhangelsk region as a pilot project are subject to in-depth analysis and study. Analytical materials, reports of specialized institutions and scientific articles have been studied on the topic of the study. Both qualitative and quantitative methods were used in the study. Among the qualitative methods, observation, interviews, professional assessments and testing were used. Quantitative methods such as questionnaires and monitoring were applied together with them. Methods of analysis and synthesis, comparison, as well as an empirical approach were used to analyze various sources of information. The results of the study were the analysis of foreign information systems and services for forest accounting, timber harvesting, and assessment of the architecture, structure and functionality of FGIS LC, analysis of the process of implementing FGIS LC in the Arkhangelsk region. The FGIS LC system is based on technological processes that include both automated ones, maintains a register of documents and related data, and provides continuous monitoring of the state of forest management based on accepted documents and changes made to them. The architecture of FGIS LC includes three segments that logically combine all the functions of the system: the industry segment, the integration segment, and the public segment. Expert discussions with experts on the implementation of FGIS LC in the Arkhangelsk region allowed us to identify a number of basic errors and the way to solve them. Testing the functionality of FGIS LC in the Arkhangelsk region, focusing on solving the main issues that require elaboration and improvement of the system. The analysis of the experience of implementing FGIS LC in the Arkhangelsk region revealed the best practices and difficulties of working with this system. Such an analysis is necessary, as it helps to optimize the processes in the work of enterprises and government agencies

Assessment of anthropogenic impact on the territory of the village of Solovetsky (Solovetsky archipelago, Arkhangelsk region)

Assessment of anthropogenic impact on the territory of the village of Solovetsky (Solovetsky archipelago, Arkhangelsk region)

Characteristics of shock-producing injuries in victims of traffic accidents on federal, regional and local highways in the Arctic zone of the Arkhangelsk region

Relevance. Motor vehicles are a highly traumatic type of transportation and the cause of traffic accidents with medical consequences, including large numbers of severe shock-associated injuries. Federal, regional and local highways differ significantly by the type and quality of pavement, technical maintenance and upkeep, which affects the safety conditions for drivers and pedestrians.The objective is to analyze shock-producing injuries in victims of road accidents on federal, regional and local roads in the Arctic zone of the Arkhangelsk region to characterize the incidence, type and severity of traumatic injuries.Methodology. A set of criteria for case series description was used to analyze medical records of 72 victims presented with shock-producing injuries as a result of road accidents on federal, regional and local roads of the Arkhangelsk region who were admitted to a level 1 trauma center of the Arkhangelsk Regional Clinical Hospital. The injury type was characterized according to A.V. Kaplan et al. classification. We identified the following types of injuries: isolated (single lesion), multiple (several foci in a single body area), and combined (several foci in different body areas) injuries. Combined injuries were split in 3 categories according to the criteria developed by E.K. Gumanenko et al.: severe combined injuries, multiple injuries, and extremely severe multiple injuries. The injury severity was assessed by the Injury Severity Score. The STATA version 12 software was used for statistical analysis of the results.Results and discussion. In the Arkhangelsk region, 70 % of the road accidents resulting in shock-causing injuries occurred on the M-8 ‘Kholmogory’ federal highway. These accidents are largely represented by car-to-car collisions (65 %), where regional and local roads are typically characterized by car collisions with pedestrians (52 %). In case of the federal highway accidents, the overwhelming majority of victims with shock-causing injuries have combined injuries (90 %); this rate decreases to 65 % (p < 0.001) for regional and local roads. On the M-8 ‘Kholmogory’ federal highway, accidents are show a 1.4 times higher risk of the most severe mechanical injuries – multiple injuries – than accidents occurring on regional and local roads. Thus, in the Arkhangelsk region, medical treatment organizations require stronger workforce and logistics support; mobile highway safety points should be set-up along the M-8 ‘Kholmogory’ federal highway to ensure prompt emergency medicacare, both on federal and regional or local roads. Conclusion. By incorporating the public status of a road into the analysis of occurrence, type and severity of shock injuries in victims of road accidents in the Arkhangelsk region, we were able to substantiate proposals to pursue reduction in the injury rates. The M-8 ‘Kholmogory’ federal road requires drivers to unconditionally observe and comply with traffic rules regarding over taking and speeding through extensive deployment of both stationary and portable video recording devices, as well as quadcopters. As for regional and local roads, special attention should be granted to pedestrians’ behavior, such as walking along the hard shoulders of highways, crossing the road at night time, as well as impaired visibility conditions. Intoxicated pedestrians constitute a very specific category. The basics of safe behavior on roads and highways should be nurtured in the preschool and school age.

Психологическое здоровье и духовно-нравственные ценности молодых людей призывного возраста в контексте деструктивного информационно-психологического воздействия

<p>The work is aimed at studying the psychological health and spiritual and moral values of young people of conscription age in the context of the destructive information and psychological influence. The results of an empirical study conducted in 2024 on the territory of 4 regions of the Russian Federation are presented: Arkhangelsk, Kaliningrad, Leningrad and Murmansk regions. The total number of respondents was 1,050 young people of draft age aged 16 to 20 years. The following were used in the study: the author's questionnaire “Information and psychological impact”; the questionnaire “Motivational structure of information activity”; the questionnaire “Spiritual personality”; the methodology “Individual model of psychological health”. The obtained results allow us to say that, on average, young people of conscription age often encounter content in the Internet space that has a destructive informational and psychological impact, while they have a fairly high degree of trust in this content. It is noted that young people exposed to destructive information may experience social isolation, mistrust and aggression, which prevents them from forming healthy social connections, leads to a decrease in psychological health and has a destructive effect on internal values and spiritual and moral guidelines. In such conditions, a more pessimistic perception of the world is formed, which undermines the basic principles of spirituality and morality, in particular, such as sincerity, politeness and the pursuit of truth.</p>

Materials for the study of lichens of the natural recreational complex ‘‘Pine Forest of the Yagry Island’’ (Arkhangelsk Region)

Materials for the study of lichens of the natural recreational complex ‘‘Pine Forest of the Yagry Island’’ (Arkhangelsk Region)

Естественное воспроизводство населения на Европейском Севере России в период с 1980 по 1990 год (по материалам Архангельской и Вологодской областей)

The Arkhangelsk and Vologda regions are located in the central part of the European North of Russia and are distinguished from other constituent territories by similarity of their ethnodemographic processes. This paper aims to identify the main trends and factors of birth rate, mortality, and rate of natural increase in the Arkhangelsk and Vologda regions from 1980 to 1990. The methodological basis of the study is the institutional approach, which allows one to identify the influence of state and socio-economic institutions on the demographic processes. The author studied statistical materials and records (archival and published) containing data on birth rate and mortality in the European North of Russia and country as a whole during the period of 1980–1990. It is demonstrated that the increase in birth rate in the Arkhangelsk and Vologda regions during the decade in question was caused by a growing number of women of reproductive age, government measures to support families introduced in 1981, and the effect of the anti-alcohol campaign. At the same time, mortality in the European North of Russia was growing and its structure was changing: the proportion of alcohol-related deaths and that of deaths from external causes increased, which was associated with the changing economic situation in the second half of the 1980s. As a cumulative result of birth rate and mortality, under the influence of the systemic crisis the rate of natural increase (after its active growth in the first part of the period) from 1987 to 1990 reached a minimum level. Having compared the rates of natural increase in the regions under study with those in Central Russia, the author came to the conclusion that the population of the Arkhangelsk and Vologda regions had not entered the depopulation stage by the end of the period in question, whereas in Central Russia, e.g. the Kostroma and Vladimir regions, depopulation began in the second half of the 1980s.

Наш ответ «Минитмену» (о проведении летных испытаний межконтинентальной баллистической ракеты РТ-2П)

The article attempts to reconstruct the development flight tests of the RT-2P intercontinental ballistic missile that were performed at the 53rd Research Proving Ground of the USSR Ministry of Defence in 1969–1972. The paper aims to, through the use of the historical-systematic and problem-chronological methods, consider the creation of test formations and the experimental test base as well as the missile’s flight tests as a single process of development flight testing. The use of a multidisciplinary approach allowed the author to view the testing process as a single man–machine–environment system that operated in the Soviet Union during the period of developed socialism. The study is based on the literature of Arsenal Design Bureau, archival sources, documents of military test units, as well as reminiscences of the participants in the events, including those that had not been published before. The paper provides updated information on the establishment, improvement and use of the experimental test base, changes in the structure and composition of test formations, as well as test results. The author points out that experimental test bases should be built in advance, taking into account the existing facilities, with the direct participation of operating organizations. While searching for optimal applications, the structure and composition of test formations can be dynamic; at the same time, working with just one type of missile appears to be the most effective way. The RT-2P missile tests resulted in the approval for service use of the first solid-fuel intercontinental ballistic missile and in the introduction of changes to the missile operating system in the Strategic Missile Forces. The findings can be used in writing a detailed history of the Strategic Missile Forces and a military chronicle of the Arkhangelsk Region, as well as in the planning of tests of promising military equipment.

Adjuvant chemotherapy for colorectal cancer: role of specialized unit

AIM: to evaluate the rate and timeliness of adjuvant chemotherapy (ACT) in patients with stage II–III colon cancer (CC) after surgery in different medical units of the Arkhangelsk region and to assess its prognostic value.PATIENTS AND METHODS: all records on patients with CC after radical surgery in 2010–2021 were extracted from the Arkhangelsk Regional Cancer Registry (ARCR). Proportions of those who received ACT, the average waiting time for ACT and survival depending on the fact of ACT in specialized oncological unit (SOU), including the Arkhangelsk Clinical Oncology Dispensary (ACOD) and non-specialized medical units (NMU). Cancer-specific survival (CSS) was assessed. The hazard ratio (HR) of death from CC was estimated by Cox regression depending on receiving ACT and the waiting time for it.RESULTS: the database included 1032 cases (538 patients with stage III and 494 with stage II patients, who had unfavorable prognosis factors). No differences were found in ACT rate among patients with stage II CC. In stage III CC, ACT was performed in 73.5% of patients operated on in the SOU and 46.3% in NMU (p < 0.0001). The median waiting time for ACT after radical surgery in the SOU was 33.5 (17.0; 43.5) days, and 46.5 (31.0; 64.5) days in the NMUs, p < 0.0001. The five-year CSS of those who received ACT was 67,2% (95% confidence interval (CI): 60.8–72.9%), and 64.1% (95% CI: 58.8–68.1%) for those who did not receive ACT, p = 0.012. Five-year CSS after chemotherapy started within 4 weeks after radical surgery was 73.2%, for the gaps 5-8, 9–12 and more than 12 weeks 70.4%, 63.7%, and 35.4%, respectively, p = 0.002. In the adjusted model, the HR for death from ROC was 3-fold higher in patients receiving ACT at 12 + weeks (HR = 2.6 (95% CI: 1.31–5.14), p = 0.006) compared with the 0–4-week interval.CONCLUSION: the study revealed lower and later incidence of ACT in NMU affected worse survival.

Follow up of clinical outcomes in type 1 diabetic patients according to the results of dynamic examination in the mobile center "Diamobil"

Background. Type 1 diabetes mellitus (T1DM) is a severe disease associated with reduced life expectancy. Understanding the causes and methods of reducing risks for this cohort is highly relevant for developing measures to reduce the number of years lost. Aim. To assess clinical outcomes: the frequency of diabetic complications, structure of mortality among T1DM patients who were examined at dynamic examination in the mobile center "Diamobil" in the Arkhangelsk region in 2005 and 2023. Materials and methods. The study was conducted on a cohort of patients with T1DM, examined at "Diamobil" in Arkhangelsk region in 2005 (n=319), with dynamic follow up of vital and clinical status, clinical parameters and frequency of complications over an 18-year period. At 2023, out of 319 people in the primary cohort – 61 patients died, 206 were in "alive" status and 52 were removed from analysis. Statistical analysis is performed with the help of Statistics v.13.3. Results. In the dynamic cohort (n=206) at 2023 median age of patients was 40 years [34; 55], duration of DM – 28 years [24; 33], percentage of women – 55%. Compared to 2005, glycated hemoglobin was comparable, there were an increase in body mass index (21.9 kg/m2 vs 25.1 kg/m2) and obesity rate from 3.1 to 11.2% (p=0.006), a decrease in estimated glomerular filtration rate (103.1 ml/min/1.73 mm2 vs 86.4 ml/min/1.73 mm2; p0.001) and increased frequency of diabetic complications: chronic kidney disease (CKD) any stage from 24.9 to 69.4%, Stage 3a CKD from 0.5 to 7.4% (p=0.003), diabetic retinopathy from 26.4 to 74.6%, diabetic neuropathy from 25.9 to 78.2% (p0.001), which reflects the long-term effect of the hyperglycemia factor. Based on the results of the analysis of mortality structure by proximal cause, it was established that the most frequent causes of death were cardiovascular disease – myocardial infarction, acute cerebral circulation disorder, heart failure and other cardiovascular diseases – 42.6%; death due to hypoglycemic and ketoacidotic coma – 3.2%, terminal cardiovascular disease – 14.8%. Deceased patients were characterized by a longer duration of DM (13 years vs 8 years), higher glycated hemoglobin (9.4% vs 8.4%), lipid profile (total cholesterol 4.77 mmol/l vs 4.41 mmol/l; TG 1.31 mmol/l vs 0.98 mmol/l) and albuminuria (70 mg/mmol vs 6 mg/mmol; p0.001). Conclusion. "Diamobil" control epidemiological studies can be positioned as the optimal method of risk cohort survey coverage for the assessment of dynamic indicators in real clinical practice.

Влияние компонентов рациона на продуктивность и функциональное состояние коров холмогорской породы

Abstract. To realize the genetic potential of dairy cows with high productivity, the qualitative composition of the feed is of key importance. The purpose of this study is the effectiveness of publicly available feed additives – “Carbohydrate-protein mixture” (1st experiment) and “Protected fat” Energizer Gold (2nd experiment) on the productivity of Kholmogory cows, on the content of fat and protein in milk, on the functional state of animals, including taking into account the bloodline of the Holstein breed. Methods. Scientific and production experiments were carried out by the pair-analogue method on 40 lactating cows of the Kholmogory breed of Agrofirma Kholmogorskaya LLC, Arkhangelsk region. The scientific novelty consists in obtaining new knowledge about the effect of feed not only on productivity and fat and protein content in milk, but also on the functional state of Kholmogory cows, including those with different percentages of Holstein blood. Results. When assessing the average group results of daily milk yield, a positive effect was established from including it in the diet according to the feed recommendations. At the same time, the “Carbohydrate-protein mixture” increases the protein content in milk, no increase in the fat content of milk, stated in the recommendations for the use of “Protected fat”, was noted. A decrease in the fat to protein ratio in milk, reflecting the functional state of the cows, was noted, below the standard results in Experiment 1 already from the second, and in Experiment 2 from the fourth control milking, preserved until the end of the study. The best effect on the studied indicators for both feed additives was noted in the Kholmogory cow breed with less Holstein blood.

Фаутность еловых древостоев северо-таежного района Архангельской области

The results of studying the defectiveness of spruce forests in the northern taiga zone of the Arkhangelsk Region are presented. Defectiveness has a significant impact on the sanitary condition, marketability and sustainability of forest plantations. The study has been conducted from 2020 to 2023 using materials obtained from sample plots laid in mature spruce plantations, modal in terms of basic taxation parameters. Before starting the field work, the cartographic databases have been studied. The sample size has been determined by the variability of the taxational diameter of the main species and the experiment accuracy. In each test area, all trees have been enumerated by species, diameter at a height of 1.3 m and by condition categories. For each tree, the presence of defects affecting marketability and fruit bodies of wood-destroying fungi has been noted. To determine the age of the trees in the sample plot, core samples have been taken from the root collar. To study the patterns of the defectiveness spread and obtain mass material, statistical survey sites have been laid on fresh cuttings. When rot has been detected on the stump, the diameter of the rot has been measured and its type and stage have been determined. The age of the trees has been determined by the annual rings on the stumps. In the presence of rot, age has been determined by correlation with the diameter of the stump. The trees have then been grouped by their respective age classes. In the course of the research, defectiveness indicators have been studied and analyzed in various forest growth conditions. It has been revealed that with an increase in the age class, the occurrence of all defects increases. The most obvious dependence has been recorded for rots. The amount of rots varies from 5.1 to 29.0 %, depending on the type of forest growth conditions. The proportion of rots decreases with the deterioration of forest conditions. The most common wood-destroying fungus is the root sponge (Heterobasidion annosum (Fr.) Bref.). There is an increase in the incidence of wood-destroying fungi in trees with increasing diameter. The average stage of butt rot has been 2.8. The study of the defectiveness will improve the accuracy of assessing the resource potential of coniferous plantations in the Arkhangelsk Region.

Polymorphism of genes involved in the regulation of blood pressure in elderly residents of the Arkhangelsk region

BACKGROUND: Living in the northern climate is associated with increased cardiovascular stress, which highlights the necessity for the study of candidate genes associated with the risk of cardiovascular diseases in both the native population and newcomers. Polymorphic loci of the renin-angiotensin system, NO-synthase, and endothelin-1 system genes have been identified as contributors to cardiovascular dysfunction and age-related blood pressure shifts. It is therefore crucial to assess the genetic polymorphism in the elderly population. AIM: To compare frequencies of gene alleles and genotypes involved in blood pressure regulation, including angiotensinogen AGT (rs699 and rs4762), angiotensin 2 type 1 receptor AGTR1 (rs5186), angiotensin converting enzyme ACE (rs4646994), endothelial NO synthase NOS3 and endothelin-1 EDN1 (rs5370) genes, in the native and non-native elderly population of the Arkhangelsk region. MATERIALS AND METHODS: A cross-sectional study was conducted in a random sample of Arkhangelsk residents between the ages of 60 and 74 years (N=604, with 36.4% of males). The molecular genetic analysis was conducted to determine the alleles and genotypes of six genes that are involved in blood pressure regulation. The Stata 18.0 software was used to assess the deviations of empirical genotype distributions from the predicted Hardy–Weinberg equilibrium and to compare the empirical distributions between the study groups. RESULTS: Alleles associated with the risk of cardiovascular diseases were minor in the study population. The genotype frequency distributions for the analyzed genetic variants were consistent with the Hardy–Weinberg principle, with the exception of the T704C variant of the AGT gene (rs699) in the native participants. The allele and genotype frequency distributions in the study sample were found to be similar to those reported worldwide and in European Russia. One exception was AGTR1 gene A1166C frequencies, with their 95% confidence intervals falling below the global level for both native and non-native elderly residents of the Arkhangelsk region. This may suggest that this allele is a selection variant associated with adaptation to the climate of the northern regions. CONCLUSION: The genetic polymorphism in blood pressure regulation was found to be similar between the native and non-native populations of the Arkhangelsk region. However, the AGTR1 gene A1166C frequency among the native population and newcomers was found to be lower than that observed globally.

State of thermophylic ichthyofauna in the water bodies of Arkhangelsk Oblast: Report 2. Biological characteristics of fish

The biological characteristics of warm-water fish species living in water bodies of the Arkhangelsk region are presented. Changes in size and mass parameters, age and sex structures and reproductive ability of the Severodvinsk sterlet in the temporal aspect were revealed. It has been established that it has good growth rates, a reserve in replenishing the spawning stock and a stable state of the natural reproduction system. The biological parameters of blue bream and rudd, rare species of fish that live in the lakes of the Kenozersky National Park, as well as a number of reservoirs in the Arkhangelsk region, were obtained. The biological characteristics of species that appeared in the river basin are considered. Northern Dvina as a result of self-dispersal - white-eye and asp, as well as the nutrition and feeding relationships of white-eye with native fish species. The attention of specialists to these alien fish species is due to the need to develop an environmental forecast for the development of the situation with their numbers in the context of ongoing global warming.

Нормативные интервалы и цифровое приложение для оценки параметров эхокардиографии детей Архангельской области

Objective interpretation of echocardiography results in the paediatric population is an urgent issue due to the difficulties in identifying the correct cardiovascular allometric relationship. A wide use of existing echocardiographic nomograms in paediatric cardiology is problematic due to the lack of clear data on the subjects’ regional affiliation, the volume of samples analysed, and the insufficient number of Russian studies in this sphere. The purpose of the study was to develop reference intervals for echocardiography parameters of children living in the Arkhangelsk Region and to automate the process of interpretation of the results by creating a digital application. Materials and methods. We analysed 3811 echocardiography protocols of children living in the Arkhangelsk Region aged from 1 to 15 years with no signs of organic pathology of the cardiovascular system or heart rhythm disorders. Results. Using echocardiography data, we developed reference intervals for morphometric parameters of the heart for children aged 1 to 15 years living in the Arkhangelsk Region. The research applied the Z-score approach based on the empirical determination of the degree of abnormalities by the standard deviation from normal values obtained during the examination of a large population of healthy individuals. Reference intervals of echocardiography parameters were determined using body surface area as the dependent variable. The values were automatically calculated in our digital application that allows one to increase the accuracy and efficiency of interpretation of cardiac ultrasound parameters. The results of studying the differences between the reference values in Russian and foreign studies and the obtained regional norms indicate that the hearts of children living in the Arkhangelsk Region are statistically significantly smaller in size. The practical use of the digital application created by us in functional diagnostics will allow doctors to objectivize the measurements of morphometric parameters of the heart and reduce overdiagnosis.

Взаимосвязь процессов фибринолитической активности и эндокринной регуляции в ходе адаптации к физической нагрузке

Corticosteroids are one of the key hormones contributing to the development of general adaptation syndrome. The initial phase of stress changes in the haemostatic system during adaptation to physical activity is hypercoagulation, which is dangerous for the body due to increased thrombosis. If the exercise is adequate for the body’s adaptive potential, the next phase of stress changes is resistance, which includes hypocoagulаemia and increased fibrinolytic activity. This protective response is provided by the mobilization of oxytocin and kinin–kallikrein system as well as anticoagulation and fibrinolytic factors. Intensified fibrinolysis is accompanied by an increase in plasmin activity, greater action of plasminogen activators, and antiplasmin inhibition. In conditions associated with increased fibrin formation, a reactive rise in plasmin levels is observed; at the same time, the concentration of the plasmin–antiplasmin complex increases. When the load exceeds the body’s adaptive capabilities, a state of hypercoagulation develops, accompanied by the inhibition of the anticoagulant system and fibrinolytic activity. The purpose of this article was to analyse the relationship between hormonal status and fibrinolytic activity under physical load during the training process in athletes in order to identify general patterns of the body’s adaptation to physical activity. Materials and methods. The study involved 98 athletes aged between 16 and 25 years doing various sports and living in a subarctic region of Russia (Arkhangelsk Region). Their median age was 19.5 years. Physical activity was considered as a stressor; the state of the haemostatic and endocrine systems was studied. Using the enzyme immunoassay method, the concentrations of thyroidstimulating hormone, free thyroxine, cortisol, testosterone, and plasmin–antiplasmin complex in the venous blood were determined. Results. The study revealed activation of the hypothalamic-pituitary-adrenal axis in athletes, manifested in an increase in cortisol serum levels. This increase confirms the assumption of the predominance of catabolic reactions in athletes. A direct relationship between the concentrations of cortisol and plasmin-antiplasmin complex (Spearman correlation: rS = 0.229; p ≤ 0.05) was established, demonstrating the uniformity of these markers during adaptation to physical load.

Расчет плотности гидросети равнинных арк­тических и субарктических территорий России по цифровой модели рельефа с использованием ГИС-технологий (на примере Архангельской области)

The authors have developed a program for calculating the density of the channel network of the current relief using SAGA GIS modules to identify low-amplitude tectonic disturbances in the sedimentary cover of the platform arctic and subarctic territories of the Russian Federation. The program allows automating the calculation of the drainage network density using the sequential execution of standard GIS package modules. The calculation takes into account not only the drainage network, but also linear depressions of the relief, which makes it possible to identify structures with increased activity of current tectonics. The authors have calculated the density of the channel network of the representative territory (Arkhangelsk Region) with different “windows”. Comparison of the results with tectonic disturbances have shown a high degree of coincidence. The proposed methodology is applicable to the plain arctic and subarctic territories of the Russian Federation.

Информативность интегральных гематологических индексов при оценке иммунного статуса (на примере жителей Архангельской области)

In the North, humans are exposed to a number of unfavourable natural and climatic factors, which can negatively affect the body’s functions. In the process of adaptation, homeostasis is maintained by imposing a strain on the relevant organs and systems, including the immune system, whose disruption is usually accompanied by changes in the cellular composition of the pool of peripheral blood leukocytes and is reflected in leukogram parameters. The purpose of this study was to establish the informative value of integral haematological indices for preventive detection of changes in the immune status. Materials and methods. We examined 75 volunteers, including 52 residents of Konosha settlement and 23 residents of the city of Arkhangelsk (mean age 42 ± 10 and 44 ± 14 years, respectively). The subjects’ complete blood count was performed using the Medonic M20 cell analyser (Boule Medical AB, Sweden), and their leukocyte formula was calculated. The leukocyte intoxication index, nuclear index, allergization index and leukocyte shift index were calculated. Results. It was established that apparently healthy people living in the same region but in areas differing in natural and climatic conditions have statistically significant differences in the cellular composition of the leukocyte pool. In residents of the northern part of the Arkhangelsk Region (the city of Arkhangelsk), lymphocyte and band neutrophil count, as well as mean nuclear index and mean allergization index exceed the upper limits of their reference intervals. At the same time, residents of the region’s southern part (Konosha settlement) had a higher frequency of exceeding the upper limit of the reference interval of the leukocyte intoxication index. Integral haematological indices allow us to identify changes in the immune status at the preventive stage; their calculation can serve as an effective way to assess the degree of allergization, the level of endogenous intoxication and the reactivity of the immune system. Due to the simplicity and accessibility of the analysis, one can quickly obtain results and use them both for population screening and in surveillance studies.

Immune status in women after COVID-19 living in the subarctic region

Background. T cell immunity is known to play a central role in controlling SARSCoV- 2 (severe acute respiratory syndrome-related coronavirus 2) infection, so it is critical to understand its role in recovery from COVID-19 (coronavirus disease 2019), especially in the unfavorable conditions of the North.The aim. To assess the immune status of women after COVID-19 living in the subarctic region of the Russian Federation.Materials and methods. We examined a total of 50 women aged 36–46 years, including 38 vaccinated women 6 and 12 months after recovery from COVID-19 and 12 women (control group) who had not had COVID-19 and had not been vaccinated (Arkhangelsk region). We studied leukocyte count, leukogram and lymphocyte phenotypes (CD5+, CD8+, CD10+, CD16+, CD95+).Results. The contribution of monocytes to the formation of the adaptive immune response among female residents of the subarctic region decreases in those who have had mild COVID-19 and increases in those who have had moderate COVID-19. It was found that the imbalance in the formation of the immune response after COVID-19 is formed due to innate immunity (CD16+, neutrophils (r = 0.89; p < 0.001)), affects the adaptive immunity and depends on the severity of the disease and the time since recovery. The most significant contribution to the formation of the adaptive immune response was established due to cellmediated cytotoxicity (CD8+, CD16+) and the activity of apoptotic processes (CD95+) both after 6 and 12 months and does not depend on the severity of the COVID-19. The adaptive immune response formed 6 months after COVID-19 with a high level of cell-mediated cytotoxicity and activity of apoptotic processes prevailing over lymphoproliferation persists after 12 months, which indicates a tense state of immune homeostasis.Conclusion. In the examined women who had recovered from COVID-19, cellmediated cytotoxicity (CD8+, CD16+) is associated with the activation of the monocyte system, has a prolonged effect of up to 12 months and depends on the severity of the previous COVID-19 in 66.7–90 % of cases.

Роль девичника в структуре русской свадьбы Севера как динамической системы

This article examines the culture of the wedding ceremony, its most important qualities, the structure of one of its stages – the bachelorette party, the features of its holding in the Vologda and Arkhangelsk regions. It describes a special song genre used during the bachelorette party and characteristic of the Russian North – the ritual lamentations. The main research attention in the article is focused on the semantics and musical code of this part of the wedding rite. The scientific novelty of the study lies in the identification of unique aspects of the bachelorette party as part of the tradition and a comprehensive analysis of its meaning and folklore accompaniment. Unlike the existing works on these issues, the focus will be on the relationship between musical elements and cultural connotations, as well as on the role of the bachelorette party in the formation of collective identity. The article considers the transformations of the ritual phenomenon in the context of globalization, which contributes to understanding the dynamics of traditional practices and their adaptation in a modern context. The undertaken research fills an existing gap in folklore and cultural science, opening up new perspectives for the study of rituals and their significance in modern society.