Background: Pain control is very important aspect of orthodontic practice. Aim: To compare the efficacy of music therapy for pain control following initial archwire placement in orthodontics. Methods: This randomized control trial was conducted at orthodontics department. The study consisted of 50 orthodontic subjects from 1.1.2019 to 1.30.2020. Purposive sampling technique was used. 25 were in control group while other 25 were randomly allocated to music group. The pain was recorded using VAS scale at multiple points of time following archwire placement. T-test was used for the statistical analysis. Results: The study found that there was insignificant difference in mean pain scores between the two groups with less pain scores in music group. Conclusion: Music can play an effective role in pain control following orthodontic initial bonding. Keywords: Music; Orthodontics.