We introduce and test an experimental approach to simulate elastoplastic megathrust earthquake cycles using an analogue model and apply it to study the seismotectonic evolution of subduction zones. The quasi‐two‐dimensional analogue model features rate‐ and state‐dependent elastic‐frictional plastic and viscoelastic material properties and is scaled for gravity, inertia, elasticity, friction, and viscosity. The experiments are monitored with a high‐resolution strain analysis tool based on digital image correlation (particle imaging velocimetry, PIV), providing deformation time series comparable to seismologic, geodetic, and geologic observations. In order to separate elastic and nonelastic effects inherent the experimental deformation patterns, we integrate elastic dislocation modeling (EDM) into a hybrid approach: we use the analogue earthquake slip and interseismic locking distribution as EDM dislocation input and forward model the coseismic and interseismic elastic response. The residual, which remains when the EDM prediction is subtracted from the experimental deformation pattern, highlights the accumulation of permanent deformation in the model. The setup generates analogue earthquake sequences with realistic source mechanisms and elastic forearc response and recurrence patterns and reproduces principal earthquake scaling relations. By applying the model to an accretionary‐type plate margin, we demonstrate how strain localization at the rupture peripheries may lead to a seismotectonically segmented forearc, including a tectonically stable shelf and coastal high (<20% plate convergence accommodated by internal shortening) overlying the area of large megathrust earthquake slip. Fifty to 75% of plate convergence is accommodated by internal shortening in the slope region where earthquake slip tapers out toward the trench. The inner forearc region remains undeformed and represents a basin.
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