Concurrence is viewed as the most commonly approach for quantifying entanglement of two-qubit states, while intrinsic concurrence contains concurrence of four pure states consisting of a special pure state ensemble concerning an arbitrary two-qubit state. Thus, a natural question arises: Whether there is a specified relation between them. We firstly examine the relation between concurrence and intrinsic concurrence for the maximally nonlocal mixed state under a special unitary operation, which is not yet rigorously proved. In order to obtain a general result, we investigate the relation between concurrence and intrinsic concurrence using randomly generated two-qubit states, and derive an inequality relation between them. Finally, we take into account the relation between concurrence and intrinsic concurrence in open systems, and reveal the ratio of the two quantum resources, which is only correlated with the experiencing channels.