Area For Stomach Cancer Research Articles

A note on the use of nitrate fertilizers in a high-risk geographical area for stomach cancer.

Chile being the only country in the world producing natural fertilizers (NaNO3 and KNO3), it uses very large quantities of them for agricultural purposes. Since in early 1970 Zaldívar first related the use of fertilizers to stomach cancer mortality, it is of key interest to know the amount of nitrogen fertilizers used, expressed in tons of N, by province, for the period from 1945 to 69. Of a total of 420,750 tons of N for the nation, 238,950 tons were used in the high-risk provinces for stomach cancer (Colchagua, Curicó, Talca, Maule, Linares, Nuble, Concepción, Bio-Bio, Arauco, Malleco, Cautín). On the other hand, in the low-risk provinces (Tarapacá, Antofagasta, Atacama, Magallanes) only 2,550 tons were used. In Chile, the use of fertilizers increased from 37,550 (1945-50) to 185,050 (1965-69) tons of N.

Histologic types of gastric carcinoma in high- and low-risk areas.

AbstractA total of 322 cases of gastric cancer from the surgical material of the Pathology departments of three cities in Colombia and of Mexico City were divided according to the histologic classification of Laurén into two main histologic types: intestinal and diffuse. The intestinal type was predominant in high‐risk areas for stomach cancer, while the diffuse type was more frequent in the low‐risk areas. Data presented suggest that these two main histologic types may be connected with different precancerous lesions as a significant proportion of the intestinal type carcinomas arose from intestinal metaplasia of the gastric mucosa, while the diffuse type showed no such origin. The significance of these findings in relation to the genesis of stomach cancer is discussed.