Areas Of Human Body Research Articles

Photoplethysmography-Based Angiography of Skin Tumors in Arbitrary Areas of Human Body.

Noninvasive, rapid, and robust diagnostic techniques for clinical screening of tumors located in arbitrary areas of the human body are in demand. To address this challenge, we analyzed the feasibility of photoplethysmography-based angiography for assessing vascular structures within malignant and benign tumors. The proposed hardware and software were approved in a clinical study involving 30 patients with tumors located in the legs, torso, arms, and head. High-contrast and detailed vessel maps within both benign and malignant tumors were obtained. We demonstrated that capillary maps are consistent and can be interpreted using well-established dermoscopic criteria for vascular morphology. Vessel mapping provides valuable details, which may not be available in dermoscopic images and can aid in determining whether a tumor is benign or malignant. We believe that the proposed approach may become a valuable tool in the preliminary cancer diagnosis and is suitable for large-scale screening.

Focal slowing of nerve conduction velocity in leprosy patients unveiled through multisegmented nerve analysis.

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae), an intracellular bacillus that systematically invades the peripheral nerves. Diagnosing leprosy neuropathy is still a defying skill, and late diagnosis and treatment are still a reality. Based on the biological characteristics of M. leprae, particularly its preference for invading the Schwann cells localized at the coldest areas of human body, we hypothesized that these areas have focal demyelination that may escape detection through standard nerve conduction studies (NCSs) protocols. Twenty-five patients with confirmed multibacillary leprosy and 14 controls were accessed. A multisegmented NCS protocol (MP) was performed, targeting short segments through the coldest areas, to identify focal areas of slowed conduction velocity. The effectiveness of this multisegmented protocol was compared to the standard protocol (SP) to detect abnormalities. All leprosy patients presented an abnormal study with the MP, contrasting to 19 with the SP. The most frequent NCS pattern was an asymmetric neuropathy with focal slowing of conduction velocity, found in 23 out of 25 leprosy patients. Significant differences favoring the proposed method were observed when comparing the MP with the SP. Notably, the MP increased the sensitivity to detect abnormalities by 122%, 133%, and 257% for the median, peroneal, and tibial nerves, respectively. MP also increases sensitivity to detect focal abnormalities in the ulnar nerve. The MP protocol significantly increases the sensitivity of NCSs to detect neurophysiological abnormalities in leprosy neuropathy.

Soil biochemical inticators of initial presence of fat in different archaeological contexts

The article proposes a new biochemical approach for the reconstruction of the initial presence of fat-containing products in different archaeological contexts (ceramic vessels from burials, soil samples in different parts of the skeleton and cultural layers of archaeological sites) based on the study of qualitative and quantitative changes in the parameters of the soil microbial community, namely, specific groups of microorganisms (lipolytics), a number of lipolytic enzymes, as well as the utilization spectrum of readily available low molecular weight sub-strates. Ground samples of the studied objects were collected in the following regions: ceramic vessels — the Republic of North Ossetia-Alania and the Chechen Republic; burials — Krasnodar Krai; the cultural layer of the settlement — Lipetsk region. The number of lipolytic microorganisms and the level of enzymatic activity in the soil directly depend on the amount of the incoming substrate, in the decomposition of which they participate. After the decomposition of organic residues in the soil, a microbial and enzyme pools are formed, which can persist for a long period. The obtained preliminary data on the study of the decomposition dynamics of fatty substrates give us possibility for the reconstruction of the initial presence of fat in different archaeological contexts using the methods of soil microbiology and biochemistry. But, for a more accurate extrapolation of the results of a model experiment to archaeological objects, more points of observation in time are needed, since the introduction of substrates with different properties and composition can provoke microbial community succession in different ways. Hence, the equilibrium state of the microbial community in each variant of the experiment will be reached at different times. However, the results of the study of soils and cultural layers of archaeological sites of Bronze Age and early me-dieval time have convincingly shown the possibility of applying our approach. As we assumed, the maximum li-pase activity was found in the soil samples under the skull, chest and pelvis, i.e. in areas of human body with the highest content of fat tissues. This showed the possibility for reconstruction the original contents of the vessels from burials using the methods of soil microbiology and biochemistry. A high number of lipolytic microorganisms and lipase activity were detected only in 15–20 % of the vessels. We suggest that fat food may not have been as widely used in the funeral rite as ritual food. The study of lipase activity made it possible to clarify the features of the economic usage of the territory of archaeological site, to identify possible places for cooking.

Occluded Person Re-Identification via Defending Against Attacks From Obstacles

Due to incomplete appearance features, the identity matching of occluded pedestrians under multiple cross-camera views is a long-term challenge. Although existing re-identification (re-ID) solutions of occluded pedestrians have made significant progress, most of them achieve accurate identity matching by extracting pedestrian appearance features from unoccluded areas. However, when a pedestrian is partially blocked by the body of another pedestrian, existing methods cannot accurately determine whether the unoccluded body parts belong to the target pedestrian, which brings great difficulties to pedestrian identity matching. To alleviate this problem, this paper introduces the idea of adversarial attack into occluded person re-ID and proposes an adversarial training framework that can defend against attacks from obstacles to resist the interference of obstacles on pedestrian identity matching. Unlike existing solutions, the proposed framework is not limited to extracting features of unoccluded human body areas to achieve occluded person re-ID, but explores how to make the re-ID model more resistant to obstacles. In the proposed framework, the occluded pedestrian images are regarded as adversarial examples and used to attack model training. If the trained model can defend against this kind of attack, its generalization is significantly improved, and the above-mentioned issues are also effectively solved. Specifically, a single-branch dual-stream collaborative network is designed. With the cooperation of the pre-trained verification guidance network, the model realizes the attack and defense of adversarial samples. This work broadens research horizons in robust model design of occluded person re-ID, and expands the scope of adversarial attacks. Compared with existing solutions, a lot of experimental results confirm that the proposed solution achieves better performance on two occluded re-ID datasets and two partial re-ID datasets.

Posture Monitoring and Correction Exercises for Workers in Hostile Environments Utilizing Non-Invasive Sensors: Algorithm Development and Validation.

Personal protective equipment (PPE) is an essential key factor in standardizing safety within the workplace. Harsh working environments with long working hours can cause stress on the human body that may lead to musculoskeletal disorder (MSD). MSD refers to injuries that impact the muscles, nerves, joints, and many other human body areas. Most work-related MSD results from hazardous manual tasks involving repetitive, sustained force, or repetitive movements in awkward postures. This paper presents collaborative research from the School of Electrical Engineering and School of Allied Health at Curtin University. The main objective was to develop a framework for posture correction exercises for workers in hostile environments, utilizing inertial measurement units (IMU). The developed system uses IMUs to record the head, back, and pelvis movements of a healthy participant without MSD and determine the range of motion of each joint. A simulation was developed to analyze the participant's posture to determine whether the posture present would pose an increased risk of MSD with limits to a range of movement set based on the literature. When compared to measurements made by a goniometer, the body movement recorded 94% accuracy and the wrist movement recorded 96% accuracy.

Inexpensive bioluminescent genosensor for sensitive determination of DNA damage induced by some commonly used sunscreens

Sunscreens (SSs) are highly applied all over the world on large areas of human body. Benzophenone chemical group constitute a major part in most SSs. Benzophenones are reported to induce changes in nucleic acids upon UV-irradiation. These alterations may potentially lead to DNA mutation, cell apoptosis, and eventually skin cancer. This work compares the kinetics of the induced DNA damage by some SSs after UV-irradiation. Six commonly used SSs; 4-t-butyl-4-methoxy dibenzoyl methane, 4-methoxycinnamic acid, 2-hydroxy-4-methoxybenzophenone (BZ-3), Dibenzoyl methane, 2,2′-dihydroxy-4-methoxy benzophenone (BZ-8) and p-methylbenzoic acid; are investigated. In this work, terbium chloride bioluminescent genosensor is used for sensitive, simple and inexpensive determination of induced DNA-damage. Results reveal that only BZ-3 and BZ-8 induced DNA-damage upon UV-irradiation that are confirmed by both absorption spectroscopy and viscosity measurements. Moreover, viscosity studies indicated the possible intercalation of the SS into DNA prior to initiation of DNA damage. Furthermore, the potency of BZ-3 and BZ-8 to induce DNA damage upon UVA irradiation was assessed on calf thymus DNA. The low cost of the proposed bioluminescent genosensor allows it to be an automatic simple process for the investigation of any DNA-drug interactions without the need of coupling with other analytical methods.

The inhibitory effect of aqueous and alcoholic extract of red pepper on some isolated pathogenic bacteria from different areas of human body

In most underdeveloped nations, traditional medicine, including herbal treatment, is still widely used. Due to the growth of antibiotic resistance, this study aims to use pepper as an anti-bacterial as alternative to antibiotics. Pepper is one of the most important plants used as a medicine for a long time in various countries and civilizations. This study aims to use pepper as an anti-bacterial in alternative to antibiotics. The current study included the inhibitory efficacy of aqueous and alcoholic red pepper extract on seven bacterial isolates: -Staphylococcus aureus, Streptococcus spp, Escherichia coli, Klebseilla spp, Salmonella spp, Pseudomonas aeruginosa, Proteus spp. These isolates were isolated from different pathologies and regions, and they were diagnosed according to the site of infection. Several antibiotics were also used as a standard control sample for germs. This study shows that the highest inhibitory Effect against E. coli bacterium, as the average inhibition diameter was about 16.5 mm, and it is an excellent inhibitory when compared to the antagonist's gentamicin and nitrofurantoin as it showed good inhibitory efficacy against the bacteria such as S. aureus P. aeruginosa, and Salmonella spp. While the effect on Klebsiella was equal, on the other hand, the aqueous extract did not show any efficacy against Proteus spp, as was shown in the results. The results also showed that Staph. Aureus bacteria were the most affected by the alcohol extract of the red pepper as it showed a high inhibition zone compared with the control sample tetracycline and nitrofurantoin. The plant's aqueous and alcoholic red pepper extracts were effective against the tested bacterial isolates. The plant's aqueous and alcoholic red pepper extract has good inhibitory efficacy against the studied bacterial isolates.

Skin biomechanical and viscoelastic properties measured with MyotonPRO in different areas of human body.

There is still a lack of clinically practical device, which allows to perform rapid and accurate examination of the skin condition. For this reason, suitability of the MyotonPRO for the assessment of skin biomechanical and viscoelastic parameters was evaluated in this study. The aim of the study was to establish the reference values of five parameters measured by MyotonPRO various locations of human skin. Oscillation frequency, dynamic stiffness, logarithmic decrement, mechanical stress relaxation and creep were measured at three different skin locations (clavicula, volar forearm and shin), using L-shape short and medium arm probes in 32 young female volunteers. Mean values of obtained parameters recorded by both probes were compared among three skin locations while reliabilities of measurements were assessed. Additionally, relationships between all recorded parameters were examined RESULTS: There were no statistically significant differences between the mean values of five measured parameters obtained with both probes in all investigated areas. However, statistically significant differences of mean values of almost all parameters measured among three places examined were found. Despite considerable differences in mean values of obtained parameters, there were visible strong correlations between some studied parameters in all three investigated areas of skin. It was demonstrated in all locations studied that the higher value of oscillation frequency corresponds to the higher value of dynamic stiffness, moreover such tissue recovers faster to its initial shape, and it was characterized by lower creep values. Such results indicate the existence of identical relationships between the same studied parameters in different areas of skin.

Automated Calculation of Height and Area of Human Body for Estimating Body Weight Using a Matlab-based Kinect Camera

ABSTRACT Body size is an important parameter in radiology examinations. Measurements of body size may be carried out remotely using a Kinect camera. We aim to develop a Matlab-based software that can be used to automatically measure the height and area in order to estimate the weight of a human body without direct contact. The size and depth of the image were calibrated for various object-Kinect distances. The depth image was segmented and normalized into a binary image, from which the height and area were calculated. The height and area of the body were correlated with the body weight. We analyzed the images obtained from 147 participants aged 5–70 years old and weighing 13.7–89.9 kg. The height measured using the Kinect camera had a high correlation with a ruler with R2 = 0.96 (p = 0.0096), and error percentage of 1.04%. It is also found that the height and area of the participants are well correlated with the weight of the participants with R2 of 0.453 and 0.658, respectively. A graphical user interface for automatically calculating the height and area of the human body has been successfully developed.

Intraoperative mapping of pre-central motor cortex and subcortex: a proposal for supplemental cortical and novel subcortical maps to Penfield\u2019s motor homunculus

Penfield’s motor homunculus describes a caricaturised yet useful representation of the map of various body parts on the pre-central cortex. We propose a supplemental map of the clinically represented areas of human body in pre-central cortex and a novel subcortical corticospinal tract map. We believe this knowledge is essential for safe surgery in patients with eloquent brain lesions. A single-institution retrospective cohort study of patients who underwent craniotomy for motor eloquent lesions with intraoperative motor neuromonitoring (cortical and subcortical) between 2015 and 2020 was performed. All positive cortical and subcortical stimulation points were taken into account and cartographic maps were produced to demonstrate cortical and subcortical areas of motor representation and their configuration. A literature review in PubMed was performed. One hundred and eighty consecutive patients (58.4% male, 41.6% female) were included in the study with 81.6% asleep and 18.4% awake craniotomies for motor eloquent lesions (gliomas 80.7%, metastases 13.8%) with intraoperative cortical and subcortical motor mapping. Based on the data, we propose a supplemental clinical cortical and a novel subcortical motor map to the original Penfield’s motor homunculus, including demonstration of localisation of intercostal muscles both in the cortex and subcortex which has not been previously described. The supplementary clinical cortical and novel subcortical motor maps of the homunculus presented here have been derived from a large cohort of patients undergoing direct cortical and subcortical brain mapping. The information will have direct relevance for improving the safety and outcome of patients undergoing resection of motor eloquent brain lesions.

Changes in the Distribution of Intrauterine Microbiota May Attribute to Immune Imbalance in the CBA/J×DBA/2 Abortion-Prone Mice Model.

Background: Female Genital Tract (FGT) is an important micro-ecological area of human body. Microbiota in the lower reproductive tract may subsequently invade the uterine cavity during embryo implantation and produce immune responses. CBA/J×DBA/2 mating combination has been widely used as an abortion-prone mice model but whether microbiota existed in their uterine cavity remains unclear. In this context, the role of the microbial communities in immune response deserves attention.Objective: To investigate the relationship between the distribution of microbiota in the uterine cavity of CBA/J×DBA/2 abortion-prone mouse model and the immune imbalance of the maternal-fetal interface.Methods: In this study, female CBA/J mice were paired with male DBA/2 mice to develop an abortion-prone model (BA group), and with male BALB/c mice to build a standard pregnancy model (BC group). The non-pregnant female mice were served as the control group (C group). Uterine flushing fluid and sera were collected on day 13.5 of pregnancy. 16S rRNA sequencing technology was used to analyze the distribution of intrauterine microbiota. Phylogenetic Investigation of Communities were conducted to predict the microbiota functions by Reconstruction of Unobserved States (PICRUST) and Kyoto Encyclopedia of Genes and Genomes (KEGG). The serum IL 10, INF-γ, and TNF-α levels were examined using Enzyme-linked immunosorbent assay (ELISA) method.Results: All samples were detected with microbial communities. The α diversity (p = 0.00077) had significant differences among three groups. Proteobacteria was the most dominant phylum in C group (mean = 83.21%) and BA group (mean = 43.23%). Firmicutes was dominant in BC group (mean = 46.4%), as well as the second dominant one in C group (mean = 12.63%) and BA group (mean = 40.55%). Microbiota functions were associated with metabolism and immune response through the NOD-like receptor signaling pathway. The serum IL 10 level in BA group were significantly lower than that in BC group (10.14 ± 1.90 pg/ml, n = 8; vs. 19.03 ± 1.82 pg/ml, n = 10; p = 0.004). The serum TNF-α and INF-γ level in BA group were also significantly higher than that in BC group (523.1 ± 58.14 pg/ml, n = 8 vs. 310.3 ± 28.51 pg/ml, n = 10, p = 0.0029; 69.22 ± 5.38 pg/ml, n = 8 vs. 50.85 ± 2.45 pg/ml, n = 10, p = 0.0042).Conclusion: Microbial communities were colonized in uterine cavity of CBA/J mice both at non-pregnant stage and pregnant stage when mated with both BALB/c and DBA/2 male mice. The differentially abundant microbiome may be attributed to the immune tolerance through binding to the NOD-like receptor.

A Review on Flexible Robotic Systems for Minimally Invasive Surgery

Recently, flexible robotic systems are developed to enhance minimally invasive interventions on internal organs located in confined areas of human body. These surgical devices are designed to navigate anatomical pathways via single-port access, such as natural orifices or minimal incisions and intraluminal interventions. With improved precision, spatial flexibility and dexterity, the robotic technology can enhance surgery such that minimally invasive flexible access would become a faster, safer, and more convenient method for intra-body interventions without multiple or wide incisions. However, a lot of works are still required for global acceptance of existing flexible robotic surgical platforms. This review provides extended insights on the design details of two types of flexible robotic systems used for endoscopic and endovascular procedures. As of today, several prototypes of both platforms have been proposed; however, their global acceptability and applicability remains very low. To address these, we present an extensive review on design constraints and control methods which are vital for safer, faster, and better operation of the flexible robotic systems in minimally invasive surgery (MIS). Finally, research trends of flexible robotic systems and their clinical application status in MIS are discussed along with some of the technical and technological challenges hindering their prominence.

Alternately Dipping Method to Prepare Graphene Fiber Electrodes for Ultra-high-Capacitance Fiber Supercapacitors.

SummaryFlexible fiber supercapacitors are promising candidate for power supply of wearable electronics. Fabrication of high-performance fibers is in progress yet challenging. The currently available graphene fibers made from wet-spinning or electro-deposition technologies are far away from practical applications due to their unsatisfactory capacitance. Here we report a facile alternately dipping (AD) method to coat graphene on wire-like substrates. The excellent mechanical properties of the substrate with greatly diverse choices can be carried over to the fiber supercapacitors. Under such guideline, the graphene fiber with a titanium core made by our AD method (AD:Ti@RGO) shows an ultra-high specific capacitance of up to 1,722.1 mF cm−2, which is ∼1,000 times that of wet-spinning- and electro-deposition-fabricated neat graphene fibers and presents the highest specific capacitance to date. With excellent mechanical properties and striking electrochemical performances, the AD:Ti@RGO-based supercapacitors light the path to the next-generation technologies for wearable devices.

Musculoskeletal Discomfort Evaluation using Quick Exposure Check (QEC) among Tower Crane Operators

Tower crane operators are at risk of developing Musculoskeletal Disorders (MSD) due to work schedules that require prolonged sitting with minimal movements. The aim of this study was to assess the discomfort levels associated with the musculoskeletal disorder and its severity on affected human body areas of tower crane operators while driving and handling of materials. This study was conducted amongst 32 tower crane operators at the construction sites of a high-rise building in Klang Valley. A Quick Exposure Check (QEC) was used to assess the MSDs levels and the affected severity on human body areas. The results from the QEC showed the body parts that were associated with a very high risk of MSDs were the back and neck. Other factors contributed to the high risk of MSDs among tower crane operators were identified as driving and vibration. MSDs among tower crane operators were evident from the QEC analysis. Therefore, it is essential to include ergonomic intervention in the workplace in order to minimize the risk.

Gadolinium deposition-"gadolinium deposition disease"

Gadolinium (Gd)-based contrast agents have been routinely used worldwide in diagnostic MRI since 1988. All routinely applied contrast agents for clinical use were considered extremely safe with regard to tolerance, adverse effects and diagnostic efficacy and when used at Food and Drug Administration-approved doses. With the identification of Gd-associated disorders, namely nephrogenic systemic fibrosis and adverse reactions, and in the longer term Gd-retention in the brain, this view changed and led to the withdrawal or restriction of approval of linear Gd chelates in Europe. Even though Gd deposition in different human body areas was described very early, recently published literature of intracerebral accumulation of contrast agents as well as deposition in bone have created surprising attention. Not only was the fact of Gd deposition in the body well known for many years, but there is currently no clinical evidence of patient symptoms and no resulting health issues of patients have been observed yet. The expression "gadolinium deposition disease" has been termed by active patient advocacy groups with an online presence with reports of individual members stating abroad spectrum of disorders yielding alarge symptom complex after administration of Gd-based contrast agents without evidence of any pre-existing or otherwise underlying disease process which could explain the mentioned disorder.

Time-effect reaction observation of micro-invasion embedded poly glycolide-co-lactide suture in Sanyinjiao (SP6) in healthy subjects by using magnetic resonance

To observe the time-effect of stimulation of the embedded poly glycolide-co-lactide (PGLA) suture in Sanyinjiao (SP6) area in normal human body, so as to provide an experimental evidence for clinical application of micro-invasion suture-embedding at an appropriate interval. A total of 8 healthy volunteer students (3 boys and 5 girls, ranging in age from 24 to 27 years) were recruited in the present study. A piece of sterilized PGLA suture was implanted into the left SP6 using minimally invasive surgery after strict local skin disinfection. The fat-suppression T2 weighted magnetic resonance images (MRI, displaying local lesion after eliminating interference of fat tissue signals), and T2 mapping 8-echo train images were acquired before and 8 h, 3, 7, 10 and 14 days after PGLA suture embedment by using a MR imaging system. After transformation of the T2-mapping 8-echo train images into T2-mapping images by using a relevant software, the T2 values (meaning the relaxation time of the local muscle) of the left SP6 were measured, followed by analysis of the signal intensity of T2 weighted fat-suppression images and T2 values at different time-points. Before the suture embedding, no abnormal signals were found in the signal intensity of T2 weighted fat-suppression images. After PGLA suture embedment, the local signal intensity of T2WI fat-suppression images was relatively increased at the 8th h, and on day 3, 7, 10 and 14 relevant to pre-embedment, but gradually atte-nuated on day 10 and 14. The T2 values were significantly increased at the 5 time-points of post-embedment (all P<0.01), but without significant differences among the 8thh, the 3rd and 7thd (P>0.05), and being markedly lowered on day 14 relevant to day 7 (P<0.01) in spite of being still markedly higher than that of pre-embedding (P<0.01). The signal intensity of T2 weighted fat-suppression images and T2 values acquired from PGLA-suture-embedded SP6 acupoint area in healthy subjects may keep at least for 2 weeks, suggesting that the stimulating reaction of suture-embedment persists more than 14 days. Hence, when a micro-invasion embedding with PGLA suture performed, the interval of two weeks would be appropriate.

The device forlight therapy with absorbed energy dose measuring

Light therapy conducting always connected with need to set optimal intensity of irradiating signal, modulation frequency and exposure. The better option is determination of dose absorbed by patient skin surface and frequency of the maximal absorption. At the same time the dose of falling signal energy is measured to protect patient from harmful effects (e.g. burns) of laser radiation. The authors developed a structural scheme of the device for light therapy and proposed an algorithm for converting and measuring signals by high-sensitive optical modulation radiometer. The scheme provides patient irradiation, measuring the dose of the absorbed energy in the irradiated areas of human body, for example, biologic active point, and determination of the maximal absorption frequencies. It increases the efficacy of the therapeutic procedure and allows to predict the result of treatment.

ENDOTHELIAL DYSFUNCTION: A CARDIOVASCULAR RISK FACTOR

Endothelium is one of the largest organ by area and consist of at least one trillion endothelial cells having more than 100 gram weight and covering more than 3000 square meters area in an adult human body. Endothelium interacts with most of the body systems and is implicated in end organ diseases particularly the cardiovascular. The endothelium maintains vascular tone by precisely regulating the vasodilatation and vasoconstriction while effectively providing the adequate supply of blood to the target organs. Factors that affect the endothelium and subsequently cardiovascular system include hypertension, smoking, obesity, hyperglycemia, hyperlipidemia, poor dietary habits and physical inactivity. Endothelial dysfunction is strongly associated with cardiovascular risk factors such as atherosclerosis, elevated level of low density lipoprotein oxidation, cytokine elaboration, up regulation of adhesion molecules, increased cell permeability, platelet aggregation as well as proliferation and migration of vascular smooth muscles. Endothelial dysfunction is a pathophysiological term used to indicate diminished production of nitric oxide and an imbalance in endothelial derived contraction and relaxation.

RETRACTED ARTICLE: Application of Monte Carlo calculation method based on special graph in medical imaging

With the rapid development of medical imaging technology and information technology, digital medical image acquisition equipment is constantly updated, especially the rise of proton medical technology, which has higher requirements on human diseased cell imaging technology. In this paper, based on the image data acquired by the large aperture CT, the Monte Carlo calculation and analysis of edge-blurred electronic density images have carried out to achieve accurate diagnosis and provide a new method for efficient pathological treatment. This article made a preliminary study and analysis on the application of Monte Carlo method in radio surgical treatment planning. Monte Carlo method, which is known as random sampling or statistical test methods, can truly simulate the actual physical process, problem solving and actual in good compliance. It can be very successful results. Combined with the image processing method, this paper carries out the detection methods of image pre-processing, image segmentation, feature extraction, classification and recognition to the lesion area of human body to realize the effective recognition of the special lesion image area. Experimental results show that the edge of lesion area has obtained by image segmentation, contour extraction and Monte-Carlo calculation. Particle-space information has taken as input. Based on Monte Carlo method, the space-absorbed dose in phantom is analysed distributed. By using the computerized liver cancer diagnosis technology, the doctor’s working pressure and labour intensity are reduced, the doctor’s working efficiency is improved, the accuracy of the diagnosis is improved, the hospital saves many expenses and the patient’s burden is reduced. Therefore, the research of computer-aided diagnosis has important significance and application value.

Essential Radiology for Medical Students, Interns and Residents by Ahuja AT et al. Kyiv, Ukraine: OMF Publishing, 2017

After a hard wok, it is finally here: radiologists deeply specialized in the diagnostics of head and neck disorders give the readers a possibility to touch the cutting-edge practical book Essential Radiology for Medical Students, Interns and Residents. The textbook is edited by Professor Ahuja AT, the most experienced world radiologist from Hong Kong (SAR). Content consists of ten Sections. 1st of which, Head &amp; Neck, is critically important to the specialists related with that area of human body. Uniqueness of that work ─ it consists of 1100 cine loops (CT, MRI scans, US images, etc.) connecting via QR codes. And to Head &amp; Neck Section belongs 111 of them covering the whole range of pathologic. In summary, I would not hesitate to recommend this book to anyone interested in making diagnosis as precise as possible.